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Tympanosclerosis

DOID Endpoint Browser PheWeb

H8_TYMPSCLE

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H74.0
  • Hospital discharge: ICD-9 — 3850
  • Cause of death: ICD-10 — H74.0
  • Cause of death: ICD-9 — 3850

2 out of 7 registries used, show all original rules.

72

4. Check minimum number of events

None

72

5. Include endpoints

None

72

6. Filter based on genotype QC (FinnGen only)

72

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H74
Name in latin
Tympanosclerosis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 655 366 286
Only index persons 602 343 259
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 39.64 44.87 32.79
Only index persons 38.70 43.91 31.80

-FinnGen-

Key figures

All Female Male
Number of individuals 72 47 25
Unadjusted period prevalence (%) 0.01 0.02 0.01
Median age at first event (years) 45.51 45.56 45.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
69
Matched controls
687
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H74.0
ICD-10 Finland
Tympanosclerosis
+∞
72.0
56
*
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
14.0
13
*
DCD00
NOMESCO Finland
Myringoplasty
+∞
14.0
13
*
3850A
ICD-9 Finland
Other disorders of middle ear and mastoid, Tympanosclerosis
+∞
14.0
13
*
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
+∞
14.0
13
*
UDC00
NOMESCO Finland
Ear microscopy
10.6
9.3
18
22
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
102.0
8.6
9
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
+∞
8.5
8
*
DCD10
NOMESCO Finland
Tympanoplasty
+∞
8.5
8
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
+∞
8.5
8
*
DFF00
NOMESCO Finland
Pure tone audiometry
9.7
7.6
15
19
Z01.1
ICD-10 Finland
Examination of ears and hearing
5.1
6.5
21
54
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
7
17
4.44
2.42
4.6
2.3
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
5
8
6.61
2.41
8.2
3.3
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
5
11
4.79
1.97
1.6
1.3
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
17
261
0.54
1.36
5.0
3.8
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
12
65
2.02
1.22
1.1
1.5
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
33
2.24
1.09
1.3
1.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
9
155
0.52
1.04
1.1
1.4
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
10
54
1.99
1.02
1.2
1.4
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
24
171
1.61
1.01
4.7
5.0
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
21
147
1.61
0.94
3.7
3.3
mg/l
64.8
50.4
0.13
13
96
(3020682) Albumin/Creatinine [Ratio] in Urine
22
160
1.54
0.84
4.2
3.8
mg/mmol
26.6
7.8
0.44
13
100
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
24
0.00
0.81
0.0
5.5
—
24.8
—
0
24
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
46
397
1.44
0.71
3.2
3.1
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
5
27
1.91
0.70
1.4
2.6
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
5
28
1.84
0.67
1.4
2.5
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
5
28
1.84
0.67
1.4
2.5
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
5
28
1.84
0.67
1.4
2.6
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
5
30
1.71
0.62
12.2
6.0
%
91.5
93.4
—
5
30
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
16
0.00
0.41
0.0
2.3
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
16
0.00
0.41
0.0
3.7
—
7.8
—
0
16
(3019060) Gas panel - Arterial blood
5
34
1.50
0.41
1.8
4.9
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
17
0.00
0.41
0.0
2.4
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
17
0.00
0.41
0.0
3.6
—
1.4
—
0
17
(40768793) Breast Pathology biopsy report
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
(3007566) Smooth muscle Ab [Titer] in Serum
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
10
132
0.72
0.36
2.9
2.2
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
26
223
1.26
0.35
1.8
1.9
pmol/l
97.0
93.0
0.18
12
116
(40761536) Microorganisms panel - Urine sediment
6
45
1.36
0.35
4.7
4.2
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
10
74
1.41
0.34
1.5
2.2
ug/g
228.0
198.1
—
5
51
(3044640) Blood type and Crossmatch panel - Blood
14
173
0.76
0.33
2.5
2.2
—
—
—
0
0
(3022145) Colonoscopy Study observation
7
55
1.30
0.31
1.1
1.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
25
219
1.22
0.27
2.4
1.9
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
60
624
0.77
0.26
15.1
14.7
umol/l
79.3
74.8
0.56
60
624
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
60
573
1.28
0.26
4.6
4.3
mmol/l
4.8
4.6
0.47
53
533
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
56
586
0.80
0.25
13.2
13.2
mg/l
14.4
20.7
1.62
45
448
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
56
533
1.23
0.24
5.7
5.0
mu/l
1.8
1.9
0.05
51
484
(3011397) Hemoglobin [Presence] in Urine by Test strip
10
123
0.78
0.22
4.5
3.1
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
10
80
1.29
0.22
1.7
1.5
%
1.4
1.4
—
10
69
(3013512) EKG study
20
175
1.20
0.21
3.8
4.2
—
—
—
0
0
(4306422)
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(4268621)
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
0
10
0.00
0.21
0.0
4.3
—
5.0
—
0
10
(3021901) Oxygen saturation in Capillary blood
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
0
10
0.00
0.21
0.0
4.3
—
8.8
—
0
10
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(40767503) Oxygen content in Capillary blood by calculation
0
12
0.00
0.21
0.0
2.9
—
16.4
—
0
6
(3005033) Fetal Nuchal fold Thickness US
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
2.6
—
18.6
—
0
12
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
13
0.00
0.21
0.0
3.4
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
13
0.00
0.21
0.0
3.4
—
4.0
—
0
13
(3035285) Chloride [Moles/volume] in Venous blood
0
13
0.00
0.21
0.0
3.4
—
105.8
—
0
13
(3000492) Spirometry study
6
48
1.27
0.21
1.3
1.3
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
22
246
0.85
0.20
9.5
9.1
e9/l
0.0
0.0
0.00
16
203
(40758558) Short blood count panel - Blood
17
147
1.20
0.20
3.1
7.6
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
0
14
0.00
0.20
0.0
1.8
—
25.2
—
0
9
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
14
0.00
0.20
0.0
1.4
—
5.8
—
0
8
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
61
588
1.24
0.20
5.5
4.7
mmol/l
2.8
2.7
0.26
54
542
(40761511) CBC panel - Blood by Automated count
60
619
0.82
0.18
10.7
11.9
—
—
—
0
0
(3002256) Pathology report gross observation
7
62
1.14
0.18
1.3
1.2
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
13
111
1.21
0.17
2.0
1.5
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
6
76
0.77
0.16
5.0
2.2
g/l
2.6
2.4
—
6
65
(3042936) Bacteria identified in Isolate by Culture
6
77
0.76
0.16
2.8
1.7
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
55
529
1.17
0.16
13.1
13.0
%
39.8
39.9
0.03
36
391
(3023368) Bacteria identified in Blood by Culture
12
139
0.84
0.16
3.7
4.2
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
97
0.80
0.15
1.8
1.8
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
21
230
0.88
0.14
5.3
3.9
ng/l
23.9
25.1
0.04
12
167
(40760892) CBC W Ordered Manual Differential panel - Blood
12
137
0.85
0.13
6.3
6.1
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
28
261
1.12
0.12
5.5
6.5
mmol/l
1.2
1.2
0.87
23
220
(3041096) Erythrocytes [Presence] in Urine by Automated
18
165
1.12
0.10
2.8
3.8
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
56
546
1.12
0.08
4.3
3.9
mmol/l
1.4
1.3
0.74
49
508
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
5
64
0.77
0.08
1.6
1.6
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
7
65
1.09
0.08
6.9
7.7
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
6
70
0.84
0.08
1.3
1.4
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
58
567
1.12
0.08
4.7
4.3
mmol/l
1.5
1.5
0.05
51
522
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
74
0.79
0.08
2.2
2.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
8
77
1.04
0.07
2.8
2.6
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
38
394
0.92
0.07
3.8
4.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
21
197
1.09
0.07
2.0
3.4
e6/l
9.7
51.5
1.24
16
134
(3044889) 12 lead EKG panel
40
387
1.08
0.06
4.9
3.7
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
58
569
1.10
0.06
5.8
4.4
mmol/l
6.1
5.9
0.36
53
526
(3026008) Bacteria identified in Urine by Culture
19
179
1.08
0.05
2.9
3.0
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
19
201
0.93
0.05
2.1
2.9
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
53
540
0.93
0.04
11.2
12.0
ml/min/173m2
81.9
83.9
0.27
41
445
(1761868) Lipid panel - Serum or Plasma
21
200
1.07
0.04
2.4
3.0
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
14
149
0.93
0.04
1.6
2.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
13
128
1.02
0.00
1.2
1.7
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
23
229
1.01
0.00
3.9
3.9
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
12
116
1.04
0.00
1.3
1.4
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
11
109
1.01
0.00
1.5
1.6
pmol/l
309.5
472.6
—
6
91
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3009466) Valproate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
6.0
—
353.8
—
0
5
(3006571) Polymorphonuclear cells/100 leukocytes in Synovial fluid
0
5
0.00
0.00
0.0
1.4
—
31.4
—
0
5
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3014133) Dog dander IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40757494) Bilirubin.total [Moles/volume] in Blood
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3045716) Anion gap in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
8.2
—
0
5
(3014051) Protein [Presence] in Urine by Test strip
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
5.0
—
215.9
—
0
5
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3019420) Tryptase [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
5.9
—
0
5
(3004616) Nuclear Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
341.5
—
0
5
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
0.3
—
0
5
(1616796) Gas panel - Central venous blood
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
53
0.94
0.00
1.8
2.0
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
5
0.00
0.00
0.0
1.4
—
31.0
—
0
5
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
5
54
0.92
0.00
1.4
1.4
g/l
10.4
10.0
—
5
49
(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
14.9
—
0
6
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
9
94
0.95
0.00
1.2
1.6
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
6
60
1.00
0.00
2.3
1.6
nmol/l
435.5
382.0
—
6
52
(3026725) Estradiol (E2) [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.5
—
0.3
—
0
8
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
7
0.00
0.00
0.0
4.0
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
0
6
0.00
0.00
0.0
3.3
—
90.9
—
0
6
(4027681)
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
7
71
0.98
0.00
1.0
1.5
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
6
0.00
0.00
0.0
6.0
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
6
65
0.92
0.00
1.3
1.2
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
5
58
0.85
0.00
3.6
3.2
umol/l
3.1
13.0
—
5
53
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(4281824)
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
25.7
—
0
6
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
39.3
—
0
6
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H8_TYMPSCLE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H8_TYMPSCLE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: H8_TYMPSCLE – Tympanosclerosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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