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Enteropathogenic Escherichia coli infection

DOID EFO Endpoint Browser PheWeb

ENTEROPATH_E_COLI

dysentery: Acute inflammation of the intestine associated with infectious diarrhea of various etiologies, generally acquired by eating contaminated food containing toxins, biological derived from bacteria or other microorganisms. Dysentery is characterized initially by watery feces then by bloody mucoid stools. It is often associated with abdominal pain; fever; and dehydration.

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Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A04.0
  • Cause of death: ICD-10 — A04.0

2 out of 7 registries used, show all original rules.

103

4. Check minimum number of events

None

103

5. Include endpoints

None

103

6. Filter based on genotype QC (FinnGen only)

103

Control definitions (FinnGen only)

Control exclude
IBD_BACT_INTEST_INFECTIONS

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
A04
Name in latin
Infectio ab Escherichia coli enteropathogenica

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 847 440 403
Only index persons 730 388 342
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 59.41 61.54 56.93
Only index persons 58.07 59.97 55.91

-FinnGen-

Key figures

All Female Male
Number of individuals 103 50 53
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 62.11 61.95 62.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
90
Matched controls
900
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A04.0
ICD-10 Finland
Enteropathogenic Escherichia coli infection
+∞
129.6
90
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
7.8
14.6
38
77
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.2
10.3
26
48
R50.9
ICD-10 Finland
Fever, unspecified
6.1
9.6
28
62
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
+∞
9.5
9
*
Z2221
NOMESCO Finland
Medical doctor
4.0
8.0
40
151
TPH04
NOMESCO Finland
Cathetrisation of vein
4.5
8.0
32
99
R53
ICD-10 Finland
Malaise and fatigue
4.4
7.5
29
87
XF400
NOMESCO Finland
ECG with 12 standard connections
4.6
7.4
27
76
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.5
6.7
14
19
R4110
NOMESCO Finland
Physiotherapy
3.5
6.6
35
137
A04.5
ICD-10 Finland
Campylobacter enteritis
74.9
6.5
7
*
J01MA02
ATC
ciprofloxacin; systemic
3.1
6.3
47
232
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.4
6.1
22
61
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.4
6.0
15
27

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
38
55
10.36
27.11
2.0
1.6
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
22
23
11.89
19.50
1.3
1.3
—
—
—
0
0
(3000991) Gas panel - Venous blood
27
70
4.87
10.18
10.4
10.3
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
29
80
4.65
10.14
4.9
8.0
mmol/l
2.6
1.7
0.66
22
63
(3012544) pH of Venous blood
29
82
4.53
9.81
4.9
7.9
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
51
227
3.47
8.86
7.6
4.2
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
18
43
4.86
7.36
1.3
1.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
57
297
3.06
7.23
5.2
3.5
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
72
435
3.18
6.89
11.1
8.0
e9/l
0.2
0.2
0.60
63
385
(3018095) Leukocytes [#/volume] in Urine
57
303
2.97
6.88
5.5
4.0
e6/l
19.3
54.0
1.18
47
209
(3026782) Osmolality of Urine
39
170
3.08
6.69
2.6
2.8
mosm/kgh2o
539.0
565.5
0.28
33
143
(3006315) Basophils [#/volume] in Blood
70
423
3.04
6.57
10.6
7.6
e9/l
0.0
0.0
0.04
62
366
(40758558) Short blood count panel - Blood
46
224
2.90
6.43
18.8
9.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
51
264
2.85
6.34
4.7
3.4
e6/l
11.3
307.1
0.62
45
196
(3014765) Yersinia sp identified in Stool by Organism specific culture
14
31
5.07
6.19
1.6
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
14
31
5.07
6.19
1.6
1.1
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
14
31
5.07
6.19
1.6
1.1
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
69
422
2.92
6.19
10.7
7.5
e9/l
0.6
0.6
0.72
61
365
(3013650) Neutrophils [#/volume] in Blood by Automated count
75
486
3.00
5.92
21.4
11.7
e9/l
3.9
4.1
0.35
65
428
(3019198) Lymphocytes [#/volume] in Blood
69
434
2.79
5.66
10.9
7.5
e9/l
2.2
1.8
0.60
61
389
(3022096) Basophils/100 leukocytes in Blood
63
380
2.69
5.60
9.6
8.0
%
0.6
0.7
0.39
58
349
(3048689) Calprotectin [Mass/mass] in Stool
29
117
3.06
5.58
3.2
2.4
ug/g
329.0
102.3
1.44
23
87
(3003327) Ova and parasites identified in Stool by Light microscopy
14
34
4.61
5.56
2.2
1.3
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
47
247
2.66
5.50
4.5
3.3
e6/l
0.3
0.3
0.05
41
181
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
26
100
3.14
5.41
2.8
1.7
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
46
241
2.64
5.40
4.6
3.2
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
12
27
4.90
5.19
1.2
1.1
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
16
46
3.93
5.13
1.8
1.3
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
63
397
2.51
4.87
11.3
11.7
e9/l
0.0
0.0
0.50
46
323
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
25
101
2.95
4.74
2.8
1.8
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
38
193
2.54
4.64
6.2
3.7
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
50
289
2.42
4.60
9.0
8.4
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
62
396
2.42
4.54
12.8
8.0
mmol/l
1.2
1.2
0.40
56
339
(3007164) IgA [Mass/volume] in Serum or Plasma
34
167
2.55
4.42
1.4
1.5
g/l
2.3
2.2
0.10
18
98
(3021879) Hepatitis B virus core Ab [Presence] in Serum
19
69
3.15
4.30
1.5
1.6
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
14
42
3.70
4.22
2.4
1.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
31
149
2.55
4.19
4.6
3.1
e6/l
0.8
1.0
0.20
19
85
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
29
136
2.58
4.12
4.8
3.3
e6/l
1.6
2.9
0.45
17
72
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
9
14
6.93
4.08
1.2
1.8
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
9
14
6.93
4.08
1.2
1.8
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
30
145
2.51
3.99
2.9
1.9
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
15
6.46
3.91
1.1
1.2
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
20
80
2.86
3.83
3.3
2.8
g/l
0.2
0.2
0.66
20
75
(3004119) Hemoglobin [Mass/volume] in Venous blood
14
46
3.36
3.69
4.6
6.5
g/l
124.1
128.0
0.25
14
46
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
13
41
3.48
3.64
4.5
5.7
%
1.2
1.5
0.39
13
41
(3044640) Blood type and Crossmatch panel - Blood
43
254
2.19
3.57
3.1
2.3
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
13
42
3.40
3.51
1.1
1.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
36
199
2.24
3.50
2.6
2.2
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
44
268
2.12
3.34
6.5
3.2
u/l
29.3
34.6
0.81
44
253
(3023520) Reticulocytes [#/volume] in Blood
17
67
2.84
3.33
3.8
5.5
e9/l
65.8
66.6
—
10
52
(3044941) Cell count panel - Synovial fluid
6
7
9.00
3.30
1.2
1.0
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
7
11
6.73
3.24
1.4
1.3
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
11
34
3.50
3.16
5.6
3.8
mmol/l
23.6
24.3
0.26
11
34
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
56
380
2.04
3.12
4.6
3.9
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
5
5
10.41
3.01
1.2
1.0
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
5
5
10.41
3.01
1.2
1.0
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
30
3.58
2.99
5.3
2.8
—
—
—
0
0
(3015736) pH of Urine
48
314
1.99
2.91
6.4
3.7
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
6
9
6.99
2.91
1.7
1.2
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
21
99
2.41
2.89
1.9
1.8
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
11
37
3.21
2.78
6.2
2.9
%
53.3
49.9
0.15
11
37
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
49
328
1.94
2.74
2.0
2.0
pmol/l
103.9
91.8
1.12
28
161
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
15
62
2.66
2.68
7.6
5.5
ng/l
122.4
80.7
0.45
15
56
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
32
189
2.01
2.53
1.5
1.3
u/ml
1.4
0.9
—
9
50
(3026008) Bacteria identified in Urine by Culture
40
256
1.92
2.51
4.3
2.8
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
29
166
2.04
2.50
1.8
1.9
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
22
113
2.20
2.49
1.5
1.7
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
13
52
2.72
2.47
1.9
1.6
—
—
—
0
0
(40761535) Cells panel - Urine sediment
15
65
2.53
2.45
6.1
3.5
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
6
13
4.83
2.30
1.0
1.2
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
11
42
2.81
2.27
1.1
1.6
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
5
9
5.77
2.24
1.0
1.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
13
55
2.56
2.22
4.2
2.0
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
71
562
1.85
2.15
6.3
4.5
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
8
25
3.38
2.14
1.0
1.8
—
—
—
0
0
(3020891) Body temperature
9
31
3.08
2.13
9.7
3.1
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
6
15
4.18
2.07
1.0
1.0
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
6
15
4.18
2.07
1.5
1.4
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
17
87
2.14
1.93
13.7
7.4
mmol/l
2.6
1.3
1.08
12
70
(3024891) Influenza virus A+B Ag [Presence] in Specimen
7
23
3.19
1.83
1.3
1.3
—
—
—
0
0
(3003338) MCHC [Mass/volume]
79
661
1.84
1.83
47.8
20.4
g/l
329.6
333.1
2.96
79
656
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
11
48
2.45
1.77
17.8
8.2
%
0.7
0.7
0.10
11
48
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
6
18
3.47
1.77
1.5
1.8
—
—
—
0
0
(3019060) Gas panel - Arterial blood
12
55
2.34
1.75
4.7
3.7
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
11
49
2.39
1.70
17.8
8.1
%
1.2
1.5
0.35
11
49
(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
6
19
3.29
1.68
1.8
7.5
—
4920.0
—
0
5
(3037756) Immunofixation for Serum or Plasma
6
20
3.12
1.60
1.3
1.5
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
6
20
3.12
1.60
1.8
1.9
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
23
142
1.80
1.55
1.7
1.7
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
21
2.97
1.53
1.7
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
63
510
1.61
1.50
3.7
3.0
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
7
28
2.61
1.48
5.0
5.6
mmol/l
1.1
1.4
—
7
28
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
5
16
3.23
1.45
1.0
1.4
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
5
16
3.23
1.45
1.8
1.4
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
15
82
1.97
1.45
2.7
1.8
nmol/l
395.3
371.0
0.16
15
76
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
25
162
1.72
1.43
4.8
3.5
ng/l
302.3
118.0
0.27
20
132
(3000492) Spirometry study
12
61
2.09
1.39
1.8
1.6
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
10
48
2.20
1.32
19.5
8.4
%
89.4
93.5
—
10
48
(3024928) Oxygen saturation in Venous blood
5
18
2.86
1.30
3.0
10.5
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
17
102
1.80
1.26
1.2
1.2
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
19
2.71
1.23
1.0
1.3
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
83
735
1.67
1.22
25.8
13.6
ml/min/173m2
81.6
81.5
0.01
67
579
(3044889) 12 lead EKG panel
64
535
1.52
1.21
4.1
4.0
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
26
181
1.58
1.13
1.4
2.0
mg/l
1.5
1.0
0.88
19
140
(3020961) Endomysium IgA Ab [Titer] in Serum
8
41
2.03
1.11
1.0
1.1
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
21
2.45
1.10
1.0
1.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
39
300
1.48
1.08
7.2
3.7
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
39
300
1.48
1.08
2.3
2.1
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
10
53
1.98
1.05
18.4
11.7
mmol/l
26.8
24.6
—
10
53
(3045414) Leukocytes [Presence] in Urine
7
34
2.13
1.05
1.9
1.6
—
—
—
0
0
(3034860) Kappa light chains.free [Mass/volume] in Serum
5
22
2.34
1.04
9.6
3.3
mg/l
76.4
348.8
—
5
17
(3034770) Mitochondria Ab [Titer] in Serum
5
22
2.34
1.04
1.0
1.2
—
—
—
0
0
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
5
22
2.34
1.04
9.6
3.3
mg/l
58.0
27.4
—
5
17
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
14
218
0.59
1.04
2.3
1.6
mmol/l
1.1
1.4
1.76
14
185
(3042936) Bacteria identified in Isolate by Culture
20
135
1.60
0.98
2.4
1.8
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
6
27
2.30
0.95
1.0
1.7
—
—
—
0
0
(3022145) Colonoscopy Study observation
13
80
1.72
0.89
1.9
1.3
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
22
157
1.51
0.86
1.7
1.6
nmol/l
1140.9
1193.0
0.11
16
124
(3000330) Specific gravity of Urine by Test strip
8
46
1.80
0.85
3.4
3.6
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
78
705
1.44
0.80
36.2
17.5
%
38.4
39.9
1.44
62
497
(3036489) Thrombin time
6
33
1.87
0.80
2.5
3.6
s
33.7
21.7
—
6
33
(3022621) pH of Urine by Test strip
9
54
1.73
0.77
2.2
2.1
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
7
40
1.80
0.73
4.0
3.1
e6/l
0.0
0.1
—
7
40
(3032080) INR in Blood by Coagulation assay
41
339
1.35
0.72
12.1
7.6
inr
1.2
1.2
—
7
104
(3009343) pH of Capillary blood
10
61
1.71
0.71
2.4
4.7
—
7.4
—
0
5
(1761868) Lipid panel - Serum or Plasma
20
264
0.70
0.69
4.8
2.8
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
7
43
1.67
0.68
25.6
7.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
10
62
1.68
0.68
1.1
1.2
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
5
28
1.82
0.67
1.0
1.5
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
14
96
1.53
0.65
1.4
1.4
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
5
29
1.76
0.64
2.8
3.4
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
5
29
1.76
0.64
1.0
1.6
—
—
—
0
0
(3022313) Gas panel - Capillary blood
8
49
1.68
0.64
2.6
4.8
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
6
38
1.61
0.55
1.7
1.8
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
6
40
1.53
0.52
1.7
2.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
86
812
1.36
0.49
38.3
15.1
mg/l
34.1
23.2
1.75
78
648
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
7
50
1.43
0.46
1.3
1.6
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
8
55
1.49
0.44
1.3
1.5
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
12
88
1.41
0.42
1.3
1.6
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
3.1
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
78
734
1.26
0.40
5.4
4.8
mu/l
1.8
1.9
0.82
73
664
(3019832) Treponema pallidum Ab [Presence] in Serum
13
98
1.37
0.40
1.3
1.7
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
20
163
1.28
0.38
1.7
1.5
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
73
772
0.81
0.37
4.6
4.4
mmol/l
1.4
1.5
0.52
68
713
(4010399)
10
74
1.39
0.34
1.4
1.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
12
92
1.34
0.33
1.6
2.2
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
13
102
1.31
0.32
2.0
2.5
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
7
56
1.27
0.30
1.6
2.2
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
12
94
1.31
0.29
1.8
2.1
%
1.3
1.6
0.86
12
80
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
34
307
1.16
0.24
5.2
3.6
ng/l
38.9
38.5
0.01
27
224
(3013512) EKG study
21
240
0.84
0.23
3.4
4.0
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
24
212
1.17
0.22
4.8
3.3
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
5
42
1.20
0.22
1.2
2.1
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
0
11
0.00
0.21
0.0
1.5
—
5.7
—
0
11
(4146454)
0
10
0.00
0.21
0.0
3.9
—
—
—
0
0
(4268621)
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(4306422)
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
0
12
0.00
0.21
0.0
3.1
—
62.8
—
0
12
(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
1.2
—
1.4
—
0
5
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
3.2
—
137.5
—
0
13
(40760892) CBC W Ordered Manual Differential panel - Blood
20
175
1.18
0.20
7.8
5.2
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
12
100
1.23
0.19
32.5
28.2
—
1.6
—
0
13
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
72
747
0.88
0.19
4.3
4.0
mmol/l
1.3
1.3
0.03
67
689
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
77
792
0.89
0.15
5.3
5.0
mmol/l
2.6
2.6
0.13
70
729
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
44
1.14
0.10
3.8
2.2
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
5
45
1.12
0.10
1.2
1.0
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
5
60
0.82
0.08
3.8
2.2
e9/l
3.8
3.9
—
5
48
(40761511) CBC panel - Blood by Automated count
85
836
1.10
0.08
25.8
13.8
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
7
82
0.84
0.07
2.3
1.8
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
7
82
0.84
0.07
7.0
3.3
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
15
161
0.92
0.05
1.9
3.0
ug/l
0.6
0.7
—
8
111
(3009508) Creatinine [Moles/volume] in Urine
27
258
1.06
0.05
5.4
3.5
mmol/l
8.0
7.8
0.09
27
212
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
23
222
1.05
0.02
3.2
4.3
%
20.0
21.3
—
9
112
(3002256) Pathology report gross observation
10
93
1.08
0.02
1.2
1.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
24
235
1.03
0.00
1.3
1.5
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
76
764
0.98
0.00
4.7
4.4
mmol/l
6.1
5.9
0.75
71
696
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
10
99
1.01
0.00
29.4
7.7
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
5
53
0.94
0.00
2.2
2.2
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(4027681)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
0
8
0.00
0.00
0.0
1.4
—
91.8
—
0
8
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
11.8
—
0
5
(3038026) Centromere Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
0.00
0.0
3.2
—
110.8
—
0
5
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
6
0.00
0.00
0.0
1.7
—
38.0
—
0
6
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3005082) Progesterone [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
27.7
—
0
6
(4035726)
7
75
0.93
0.00
1.1
1.4
—
—
—
0
0
(4281824)
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
9
98
0.91
0.00
1.4
1.3
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
7
0.00
0.00
0.0
4.0
—
33.6
—
0
7
(3017704) Immunofixation for Urine
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
0.00
0.0
3.1
—
79.7
—
0
7
(3017569) Oxygen content in Arterial blood
0
6
0.00
0.00
0.0
12.8
—
—
—
0
0
(4062490)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum
0
6
0.00
0.00
0.0
1.7
—
17.6
—
0
6
(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(4211845)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3010503) CD19 cells [#/volume] in Blood
0
5
0.00
0.00
0.0
1.2
—
0.1
—
0
5
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
7
0.00
0.00
0.0
2.1
—
13.7
—
0
7
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
(3012565) Volume of 24 hour Urine
0
6
0.00
0.00
0.0
2.2
—
2208.3
—
0
6
(4024509)
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint ENTEROPATH_E_COLI and mortality.

Females

Parameter HR [95% CI] p-value
ENTEROPATH_E_COLI 2.339 [1.61, 3.41] < 0.001
Birth year 1.0 [0.99, 1.01] 0.938

During the follow-up period (1.1.1998 — 31.12.2019), 122 out of 367 females with ENTEROPATH_E_COLI died.

Males

Parameter HR [95% CI] p-value
ENTEROPATH_E_COLI 2.601 [1.56, 4.34] < 0.001
Birth year 0.982 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 334 males with ENTEROPATH_E_COLI died.

Mortality risk

Mortality risk for people of age

years, who have ENTEROPATH_E_COLI.

N-year risk Females Males
1 0.256% 0.401%
5 1.533% 2.463%
10 3.763% 6.297%
15 7.396% 12.017%
20 12.958% 19.635%

Relationships between endpoints

↥

Index endpoint: ENTEROPATH_E_COLI – Enteropathogenic Escherichia coli infection

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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