Otitis media: Inflammation of the anatomical structures of the middle ear, which is most often caused by an infectious process. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever.
Other specified/unspecified disorders of middle ear and mastoid
DOID EFO Endpoint Browser PheWeb
H8_MIDDMASTNAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
82 |
4. Check minimum number of eventsNone |
82 |
5. Include endpointsNone |
82 |
6. Filter based on genotype QC (FinnGen only) |
82 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified/unspecified disorders of middle ear and mastoid
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 788 | 397 | 384 |
| Only index persons | 681 | 343 | 338 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 49.36 | 49.06 | 49.54 |
| Only index persons | 49.00 | 48.89 | 49.11 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 82 | 54 | 28 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 52.59 | 49.96 | 57.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 75
- Matched controls
- 749
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H74.9
ICD-10 Finland
Disorder of middle ear and mastoid, unspecified
+∞
30.2
27
*
H74.8
ICD-10 Finland
Other specified disorders of middle ear and mastoid
+∞
27.8
25
*
3858X
ICD-9 Finland
Other disorders of middle ear and mastoid
+∞
18.5
17
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
11.2
15.2
31
44
UDC00
NOMESCO Finland
Ear microscopy
17.0
14.9
24
20
H65.2
ICD-10 Finland
Chronic serous otitis media
+∞
10.7
10
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
63.3
9.9
11
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
21.0
9.8
14
8
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
9.6
9
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
+∞
9.6
9
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
56.7
8.9
10
*
DFF00
NOMESCO Finland
Pure tone audiometry
9.1
8.6
18
25
H66.9
ICD-10 Finland
Otitis media, unspecified
12.7
7.1
12
11
H60.3
ICD-10 Finland
Other infective otitis externa
18.9
6.9
10
6
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
44.0
6.9
8
*
3859X
ICD-9 Finland
Other disorders of middle ear and mastoid, Unspecified disorder of middle ear and mastoid
+∞
6.3
6
*
DC1AD
NOMESCO Finland
Temporalbone CT
+∞
6.3
6
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3007853) Bacteria identified in Skin by Aerobe culture
19
81
2.75
3.28
3.9
1.6
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
17
79
2.45
2.45
1.5
1.4
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
8
6.56
2.40
1.0
1.0
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
15
69
2.43
2.20
1.3
1.4
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
27
160
2.02
2.17
1.3
2.0
mg/l
2.0
1.2
0.35
20
129
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
5
10
5.24
2.10
8.6
3.2
%
51.4
60.2
—
5
10
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
23
130
2.07
2.09
1.7
1.9
pmol/l
366667066.2
453.3
0.48
18
106
(3027273) Bicarbonate [Moles/volume] in Venous blood
9
32
3.03
2.07
3.7
5.1
mmol/l
24.0
24.3
—
9
32
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
9
32
3.03
2.07
4.9
5.1
%
45.0
47.3
—
9
32
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
21
115
2.11
2.07
1.4
1.3
iu/ml
31.9
43.7
—
6
36
(3020891) Body temperature
7
24
3.09
1.76
3.4
5.2
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
13
65
2.19
1.58
1.7
1.6
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
11
51
2.33
1.58
3.0
5.8
kpa
4.3
4.2
0.12
11
51
(3004119) Hemoglobin [Mass/volume] in Venous blood
9
38
2.53
1.51
3.1
5.6
g/l
130.4
129.9
—
9
38
(3012544) pH of Venous blood
12
60
2.17
1.46
2.9
6.9
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
13
68
2.08
1.42
1.7
1.7
—
—
—
0
0
(3002256) Pathology report gross observation
14
76
2.01
1.39
1.4
1.2
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
59
494
1.69
1.28
5.8
4.3
mm/h
12.3
12.3
0.00
53
455
(3007930) Methemoglobin/Hemoglobin.total in Blood
6
26
2.40
1.21
6.0
5.0
%
0.9
0.7
—
6
26
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
59
501
1.63
1.14
5.0
4.2
pmol/l
14.7
15.0
0.35
53
452
(3027945) Reticulocytes/100 erythrocytes in Blood
13
74
1.90
1.14
3.5
3.2
%
1.7
1.8
0.18
13
68
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
35
264
1.57
1.14
6.7
4.4
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
29
210
1.59
1.12
10.1
5.7
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
22
149
1.65
1.10
7.7
5.6
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
11
60
1.96
1.08
3.1
6.9
kpa
5.8
5.8
0.09
11
60
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
17
108
1.72
1.07
1.4
1.3
u/ml
1.7
9.6
—
8
42
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
9
47
2.02
1.06
2.9
2.0
ng/l
95.2
238.3
—
9
42
(3005719) IgG [Mass/volume] in Serum or Plasma
10
53
2.01
1.06
5.0
2.1
g/l
9.5
10.4
—
10
47
(3021601) Nitrite [Presence] in Urine by Test strip
42
334
1.52
1.06
7.7
5.7
estimate
0.0
0.0
0.00
11
57
(3035350) Ketones [Presence] in Urine by Test strip
42
334
1.52
1.06
6.3
4.1
estimate
0.0
0.0
0.00
11
63
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
15
93
1.75
1.02
1.8
1.7
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
13
77
1.82
1.02
5.1
6.6
mmol/l
1.1
1.0
0.66
13
71
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
12
71
1.81
0.94
1.4
3.3
umol/l
4.2
9.8
1.63
12
59
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
10
56
1.89
0.92
1.9
2.8
g/l
0.2
0.2
—
10
49
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
8
42
2.00
0.92
1.9
1.1
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
14
88
1.71
0.91
1.4
1.5
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
42
342
1.46
0.90
6.2
4.1
estimate
0.0
0.0
—
10
60
(3000330) Specific gravity of Urine by Test strip
8
43
1.95
0.90
3.9
4.0
—
—
—
0
0
(3019060) Gas panel - Arterial blood
8
43
1.95
0.90
3.6
5.3
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
8
43
1.95
0.90
1.1
1.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
25
184
1.51
0.88
4.5
3.9
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
11
65
1.80
0.87
3.5
3.8
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
15
98
1.65
0.85
2.7
2.2
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
6
32
1.94
0.83
2.5
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
25
186
1.49
0.83
7.5
4.4
estimate
0.0
0.0
0.00
11
58
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
5
23
2.24
0.77
2.2
2.6
—
12873.0
—
0
7
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
38
1.92
0.76
1.0
1.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
9
56
1.68
0.75
4.7
3.6
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
39
323
1.39
0.72
7.7
7.2
mmol/l
1.2
1.2
1.40
32
276
(3045414) Leukocytes [Presence] in Urine
5
28
1.83
0.67
3.0
1.5
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
32
260
1.38
0.65
2.3
1.9
pmol/l
84.6
97.7
1.19
19
124
(3032080) INR in Blood by Coagulation assay
31
251
1.38
0.64
17.1
8.7
inr
1.4
1.3
—
9
79
(40768793) Breast Pathology biopsy report
0
20
0.00
0.61
0.0
1.4
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
8
53
1.56
0.60
1.8
2.0
—
—
—
0
0
(3009214) Lutropin [Units/volume] in Serum or Plasma
0
23
0.00
0.59
0.0
1.2
—
16.1
—
0
18
(3037467) Urinalysis macro (dipstick) panel - Urine
52
464
1.33
0.54
7.4
4.6
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
6
39
1.58
0.54
2.5
9.9
%
92.2
93.2
—
6
39
(3018095) Leukocytes [#/volume] in Urine
31
258
1.32
0.53
2.9
3.6
e6/l
63.7
59.2
0.03
25
179
(3044889) 12 lead EKG panel
50
445
1.31
0.52
5.3
3.9
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
5
80
0.60
0.48
4.8
4.8
%
32.4
33.1
—
5
50
(3009542) Hematocrit [Volume Fraction] of Blood
64
593
1.36
0.48
18.8
15.6
%
40.1
39.2
0.55
37
437
(3000991) Gas panel - Venous blood
7
49
1.47
0.47
2.3
9.4
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
31
262
1.29
0.46
5.5
3.1
—
—
—
0
0
(4035726)
8
55
1.50
0.44
1.0
1.5
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
8
55
1.50
0.44
2.3
1.4
g/l
72.2
65.7
—
8
50
(36304419) Bacteria [Presence] in Urine
24
197
1.31
0.44
2.6
2.7
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
31
1.65
0.44
1.6
1.3
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
15
115
1.37
0.42
1.5
1.7
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
15
0.00
0.41
0.0
3.2
—
106.1
—
0
15
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
15
0.00
0.41
0.0
3.2
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
15
0.00
0.41
0.0
3.2
—
4.0
—
0
15
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
(4034850)
0
17
0.00
0.41
0.0
9.1
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3006184) Hemoglobin [Mass/volume] in Capillary blood
0
18
0.00
0.40
0.0
2.1
—
127.1
—
0
11
(3009508) Creatinine [Moles/volume] in Urine
24
200
1.28
0.39
1.6
2.9
mmol/l
8.1
7.4
0.23
18
161
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
19
0.00
0.39
0.0
1.7
—
6.2
—
0
12
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
5
36
1.41
0.39
2.0
3.9
%
1.7
0.9
—
5
36
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
5
36
1.41
0.39
1.2
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
22
182
1.28
0.38
1.5
1.5
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
21
173
1.29
0.37
6.8
3.6
—
—
—
0
0
(3018418) pH of Serum or Plasma
25
211
1.26
0.37
6.2
4.0
ph
7.4
7.4
—
7
43
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
16
127
1.32
0.37
1.4
1.6
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
21
174
1.28
0.36
5.7
4.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
33
290
1.23
0.34
2.6
2.0
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
12
92
1.35
0.34
1.0
1.2
—
—
—
0
0
(3003338) MCHC [Mass/volume]
60
565
1.23
0.29
27.6
19.2
g/l
331.8
331.1
0.25
60
565
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
39
426
0.84
0.29
3.3
2.9
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
22
189
1.22
0.28
1.8
2.9
mg/l
80.6
64.8
0.08
11
120
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
6
84
0.69
0.25
4.0
2.8
%
14.8
20.6
—
6
73
(3019550) Sodium [Moles/volume] in Serum or Plasma
70
673
1.27
0.25
23.3
16.1
mmol/l
139.7
139.8
0.06
70
659
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
65
621
1.22
0.24
18.1
13.7
ml/min/173m2
82.2
80.3
0.31
53
497
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
21
182
1.20
0.24
2.0
1.8
mmol/l
1.4
1.4
0.06
12
155
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
36
328
1.17
0.24
4.1
3.7
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
7
94
0.72
0.24
3.4
2.7
umol/l
10.8
12.3
—
7
84
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
10
79
1.30
0.23
17.5
8.4
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
24
213
1.18
0.21
1.8
2.0
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
2.5
—
2.7
—
0
11
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.4
—
31.8
—
0
13
(3026008) Bacteria identified in Urine by Culture
26
233
1.17
0.21
4.8
2.9
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
70
676
1.23
0.21
23.9
16.0
mmol/l
4.0
4.0
0.26
70
658
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
6
48
1.27
0.21
1.3
1.7
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(40767503) Oxygen content in Capillary blood by calculation
0
14
0.00
0.20
0.0
2.9
—
15.8
—
0
7
(3019225) pH of Specimen
6
51
1.19
0.20
3.3
3.6
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
7
62
1.14
0.18
2.3
2.8
u/l
29.3
28.8
—
7
54
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
8
71
1.14
0.16
1.7
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
21
188
1.16
0.16
8.3
7.1
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
78
0.75
0.16
2.0
2.0
—
—
—
0
0
(3022145) Colonoscopy Study observation
7
86
0.80
0.15
1.3
1.3
—
—
—
0
0
(3026361) Erythrocytes [#/volume] in Blood
75
732
1.27
0.15
32.0
21.1
e12/l
4.4
4.5
0.50
75
713
(3000963) Hemoglobin [Mass/volume] in Blood
75
732
1.27
0.15
32.1
21.2
g/l
132.4
134.6
0.64
75
721
(3007461) Platelets [#/volume] in Blood
75
732
1.27
0.15
32.0
21.1
e9/l
246.0
250.6
0.26
75
717
(3035941) MCH [Entitic mass]
75
732
1.27
0.15
31.9
21.0
pg
30.0
30.2
0.44
75
723
(3024731) MCV [Entitic volume]
75
732
1.27
0.15
31.9
21.0
fl
90.3
91.0
0.75
75
723
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
17
152
1.15
0.13
1.8
1.9
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
71
693
1.17
0.12
22.4
12.4
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
5
43
1.17
0.10
2.0
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
24
224
1.10
0.09
3.4
2.9
—
—
—
0
0
(40761535) Cells panel - Urine sediment
6
53
1.14
0.09
13.3
3.4
—
—
—
0
0
(3013512) EKG study
20
185
1.11
0.09
3.5
4.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
5
64
0.77
0.08
3.8
2.2
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
18
166
1.11
0.08
1.2
1.3
u/ml
0.7
0.8
—
8
52
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
6
72
0.82
0.08
1.8
1.5
%
1.3
1.3
—
6
64
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
74
0.79
0.08
2.0
1.9
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
10
112
0.88
0.08
1.6
1.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
65
661
0.91
0.06
22.0
14.5
mg/l
19.8
23.1
0.51
58
527
(3002385) Erythrocyte distribution width [Ratio]
58
570
1.06
0.03
26.0
17.4
%
13.8
13.6
0.26
58
561
(3020682) Albumin/Creatinine [Ratio] in Urine
21
203
1.04
0.01
2.3
3.7
mg/mmol
20.8
10.0
0.36
11
122
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
13
126
1.04
0.00
5.9
4.7
%
21.2
21.1
—
7
61
(3020564) Creatinine [Moles/volume] in Serum or Plasma
70
696
1.03
0.00
25.4
16.6
umol/l
77.5
75.6
0.16
70
696
(3000492) Spirometry study
5
53
0.94
0.00
1.0
1.5
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
5
53
0.94
0.00
2.0
2.8
e9/l
4.2
4.1
—
5
44
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(4306422)
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
9.2
—
0
5
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
0
9
0.00
0.00
0.0
2.7
—
91.5
—
0
9
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(4268621)
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3020491) Glucose [Moles/volume] in Blood
0
5
0.00
0.00
0.0
2.4
—
6.1
—
0
5
(3038026) Centromere Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
1.3
—
0
5
(3035880) pH of Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
100.3
—
0
7
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40757494) Bilirubin.total [Moles/volume] in Blood
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
21.0
—
0
8
(3045788) Cell count panel - Pleural fluid
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020876) Protein [Mass/time] in 24 hour Urine
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(4211845)
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
0.00
0.0
1.1
—
107.3
—
0
7
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_MIDDMASTNAS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MIDDMASTNAS | 1.128 [0.74, 1.72] | 0.576 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 259 males with H8_MIDDMASTNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_MIDDMASTNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.187% |
| 5 | No data | 1.065% |
| 10 | No data | 2.818% |
| 15 | No data | 5.374% |
| 20 | No data | 9.128% |
Relationships between endpoints
↥Index endpoint: H8_MIDDMASTNAS – Other specified/unspecified disorders of middle ear and mastoid
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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