No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1791 |
4. Check minimum number of eventsNone |
1791 |
5. Include endpointsNone |
1791 |
6. Filter based on genotype QC (FinnGen only) |
1791 |
Control definitions (FinnGen only)
- Control exclude
- H7_CONJUNCTIVA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H10
- Name in latin
- Conjunctivitis allergica acuta
Similar endpoints
↥List of similar endpoints to
Atopic conjunctivitis
based on the number of shared cases.
Similar with more cases:
- Allergic conjunctivitis
- Conjunctivitis
- Disorders of conjunctiva
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18915 | 10051 | 8786 |
| Only index persons | 16337 | 9105 | 7232 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.29 | 0.25 |
| Only index persons | 0.31 | 0.33 | 0.28 |
| Median age at first event (years) | |||
| Whole population | 21.79 | 30.09 | 12.19 |
| Only index persons | 25.18 | 32.97 | 15.38 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1791 | 1279 | 512 |
| Unadjusted period prevalence (%) | 0.38 | 0.44 | 0.23 |
| Median age at first event (years) | 41.61 | 42.78 | 38.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1594
- Matched controls
- 15940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01GX01
ATC
cromoglicic acid; ophthalmic
12.4
323.0
852
1347
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
4503599627370496.0
323.0
1593
108
S01GX08
ATC
ketotifen; ophthalmic
16.1
125.3
210
149
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.5
114.5
787
3478
H04.10
ICD-10 Finland
Dry eye syndrome
6.2
106.4
318
620
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.5
102.0
648
2631
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
7.2
98.3
256
411
R06AE07
ATC
cetirizine; oral
3.1
97.4
929
4993
R06AX27
ATC
desloratadine; oral
3.0
82.0
646
2943
S01GX09
ATC
olopatadine; ophthalmic
16.9
80.6
131
84
S01GX02
ATC
levocabastine; ophthalmic
7.7
79.2
195
284
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.9
78.5
284
675
E0000UV
ATC
NA
2.7
73.4
797
4346
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
6.9
71.0
188
303
H02AB06
ATC
prednisolone; systemic
2.5
63.6
799
4593
L20.0
ICD-10 Finland
Besnier prurigo
4.3
62.8
257
681
R06AE09
ATC
levocetirizine; oral
3.3
62.4
366
1314
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.9
61.0
280
823
R03AC02
ATC
salbutamol; inhalant
2.4
60.4
963
6198
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
6.1
59.2
172
312
H10.4
ICD-10 Finland
Chronic conjunctivitis
109.3
58.3
63
6
S01GX05
ATC
lodoxamide; ophthalmic
47.2
55.9
68
15
R06AX22
ATC
ebastine; oral
3.0
54.1
360
1395
R06AX13
ATC
loratadine; oral
3.0
53.3
351
1351
C01CA24
ATC
epinephrine; parenteral
4.5
52.8
202
497
XQ800
NOMESCO Finland
Prick test
3.9
52.4
239
693
R03DC03
ATC
montelukast; oral
3.0
50.8
353
1401
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
50.3
348
1378
R01AD09
ATC
mometasone; nasal
2.2
50.2
831
5246
S01GX06
ATC
emedastine; ophthalmic
22.5
47.4
69
32
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
4.7
46.2
166
382
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.7
45.5
366
1582
R01AD08
ATC
fluticasone; nasal
2.3
43.7
515
2723
J30.3
ICD-10 Finland
Other allergic rhinitis
5.7
42.3
128
242
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
6.8
42.3
110
171
E000001
ATC
NA
2.4
41.4
417
2025
Z51.6
ICD-10 Finland
Desensitization to allergens
14.2
41.3
71
52
D07AA02
ATC
hydrocortisone; topical
2.7
40.3
320
1359
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
39.4
341
1519
H01.0
ICD-10 Finland
Blepharitis
4.4
38.8
148
360
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
5.9
38.5
112
202
R03BA05
ATC
fluticasone; inhalant
2.5
38.0
357
1663
D07AC13
ATC
mometasone; topical
2.2
36.8
490
2698
XQ802
NOMESCO Finland
Epicutan test
4.8
36.2
127
284
R01AD12
ATC
fluticasone furoate; nasal
2.1
35.2
563
3338
R03BA02
ATC
budesonide; inhalant
2.4
34.6
332
1555
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.2
34.4
199
685
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
9.5
33.5
70
77
R06AX26
ATC
fexofenadine; oral
3.6
32.2
153
452
E000002
ATC
NA
2.6
32.1
254
1067
S01AD03
ATC
aciclovir; ophthalmic
5.8
31.0
90
162
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
30.3
468
2698
S01GX04
ATC
nedocromil; ophthalmic
10.9
29.6
57
54
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.1
28.9
406
2248
T78.4
ICD-10 Finland
Allergy, unspecified
3.8
28.9
129
362
R03BA01
ATC
beclometasone; inhalant
2.5
27.5
243
1078
D07AC01
ATC
betamethasone; topical
1.9
27.0
513
3175
R01AD01
ATC
beclometasone; nasal
2.4
27.0
259
1198
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.6
26.8
216
910
D11AH01
ATC
tacrolimus; topical
11.4
26.7
50
45
J01AA02
ATC
doxycycline; systemic
1.8
26.4
1134
9156
R03AC03
ATC
terbutaline; inhalant
2.4
26.3
251
1158
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
26.2
822
5993
J01DB01
ATC
cefalexin; oral
1.9
25.4
1292
10966
F03
ICPC
Eye discharge
3.1
25.3
146
499
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
24.4
413
2434
J01FA10
ATC
azithromycin; systemic
1.7
24.2
1011
7959
D07AB08
ATC
desonide; topical
2.5
24.2
200
851
J45
ICD-10 Finland
Asthma
2.7
23.9
180
728
D11AX14
ATC
[U] tacrolimus; topical
17.2
23.6
37
22
D11AH02
ATC
pimecrolimus; topical
21.7
23.5
34
16
H57.1
ICD-10 Finland
Ocular pain
4.5
23.4
85
197
XCK00
NOMESCO Finland
Perimetry
3.5
23.4
115
349
R96
ICPC
Asthma
2.8
23.4
164
636
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
22.9
592
4012
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
4.0
22.7
93
242
H02AB04
ATC
methylprednisolone; systemic
2.3
22.3
229
1091
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.3
21.6
220
1040
R06.0
ICD-10 Finland
Dyspnoea
1.9
21.1
349
2023
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
6.5
21.1
55
87
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.7
20.4
93
266
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.3
20.3
207
979
114
Kela drug reimbursment
Glaucoma
3.2
19.5
108
359
R03AK07
ATC
formoterol and budesonide; inhalant
2.0
19.3
296
1664
E000003
ATC
NA
3.4
19.2
96
296
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
4.4
19.0
69
161
Z71.8
ICD-10 Finland
Other specified counselling
1.8
18.9
406
2564
H10.5
ICD-10 Finland
Blepharoconjunctivitis
7.2
18.7
45
64
N05BB01
ATC
hydroxyzine; systemic
2.7
18.6
129
495
WQ000
NOMESCO Finland
Hyposensibilisation
12.5
18.6
33
27
H16.0
ICD-10 Finland
Corneal ulcer
3.3
18.2
96
308
H16.2
ICD-10 Finland
Keratoconjunctivitis
14.5
18.1
30
21
A02BC03
ATC
lansoprazole; oral
1.8
18.0
391
2469
H10
ICD-10 Finland
Conjunctivitis
2.7
17.8
126
491
R51.80
ICD-10 Finland
Headache
1.9
17.8
277
1561
Z3231
NOMESCO Finland
Registered nurse
1.7
17.4
396
2535
J01DA01
ATC
[U] cefalexin; systemic
1.6
17.4
935
7532
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
17.2
271
1534
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
17.2
349
2154
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
17.0
426
2805
F29
ICPC
Eye symptom/complaint other
2.4
16.9
147
640
S01ED01
ATC
timolol; ophthalmic
4.7
16.9
58
128
S01AX11
ATC
[U] ofloxacin; ophthalmic
4.2
16.9
64
156
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
16.9
270
1536
R05
ICD-10 Finland
Cough
1.9
16.8
293
1717
M79.6
ICD-10 Finland
Pain in limb
1.6
16.7
517
3613
S01ED51
ATC
timolol, combinations; ophthalmic
3.1
16.5
95
324
A02BC02
ATC
pantoprazole; systemic
1.6
16.5
875
6979
Z00.0
ICD-10 Finland
General medical examination
1.8
16.5
296
1752
J01FA06
ATC
roxithromycin; oral
1.6
16.4
573
4124
A02BC05
ATC
esomeprazole; systemic
1.6
16.4
550
3916
H20.1
ICD-10 Finland
Chronic iridocyclitis
9.3
16.2
33
36
M25.5
ICD-10 Finland
Pain in joint
1.7
15.9
429
2878
E000006
ATC
NA
2.5
15.8
131
556
J01FA09
ATC
clarithromycin; systemic
1.6
15.8
490
3414
S01EC04
ATC
brinzolamide; ophthalmic
4.3
15.6
58
139
E000007
ATC
NA
2.6
15.6
116
466
R42
ICD-10 Finland
Dizziness and giddiness
1.8
15.6
288
1720
S01EE01
ATC
latanoprost; ophthalmic
3.3
15.5
78
243
M54.5
ICD-10 Finland
Low back pain
1.6
15.3
488
3419
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
15.0
375
2453
N03AX12
ATC
gabapentin; oral
2.0
15.0
216
1178
A92
ICPC
Allergy/allergic reaction NOS
3.6
15.0
68
195
F02
ICPC
Red eye
3.0
14.8
85
290
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
57.2
14.8
17
*
H15.1
ICD-10 Finland
Episcleritis
5.4
14.3
42
79
J01FF01
ATC
clindamycin; systemic
1.7
14.2
373
2467
S01EX03
ATC
NA
6.6
14.2
36
56
D07CC01
ATC
betamethasone and antibiotics; topical
2.0
14.1
195
1046
S01EC03
ATC
dorzolamide; ophthalmic
8.1
14.1
31
39
D07AD01
ATC
clobetasol; topical
1.9
14.0
211
1168
H02AB07
ATC
prednisone; oral
2.0
14.0
196
1056
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
14.0
365
2413
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.9
14.0
211
1169
ZYC01
NOMESCO Finland
Remote contact by phone
2.9
13.9
86
309
N02BE01
ATC
paracetamol; systemic, rectal
1.6
13.9
1255
11111
J45.8
ICD-10 Finland
Mixed asthma
3.7
13.9
61
171
S01EC01
ATC
acetazolamide; systemic
5.1
13.9
43
86
R01AC01
ATC
cromoglicic acid; nasal
3.3
13.8
71
225
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
13.8
258
1541
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
13.8
617
4665
L27.2
ICD-10 Finland
Dermatitis due to ingested food
5.2
13.7
42
83
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
13.7
244
1436
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
13.6
13
*
R02
ICPC
Shortness of breath/dyspnoea
2.0
13.5
173
899
R74
ICPC
Upper respiratory infection acute
1.5
13.4
523
3824
D02AE01
ATC
carbamide; topical
2.4
13.3
114
494
R01AD11
ATC
triamcinolone; nasal
2.2
13.3
134
630
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
5.5
13.2
38
70
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
6.3
13.1
34
55
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.3
13.0
127
587
J05AB01
ATC
aciclovir; systemic
1.7
12.9
318
2065
N02AX02
ATC
tramadol; systemic, rectal
1.5
12.8
515
3779
J30.19
ICD-10 Finland
Pollen allergy UNS
3.4
12.7
61
184
R03BA08
ATC
ciclesonide; inhalant
2.3
12.7
125
580
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
12.6
301
1933
H10.2
ICD-10 Finland
Other acute conjunctivitis
6.0
12.6
34
58
F01
ICPC
Eye pain
3.4
12.6
61
186
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
4.5
12.5
44
101
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
12.5
111
490
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
12.5
749
5990
R06AX12
ATC
terfenadine; oral
2.9
12.3
74
262
M03BX02
ATC
tizanidine; oral
1.5
12.3
889
7374
S01XA18
ATC
ciclosporin; ophthalmic
16.0
12.1
19
12
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
12.0
307
2004
ZXA10
NOMESCO Finland
Bilateral
1.7
12.0
246
1509
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
5.6
12.0
34
62
D02AX
ATC
Other emollients and protectives
2.8
11.9
75
274
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
2.6
11.9
89
359
S01EA03
ATC
apraclonidine; ophthalmic
10.6
11.8
22
21
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
11.7
794
6477
R01AD05
ATC
budesonide; nasal
2.3
11.7
111
508
S18
ICPC
Laceration/cut
1.5
11.7
541
4084
RD211
NOMESCO Finland
NA
2.8
11.6
73
266
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
6.9
11.6
28
41
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
4.9
11.6
37
77
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
11.5
110
506
S01BC03
ATC
diclofenac; ophthalmic
4.4
11.4
40
92
WZC30
NOMESCO Finland
Teaching
1.9
11.4
171
945
S01EE05
ATC
tafluprost; ophthalmic
4.0
11.4
44
111
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
11.4
114
535
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.0
11.3
141
726
L04AA01
ATC
[U] ciclosporin; systemic
5.6
11.3
32
58
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
11.3
1115
9760
D11AX15
ATC
[U] pimecrolimus; topical
15.1
11.3
18
12
N03AX16
ATC
pregabalin; oral
1.6
11.3
301
1986
J46
ICD-10 Finland
Status asthmaticus
3.5
11.3
51
148
J02AC01
ATC
fluconazole; systemic
1.5
11.2
612
4763
N05CF01
ATC
zopiclone; oral
1.6
11.2
382
2684
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
12.8
11.1
19
15
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
8.1
11.1
24
30
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
8.1
11.1
24
30
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
11.0
125
617
R97
ICPC
Allergic rhinitis
3.7
10.8
46
127
M79.1
ICD-10 Finland
Myalgia
1.8
10.7
193
1134
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
4.5
10.6
36
81
SPAT1260
SPAT
Consultation of another employee
1.6
10.5
266
1728
TQW80
NOMESCO Finland
Local dermatologic skincare
3.4
10.5
50
151
SPAT1310
SPAT
Counselling related to known health issue
1.5
10.5
483
3620
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
10.4
297
1993
R06AX18
ATC
acrivastine; oral
3.6
10.4
46
132
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
10.3
605
4759
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
10.3
381
2724
J05AB11
ATC
valaciclovir; oral
1.8
10.2
180
1052
C07AB07
ATC
bisoprolol; oral
1.5
10.1
484
3648
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
10.1
473
3550
R03AC13
ATC
formoterol; inhalant
2.7
10.1
67
251
WX110
NOMESCO Finland
Local anesthesy
1.4
10.1
1064
9311
A01
ICPC
Pain general/multiple sites
2.1
10.1
108
523
S01ED02
ATC
betaxolol; ophthalmic
10.1
10.0
19
19
SPAT1312
SPAT
General health counselling
1.5
10.0
522
4006
N06AX11
ATC
mirtazapine; oral
1.5
10.0
424
3119
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.8
10.0
64
238
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
9.9
385
2778
A46
ICD-10 Finland
Erysipelas
1.9
9.9
149
822
SDA02
NOMESCO Finland
Parodonthologic therapy
1.5
9.9
488
3705
M01AH01
ATC
celecoxib; oral (coxibs)
1.7
9.9
212
1316
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
9.8
265
1749
A01AB09
ATC
miconazole; local oral
2.0
9.8
123
635
L01
ICPC
Neck symptom/complaint
1.7
9.8
202
1239
R01AC02
ATC
levocabastine; nasal
3.5
9.8
45
133
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
9.8
290
1965
SPAT1263
SPAT
Sampling
1.4
9.8
633
5059
M48.0
ICD-10 Finland
Spinal stenosis
2.0
9.7
124
645
R05
ICPC
Cough
1.5
9.6
337
2374
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
9.6
254
1668
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
9.6
242
1570
G44.2
ICD-10 Finland
Tension-type headache
1.7
9.6
206
1277
S01KA02
ATC
hypromellose; ophthalmic
5.1
9.6
29
58
A02BC01
ATC
omeprazole; systemic
1.5
9.6
344
2436
R83
ICPC
Respiratory infection other
1.5
9.5
421
3119
L17
ICPC
Foot/toe symptom/complaint
1.5
9.5
339
2400
L03
ICPC
Low back symptom/complaint
1.5
9.4
342
2427
H11.0
ICD-10 Finland
Pterygium
+∞
9.4
9
*
J01DA06
ATC
[U] cefuroxime; systemic
1.7
9.4
193
1182
H40.0
ICD-10 Finland
Glaucoma suspect
2.2
9.4
91
423
R53
ICD-10 Finland
Malaise and fatigue
1.6
9.4
273
1840
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
4.8
9.3
30
64
S01BC05
ATC
ketorolac; ophthalmic
3.2
9.3
47
150
R21
ICPC
Throat symptom/complaint
1.5
9.3
372
2696
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.2
9.3
92
431
N01
ICPC
Headache
1.7
9.2
211
1333
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
9.2
130
701
L20
ICD-10 Finland
Atopic dermatitis
2.9
9.2
53
184
SPAT1360
SPAT
Extensive global examination
2.1
9.1
99
483
D07BC01
ATC
betamethasone and antiseptics; topical
1.8
9.1
148
841
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
9.1
113
581
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
9.1
182
1105
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
11.5
9.1
16
14
S29
ICPC
Skin symptom/complaint other
1.6
9.1
229
1485
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
3.3
9.1
43
131
M01AH05
ATC
etoricoxib; oral
1.4
9.0
794
6664
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.5
8.9
355
2564
E000004
ATC
NA
3.5
8.9
40
117
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.3
8.8
81
366
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
8.7
111
578
H10.8
ICD-10 Finland
Other conjunctivitis
7.2
8.7
20
28
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
7.2
8.7
20
28
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.9
8.7
51
180
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
14.1
8.7
14
10
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
8.7
505
3934
S06.0
ICD-10 Finland
Concussion
1.8
8.7
155
908
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.7
508
3961
F70
ICPC
Conjunctivitis infectious
3.0
8.6
47
159
J31.0
ICD-10 Finland
Chronic rhinitis
1.9
8.6
118
634
C07AA05
ATC
propranolol; systemic
1.5
8.5
275
1895
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.7
8.5
55
207
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
8.5
226
1487
M79.7
ICD-10 Finland
Fibromyalgia
2.7
8.4
57
218
A02BA02
ATC
ranitidine; systemic
1.6
8.4
224
1475
H16.9
ICD-10 Finland
Keratitis, unspecified
3.8
8.3
34
92
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.2
363
2677
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
8.2
116
627
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
8.1
114
615
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
8.1
439
3367
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
8.1
426
3254
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
8.0
179
1121
SPAT1216
SPAT
Assessment of functional ability
1.7
8.0
166
1017
R03AC12
ATC
salmeterol; inhalant
2.8
8.0
51
189
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.0
8.0
44
150
CHD00
NOMESCO Finland
Laser trabeculoplasty
5.9
8.0
21
36
J01CA04
ATC
amoxicillin; systemic
1.4
8.0
1272
11686
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
7.9
118
654
S10
ICPC
Boil/carbuncle
2.2
7.8
78
369
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
3.7
7.8
32
88
J01FA01
ATC
erythromycin; systemic
1.6
7.8
226
1520
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
7.7
138
807
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.2
7.7
79
376
XG410
NOMESCO Finland
Flow-volume spirometry
2.5
7.7
60
250
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
6.4
7.7
19
30
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
7.7
124
704
SPAT1059
SPAT
Spirometry at the office
2.3
7.7
71
323
XCH00
NOMESCO Finland
Eye pressure measurement
2.7
7.7
50
190
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.5
7.6
57
234
M01AB05
ATC
diclofenac; systemic, rectal
1.3
7.6
876
7591
H53.1
ICD-10 Finland
Subjective visual disturbances
2.1
7.6
81
394
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.7
7.6
142
844
M01AC06
ATC
meloxicam; systemic, rectal
1.4
7.6
440
3411
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
7.6
117
654
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
5.2
7.6
22
43
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.6
877
7605
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
7.5
564
4569
L50.0
ICD-10 Finland
Allergic urticaria
2.9
7.5
44
157
M01AE02
ATC
naproxen; oral, rectal
1.3
7.5
831
7153
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
7.4
90
459
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.4
242
1669
C10AA05
ATC
atorvastatin; oral
1.4
7.4
354
2646
D06BX01
ATC
metronidazole; topical
1.7
7.3
138
822
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
7.3
217
1465
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.3
453
3548
M54.2
ICD-10 Finland
Cervicalgia
1.9
7.3
96
509
EMB10
NOMESCO Finland
Tonsillectomy
1.9
7.2
109
605
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
7.2
125
725
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
15.8
7.2
11
7
H11.3
ICD-10 Finland
Conjunctival haemorrhage
3.2
7.2
35
110
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
5.8
7.2
19
33
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
7.2
340
2537
K08.80
ICD-10 Finland
Toothache NOS
1.8
7.2
116
661
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
7.2
133
788
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.2
7.2
71
336
SPAT1301
SPAT
No procedures
1.4
7.1
434
3383
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.4
7.1
59
253
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.1
538
4352
R03CC02
ATC
salbutamol; systemic
1.7
7.1
141
855
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
7.1
144
878
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
7.1
134
800
D07AC14
ATC
methylprednisolone aceponate; topical
2.3
7.0
64
288
H15.0
ICD-10 Finland
Scleritis
10.1
7.0
13
13
F73
ICPC
Eye infection/inflammation other
3.2
7.0
34
107
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.6
7.0
49
193
V01AA05
ATC
tree pollen; parenteral
7.0
7.0
16
23
UJF32
NOMESCO Finland
Coloscopy
1.5
7.0
287
2078
G43.9
ICD-10 Finland
Migraine, unspecified
1.9
7.0
99
539
SPAT1153
SPAT
Removal of sutures
1.4
7.0
378
2889
49300
ICD-8 Finland
Asthma, bronchiale
3.2
6.9
34
109
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
6.9
187
1235
S01FA04
ATC
cyclopentolate; ophthalmic
4.8
6.8
21
44
SPAT1131
SPAT
Colonoscopy
2.6
6.8
45
173
S01EB01
ATC
pilocarpine; ophthalmic
9.4
6.8
13
14
P06
ICPC
Sleep disturbance
1.7
6.8
143
883
J30.1
ICD-10 Finland
Allergic rhinitis due to pollen
40.2
6.8
8
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
6.7
110
627
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
3.5
6.7
29
84
SPAT1359
SPAT
Use of symptom diary
3.0
6.7
35
117
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
6.7
72
353
J20
ICD-10 Finland
Acute bronchitis
1.7
6.7
124
739
J35.0
ICD-10 Finland
Chronic tonsillitis
1.9
6.7
93
504
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
6.7
851
7423
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.7
6.6
148
928
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.9
6.6
98
540
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
5.5
6.6
18
33
R03AK08
ATC
formoterol and beclometasone; inhalant
2.4
6.6
53
226
L20.8
ICD-10 Finland
Other atopic dermatitis
4.6
6.6
21
46
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
2.7
6.6
43
164
R13
ICD-10 Finland
Dysphagia
2.1
6.6
71
348
K30
ICD-10 Finland
Functional dyspepsia
1.7
6.6
138
853
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.8
6.6
112
647
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
10.1
6.5
12
12
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
6.9
6.5
15
22
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.5
558
4587
A07AA02
ATC
nystatin; oral
2.0
6.5
73
365
K07.60
ICD-10 Finland
Snapping jaw
1.9
6.5
85
448
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
6.5
104
590
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
6.5
519
4224
R52.2
ICD-10 Finland
Other chronic pain
2.5
6.4
46
185
SPAT1009
SPAT
Measurement of intraocular pressure
4.1
6.4
23
57
J01MA14
ATC
moxifloxacin; systemic
1.8
6.4
98
549
N17
ICPC
Vertigo/dizziness
1.7
6.4
134
826
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
3.2
6.4
31
99
J01MA12
ATC
levofloxacin; systemic
1.5
6.3
196
1333
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.5
6.3
48
198
ZXA00
NOMESCO Finland
Right side
1.4
6.3
293
2169
H20
ICD-10 Finland
Iridocyclitis
8.2
6.3
13
16
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.3
792
6868
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
6.3
117
695
A03
ICPC
Fever
1.5
6.3
264
1918
M02AA07
ATC
piroxicam; topical
1.4
6.3
401
3143
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
18.1
6.3
9
5
H02.3
ICD-10 Finland
Blepharochalasis
2.1
6.2
68
334
HMAK
NOMESCO Finland
NA
1.6
6.2
170
1127
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
6.2
87
472
B00.10
ICD-10 Finland
Herpes simplex facialis
5.0
6.2
18
36
V01AA02
ATC
grass pollen; systemic
7.7
6.1
13
17
N03AX09
ATC
lamotrigine; oral
2.0
6.1
76
393
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
6.1
65
316
D11
ICPC
Diarrhoea
1.6
6.1
176
1180
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
6.1
92
515
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
6.0
177
1192
S21
ICPC
Skin texture symptom/complaint
1.6
6.0
150
970
H53.2
ICD-10 Finland
Diplopia
2.7
6.0
37
138
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONJUNCTIVITISATOPIC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNCTIVITISATOPIC | 0.871 [0.76, 0.99] | 0.039 |
| Birth year | 0.999 [0.99, 1.01] | 0.737 |
During the follow-up period (1.1.1998 — 31.12.2019), 495 out of 8736 females with H7_CONJUNCTIVITISATOPIC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNCTIVITISATOPIC | 1.134 [0.97, 1.32] | 0.106 |
| Birth year | 0.994 [0.98, 1.0] | 0.205 |
During the follow-up period (1.1.1998 — 31.12.2019), 326 out of 7543 males with H7_CONJUNCTIVITISATOPIC died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONJUNCTIVITISATOPIC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | 0.293% |
| 5 | 0.654% | 1.533% |
| 10 | 1.512% | 3.981% |
| 15 | 2.959% | 7.591% |
| 20 | 5.068% | 12.889% |
Relationships between endpoints
↥Index endpoint: H7_CONJUNCTIVITISATOPIC – Atopic conjunctivitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data