Petrositis

H8_PETROS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H70.2 Cause of death: ICD-10 — H70.2 2 out of 7 registries used, show all original rules.	7
4. Check minimum number of events None	7
5. Include endpoints None	7
6. Filter based on genotype QC (FinnGen only)	7

Control definitions (FinnGen only)

Control exclude: H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H70
Name in latin: Petrositis

NAME	H8_PETROS
CONTROL_EXCLUDE	H8_MIDDLEMASTOID
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H702
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H702
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Petrositis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

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FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	89	41	48
Only index persons	83	37	46
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	54.97	56.79
Only index persons	54.39	51.82	56.46

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	7	-	-
Unadjusted period prevalence (%)	0.00	-	-
Median age at first event (years)	59.18	-	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

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(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3044889) 12 lead EKG panel

+∞

1.75

6.7

4.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

+∞

1.04

2.6

4.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

+∞

0.48

14.4

ml/min/173m2

72.3

74.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.23

0.0

1.8

—

(3019225) pH of Specimen

0.00

0.23

0.0

2.2

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

+∞

0.23

22.4

18.3

umol/l

87.4

81.8

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.00

0.23

0.0

4.3

—

26.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

0.00

0.23

0.0

2.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.00

0.23

0.0

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.23

0.0

4.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.23

0.0

3.9

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

+∞

0.23

5.7

5.0

mmol/l

5.6

6.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

+∞

0.23

15.7

13.8

mg/l

10.0

25.1

—

(3024731) MCV [Entitic volume]

+∞

0.00

29.7

20.2

95.6

91.4

—

(3035941) MCH [Entitic mass]

+∞

0.00

29.6

20.1

31.4

30.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3000963) Hemoglobin [Mass/volume] in Blood

+∞

0.00

29.7

20.3

g/l

128.6

136.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

0.0

1.7

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.00

0.0

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.00

0.0

1.4

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.0

1.2

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

38.8

—

(3022145) Colonoscopy Study observation

0.00

0.0

1.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.00

0.0

1.0

—

(40761511) CBC panel - Blood by Automated count

+∞

0.00

13.1

11.3

—

(3022621) pH of Urine by Test strip

0.00

0.0

2.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint H8_PETROS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H8_PETROS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

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Index endpoint: H8_PETROS – Petrositis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

Extremity

rg [CI]

Extremity

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Petrositis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints