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This is a non-core endpoint: only basic statistics are computed.

Ectopic hormone secretion, not elsewhere classified

E4_ECTHOR

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E34.2
  • Hospital discharge: ICD-9 2593
  • Cause of death: ICD-10 E34.2
  • Cause of death: ICD-9 2593

2 out of 7 registries used, show all original rules.

7

4. Check minimum number of events

None

7

5. Include endpoints

None

7

6. Filter based on genotype QC (FinnGen only)

7

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E34
Name in latin
Secretio hormonalis ectopica non alibi classificata

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 82 39 42
Only index persons 48 23 25
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 51.55 49.20 54.00
Only index persons 38.14 37.27 38.94

-FinnGen-

Key figures

All Female Male
Number of individuals 7 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 29.03 - -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
10
0.00
0.23
0.0
2.1
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
0
10
0.00
0.23
0.0
2.0
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
12
0.00
0.23
0.0
1.2
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
9
0.00
0.23
0.0
1.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
9
0.00
0.23
0.0
1.3
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
0
13
0.00
0.23
0.0
2.9
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
13.1
—
0
6
(1002224) Polysomnography panel
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003888) Timothy IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
10.3
—
0
5
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
0.9
—
0
7
(4010399)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40761535) Cells panel - Urine sediment
0
7
0.00
0.00
0.0
7.0
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
165.0
—
0
7
(40761536) Microorganisms panel - Urine sediment
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
6
0.00
0.00
0.0
4.3
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
6
0.00
0.00
0.0
4.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_ECTHOR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_ECTHOR.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: E4_ECTHOR – Ectopic hormone secretion, not elsewhere classified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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