info icon

This is a non-core endpoint: only basic statistics are computed.

Otitis media in diseases classified elsewhere

H8_OTIMEDINOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H67*
  • Cause of death: ICD-10 H67*

2 out of 7 registries used, show all original rules.

30

4. Check minimum number of events

None

30

5. Include endpoints

None

30

6. Filter based on genotype QC (FinnGen only)

30

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 529 245 283
Only index persons 340 165 175
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 5.02 5.76 4.27
Only index persons 10.65 13.98 7.52

-FinnGen-

Key figures

All Female Male
Number of individuals 30 18 12
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 46.93 30.05 72.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
10
13
11.04
7.60
2.2
1.5
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
15
41
6.32
5.80
2.5
1.9
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
11
23
6.97
5.51
2.7
1.4
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
11
25
6.37
5.04
2.9
1.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
14
58
3.65
2.90
12.9
5.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
17
82
3.48
2.76
9.9
11.6
inr
1.0
1.3
—
5
35
(3024891) Influenza virus A+B Ag [Presence] in Specimen
6
11
6.50
2.68
1.0
1.2
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
9
27
4.30
2.66
2.3
2.5
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
9
28
4.14
2.57
1.1
1.6
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
25
165
4.08
2.51
6.8
4.6
—
21.6
—
0
5
(3002173) Hemoglobin [Mass/volume] in Arterial blood
6
15
4.71
2.16
8.3
13.8
g/l
124.8
119.9
—
6
15
(42870588) Differential panel, method unspecified - Blood
14
68
2.99
2.13
5.7
5.0
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
6
16
4.41
2.05
6.2
4.3
ng/l
101.2
91.0
—
6
16
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
17
94
2.87
2.03
17.9
6.3
mmol/l
1.2
1.2
0.12
17
89
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
11
5.21
2.02
2.0
1.7
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
11
5.21
2.02
1.4
1.1
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
11
5.21
2.02
1.4
1.1
—
—
—
0
0
(40758558) Short blood count panel - Blood
13
63
2.88
1.96
17.8
5.8
—
—
—
0
0
(3002256) Pathology report gross observation
6
22
3.14
1.52
1.3
1.3
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
24
180
2.66
1.50
6.0
3.5
mm/h
21.2
11.1
0.87
24
168
(3012544) pH of Venous blood
8
34
2.83
1.42
14.8
3.9
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
17
108
2.32
1.37
6.1
4.2
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
11
62
2.22
1.13
1.9
1.7
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
17
115
2.10
1.10
15.2
5.8
umol/l
10.3
9.8
0.13
17
109
(46235355) HIV 1 and 2 tests - Meaningful Use set
13
80
2.10
1.07
2.0
2.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
12
73
2.07
1.01
4.3
3.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
12
73
2.07
1.01
1.3
1.7
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
8
44
2.11
0.96
3.1
2.4
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
8
45
2.06
0.94
1.5
1.8
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
9
52
2.04
0.87
2.0
4.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
11
68
1.98
0.86
4.0
2.5
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
14
95
1.89
0.84
5.5
3.2
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
5
23
2.40
0.80
16.2
2.3
umol/l
8.0
13.9
—
5
18
(3021879) Hepatitis B virus core Ab [Presence] in Serum
5
26
2.10
0.74
2.0
1.3
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
18
139
1.74
0.67
18.8
5.0
mmol/l
6.1
6.3
0.19
18
124
(3015736) pH of Urine
7
104
0.57
0.64
4.0
3.7
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
17
131
1.69
0.62
2.9
2.5
ug/l
78.0
79.2
0.02
17
118
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
7
99
0.62
0.50
4.0
4.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
8
56
1.58
0.48
3.8
3.6
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
5
33
1.62
0.44
1.0
2.5
g/l
2.7
2.4
—
5
27
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
9
68
1.46
0.43
2.2
2.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
15
0.00
0.42
0.0
1.6
—
—
—
0
0
(4010399)
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
5
74
0.61
0.42
2.2
4.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
17
0.00
0.42
0.0
1.1
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
18
0.00
0.41
0.0
1.1
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
10
74
1.53
0.38
1.5
2.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
11
84
1.49
0.37
4.8
3.1
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
20
174
1.45
0.33
4.3
4.0
pmol/l
14.4
14.4
0.00
20
153
(3044889) 12 lead EKG panel
17
144
1.42
0.32
4.1
3.4
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
16
136
1.38
0.29
8.6
2.6
u/l
45.1
34.4
0.48
16
129
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
22
198
1.42
0.27
3.7
3.7
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
11
0.00
0.22
0.0
5.2
—
1.3
—
0
11
(3038515) Glucose [Moles/volume] in Venous blood
0
11
0.00
0.22
0.0
5.2
—
6.9
—
0
11
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
10
0.00
0.22
0.0
4.2
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
10
0.00
0.22
0.0
4.2
—
3.9
—
0
10
(3035285) Chloride [Moles/volume] in Venous blood
0
10
0.00
0.22
0.0
4.2
—
107.6
—
0
10
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
10
0.00
0.22
0.0
1.6
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
13
0.00
0.21
0.0
6.0
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
8
66
1.29
0.19
3.5
2.5
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
8
69
1.22
0.18
3.4
2.6
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
5
43
1.19
0.11
2.6
1.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
6
53
1.16
0.10
2.0
1.8
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3011412) CD3 cells [#/volume] in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
0
6
0.00
0.00
0.0
2.0
—
1.6
—
0
6
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
5
50
1.00
0.00
1.2
1.5
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
62.0
—
0
8
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(1002224) Polysomnography panel
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
0
5
0.00
0.00
0.0
1.4
—
90.4
—
0
5
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_OTIMEDINOTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H8_OTIMEDINOTH.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: H8_OTIMEDINOTH – Otitis media in diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data