This is a non-core endpoint: only basic statistics are computed.
Abuse of non-dependence-producing substances
F5_ABUNONDEP
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
48 |
4. Check minimum number of eventsNone |
48 |
5. Include endpointsNone |
48 |
6. Filter based on genotype QC (FinnGen only) |
48 |
Control definitions (FinnGen only)
- Control exclude
- F5_BEHAVE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F50-F59
- Name in latin
- Abusus substantiarum dependentiam non producentium
Similar endpoints
↥List of similar endpoints to
Abuse of non-dependence-producing substances
based on the number of shared cases.
Similar with more cases:
- Behavioural syndromes associated with physiological disturbances and physical factors
- Any mental disorder
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 749 | 254 | 484 |
| Only index persons | 503 | 166 | 337 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 45.87 | 47.41 | 44.73 |
| Only index persons | 38.96 | 36.57 | 40.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 48 | 22 | 26 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 45.99 | 42.98 | 48.54 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3011288) Drugs identified in Urine by Screen method
12
11
14.21
11.52
22.8
1.3
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
11
11
12.68
9.92
20.4
1.9
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
13
18
9.53
9.34
23.2
1.8
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
14
22
8.57
9.09
21.9
1.6
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
13
20
8.54
8.55
23.2
1.7
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
13
21
8.12
8.19
23.5
1.7
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
13
21
8.12
8.19
24.0
1.6
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
13
22
7.73
7.85
7.2
1.6
—
—
—
0
0
(3042517) Benzodiazepines panel - Urine
5
0
+∞
5.29
4.6
0.0
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
22
93
3.52
4.29
4.6
2.3
u/l
205.6
181.6
0.15
22
87
(3023183) Ammonium ion [Moles/volume] in Plasma
6
5
13.42
3.87
3.3
3.0
umol/l
34.8
40.8
—
6
5
(3026008) Bacteria identified in Urine by Culture
19
92
2.76
2.75
4.5
2.8
—
—
—
0
0
(3019060) Gas panel - Arterial blood
9
25
4.18
2.74
9.1
3.3
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
7
16
4.93
2.58
1.9
4.9
mmol/l
25.0
25.5
—
7
16
(3018405) Lactate [Moles/volume] in Arterial blood
7
16
4.93
2.58
3.0
6.6
mmol/l
1.4
1.1
—
7
16
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
7
16
4.93
2.58
4.4
3.3
%
2.3
1.1
—
7
16
(3000991) Gas panel - Venous blood
9
27
3.86
2.55
5.7
6.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
7
17
4.63
2.46
3.6
3.1
—
—
—
0
0
(3012544) pH of Venous blood
9
29
3.58
2.37
4.0
2.7
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
7
18
4.36
2.35
5.9
3.2
g/l
132.4
122.5
—
7
18
(3023511) Choriogonadotropin [Units/volume] in Urine
5
10
5.43
2.12
1.8
1.4
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
31
209
2.36
2.08
9.7
4.4
mmol/l
6.4
6.7
0.29
31
194
(3044640) Blood type and Crossmatch panel - Blood
21
120
2.33
2.07
2.2
2.0
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
11
4.93
1.99
2.0
2.2
—
—
—
0
0
(3019225) pH of Specimen
8
28
3.22
1.96
4.7
5.7
—
—
—
0
0
(3026782) Osmolality of Urine
14
68
2.49
1.94
3.9
2.4
mosm/kgh2o
432.1
561.1
—
9
56
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
16
83
2.39
1.93
1.7
1.9
—
—
—
0
0
(3020891) Body temperature
6
17
3.88
1.90
6.5
3.6
—
—
—
0
0
(3035941) MCH [Entitic mass]
40
450
0.33
1.82
38.0
17.8
pg
29.8
30.3
0.49
40
440
(3026361) Erythrocytes [#/volume] in Blood
40
450
0.33
1.82
38.3
17.9
e12/l
4.5
4.6
0.35
40
437
(3024731) MCV [Entitic volume]
40
450
0.33
1.82
38.0
17.8
fl
89.8
90.7
0.34
40
440
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
13
63
2.46
1.80
1.8
2.0
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
5
13
4.16
1.76
2.4
1.2
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
6
20
3.27
1.64
1.7
1.4
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
5
15
3.59
1.56
4.2
3.3
%
0.8
0.7
—
5
15
(3000850) Epithelial cells [#/volume] in Urine
15
83
2.17
1.53
2.4
2.4
e6/l
2.5
5.9
—
10
76
(3013512) EKG study
15
83
2.17
1.53
6.9
3.8
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
6
23
2.83
1.41
3.0
6.4
%
91.7
93.3
—
6
23
(3027273) Bicarbonate [Moles/volume] in Venous blood
5
17
3.16
1.39
7.4
3.4
mmol/l
27.5
24.9
—
5
17
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
17
3.16
1.39
14.2
7.4
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
7
140
0.42
1.38
3.0
2.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
21
288
0.52
1.37
4.4
3.3
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
6
24
2.71
1.35
3.5
6.1
%
1.0
0.7
—
6
24
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
6
24
2.71
1.35
3.5
6.2
%
3.3
1.5
—
6
24
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
5
18
2.98
1.32
2.6
1.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
18
2.98
1.32
2.6
2.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
15
88
2.02
1.30
3.9
3.4
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
20
131
1.90
1.27
12.0
6.5
inr
1.6
1.2
—
8
41
(3015736) pH of Urine
21
140
1.89
1.27
7.6
3.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
37
421
0.47
1.19
25.4
11.1
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
33
389
0.51
1.18
4.9
4.1
mmol/l
2.7
2.8
0.18
27
356
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
20
2.67
1.18
1.2
1.5
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
8
41
2.14
1.15
1.5
1.8
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
7
32
2.39
1.13
1.4
1.7
—
—
—
0
0
(3022145) Colonoscopy Study observation
7
34
2.24
1.08
1.3
1.3
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
25
185
1.73
1.03
8.4
6.7
e9/l
0.1
0.2
0.76
20
164
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
20
139
1.75
1.02
5.2
3.0
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
20
139
1.75
1.02
7.5
3.8
ng/l
18.2
35.8
1.58
12
81
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
34
276
1.80
0.99
7.6
2.7
u/l
60.1
44.8
0.54
29
259
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
32
0.00
0.99
0.0
1.4
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
18
123
1.74
0.96
3.1
1.8
pmol/l
87.0
91.9
—
9
67
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
8
43
2.03
0.93
1.5
1.6
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
6
29
2.22
0.93
2.2
1.6
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
33
382
0.56
0.93
4.4
3.7
mmol/l
4.5
4.6
0.24
28
349
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
6
31
2.07
0.88
3.2
3.9
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
9
53
1.86
0.81
1.4
1.3
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
19
138
1.62
0.79
7.0
3.4
e6/l
50.7
66.1
0.12
14
98
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
18
129
1.63
0.79
8.8
4.1
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
7
41
1.83
0.74
1.1
1.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
10
62
1.77
0.72
1.9
1.6
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
5
27
1.95
0.70
1.4
1.1
—
131.0
—
0
10
(3037467) Urinalysis macro (dipstick) panel - Urine
29
240
1.53
0.66
6.1
3.9
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
8
53
1.61
0.62
2.0
2.3
g/l
2.7
2.3
—
8
46
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
19
0.00
0.62
0.0
1.6
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
21
0.00
0.61
0.0
1.6
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
34
1.87
0.61
1.2
1.1
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
0
22
0.00
0.61
0.0
1.1
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
14
100
1.56
0.60
5.5
4.6
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
23
0.00
0.60
0.0
1.6
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
34
379
0.65
0.58
21.9
12.0
%
40.7
41.0
0.15
21
302
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
22
176
1.46
0.56
3.4
3.8
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
6
39
1.61
0.55
2.2
2.3
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
5
82
0.56
0.51
3.6
1.5
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
12
87
1.51
0.48
3.2
6.3
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
15
0.00
0.42
0.0
1.7
—
5.4
—
0
10
(3045414) Leukocytes [Presence] in Urine
0
17
0.00
0.41
0.0
1.7
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
20
167
1.34
0.37
13.1
6.4
%
7.5
8.4
0.61
15
159
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
6
43
1.45
0.37
5.3
7.1
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
6
43
1.45
0.37
1.2
1.3
—
—
—
0
0
(40758558) Short blood count panel - Blood
12
92
1.41
0.36
6.3
6.4
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
7
55
1.32
0.31
1.0
2.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
10
126
0.74
0.28
1.2
1.4
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
5
71
0.67
0.28
2.0
3.4
mmol/l
2.4
2.5
—
5
61
(3002385) Erythrocyte distribution width [Ratio]
31
336
0.78
0.27
29.3
15.2
%
14.4
13.4
1.76
31
330
(3007853) Bacteria identified in Skin by Aerobe culture
5
38
1.35
0.24
1.0
2.1
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum
0
10
0.00
0.21
0.0
4.0
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
13
109
1.26
0.21
3.5
3.0
e6/l
0.1
0.4
—
8
84
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
10
83
1.26
0.17
1.5
1.6
mmol/l
1.3
1.5
—
10
68
(3023103) Potassium [Moles/volume] in Serum or Plasma
40
386
1.22
0.15
31.3
14.5
mmol/l
3.9
4.0
0.04
40
374
(46235355) HIV 1 and 2 tests - Meaningful Use set
12
107
1.16
0.09
3.1
1.9
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
7
63
1.13
0.08
3.0
2.0
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
12
108
1.15
0.08
3.5
2.8
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
35
362
0.88
0.08
23.3
11.8
ml/min/173m2
88.8
88.6
0.02
26
292
(3011397) Hemoglobin [Presence] in Urine by Test strip
9
99
0.89
0.07
12.2
3.5
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
12
112
1.10
0.03
10.4
5.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
14
145
0.95
0.00
1.4
1.8
—
—
—
0
0
(3044889) 12 lead EKG panel
24
237
1.03
0.00
5.7
3.4
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3034274) Bile acid [Moles/volume] in Serum --fasting
0
6
0.00
0.00
0.0
3.2
—
3.8
—
0
6
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
0
5
0.00
0.00
0.0
6.2
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
2.4
—
5.1
—
0
7
(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
6
0.00
0.00
0.0
7.7
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(4146454)
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007566) Smooth muscle Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood
0
5
0.00
0.00
0.0
1.4
—
727.8
—
0
5
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
4.0
—
7.7
—
0
5
(3034770) Mitochondria Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(4094501)
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
0
6
0.00
0.00
0.0
6.0
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3025271) CD3-CD16+CD56+ (Natural killer) cells [#/volume] in Blood
0
5
0.00
0.00
0.0
1.4
—
0.2
—
0
5
(3025130) Human papilloma virus identified in Specimen
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
7
70
1.00
0.00
3.3
2.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3023420) DNA double strand Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3024980) IgG subclass 4 [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
1.2
—
0
5
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
8
86
0.92
0.00
1.5
1.6
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
17.5
—
0
6
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
9
0.00
0.00
0.0
2.6
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint F5_ABUNONDEP and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_ABUNONDEP | 4.878 [3.14, 7.57] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 97 out of 279 males with F5_ABUNONDEP died.
Mortality risk
Mortality risk for people of age
years, who have F5_ABUNONDEP.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.902% |
| 5 | No data | 5.273% |
| 10 | No data | 12.758% |
| 15 | No data | 24.307% |
| 20 | No data | 38.78% |
Relationships between endpoints
↥Index endpoint: F5_ABUNONDEP – Abuse of non-dependence-producing substances
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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