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Malignant otitis externa

DOID Endpoint Browser PheWeb

H8_EXT_MALIGN

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H60.2
  • Hospital discharge: ICD-9 — 3801C
  • Cause of death: ICD-10 — H60.2
  • Cause of death: ICD-9 — 3801C

2 out of 7 registries used, show all original rules.

61

4. Check minimum number of events

None

61

5. Include endpoints

None

61

6. Filter based on genotype QC (FinnGen only)

61

Control definitions (FinnGen only)

Control exclude
H8_EXTERNAL

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H60
Name in latin
Otitis externa [maligna]

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 540 251 283
Only index persons 480 228 252
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 54.45 50.70 57.43
Only index persons 53.03 48.66 56.98

-FinnGen-

Key figures

All Female Male
Number of individuals 61 31 30
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 53.84 47.01 60.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
55
Matched controls
551
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H60.2
ICD-10 Finland
Malignant otitis externa
+∞
76.1
54
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
25.1
15.0
21
13
H60.8
ICD-10 Finland
Other otitis externa
67.2
13.6
15
*
H60.3
ICD-10 Finland
Other infective otitis externa
166.4
13.0
13
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
14.5
9.6
16
15
DC1AD
NOMESCO Finland
Temporalbone CT
92.0
7.6
8
*
H66.9
ICD-10 Finland
Otitis media, unspecified
12.4
6.9
12
12
UDC00
NOMESCO Finland
Ear microscopy
10.2
6.8
13
16
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
6.4
6
*
H60.0
ICD-10 Finland
Abscess of external ear
+∞
6.4
6
*
A46
ICD-10 Finland
Erysipelas
6.8
6.3
16
31

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3007853) Bacteria identified in Skin by Aerobe culture
25
44
8.93
15.11
3.9
2.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
20
53
5.13
7.54
3.5
1.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
15
43
4.30
4.98
4.9
1.3
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
39
216
3.23
4.65
8.3
6.0
e9/l
0.0
0.0
1.09
32
195
(3019198) Lymphocytes [#/volume] in Blood
39
222
3.10
4.33
8.3
5.9
e9/l
2.0
1.8
0.61
33
203
(3042936) Bacteria identified in Isolate by Culture
18
65
3.51
4.31
4.9
1.8
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
39
223
3.08
4.27
8.6
5.9
e9/l
0.2
0.2
0.52
34
203
(3027273) Bicarbonate [Moles/volume] in Venous blood
10
23
5.00
4.27
5.2
2.7
mmol/l
23.4
24.9
—
10
23
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
20
78
3.33
4.25
10.2
2.7
ng/l
440.9
170.6
0.30
14
55
(3001604) Monocytes [#/volume] in Blood
38
215
3.04
4.23
8.4
5.9
e9/l
0.6
0.6
0.15
33
193
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
18
66
3.45
4.20
4.5
1.8
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
27
127
3.02
4.18
8.8
5.3
—
—
—
0
0
(3019060) Gas panel - Arterial blood
10
24
4.79
4.06
10.2
4.2
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
7
8
9.68
3.88
1.7
1.6
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
28
140
2.85
3.82
4.0
3.4
mg/mmol
18.9
4.5
0.69
18
88
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
14
46
3.65
3.82
5.0
1.4
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
27
134
2.82
3.72
3.3
2.9
mg/l
61.2
38.3
0.21
18
81
(3009508) Creatinine [Moles/volume] in Urine
28
145
2.72
3.52
3.2
2.8
mmol/l
6.6
8.3
1.33
23
126
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
8
18
4.94
2.90
25.3
6.5
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
9
24
4.21
2.80
5.0
2.5
g/l
117.6
133.0
—
9
24
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
10
6.51
2.76
3.7
1.6
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
11
38
3.31
2.74
6.2
2.3
kpa
5.8
5.7
0.22
11
38
(3022948) Iron [Moles/volume] in Serum or Plasma
14
58
2.83
2.59
6.0
1.7
umol/l
11.3
14.1
1.13
14
52
(3021960) Folate [Moles/volume] in Serum or Plasma
20
100
2.49
2.58
1.8
1.6
nmol/l
15.8
20.3
0.70
15
82
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
7
16
4.79
2.55
4.7
1.9
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
12
5.41
2.46
1.8
1.4
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
27
159
2.25
2.40
2.8
1.9
pmol/l
86.0
89.8
0.18
19
84
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
53
427
2.84
2.35
6.0
4.6
mu/l
1.9
1.9
0.05
46
390
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
9
30
3.34
2.25
2.1
1.8
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
7
19
4.02
2.22
2.7
1.7
—
—
—
0
0
(3020891) Body temperature
7
19
4.02
2.22
10.0
2.9
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
53
429
2.79
2.18
8.7
5.1
mmol/mol
43.5
40.1
1.12
48
402
(3023368) Bacteria identified in Blood by Culture
21
116
2.24
2.13
9.8
4.1
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
13
58
2.58
2.08
13.5
3.5
mmol/l
1.1
1.0
0.29
13
53
(3000991) Gas panel - Venous blood
9
34
2.93
1.96
22.1
5.2
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
8
28
3.13
1.94
7.4
2.4
kpa
4.5
4.6
—
8
28
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
54
450
2.74
1.92
5.4
4.2
mmol/l
6.3
5.9
1.27
48
414
(3015377) Calcium [Moles/volume] in Serum or Plasma
24
147
2.04
1.85
3.5
3.3
mmol/l
2.3
2.4
0.45
19
130
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
19
3.38
1.70
6.3
2.5
%
1.3
1.1
—
6
19
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
5
15
3.53
1.55
1.4
1.2
—
—
—
0
0
(3000492) Spirometry study
9
38
2.60
1.53
1.1
1.6
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
55
479
2.50
1.52
5.8
4.5
mmol/l
2.6
2.8
0.51
49
443
(3044889) 12 lead EKG panel
41
316
1.91
1.52
5.9
3.5
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
27
183
1.85
1.50
3.8
3.9
ng/l
57.8
26.4
0.53
18
125
(40758558) Short blood count panel - Blood
19
115
1.95
1.47
7.5
7.7
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
27
185
1.82
1.43
16.0
9.4
e9/l
0.0
0.0
0.50
22
155
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
5
17
3.11
1.38
1.2
1.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
11
55
2.22
1.37
2.3
1.7
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
8
34
2.55
1.35
23.6
5.2
mmol/l
1.2
1.4
—
8
34
(3031040) Bacteria [#/volume] in Urine by Automated count
39
303
1.80
1.33
7.7
4.1
—
24.3
—
0
7
(3018418) pH of Serum or Plasma
19
119
1.87
1.32
13.1
4.0
ph
7.4
7.4
—
5
23
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
5
18
2.93
1.31
29.0
6.3
mmol/l
25.2
24.3
—
5
18
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
15
88
1.93
1.25
2.1
1.6
mg/l
0.4
1.3
—
9
80
(3026008) Bacteria identified in Urine by Culture
19
121
1.83
1.25
5.2
2.9
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
6
26
2.45
1.22
29.7
7.0
%
91.5
94.7
—
6
26
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
52
450
2.05
1.21
4.6
3.6
mmol/l
1.6
1.3
1.72
45
417
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
16
98
1.86
1.18
3.0
2.3
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
13
74
1.96
1.18
2.2
1.8
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
54
478
2.13
1.17
36.1
13.5
mg/l
26.9
23.6
0.22
48
367
(40760892) CBC W Ordered Manual Differential panel - Blood
16
99
1.84
1.14
4.3
6.1
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
10
52
2.10
1.14
8.0
1.7
g/l
2.3
2.5
—
10
46
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
53
467
2.03
1.12
5.1
4.0
mmol/l
1.3
1.5
1.39
46
433
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
53
467
2.03
1.12
5.3
4.0
mmol/l
4.5
4.7
0.52
47
435
(46235355) HIV 1 and 2 tests - Meaningful Use set
15
92
1.84
1.10
1.9
1.8
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
38
303
1.67
1.09
4.8
3.2
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
17
109
1.78
1.08
7.7
3.5
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
29
217
1.64
1.06
8.6
3.7
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
22
2.38
1.05
4.0
2.2
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
16
102
1.77
1.03
1.5
1.4
g/l
2.4
2.2
—
9
62
(3033658) Prothrombin time (PT) actual/Normal
17
111
1.74
1.02
8.3
3.4
%
96.4
93.6
0.21
17
111
(3044640) Blood type and Crossmatch panel - Blood
20
139
1.65
0.95
3.5
2.3
—
—
—
0
0
(3015736) pH of Urine
24
175
1.61
0.95
6.8
3.1
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
55
500
2.01
0.95
31.4
12.6
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
6
28
2.26
0.94
29.7
6.5
%
0.6
0.7
—
6
28
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
6
28
2.26
0.94
29.7
6.6
%
2.0
1.6
—
6
28
(40761535) Cells panel - Urine sediment
8
43
1.99
0.92
4.9
3.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
8
44
1.94
0.90
1.1
1.2
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
6
30
2.11
0.89
1.8
1.7
e9/l
71.1
77.1
—
6
25
(3009542) Hematocrit [Volume Fraction] of Blood
48
417
1.71
0.89
38.3
13.2
%
40.0
40.3
0.14
28
325
(3032080) INR in Blood by Coagulation assay
26
196
1.57
0.89
12.0
6.1
inr
1.0
1.1
—
6
58
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
50
441
1.74
0.85
22.4
12.4
ml/min/173m2
80.3
85.4
0.64
43
367
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
6
33
1.91
0.81
1.5
1.3
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
6
33
1.91
0.81
1.5
1.9
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
26
200
1.52
0.80
2.5
2.0
—
—
—
0
0
(3002256) Pathology report gross observation
9
56
1.71
0.77
1.1
1.2
—
—
—
0
0
(4010399)
7
38
1.95
0.77
1.6
1.4
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
5
25
2.09
0.74
1.2
2.4
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
5
93
0.50
0.74
1.6
1.4
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
38
320
1.50
0.74
5.9
3.8
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
21
157
1.51
0.72
5.6
3.2
u/l
37.0
28.3
0.46
21
148
(4035726)
7
43
1.71
0.69
1.1
1.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
21
160
1.48
0.66
5.2
2.9
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
8
51
1.65
0.63
2.1
1.9
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
24
191
1.42
0.59
11.5
4.1
g/l
33.8
35.8
1.14
24
185
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
23
0.00
0.59
0.0
1.7
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
9
60
1.59
0.58
8.4
8.4
—
—
—
0
0
(3003338) MCHC [Mass/volume]
45
403
1.44
0.55
46.9
17.5
g/l
333.2
332.8
0.15
45
403
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
6
39
1.60
0.55
12.5
3.4
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
54
507
1.57
0.44
34.5
15.5
umol/l
91.3
74.0
0.78
54
507
(3014051) Protein [Presence] in Urine by Test strip
0
15
0.00
0.42
0.0
1.7
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
(3019225) pH of Specimen
5
35
1.47
0.40
1.8
6.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
5
36
1.42
0.39
2.2
3.0
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
14
176
0.73
0.39
3.3
2.7
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
16
128
1.34
0.37
5.8
2.7
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
12
92
1.38
0.35
1.5
1.7
pmol/l
498.4
483.8
0.04
12
78
(3041096) Erythrocytes [Presence] in Urine by Automated
11
140
0.74
0.32
3.4
2.7
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
8
61
1.36
0.30
1.6
1.2
—
—
—
0
0
(3013512) EKG study
14
116
1.27
0.25
4.4
3.6
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
26
232
1.21
0.24
8.8
4.3
estimate
0.0
0.0
—
5
48
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
2.5
—
17.8
—
0
10
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3000570) Elastase.pancreatic [Mass/mass] in Stool
0
14
0.00
0.20
0.0
1.6
—
234.4
—
0
8
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
15
133
1.17
0.13
1.4
1.5
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
21
192
1.14
0.13
6.3
3.4
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
14
126
1.14
0.10
5.9
4.7
%
18.0
20.7
—
5
71
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
9
87
1.04
0.07
1.6
1.5
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
7.7
—
182.6
—
0
6
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022145) Colonoscopy Study observation
5
55
0.90
0.00
1.4
1.3
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
0
5
0.00
0.00
0.0
1.6
—
92.2
—
0
5
(3035637) Corticotropin [Mass/volume] in Plasma
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
5
50
1.00
0.00
3.2
2.9
u/l
56.0
27.6
—
5
42
(40768795) Lymph node Pathology biopsy report
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
10.8
—
0.6
—
0
5
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
5
52
0.96
0.00
2.2
2.0
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
1.0
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint H8_EXT_MALIGN and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
H8_EXT_MALIGN 1.384 [0.95, 2.01] 0.086
Birth year 0.989 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 238 males with H8_EXT_MALIGN died.

Mortality risk

Mortality risk for people of age

years, who have H8_EXT_MALIGN.

N-year risk Females Males
1 No data 0.279%
5 No data 1.591%
10 No data 4.158%
15 No data 8.048%
20 No data 13.472%

Relationships between endpoints

↥

Index endpoint: H8_EXT_MALIGN – Malignant otitis externa

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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