No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
60 |
4. Check minimum number of eventsNone |
60 |
5. Include endpointsNone |
60 |
6. Filter based on genotype QC (FinnGen only) |
60 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H20
- Name in latin
- Iridocyclitis phakogenes
Similar endpoints
↥List of similar endpoints to
Lens-induced iridocyclitis
based on the number of shared cases.
Similar with more cases:
- Iridocyclitis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 330 | 171 | 157 |
| Only index persons | 311 | 165 | 146 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 53.04 | 53.69 | 52.23 |
| Only index persons | 53.04 | 53.29 | 52.76 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 60 | 33 | 27 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 57.46 | 54.93 | 60.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 55
- Matched controls
- 551
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H20.2
ICD-10 Finland
Lens-induced iridocyclitis
+∞
78.8
55
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
+∞
39.4
33
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
16.5
15
*
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
61.2
12.6
14
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
10.8
11.2
23
34
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
75.1
11.1
12
*
S01ED01
ATC
timolol; ophthalmic
23.7
9.5
13
7
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
19.2
7.6
11
7
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
8.9
7.5
16
24
S01ED51
ATC
timolol, combinations; ophthalmic
8.9
7.1
15
22
S01FA04
ATC
cyclopentolate; ophthalmic
45.8
7.0
8
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
78.6
6.6
7
*
H26.2
ICD-10 Finland
Complicated cataract
78.6
6.6
7
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
+∞
6.4
6
*
S01EA03
ATC
apraclonidine; ophthalmic
+∞
6.4
6
*
WX140
NOMESCO Finland
Parabulbar anesthesy
9.2
6.0
12
16
Mortality – FinRegistry
↥Association
Association between endpoint H7_IRIDOLENS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have H7_IRIDOLENS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: H7_IRIDOLENS – Lens-induced iridocyclitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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