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Operations 1 for CAVS

I9_CAVS_OPERATIONS1

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Operations: NOMESCO codes ^FMA|^FMB

1 out of 7 registries used, show all original rules.

93

4. Check minimum number of events

None

93

5. Include endpoints

None

93

6. Filter based on genotype QC (FinnGen only)

93

Control definitions (FinnGen only)

Control exclude
I9_CAVS

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 93 49 44
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 61.63 61.80 61.45

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
86
Matched controls
859
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2121.2
76.8
63
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
66.7
45.6
52
19
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
151.6
36.1
36
*
FMB10
NOMESCO Finland
Transannular expansion of aortic ostium
+∞
36.0
32
*
B01AA03
ATC
warfarin; systemic
22.1
35.0
65
105
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
36.5
35.0
46
26
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
+∞
31.1
28
*
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
+∞
29.9
27
*
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
+∞
29.9
27
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
16.1
28.5
56
89
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
15.0
27.7
58
104
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
14.6
25.2
49
71
WX872
NOMESCO Finland
Intensive care
28.7
24.8
34
19
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
11.6
23.2
55
114
Q23.11
ICD-10 Finland
Bicuspid aortic valve
+∞
21.8
20
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
31.3
19.1
25
11
GD1AA
NOMESCO Finland
Thorax X-ray examination
9.4
19.0
69
259
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
12.9
16.2
30
34
C07AB07
ATC
bisoprolol; oral
7.4
16.2
64
243
FMA20
NOMESCO Finland
Plastic repair of aortic valve for stenosis
+∞
16.1
15
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
14.6
15.7
27
26
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
15.0
14
*
FMB00
NOMESCO Finland
Supravalvular aortic expansion using patch
+∞
13.9
13
*
FMA32
NOMESCO Finland
Percutaneous transluminal expansion of aortic valve
+∞
13.9
13
*
C03CA01
ATC
furosemide; systemic
6.0
13.6
52
175
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
11.7
11
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
12.2
11.6
21
22
B01AB05
ATC
enoxaparin; parenteral
5.2
10.6
40
123
FMB96
NOMESCO Finland
Other expansion of aortic ostium
+∞
10.6
10
*
AP6
HP
Valveoplasty of the aortic valve
+∞
10.6
10
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
45.8
10.3
12
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
30.2
10.1
13
5
WX408
NOMESCO Finland
General anesthesy, balanced
4.6
9.8
44
160
AN1
HP
Coronary angiography
6.7
9.7
26
52
K83
ICPC
Heart valve disease NOS
34.4
9.7
12
*
AB2
HP
AVR bio, stent
+∞
9.5
9
*
ZXD05
NOMESCO Finland
Urgent procedure
4.5
9.5
45
169
ZXE40
NOMESCO Finland
More than seven and less than nine hours
18.2
9.4
14
9
TPH07
NOMESCO Finland
Cathetrisation of artery
6.1
9.3
27
60
ZXE20
NOMESCO Finland
More than three and less than five hours
5.6
9.1
29
72
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
7.6
8.9
21
35
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
99.4
8.6
9
*
XF402
NOMESCO Finland
ECG with work load test
6.7
8.5
22
42
ZXD10
NOMESCO Finland
Scheduled procedure
3.9
8.4
53
249
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
37.2
8.3
10
*
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
37.2
8.3
10
*
XF404
NOMESCO Finland
Ambulatory ECG
6.8
8.2
21
39
XF400
NOMESCO Finland
ECG with 12 standard connections
4.4
7.9
32
101
201
Kela drug reimbursment
Chronic cardiac insufficiency
8.7
7.6
16
22
I50.9
ICD-10 Finland
Heart failure, unspecified
4.6
7.5
28
81
ZXE10
NOMESCO Finland
More than one and less than three hours
3.6
7.1
44
195
AA1AD
NOMESCO Finland
CT of head and brain
4.2
7.1
30
98
XF600
NOMESCO Finland
Bloodpressure measurement
5.9
6.9
19
39
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
43.6
6.9
8
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
11.4
6.8
12
12
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
7.0
6.7
16
27
WX402
NOMESCO Finland
General anaesthesia
4.1
6.6
28
91
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
6.5
6.4
16
29
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
29.0
6.3
8
*
Q25.3
ICD-10 Finland
Stenosis of aorta
+∞
6.3
6
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
6.3
6
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
+∞
6.3
6
*
FMD22
NOMESCO Finland
Percutaneous transluminal replacement of aortic valve using biological prosthesis
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3032080) INR in Blood by Coagulation assay
71
266
8.06
19.54
33.6
8.2
inr
2.2
1.2
5.96
20
70
(3022217) INR in Platelet poor plasma by Coagulation assay
39
87
7.00
18.45
39.7
20.0
inr
2.4
1.2
—
10
12
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
21
23
11.50
18.04
36.7
6.0
u/ml
0.3
0.4
0.80
16
14
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
21
44
5.87
10.11
34.2
6.8
%
77.2
88.8
1.48
21
44
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
46
188
3.86
9.45
3.3
2.8
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
13
18
8.23
9.09
1.7
1.8
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
29
89
4.28
8.84
6.9
5.3
u/l
284.3
311.5
0.15
29
84
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
17
33
6.08
8.79
5.8
7.5
%
157.1
188.0
0.87
17
33
(3020779) Urea [Moles/volume] in Serum or Plasma
28
88
4.12
8.22
16.9
13.8
mmol/l
7.0
7.5
0.17
28
81
(3044640) Blood type and Crossmatch panel - Blood
51
242
3.45
8.03
3.4
3.0
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
59
337
3.05
6.30
4.9
4.5
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
51
284
2.76
5.47
4.1
3.9
ng/l
287.8
42.4
2.00
35
203
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
60
382
2.61
4.65
6.7
8.7
umol/l
16.6
14.2
0.29
55
361
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
23
92
2.99
4.47
10.9
15.8
mmol/l
25.0
24.4
0.40
23
92
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
12
31
4.30
4.41
19.3
14.9
—
—
—
0
0
(3000991) Gas panel - Venous blood
24
107
2.68
3.79
13.3
12.1
—
—
—
0
0
(3022313) Gas panel - Capillary blood
18
69
2.99
3.73
10.7
12.1
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
25
120
2.48
3.38
2.6
2.0
—
—
—
0
0
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
6
7
9.05
3.31
5.3
9.3
%
84.2
87.0
—
6
7
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
28
143
2.37
3.31
10.5
3.3
mg/l
2.4
1.8
0.17
20
119
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
12
40
3.30
3.10
16.2
12.7
mmol/l
24.0
24.8
0.44
12
35
(3014576) Chloride [Moles/volume] in Serum or Plasma
22
104
2.46
3.05
6.5
10.1
mmol/l
106.6
104.2
1.30
22
98
(3023368) Bacteria identified in Blood by Culture
35
205
2.13
2.95
5.3
4.4
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
7
14
5.31
2.78
9.1
4.6
kpa
8.7
8.8
—
7
14
(3013290) Carbon dioxide [Partial pressure] in Blood
7
14
5.31
2.78
9.1
4.6
kpa
5.4
4.9
—
7
14
(3019230) Fractional oxyhemoglobin in Venous blood
7
15
4.95
2.65
4.1
29.2
%
65.9
69.6
—
7
15
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
19
90
2.40
2.61
11.9
10.7
kpa
5.0
5.0
0.29
19
81
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
9
26
3.72
2.56
1.8
2.1
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
22
113
2.24
2.52
1.7
2.0
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
53
377
1.94
2.50
7.5
9.5
e9/l
0.0
0.0
0.90
46
317
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
9
27
3.58
2.46
1.9
2.4
—
—
—
0
0
(1616796) Gas panel - Central venous blood
7
17
4.36
2.41
4.4
3.7
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
6
13
4.85
2.31
1.3
1.5
—
—
—
0
0
(3010421) pH of Blood
7
20
3.70
2.10
10.3
4.0
ph
7.4
7.4
—
7
14
(3013115) Eosinophils [#/volume] in Blood
53
392
1.82
2.08
8.9
9.9
e9/l
0.2
0.2
0.32
47
336
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
6
15
4.20
2.07
1.0
1.7
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
19
101
2.11
1.99
2.8
1.9
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
23
132
1.99
1.97
22.0
10.6
mmol/l
1.2
1.2
0.33
23
122
(44790047)
6
16
3.93
1.97
1.7
2.1
—
—
—
0
0
(44806118)
6
16
3.93
1.97
1.7
2.1
—
—
—
0
0
(44790048)
6
16
3.93
1.97
1.7
2.1
—
—
—
0
0
(44790049)
6
16
3.93
1.97
1.7
2.1
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
51
378
1.77
1.95
7.7
9.4
e9/l
0.6
0.6
0.54
45
317
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
36
243
1.79
1.88
4.0
4.0
u/l
49.3
32.7
0.44
36
237
(3013512) EKG study
31
201
1.81
1.84
6.1
3.9
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
10
41
2.61
1.82
1.2
1.6
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
7
24
3.07
1.76
5.9
19.4
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
14
69
2.21
1.75
13.9
12.8
kpa
10.0
9.5
0.59
14
63
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
7
25
2.94
1.68
1.6
2.1
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
51
390
1.68
1.65
8.0
9.4
e9/l
1.6
1.9
3.12
45
334
(3003694) ABO and Rh group [Type] in Blood
30
199
1.75
1.63
1.4
1.5
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
7
26
2.83
1.61
1.6
2.2
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
21
125
1.88
1.61
5.4
10.3
mmol/l
1.9
1.6
0.20
16
92
(3044889) 12 lead EKG panel
58
463
1.67
1.56
6.1
3.8
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
28
187
1.71
1.47
2.6
3.0
mg/l
2.7
3.1
0.46
22
162
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
23
2.72
1.39
1.8
2.7
—
—
—
0
0
(3019060) Gas panel - Arterial blood
9
44
2.16
1.31
8.4
3.7
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
54
436
1.57
1.29
10.3
13.7
e9/l
4.4
4.0
0.77
49
376
(3014111) Lactate [Moles/volume] in Serum or Plasma
15
86
1.89
1.28
15.7
12.4
mmol/l
1.0
1.4
2.04
15
80
(3002256) Pathology report gross observation
14
81
1.86
1.17
1.6
1.2
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
36
271
1.54
1.14
9.9
9.4
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
15
90
1.79
1.12
1.9
2.5
nmol/l
426.6
320.3
1.40
15
84
(3027273) Bicarbonate [Moles/volume] in Venous blood
8
41
2.04
1.12
5.3
3.9
mmol/l
25.9
24.6
—
8
41
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
46
367
1.50
1.11
13.4
10.5
mmol/l
1.2
1.2
1.41
39
312
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
5
21
2.46
1.10
1.0
2.2
—
—
—
0
0
(3020891) Body temperature
7
34
2.14
1.05
8.9
4.9
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
9
49
1.92
1.02
3.9
11.6
%
1.4
1.5
—
9
49
(3000492) Spirometry study
9
51
1.85
0.98
1.7
1.5
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
10
55
1.92
0.96
6.0
10.5
g/l
122.0
121.7
—
10
55
(3020630) Protein [Mass/volume] in Serum or Plasma
11
63
1.85
0.95
1.6
3.4
g/l
63.1
65.5
0.51
11
57
(3000494) Fungus identified in Specimen by Culture
14
87
1.72
0.94
1.5
1.4
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
13
81
1.70
0.86
1.6
1.8
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
13
81
1.70
0.86
1.5
1.7
—
—
—
0
0
(3023323) Follitropin [Units/volume] in Serum or Plasma
0
27
0.00
0.79
0.0
1.6
—
16.9
—
0
20
(3035637) Corticotropin [Mass/volume] in Plasma
5
24
2.14
0.76
1.2
1.7
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
22
282
0.71
0.65
2.1
2.0
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
10
63
1.66
0.65
4.7
4.3
—
—
—
0
0
(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid
0
20
0.00
0.61
0.0
4.8
—
313.1
—
0
15
(3016543) Leukocytes [#/volume] in Cerebral spinal fluid
0
20
0.00
0.61
0.0
4.7
—
3.5
—
0
15
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
22
0.00
0.60
0.0
1.6
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
10
145
0.65
0.56
3.4
3.9
e6/l
1.1
1.0
—
5
98
(40760892) CBC W Ordered Manual Differential panel - Blood
19
146
1.38
0.52
2.5
6.6
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
61
662
0.77
0.51
5.0
4.5
mmol/l
5.7
6.0
1.94
56
596
(3005719) IgG [Mass/volume] in Serum or Plasma
11
77
1.49
0.48
4.0
2.9
g/l
9.6
8.8
0.31
11
71
(21494755) Public health laboratory ask at order entry panel
7
49
1.46
0.47
1.4
1.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
21
257
0.76
0.45
5.1
4.7
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
8
55
1.50
0.44
2.5
1.5
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
4.1
—
65.8
—
0
16
(3006598) pH of Arterial cord blood
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
(3003932) Carbon dioxide [Partial pressure] in Arterial cord blood
0
17
0.00
0.41
0.0
1.0
—
7.9
—
0
10
(3021706) Oxygen [Partial pressure] in Arterial cord blood
0
17
0.00
0.41
0.0
1.0
—
2.8
—
0
10
(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood
0
18
0.00
0.40
0.0
1.0
—
19.0
—
0
18
(3008295) Osmolality of Serum or Plasma
0
18
0.00
0.40
0.0
1.1
—
278.2
—
0
12
(3021589) Normoblasts [#/volume] in Blood
40
353
1.23
0.40
16.3
12.7
e9/l
0.0
0.0
0.00
34
285
(3030467) Casts [#/volume] in Urine by Automated count
19
232
0.77
0.40
4.2
4.5
e6/l
0.1
0.3
1.97
14
181
(3041096) Erythrocytes [Presence] in Urine by Automated
15
189
0.75
0.39
5.8
4.1
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
9
70
1.32
0.38
2.4
1.8
g/l
0.9
1.0
—
9
65
(3012516) Albumin [Mass/volume] in Urine
23
196
1.23
0.31
2.9
3.3
mg/l
49.2
66.7
0.18
15
133
(3021879) Hepatitis B virus core Ab [Presence] in Serum
7
56
1.27
0.30
1.3
1.5
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
7
56
1.27
0.30
5.1
4.0
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
25
216
1.22
0.30
3.0
3.0
u/l
60.0
62.4
0.09
25
203
(3018418) pH of Serum or Plasma
23
197
1.22
0.29
9.7
5.0
ph
7.4
7.4
—
7
37
(3021601) Nitrite [Presence] in Urine by Test strip
31
346
0.84
0.27
6.6
6.0
estimate
0.0
0.0
—
7
63
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
64
605
1.19
0.27
19.2
15.1
ml/min/173m2
78.7
79.5
0.09
58
485
(40761511) CBC panel - Blood by Automated count
79
762
1.24
0.25
25.8
14.0
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
6
81
0.72
0.25
2.2
1.4
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
62
652
0.85
0.25
5.8
4.5
mmol/l
1.3
1.5
3.20
57
587
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
11
135
0.79
0.24
3.2
4.1
e6/l
1.0
2.0
—
5
90
(40768797) Stomach Pathology biopsy report
7
92
0.74
0.24
1.1
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(4146454)
0
11
0.00
0.21
0.0
3.0
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
10
0.00
0.21
0.0
3.7
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
24
213
1.17
0.21
2.5
3.5
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
0
14
0.00
0.20
0.0
6.1
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3022621) pH of Urine by Test strip
6
50
1.21
0.20
8.5
2.9
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
6
50
1.21
0.20
9.5
3.7
%
52.3
50.4
—
6
50
(3031040) Bacteria [#/volume] in Urine by Automated count
50
471
1.13
0.19
3.7
5.1
—
5050.7
—
0
11
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
77
746
1.19
0.19
26.1
15.9
mg/l
34.1
22.0
2.45
72
562
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
18
157
1.18
0.19
1.6
1.8
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
51
482
1.13
0.18
3.1
3.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
5
67
0.73
0.17
1.2
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
5
68
0.72
0.17
1.6
1.8
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
8
99
0.79
0.14
16.8
8.1
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
20
181
1.13
0.13
1.9
1.5
g/l
1.5
1.9
1.33
15
108
(3020682) Albumin/Creatinine [Ratio] in Urine
22
201
1.12
0.13
4.3
4.2
mg/mmol
9.5
6.7
0.14
13
132
(3035350) Ketones [Presence] in Urine by Test strip
32
340
0.91
0.12
3.4
4.5
estimate
0.0
0.0
—
7
60
(1761868) Lipid panel - Serum or Plasma
23
213
1.11
0.10
3.1
3.0
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
33
348
0.92
0.10
4.3
4.4
estimate
0.0
0.0
—
7
57
(4010399)
5
45
1.12
0.10
1.0
1.4
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
16
174
0.90
0.08
1.1
1.5
u/ml
1.4
1.2
—
5
37
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
8
74
1.09
0.08
1.9
1.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
12
132
0.90
0.07
1.8
1.9
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
8
94
0.84
0.07
1.5
4.0
ug/g
49.4
143.6
—
8
73
(3021960) Folate [Moles/volume] in Serum or Plasma
15
162
0.91
0.06
1.3
1.5
nmol/l
20.5
21.0
0.05
15
138
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
10
90
1.12
0.06
1.8
1.7
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
19
179
1.08
0.05
3.8
4.9
estimate
0.0
0.0
—
5
61
(3011397) Hemoglobin [Presence] in Urine by Test strip
16
169
0.94
0.03
2.9
4.2
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
65
658
0.96
0.02
5.7
4.5
mmol/l
4.3
4.5
1.30
60
600
(3002582) Erythrocytes [#/volume] in Urine
24
247
0.96
0.01
3.8
4.9
e6/l
17.0
30.2
1.04
18
195
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
28
273
1.04
0.01
1.6
2.0
pmol/l
105.5
91.3
0.78
16
128
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
63
637
0.97
0.01
5.5
4.1
mmol/l
1.4
1.3
0.92
58
569
(3037467) Urinalysis macro (dipstick) panel - Urine
49
497
0.97
0.01
4.0
4.9
—
—
—
0
0
(3015736) pH of Urine
27
264
1.03
0.00
2.3
4.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
27
276
0.97
0.00
3.6
4.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
10
102
0.98
0.00
1.9
1.5
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
17
168
1.01
0.00
4.9
4.6
%
31.0
22.6
—
9
85
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
66
661
0.99
0.00
4.4
4.5
mu/l
2.0
2.0
0.15
61
584
(36304419) Bacteria [Presence] in Urine
22
223
0.98
0.00
4.0
4.4
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
28
277
1.02
0.00
4.1
5.5
e6/l
12.0
86.8
2.00
19
208
(40758558) Short blood count panel - Blood
23
225
1.03
0.00
6.1
9.6
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
68
684
0.98
0.00
35.0
18.2
%
36.1
39.4
1.44
48
508
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042299) inFLIXimab [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
19.4
—
7.2
—
0
5
(4024509)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40757494) Bilirubin.total [Moles/volume] in Blood
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3003752) BK virus DNA [Units/volume] (viral load) in Urine by NAA with probe detection
0
5
0.00
0.00
0.0
8.0
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
1.7
—
0
5
(3001964) Herpes simplex virus Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(42869858) Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001684) Respiratory syncytial virus Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3016031) Almond IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
2.3
—
0
5
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3017115) Methotrexate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
42.4
—
0.6
—
0
5
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
17.0
—
0
5
(3035320) C reactive protein [Mass/volume] in Body fluid
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3047189) Immunofixation for 24 hour Urine
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3032390) JC virus DNA [#/volume] (viral load) in Urine by NAA with probe detection
0
5
0.00
0.00
0.0
8.0
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
2.3
—
1.4
—
0
9
(3029075) Extractable nuclear Ab panel - Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3027901) Hemoglobin [Mass/volume] in Arterial cord blood
0
6
0.00
0.00
0.0
1.0
—
170.0
—
0
6
(3014271) Vancomycin [Susceptibility]
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3032352) Blasts [#/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
7.2
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
0
9
0.00
0.00
0.0
9.0
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045683) HLA typing for celiac disease panel - Blood or Tissue
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3013336) Amino acids [Identifier] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
3.3
—
—
—
0
0
(4027681)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
3.3
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
7
0.00
0.00
0.0
6.9
—
225.1
—
0
7
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
1.2
—
0
6
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
12
120
1.00
0.00
1.9
1.7
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(1175556) inFLIXimab Ab [Units/volume] in Serum by Immunoassay
0
6
0.00
0.00
0.0
13.5
—
—
—
0
0
(4035726)
6
69
0.86
0.00
2.3
1.5
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
0
7
0.00
0.00
0.0
7.3
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
8
86
0.92
0.00
9.9
4.7
%
31.9
32.7
—
8
45
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
8
0.00
0.00
0.0
5.0
—
—
—
0
0
(3045781) Inhibin B [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
151.0
—
0
6
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045462) Protein/Creatinine [Ratio] in Urine
0
7
0.00
0.00
0.0
22.3
—
251.7
—
0
7
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
8
0.00
0.00
0.0
7.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: I9_CAVS_OPERATIONS1 – Operations 1 for CAVS

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).