This is a non-core endpoint: only basic statistics are computed.
Disorders of glycosaminoglycan metabolism, other/unspecified
E4_GLUCOSAMINOGLYCNAS
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
8 |
4. Check minimum number of eventsNone |
8 |
5. Include endpointsNone |
8 |
6. Filter based on genotype QC (FinnGen only) |
8 |
Control definitions (FinnGen only)
- Control exclude
- E4_METABOLIA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Disorders of glycosaminoglycan metabolism, other/unspecified
based on the number of shared cases.
Similar with more cases:
- Disorders of glycosaminoglycan metabolism
- Metabolic disorders
- Hypertension, essential
- Hypertension
- Hypertensive diseases (excluding secondary)
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
Not enough data for upset plot.
Not enough data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 55 | 33 | 22 |
| Only index persons | 49 | 30 | 19 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | - | 72.05 | 54.26 |
| Only index persons | 68.41 | 71.51 | 63.53 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8 | 5 | - |
| Unadjusted period prevalence (%) | 0.00 | 0.00 | - |
| Median age at first event (years) | 70.91 | 70.97 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
0
17
0.00
0.46
0.0
3.8
—
24.0
—
0
11
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
0
14
0.00
0.46
0.0
2.1
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
0
14
0.00
0.46
0.0
1.2
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
0
10
0.00
0.23
0.0
1.9
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002256) Pathology report gross observation
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020891) Body temperature
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
(3027456) Digoxin [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
5.2
—
0.8
—
0
6
(3018405) Lactate [Moles/volume] in Arterial blood
0
6
0.00
0.00
0.0
2.3
—
1.1
—
0
6
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
0
6
0.00
0.00
0.0
2.2
—
1.2
—
0
6
(3008152) Bicarbonate [Moles/volume] in Arterial blood
0
6
0.00
0.00
0.0
4.5
—
20.5
—
0
6
(4010399)
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
0
6
0.00
0.00
0.0
1.3
—
3.0
—
0
6
(40761535) Cells panel - Urine sediment
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
4.7
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint E4_GLUCOSAMINOGLYCNAS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have E4_GLUCOSAMINOGLYCNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: E4_GLUCOSAMINOGLYCNAS – Disorders of glycosaminoglycan metabolism, other/unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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