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Haemophilus septicemia

DOID EFO Endpoint Browser PheWeb

HAEMOPHIL_SEPTICHE

Pasteurella hemorrhagic septicemia: Any of several bacterial diseases, usually caused by pasteurella multocida, marked by the presence of hemorrhagic areas in the subcutaneous tissues, serous membranes, muscles, lymph glands, and throughout the internal organs. The diseases primarily affect animals and rarely humans.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A41.3
  • Hospital discharge: ICD-9 — 0384A
  • Cause of death: ICD-10 — A41.3
  • Cause of death: ICD-9 — 0384A

2 out of 7 registries used, show all original rules.

67

4. Check minimum number of events

None

67

5. Include endpoints

None

67

6. Filter based on genotype QC (FinnGen only)

67

Control definitions (FinnGen only)

Control exclude
ASTHMA_SEPTICHE_PNEUMONIA

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
A41
Name in latin
Septic(h)aemia ab Haemophilo influenzae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 634 322 306
Only index persons 485 264 221
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 61.69 65.59 57.45
Only index persons 60.23 65.06 54.47

-FinnGen-

Key figures

All Female Male
Number of individuals 67 33 34
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 56.68 52.54 60.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
62
Matched controls
619
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A41.3
ICD-10 Finland
Sepsis due to Haemophilus influenzae
+∞
65.8
51
*
0384A
ICD-9 Finland
Septicaemia due to other gram-negative organisms[SEPTICHAEMIA HAEMOPHILUS INFLUENZAE]
+∞
11.8
11
*
J14
ICD-10 Finland
Pneumonia due to Haemophilus influenzae
+∞
10.7
10
*
A41.9
ICD-10 Finland
Sepsis, unspecified
13.5
8.3
14
13
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.9
7.6
30
99
J01MA12
ATC
levofloxacin; systemic
4.7
6.4
24
73
J01FF01
ATC
clindamycin; systemic
4.3
6.2
27
95

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3023368) Bacteria identified in Blood by Culture
39
138
5.37
10.75
8.8
4.0
—
—
—
0
0
(3012544) pH of Venous blood
18
48
4.76
6.61
16.7
5.8
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
15
39
4.67
5.62
3.1
1.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
16
51
3.81
4.56
3.1
1.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
17
57
3.66
4.51
3.5
1.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
22
88
3.23
4.45
2.5
1.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
28
130
2.98
4.39
10.5
6.9
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
16
53
3.65
4.31
1.9
1.8
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
17
61
3.39
4.05
3.6
1.6
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
9
15
6.74
3.96
2.3
3.7
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
36
203
2.67
3.79
5.4
2.4
ug/l
155.4
116.9
0.51
36
187
(3042936) Bacteria identified in Isolate by Culture
18
70
3.15
3.76
3.9
1.6
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
7
9
8.52
3.65
1.4
1.4
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
6
6
10.81
3.57
1.2
1.5
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
7
11
6.95
3.27
1.9
1.0
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
7
11
6.95
3.27
1.9
1.0
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
20
89
2.78
3.27
3.3
1.7
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
30
165
2.48
3.20
15.3
5.3
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
10
29
3.88
3.18
4.7
2.5
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
40
252
2.46
3.16
22.8
6.4
mmol/l
1.2
1.2
1.00
34
214
(3000991) Gas panel - Venous blood
13
46
3.27
3.12
24.6
6.6
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
5
5
10.65
3.02
1.6
2.0
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
6
9
7.19
2.93
8.0
11.6
—
—
—
0
0
(3026782) Osmolality of Urine
21
102
2.54
2.86
4.4
2.5
mosm/kgh2o
482.5
520.6
0.44
21
91
(3007164) IgA [Mass/volume] in Serum or Plasma
21
103
2.51
2.80
2.0
1.4
g/l
2.4
2.3
0.10
15
60
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
16
70
2.69
2.66
2.1
1.7
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
25
136
2.34
2.65
8.4
2.6
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
11
5.87
2.60
3.3
1.2
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
9
26
3.83
2.59
3.1
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
7
177
0.33
2.54
3.0
3.0
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
17
80
2.51
2.44
7.4
2.1
umol/l
10.8
14.7
1.32
17
67
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
5
9
5.90
2.25
3.2
1.3
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
37
249
2.09
2.24
13.6
5.1
e9/l
0.7
0.6
0.67
31
222
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
19
3.99
2.21
1.0
1.1
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
37
251
2.06
2.17
13.6
5.1
e9/l
0.0
0.0
0.67
31
224
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
29
181
2.06
2.12
7.4
2.7
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
34
226
2.02
2.09
8.5
7.2
inr
1.3
1.3
—
7
75
(3024561) Albumin [Mass/volume] in Serum or Plasma
33
219
2.00
2.02
14.8
4.4
g/l
31.5
35.3
2.85
33
209
(3019198) Lymphocytes [#/volume] in Blood
37
257
1.98
1.98
13.6
5.1
e9/l
1.9
1.8
0.22
31
229
(3034770) Mitochondria Ab [Titer] in Serum
5
11
4.81
1.97
1.0
1.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
29
185
2.00
1.97
2.6
1.9
pmol/l
91.2
97.0
0.32
20
88
(3011397) Hemoglobin [Presence] in Urine by Test strip
21
120
2.09
1.91
5.0
3.8
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
27
170
1.99
1.89
4.4
3.1
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
37
262
1.92
1.82
15.1
5.4
e9/l
0.2
0.2
0.25
32
233
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
12
55
2.44
1.80
6.5
2.3
u/l
20.1
27.4
0.86
12
47
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
18
3.55
1.79
1.7
1.2
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
18
3.55
1.79
1.7
1.2
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
29
191
1.91
1.76
9.8
3.3
e6/l
20.8
62.7
0.94
24
127
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
8
31
2.79
1.72
44.3
8.2
mmol/l
26.7
24.5
—
8
31
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
6
19
3.36
1.70
1.3
1.8
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
5
14
3.77
1.64
2.4
1.6
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
7
26
2.88
1.63
8.7
6.1
%
0.9
1.5
—
7
26
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
38
279
1.84
1.61
12.3
5.8
umol/l
10.5
13.4
0.95
38
264
(3021879) Hepatitis B virus core Ab [Presence] in Serum
8
33
2.61
1.59
1.8
1.7
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
26
171
1.85
1.55
3.7
2.0
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
5
15
3.51
1.55
1.4
1.1
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
5
15
3.51
1.55
7.4
5.5
%
252.2
187.9
—
5
15
(3019060) Gas panel - Arterial blood
9
37
2.65
1.55
8.8
4.6
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
20
121
1.93
1.53
2.3
1.5
nmol/l
18.8
21.2
0.32
20
99
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
5
16
3.29
1.46
10.0
1.9
u/ml
19.4
30.9
—
5
16
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
5
16
3.29
1.46
1.4
1.4
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
40
0.00
1.38
0.0
1.8
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
30
213
1.74
1.36
22.4
9.7
e9/l
0.0
0.0
0.47
25
179
(3014007) Fractional oxyhemoglobin in Arterial blood
8
38
2.25
1.23
11.3
7.6
%
92.5
92.7
—
8
38
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
18
113
1.81
1.22
3.9
1.9
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
20
2.62
1.17
7.6
3.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
8
40
2.13
1.16
1.8
1.8
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
14
82
1.89
1.16
8.6
3.1
mmol/l
0.8
0.8
0.54
14
77
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
11
59
2.03
1.15
6.1
3.2
—
—
—
0
0
(3015736) pH of Urine
28
203
1.65
1.14
4.7
3.8
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
5
22
2.37
1.05
2.8
1.8
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
7
36
2.05
1.00
1.4
1.1
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
7
36
2.05
1.00
1.4
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
30
0.00
1.00
0.0
1.5
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
0
31
0.00
0.99
0.0
1.2
—
147.6
—
0
8
(3037467) Urinalysis macro (dipstick) panel - Urine
42
345
1.58
0.98
9.8
4.5
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
40
326
1.56
0.96
10.9
4.7
mmol/l
7.0
6.6
0.52
40
307
(3022217) INR in Platelet poor plasma by Coagulation assay
12
72
1.81
0.92
38.6
29.5
—
1.6
—
0
6
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
13
82
1.73
0.86
10.8
2.7
e6/l
8.4
5.0
—
8
40
(3002385) Erythrocyte distribution width [Ratio]
49
426
1.56
0.81
54.0
16.6
%
14.7
13.8
2.46
49
417
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
6
33
1.90
0.81
2.0
2.3
—
—
—
0
0
(1002224) Polysomnography panel
0
25
0.00
0.81
0.0
1.1
—
—
—
0
0
(3002256) Pathology report gross observation
10
60
1.78
0.77
1.5
1.4
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
7
38
1.94
0.76
1.3
1.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
13
85
1.66
0.76
10.8
2.5
e6/l
0.9
1.0
—
8
43
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
27
1.92
0.70
16.8
8.1
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
21
161
1.44
0.62
3.6
3.1
ng/l
2215.6
1184.1
0.59
21
132
(3027944) Amphetamines [Presence] in Urine
0
19
0.00
0.61
0.0
1.3
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
8
54
1.55
0.60
2.4
4.5
ug/l
3.2
24.3
—
8
42
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
30
247
1.39
0.60
7.2
3.8
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
44
387
1.40
0.58
20.6
6.9
u/l
99.5
80.2
1.12
44
361
(3000494) Fungus identified in Specimen by Culture
9
62
1.52
0.56
2.3
1.3
—
—
—
0
0
(3035941) MCH [Entitic mass]
53
569
0.67
0.55
61.5
20.0
pg
29.8
30.2
0.71
53
562
(3010813) Leukocytes [#/volume] in Blood
53
569
0.67
0.55
61.7
20.2
e9/l
8.3
6.7
2.16
53
551
(3026361) Erythrocytes [#/volume] in Blood
53
569
0.67
0.55
61.6
20.1
e12/l
4.2
4.5
3.82
53
551
(3000963) Hemoglobin [Mass/volume] in Blood
53
569
0.67
0.55
61.8
20.3
g/l
122.2
135.4
6.53
53
561
(3024731) MCV [Entitic volume]
53
568
0.68
0.52
61.6
20.1
fl
90.8
90.6
0.08
53
561
(3007461) Platelets [#/volume] in Blood
53
568
0.68
0.52
61.6
20.2
e9/l
258.2
247.0
0.41
53
555
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
7
46
1.58
0.50
1.9
2.1
—
—
—
0
0
(3000492) Spirometry study
7
50
1.45
0.46
1.1
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
37
327
1.29
0.42
4.0
3.2
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
(4035726)
7
51
1.42
0.33
2.1
1.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
7
51
1.42
0.33
2.6
2.3
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
23
201
1.22
0.26
3.5
3.9
ng/l
59.6
32.8
0.48
16
144
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
43
458
0.83
0.24
4.6
4.6
mu/l
1.9
1.9
0.03
43
417
(3041096) Erythrocytes [Presence] in Urine by Automated
12
145
0.79
0.24
4.0
3.8
—
—
—
0
0
(3013512) EKG study
12
145
0.79
0.24
4.7
3.7
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
11
0.00
0.21
0.0
1.7
—
2.1
—
0
6
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(4094501)
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
1.5
—
33.4
—
0
14
(40760892) CBC W Ordered Manual Differential panel - Blood
13
110
1.23
0.19
10.5
4.5
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
50
520
0.85
0.16
58.0
16.0
mmol/l
138.7
139.6
2.15
50
510
(3020564) Creatinine [Moles/volume] in Serum or Plasma
52
538
0.85
0.15
49.4
15.8
umol/l
98.6
77.3
1.45
52
538
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
53
547
0.85
0.14
22.6
9.8
u/l
22.4
25.9
1.49
53
529
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
5
47
1.07
0.09
2.4
2.9
ug/l
4.3
5.7
—
5
39
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
5
47
1.07
0.09
1.4
1.6
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
6
56
1.08
0.09
1.2
1.4
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
5
63
0.78
0.08
3.8
2.2
nmol/l
1635.2
443.4
—
5
57
(3009542) Hematocrit [Volume Fraction] of Blood
46
474
0.91
0.08
56.0
14.9
%
37.1
40.0
1.36
37
355
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
9
86
1.05
0.07
1.7
1.6
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
9
104
0.84
0.07
1.6
1.7
pmol/l
518.3
448.7
—
9
92
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
38
369
1.07
0.05
3.4
4.1
pmol/l
14.7
14.7
0.02
38
339
(40761511) CBC panel - Blood by Automated count
53
539
0.92
0.04
36.1
13.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
14
149
0.92
0.04
1.6
1.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
21
201
1.07
0.03
3.8
4.2
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
13
122
1.08
0.03
2.2
1.9
mmol/l
1.5
1.4
0.29
13
101
(3044889) 12 lead EKG panel
35
357
0.96
0.01
5.1
3.8
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
48
474
1.04
0.00
37.8
12.3
ml/min/173m2
76.4
80.6
0.47
43
393
(40768804) Tissue Pathology biopsy report
20
196
1.03
0.00
3.5
2.2
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
16.0
—
0
8
(3048689) Calprotectin [Mass/mass] in Stool
6
66
0.90
0.00
4.8
1.8
ug/g
61.3
111.3
—
6
52
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
68.4
—
0
5
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
3.1
—
4.2
—
0
7
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
3.7
—
17.3
—
0
9
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
5
58
0.85
0.00
22.2
9.1
—
—
—
0
0
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3001788) Aldosterone [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.0
—
246.0
—
0
7
(3000034) Microalbumin [Mass/volume] in Urine
0
7
0.00
0.00
0.0
4.4
—
30.5
—
0
7

Mortality – FinRegistry

↥

Association

Association between endpoint HAEMOPHIL_SEPTICHE and mortality.

Females

Parameter HR [95% CI] p-value
HAEMOPHIL_SEPTICHE 3.291 [1.69, 6.41] < 0.001
Birth year 0.999 [0.99, 1.01] 0.79

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 192 females with HAEMOPHIL_SEPTICHE died.

Males

Parameter HR [95% CI] p-value
HAEMOPHIL_SEPTICHE 3.733 [1.8, 7.73] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 182 males with HAEMOPHIL_SEPTICHE died.

Mortality risk

Mortality risk for people of age

years, who have HAEMOPHIL_SEPTICHE.

N-year risk Females Males
1 0.445% 0.698%
5 2.386% 3.852%
10 5.776% 9.398%
15 10.766% 17.086%
20 18.101% 28.376%

Relationships between endpoints

↥

Index endpoint: HAEMOPHIL_SEPTICHE – Haemophilus septicemia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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