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Other disorders following mastoidectomy

DOID EFO Endpoint Browser PheWeb

H8_POSTMASTNAS

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H95.1
  • Cause of death: ICD-10 — H95.1

2 out of 7 registries used, show all original rules.

136

4. Check minimum number of events

None

136

5. Include endpoints

None

136

6. Filter based on genotype QC (FinnGen only)

136

Control definitions (FinnGen only)

Control exclude
H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H95
Name in latin
Aliae morbositates post operationem auris mediae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1322 658 658
Only index persons 1256 626 630
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 65.04 68.12 61.92
Only index persons 64.61 67.69 61.56

-FinnGen-

Key figures

All Female Male
Number of individuals 136 67 69
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 62.43 61.70 63.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
118
Matched controls
1180
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
170.3
118
*
UDC00
NOMESCO Finland
Ear microscopy
196.5
91.4
88
17
H71
ICD-10 Finland
Cholesteatoma of middle ear
685.7
71.9
64
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
123.7
39.8
41
5
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
+∞
36.3
33
*
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
27.1
25
*
DFF00
NOMESCO Finland
Pure tone audiometry
27.0
25.4
35
18
Z01.1
ICD-10 Finland
Examination of ears and hearing
12.6
21.2
40
46
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
+∞
19.3
18
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
25.2
18.8
26
13
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
+∞
18.2
17
*
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
210.1
18.0
18
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
17.1
16
*
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
98.4
16.0
17
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
+∞
16.0
15
*
Z97.4
ICD-10 Finland
Presence of external hearing-aid
26.4
14.8
20
9
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
61.0
14.2
16
*
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
84.8
13.9
15
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
24.8
13.8
19
9
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
+∞
13.8
13
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
157.2
13.8
14
*
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
78.5
12.9
14
*
DAX08
NOMESCO Finland
Fitting of hearing aid
28.0
12.9
17
7
TDA90
NOMESCO Finland
Removal wax from ear
144.6
12.7
13
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
34.0
12.0
15
5
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
72.3
11.9
13
*
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
132.3
11.6
12
*
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
132.3
11.6
12
*
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
+∞
11.6
11
*
Z97.8
ICD-10 Finland
Presence of other specified devices
+∞
11.6
11
*
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
14.9
11.1
18
14
DFF15
NOMESCO Finland
Speech audiometry
21.2
10.6
15
8
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
10.6
10
*
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
+∞
10.6
10
*
WX704
NOMESCO Finland
Intubation
7.3
10.2
25
42
H66.0
ICD-10 Finland
Acute suppurative otitis media
8.2
9.9
22
32
S02CA02
ATC
flumetasone and antiinfectives; otic
8.2
9.9
22
32
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
9.5
9
*
Z01.8
ICD-10 Finland
Other specified special examinations
4.0
9.2
43
149
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
20.6
9.2
13
7
H66.9
ICD-10 Finland
Otitis media, unspecified
9.4
9.0
18
22
H65.2
ICD-10 Finland
Chronic serous otitis media
54.1
8.8
10
*
H93.1
ICD-10 Finland
Tinnitus
22.0
8.7
12
6
DCD00
NOMESCO Finland
Myringoplasty
85.1
7.5
8
*
DEA10
NOMESCO Finland
Attico-antrotomy
85.1
7.5
8
*
WX725
NOMESCO Finland
Noninvasive ventilation
8.9
7.4
15
19
H69.0
ICD-10 Finland
Patulous Eustachian tube
+∞
7.4
7
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.9
7.1
65
352
WX720
NOMESCO Finland
Own respiration
8.7
6.8
14
18
H60.9
ICD-10 Finland
Otitis externa, unspecified
6.9
6.7
16
26
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
13.3
6.7
11
9
DC1AD
NOMESCO Finland
Temporalbone CT
73.6
6.5
7
*
H65.0
ICD-10 Finland
Acute serous otitis media
28.3
6.3
8
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
28.3
6.3
8
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
+∞
6.3
6
*
4151
FHL
Reoperation for chronic otitis media
+∞
6.3
6
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
6.3
6
*
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
+∞
6.3
6
*
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
+∞
6.3
6
*
-31
ICPC
Medical examin/health eval partial
4.9
6.1
19
44

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3007853) Bacteria identified in Skin by Aerobe culture
39
119
4.19
11.79
1.7
1.8
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
22
59
4.26
7.71
6.6
7.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
31
125
2.92
5.80
1.5
1.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
25
89
3.22
5.78
4.8
3.2
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
32
133
2.84
5.66
2.4
1.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
31
127
2.87
5.63
2.9
1.6
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
8
270
0.25
4.85
2.4
3.9
%
98.5
85.4
—
8
264
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
38
189
2.40
4.63
2.7
1.7
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
8
8
10.53
4.58
2.0
2.5
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
21
428
0.40
3.82
2.5
3.2
—
—
—
0
0
(40758558) Short blood count panel - Blood
12
291
0.36
3.12
2.5
6.6
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
53
343
1.89
3.11
3.2
3.1
mmol/l
7.2
7.4
0.11
45
288
(3012516) Albumin [Mass/volume] in Urine
52
336
1.89
3.06
3.3
3.2
mg/l
22.4
101.6
2.25
23
233
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
27
139
2.18
2.96
4.6
4.7
%
29.5
33.4
1.44
17
76
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
83
1010
0.54
2.89
11.3
15.3
ml/min/173m2
75.4
75.9
0.06
63
839
(3020682) Albumin/Creatinine [Ratio] in Urine
54
360
1.83
2.85
3.7
3.9
mg/mmol
3.4
16.7
2.44
26
232
(3009542) Hematocrit [Volume Fraction] of Blood
110
919
2.03
2.71
21.7
17.3
%
39.1
39.5
0.11
57
611
(3003396) Base excess in Arterial blood by calculation
27
145
2.08
2.66
5.7
6.0
mmol/l
3.4
1.3
1.76
18
116
(36304419) Bacteria [Presence] in Urine
16
322
0.43
2.65
2.9
3.0
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
84
661
1.71
2.34
2.8
2.9
u/l
48.1
48.0
0.01
74
607
(3018095) Leukocytes [#/volume] in Urine
26
420
0.53
2.24
3.1
3.7
e6/l
15.2
98.8
2.23
15
305
(3037467) Urinalysis macro (dipstick) panel - Urine
91
739
1.70
2.19
5.8
4.4
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
7
20
3.63
2.08
1.3
1.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
62
464
1.62
2.00
2.1
2.1
pmol/l
89.1
91.5
0.17
36
234
(3032080) INR in Blood by Coagulation assay
64
485
1.60
1.95
7.4
9.2
inr
1.6
1.3
0.48
13
148
(3020891) Body temperature
0
47
0.00
1.74
0.0
3.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
121
1098
1.92
1.60
21.8
14.6
—
—
—
0
0
(3043409) Potassium [Moles/volume] in Arterial blood
0
44
0.00
1.54
0.0
2.6
—
4.0
—
0
39
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
16
87
1.95
1.53
1.4
1.5
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
21
327
0.58
1.51
2.1
3.4
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
86
724
1.51
1.49
5.1
4.6
—
654.0
—
0
16
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
9
38
2.46
1.49
4.2
2.1
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
7
29
2.49
1.41
2.4
2.1
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
13
228
0.52
1.40
3.8
5.2
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
114
1028
1.67
1.39
5.4
4.8
mmol/l
5.9
6.1
1.04
105
917
(3044640) Blood type and Crossmatch panel - Blood
23
342
0.61
1.37
1.8
2.4
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
38
0.00
1.36
0.0
6.1
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
0
37
0.00
1.36
0.0
3.2
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
110
985
1.61
1.36
4.7
4.7
mu/l
2.0
2.0
0.23
98
866
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
8
36
2.30
1.26
1.1
1.0
—
—
—
0
0
(3022313) Gas panel - Capillary blood
10
49
2.12
1.25
2.0
3.8
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
28
386
0.65
1.18
2.3
3.1
mmol/l
2.3
2.4
0.33
23
341
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
7
136
0.49
1.17
2.0
3.5
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
5
20
2.55
1.16
1.2
1.1
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
63
519
1.40
1.11
5.1
5.3
mmol/l
1.2
1.2
0.04
57
470
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
8
149
0.51
1.11
4.7
3.9
u/l
371.1
245.6
—
8
140
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
90
788
1.42
1.11
3.3
3.8
pmol/l
15.0
14.9
0.27
81
686
(3007164) IgA [Mass/volume] in Serum or Plasma
12
200
0.56
1.09
1.3
1.5
g/l
2.9
2.6
—
6
117
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
109
992
1.50
1.06
6.2
6.3
mmol/mol
39.4
40.8
1.04
99
908
(3021447) Carbon dioxide [Partial pressure] in Venous blood
6
117
0.49
0.99
1.5
4.5
kpa
5.5
5.8
—
6
110
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
29
0.00
0.99
0.0
1.2
—
—
—
0
0
(3050449) Albumin [Mass/time] in Urine collected for unspecified duration
0
30
0.00
0.98
0.0
2.9
—
119.3
—
0
18
(3051387) C reactive protein [Mass/volume] in Capillary blood
0
30
0.00
0.98
0.0
4.9
—
37.4
—
0
18
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
17
251
0.63
0.97
1.8
2.2
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
89
789
1.37
0.95
5.3
4.1
mm/h
13.4
14.0
0.12
81
715
(3019225) pH of Specimen
16
104
1.61
0.89
3.4
3.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
12
72
1.73
0.88
1.4
1.2
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
55
457
1.34
0.88
2.1
2.2
nmol/l
83.5
76.8
1.10
50
386
(4035726)
6
114
0.50
0.87
1.7
1.4
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
6
31
1.98
0.85
1.3
1.6
—
0.1
—
0
8
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
18
122
1.55
0.85
1.1
1.4
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
24
0.00
0.80
0.0
1.4
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
24
0.00
0.80
0.0
1.3
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
0
24
0.00
0.80
0.0
1.4
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
0
24
0.00
0.80
0.0
1.4
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
24
0.00
0.80
0.0
1.8
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
26
0.00
0.79
0.0
1.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
66
570
1.31
0.79
3.2
2.6
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
42
340
1.34
0.79
3.4
4.3
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
14
91
1.60
0.79
2.1
1.5
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
19
262
0.68
0.79
1.2
1.4
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
76
670
1.30
0.78
5.1
4.4
mmol/l
6.9
6.7
0.43
69
635
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
66
573
1.29
0.75
7.8
5.9
mmol/l
1.2
1.2
0.74
61
481
(46235355) HIV 1 and 2 tests - Meaningful Use set
10
157
0.61
0.74
1.7
1.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
22
161
1.44
0.74
1.9
1.7
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
110
1026
1.38
0.72
4.5
4.6
mmol/l
4.5
4.5
0.12
100
927
(3012544) pH of Venous blood
7
117
0.58
0.72
1.4
4.4
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
32
253
1.35
0.70
1.4
1.9
pmol/l
373.7
417.8
0.72
27
213
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
8
127
0.61
0.68
1.9
1.4
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
29
227
1.35
0.67
4.0
4.3
kg/l
1.0
1.0
—
10
32
(3017143) Hepatitis C virus Ab [Presence] in Serum
6
104
0.56
0.65
1.3
1.4
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
45
378
1.28
0.64
3.0
3.3
ng/l
2009.3
1638.8
0.17
38
322
(3026008) Bacteria identified in Urine by Culture
43
360
1.28
0.63
3.5
3.5
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
20
0.00
0.61
0.0
1.4
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
112
1056
1.34
0.61
5.4
5.2
mmol/l
2.6
2.6
0.16
101
942
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
22
0.00
0.60
0.0
1.4
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
22
0.00
0.60
0.0
1.2
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
8
53
1.54
0.59
2.4
2.3
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
0
23
0.00
0.59
0.0
3.8
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
23
0.00
0.59
0.0
1.4
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
23
0.00
0.59
0.0
2.7
—
106.9
—
0
23
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
23
0.00
0.59
0.0
2.7
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
23
0.00
0.59
0.0
1.4
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
23
0.00
0.59
0.0
2.7
—
4.1
—
0
23
(3011397) Hemoglobin [Presence] in Urine by Test strip
18
235
0.73
0.55
3.8
4.1
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
9
62
1.48
0.54
1.0
1.4
—
—
—
0
0
(40768443) Skin Pathology biopsy report
6
39
1.56
0.53
1.0
1.3
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
118
1127
1.36
0.52
10.4
10.5
u/l
24.2
24.4
0.07
109
1084
(3019309) Folate [Moles/volume] in Red Blood Cells
29
236
1.29
0.52
1.4
1.8
nmol/l
803.7
1193.8
2.81
22
180
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
34
402
0.79
0.51
3.4
4.2
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
54
478
1.22
0.48
2.9
4.4
ng/l
27.3
52.7
1.46
31
373
(3002256) Pathology report gross observation
9
126
0.69
0.46
1.3
1.3
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
11
150
0.71
0.44
1.5
1.2
—
14.8
—
0
57
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
12
161
0.72
0.44
1.3
1.2
iu/ml
12.8
45.6
—
6
55
(40761535) Cells panel - Urine sediment
6
93
0.63
0.44
3.3
3.9
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
24
290
0.79
0.43
2.5
3.6
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
29
243
1.25
0.42
1.7
1.8
mg/l
1.7
1.3
0.30
22
191
(3011288) Drugs identified in Urine by Screen method
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
(4281824)
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
0
16
0.00
0.41
0.0
4.3
—
65.8
—
0
16
(3030905) Polymorphonuclear cells [#/volume] in Blood
0
18
0.00
0.40
0.0
3.4
—
4.4
—
0
18
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
18
0.00
0.40
0.0
3.3
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
0
19
0.00
0.39
0.0
4.4
—
58.1
—
0
19
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
9
67
1.37
0.39
2.3
1.7
—
—
—
0
0
(3009343) pH of Capillary blood
11
81
1.39
0.37
2.2
3.6
—
7.4
—
0
12
(3003458) Phosphate [Moles/volume] in Serum or Plasma
13
167
0.76
0.37
5.4
4.3
mmol/l
1.2
1.0
1.38
13
150
(3005719) IgG [Mass/volume] in Serum or Plasma
5
80
0.61
0.36
2.0
2.6
g/l
9.9
9.9
—
5
72
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
111
1069
1.21
0.32
18.9
15.6
mg/l
23.0
25.3
0.35
92
880
(3022145) Colonoscopy Study observation
9
116
0.76
0.29
1.0
1.3
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
45
412
1.14
0.25
4.0
5.4
ug/l
13.0
2.3
0.50
36
354
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
53
492
1.13
0.24
4.5
4.0
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
38
1.33
0.23
1.6
1.1
—
—
—
0
0
(4010399)
11
88
1.27
0.23
1.5
1.4
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
5
39
1.29
0.23
3.2
2.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
5
39
1.29
0.23
2.2
2.5
u/ml
0.2
0.3
—
5
20
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
105
1017
1.14
0.22
4.7
4.6
mmol/l
1.4
1.5
0.99
95
905
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(4306422)
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
11
0.00
0.21
0.0
1.4
—
6.3
—
0
6
(3044242) Glucose [Moles/volume] in Arterial blood
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3019420) Tryptase [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.0
—
5.3
—
0
10
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
13
0.00
0.21
0.0
1.1
—
201.0
—
0
13
(3051611) Lipemic interference index of Serum or Plasma
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
(3004775) Volume in Urine collected for unspecified duration
0
13
0.00
0.21
0.0
2.9
—
477.6
—
0
7
(3022217) INR in Platelet poor plasma by Coagulation assay
16
186
0.84
0.20
16.8
26.5
—
1.3
—
0
24
(40768804) Tissue Pathology biopsy report
39
423
0.89
0.20
2.5
2.2
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
77
0.77
0.16
1.0
1.9
—
—
—
0
0
(3022621) pH of Urine by Test strip
6
79
0.75
0.16
2.8
2.5
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
88
852
1.09
0.15
6.6
7.1
u/l
72.1
79.6
1.62
82
791
(42870588) Differential panel, method unspecified - Blood
38
355
1.10
0.14
4.8
5.2
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
12
103
1.18
0.14
3.5
3.6
ng/l
85.8
91.4
0.12
12
90
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
12
135
0.88
0.10
8.0
9.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
43
1.17
0.10
1.0
1.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
46
1.09
0.09
1.6
2.1
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
48
500
0.94
0.09
6.4
4.0
g/l
34.8
35.0
0.12
42
469
(3019832) Treponema pallidum Ab [Presence] in Serum
5
62
0.80
0.08
2.0
1.5
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
70
0.85
0.08
1.0
1.7
—
—
—
0
0
(3000492) Spirometry study
9
85
1.06
0.07
2.0
1.5
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
8
91
0.87
0.07
1.3
2.1
g/l
0.2
0.2
—
8
82
(40768797) Stomach Pathology biopsy report
16
150
1.08
0.04
1.2
1.3
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
31
320
0.96
0.03
4.6
4.8
%
24.6
20.5
0.47
13
158
(3044889) 12 lead EKG panel
75
760
0.97
0.03
4.9
4.1
—
—
—
0
0
(3013512) EKG study
34
347
0.97
0.01
4.4
4.4
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
13
126
1.04
0.00
1.2
1.5
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
99
992
0.99
0.00
3.7
4.1
mmol/l
1.3
1.3
0.13
89
878
(3037556) Urate [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013727) Leukocytes other/100 leukocytes in Blood
0
6
0.00
0.00
0.0
5.5
—
50.2
—
0
6
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
23.8
—
0
6
(40768441) Liver Pathology biopsy report
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012565) Volume of 24 hour Urine
0
6
0.00
0.00
0.0
2.8
—
2365.8
—
0
6
(3024474) Albumin [Mass/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
275.0
—
0
6
(3016244) Insulin [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
12.1
—
0
6
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4027681)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3035880) pH of Pleural fluid
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
9
0.00
0.00
0.0
4.3
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
7
0.00
0.00
0.0
13.4
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3020876) Protein [Mass/time] in 24 hour Urine
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3006442) Creatine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
11.8
—
0
7
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
62
0.97
0.00
1.2
1.9
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
9
0.00
0.00
0.0
2.0
—
9.8
—
0
9
(3051651) Icteric interference index of Serum or Plasma
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(44813793)
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3047189) Immunofixation for 24 hour Urine
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3017315) Amylase [Enzymatic activity/volume] in Urine
0
5
0.00
0.00
0.0
1.4
—
125.2
—
0
5
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3034988) Calcium [Moles/volume] in Capillary blood
0
5
0.00
0.00
0.0
2.2
—
1.2
—
0
5
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(44806420)
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
5.6
—
—
—
0
0
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.0
—
106.2
—
0
5
(3032773) Endomysium IgG Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014891) Appearance of Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3020073) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Specimen
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
6
61
0.98
0.00
1.5
1.4
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
9
0.00
0.00
0.0
2.8
—
—
—
0
0
(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
2.9
—
237.9
—
0
7
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H8_POSTMASTNAS and mortality.

Females

Parameter HR [95% CI] p-value
H8_POSTMASTNAS 1.322 [1.09, 1.61] 0.006
Birth year 0.994 [0.99, 1.0] 0.194

During the follow-up period (1.1.1998 — 31.12.2019), 152 out of 602 females with H8_POSTMASTNAS died.

Males

Parameter HR [95% CI] p-value
H8_POSTMASTNAS 1.037 [0.84, 1.29] 0.741
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 142 out of 605 males with H8_POSTMASTNAS died.

Mortality risk

Mortality risk for people of age

years, who have H8_POSTMASTNAS.

N-year risk Females Males
1 0.151% 0.198%
5 0.789% 1.264%
10 1.944% 2.977%
15 3.714% 5.379%
20 6.312% 9.286%

Relationships between endpoints

↥

Index endpoint: H8_POSTMASTNAS – Other disorders following mastoidectomy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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