Autoimmune polyglandular failure

E4_AUTOPOLYFAI

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

52

4. Check minimum number of events

None

52

5. Include endpoints

None

52

6. Filter based on genotype QC (FinnGen only)

52

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 302 189 110
Only index persons 247 161 86
Unadjusted period prevalence (%)
Whole population 0.00 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population 33.80 36.67 28.51
Only index persons 31.59 35.00 25.22

-FinnGen-

Key figures

All Female Male
Number of individuals 52 31 21
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 25.90 32.76 15.79

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3018418) pH of Serum or Plasma
36
98
9.69
14.93
29.8
3.4
ph
7.4
7.4
0.57
14
16
(3023368) Bacteria identified in Blood by Culture
31
85
7.55
12.28
7.1
4.6
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
32
93
7.35
11.86
6.5
3.1
mg/l
44.3
47.0
0.05
26
59
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
37
126
7.71
11.55
4.2
1.7
pmol/l
98.5
97.7
0.03
26
62
(3020682) Albumin/Creatinine [Ratio] in Urine
33
101
7.21
11.52
8.5
3.8
mg/mmol
10.0
9.0
0.07
26
62
(3021447) Carbon dioxide [Partial pressure] in Venous blood
16
23
9.60
11.28
7.7
11.7
kpa
5.9
5.7
0.30
16
23
(3012544) pH of Venous blood
16
24
9.19
10.88
6.1
12.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
15
22
9.18
10.34
9.8
11.5
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
38
143
7.16
10.33
11.3
5.1
g/l
34.7
36.7
2.01
38
137
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
39
151
7.33
10.25
37.9
9.4
mmol/l
1.1
1.2
3.06
39
138
(1616796) Gas panel - Central venous blood
13
6
28.12
9.93
8.3
1.3
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
34
123
6.10
9.43
9.8
6.9
inr
1.2
1.2
0.03
14
41
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
14
22
8.34
9.04
12.6
11.5
mmol/l
25.4
24.9
0.09
14
22
(3010838) Calcium [Moles/time] in 24 hour Urine
8
0
+∞
8.56
2.4
0.0
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
20
49
6.01
8.46
1.4
1.2
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
14
25
7.29
8.03
5.5
2.4
%
0.1
0.1
—
7
7
(3015377) Calcium [Moles/volume] in Serum or Plasma
30
109
5.14
7.97
6.7
3.6
mmol/l
2.2
2.3
1.77
30
99
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
30
111
5.02
7.74
2.0
1.5
u/ml
0.8
1.3
—
9
26
(3000494) Fungus identified in Specimen by Culture
17
41
5.67
7.20
2.1
1.9
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
14
28
6.47
7.17
5.6
2.3
%
1.4
0.6
—
7
7
(3027315) Oxygen [Partial pressure] in Blood
11
9
15.06
6.95
10.5
1.4
kpa
9.3
9.6
—
11
9
(3013290) Carbon dioxide [Partial pressure] in Blood
11
9
15.06
6.95
10.5
1.4
kpa
5.0
4.9
—
11
9
(3007164) IgA [Mass/volume] in Serum or Plasma
28
106
4.56
6.84
1.9
1.4
g/l
2.6
2.3
0.41
17
63
(3003181) Sodium [Moles/volume] in Urine
10
7
17.24
6.71
1.3
1.3
mmol/l
82.6
67.3
—
10
7
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
19
54
4.97
6.63
3.5
1.7
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
23
77
4.56
6.55
2.6
1.3
nmol/l
17.8
19.6
0.26
23
69
(3028271) Lactate [Moles/volume] in Capillary blood
9
5
21.28
6.52
3.0
1.6
mmol/l
2.0
1.3
—
9
5
(3012565) Volume of 24 hour Urine
6
0
+∞
6.37
3.0
0.0
ml
3293.3
—
—
6
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
11
20
6.71
6.10
1.6
1.1
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
12
24
6.20
6.08
6.1
2.5
%
0.0
0.0
—
5
6
(3013826) Glucose [Moles/volume] in Serum or Plasma
42
233
5.17
5.81
13.8
7.0
mmol/l
8.8
6.6
3.22
42
217
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
28
122
3.81
5.34
8.3
2.4
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
7
5
15.84
4.72
11.3
1.0
%
59.1
64.2
—
7
5
(3022806) Fractional oxyhemoglobin in Capillary blood
7
5
15.84
4.72
2.6
1.4
%
92.4
91.0
—
7
5
(3007853) Bacteria identified in Skin by Aerobe culture
13
35
4.62
4.71
3.9
1.7
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
8
9
10.23
4.45
8.1
8.6
mmol/l
24.0
23.3
—
8
9
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
6
13.19
4.41
3.4
1.2
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
7
6
13.19
4.41
3.4
1.3
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
12
32
4.58
4.37
4.4
3.3
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
8
10
9.20
4.23
8.9
4.6
%
66.7
64.4
—
8
10
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
13
38
4.23
4.22
2.8
1.7
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
28
141
3.14
3.96
4.3
3.0
ng/l
20.8
20.7
0.00
20
77
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
7
8
9.87
3.90
3.4
1.3
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
8
9.87
3.90
3.4
1.3
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
6
5
13.30
3.86
10.2
1.0
e9/l
4.2
5.7
—
6
5
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
6
5
13.30
3.86
1.5
2.8
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
12
36
4.03
3.74
2.9
1.5
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
26
130
3.00
3.66
11.1
6.7
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
6
6
11.07
3.59
3.3
1.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
21
94
3.07
3.57
7.2
2.3
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
9
18
5.80
3.55
1.7
1.7
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
22
102
3.01
3.51
7.3
2.4
e6/l
39.2
643.4
0.47
22
78
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
8
14
6.53
3.49
6.4
12.4
%
1.8
1.1
—
8
14
(3004119) Hemoglobin [Mass/volume] in Venous blood
8
14
6.53
3.49
7.4
17.4
g/l
119.7
125.9
—
8
14
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
7
9.48
3.35
4.0
1.3
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
7
9.48
3.35
4.0
1.3
—
—
—
0
0
(3019225) pH of Specimen
9
21
4.95
3.16
12.1
3.4
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
6
8
8.28
3.14
1.5
4.6
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
6
8
8.28
3.14
1.7
1.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
7
12
6.55
3.13
2.3
1.7
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
10
30
3.89
3.08
1.6
2.7
u/l
229.1
241.6
—
10
30
(3002173) Hemoglobin [Mass/volume] in Arterial blood
10
30
3.89
3.08
13.7
25.3
g/l
118.1
129.8
—
10
30
(3014007) Fractional oxyhemoglobin in Arterial blood
8
18
5.05
2.93
12.4
12.6
%
93.6
91.8
—
8
18
(40758558) Short blood count panel - Blood
20
97
2.73
2.86
3.3
7.4
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
5
6
9.04
2.81
1.0
1.0
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
26
145
2.59
2.81
3.4
3.0
u/l
42.9
32.7
0.66
26
140
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
8
20
4.53
2.69
12.4
11.3
%
0.6
0.8
—
8
20
(3024928) Oxygen saturation in Venous blood
5
7
7.74
2.60
2.0
24.1
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
7
7.74
2.60
1.4
1.0
—
—
—
0
0
(3019060) Gas panel - Arterial blood
8
21
4.30
2.58
14.1
26.3
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
8
21
4.30
2.58
12.4
10.9
%
1.5
1.8
—
8
21
(3013512) EKG study
19
94
2.61
2.58
4.5
3.0
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
6
12
5.49
2.47
2.3
2.3
ng/l
191.7
143.6
—
6
12
(3018405) Lactate [Moles/volume] in Arterial blood
6
12
5.49
2.47
11.8
1.8
mmol/l
1.4
1.8
—
6
12
(3018095) Leukocytes [#/volume] in Urine
23
127
2.45
2.47
7.5
3.1
e6/l
17.6
31.5
0.32
23
85
(40760892) CBC W Ordered Manual Differential panel - Blood
21
113
2.44
2.37
10.4
3.3
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
6
13
5.06
2.34
1.8
1.2
ug/l
1.5
0.2
—
6
13
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
7
19
4.09
2.24
20.7
3.6
mmol/l
25.5
25.8
—
7
19
(3044640) Blood type and Crossmatch panel - Blood
21
117
2.33
2.16
3.2
2.3
—
—
—
0
0
(40761535) Cells panel - Urine sediment
8
27
3.31
2.03
6.1
3.4
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
10
40
2.86
1.97
10.5
3.1
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
19
105
2.28
1.97
4.8
2.6
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
16
82
2.37
1.96
3.2
2.4
—
—
—
0
0
(3022145) Colonoscopy Study observation
11
47
2.70
1.93
1.4
1.2
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
10
41
2.78
1.88
1.7
1.3
—
—
—
0
0
(3020891) Body temperature
5
12
4.48
1.87
14.6
1.9
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
7
24
3.20
1.79
1.7
1.1
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
13
4.13
1.75
1.2
1.0
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
5
13
4.13
1.75
2.8
1.9
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
13
4.13
1.75
4.0
2.0
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
11
50
2.52
1.71
4.3
3.1
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
20
119
2.11
1.70
7.1
3.3
estimate
0.0
0.0
0.00
11
41
(3022313) Gas panel - Capillary blood
6
20
3.25
1.63
23.7
3.3
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
5
15
3.57
1.56
4.0
1.3
nmol/l
52.8
33.1
—
5
15
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
26
175
1.97
1.56
4.1
5.0
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
5
16
3.34
1.47
3.8
1.7
%
79.2
89.1
—
5
16
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
5
17
3.14
1.39
1.6
1.7
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
34
0.00
1.21
0.0
1.5
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
36
290
1.78
1.07
7.7
4.0
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
5
22
2.40
1.06
1.2
1.0
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
14
87
1.83
1.00
1.8
1.5
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
28
2.29
0.95
1.2
1.0
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
9
52
1.88
0.82
2.3
2.5
umol/l
6.0
4.4
—
9
46
(3021601) Nitrite [Presence] in Urine by Test strip
27
213
1.56
0.78
8.1
4.5
estimate
0.0
0.0
0.00
11
40
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
5
94
0.48
0.75
1.4
2.4
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
13
86
1.68
0.75
4.9
3.7
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
23
177
1.54
0.73
7.0
3.1
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
27
216
1.52
0.71
7.0
3.3
estimate
0.0
0.1
—
10
38
(3035350) Ketones [Presence] in Urine by Test strip
27
216
1.52
0.71
7.0
3.2
estimate
0.0
0.0
0.00
11
42
(4035726)
5
29
1.80
0.65
2.0
1.1
—
—
—
0
0
(3015736) pH of Urine
22
172
1.48
0.63
5.6
3.0
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
5
85
0.54
0.63
1.2
2.2
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
20
0.00
0.62
0.0
1.3
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
20
0.00
0.62
0.0
1.3
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
19
0.00
0.61
0.0
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
22
0.00
0.61
0.0
1.3
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
22
0.00
0.61
0.0
1.3
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
22
0.00
0.61
0.0
1.5
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
22
0.00
0.61
0.0
1.3
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
22
0.00
0.61
0.0
1.3
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
23
0.00
0.60
0.0
1.7
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
12
83
1.58
0.58
5.2
4.3
ug/l
0.9
1.9
1.53
12
73
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
12
83
1.58
0.58
1.3
1.3
u/ml
0.9
2.1
—
5
43
(3000492) Spirometry study
6
37
1.70
0.58
1.8
1.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
7
49
1.49
0.48
24.0
6.7
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
14
178
0.71
0.44
6.0
2.6
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
9
124
0.67
0.41
1.8
2.1
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
17
136
1.37
0.40
7.1
2.6
—
—
—
0
0
(3044889) 12 lead EKG panel
31
274
1.33
0.38
5.8
3.0
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
8
106
0.71
0.33
1.4
1.6
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
39
417
0.74
0.32
27.6
14.4
%
38.7
41.2
2.20
28
342
(40768804) Tissue Pathology biopsy report
19
164
1.25
0.25
2.2
1.8
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
9
114
0.75
0.23
1.6
1.7
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3010726) Horse dander IgE Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.0
—
3.2
—
0
5
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.1
—
1.9
—
0
8
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
37
349
1.21
0.18
3.6
3.7
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
5
69
0.70
0.18
1.6
2.0
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
11
94
1.22
0.14
1.7
1.7
—
—
—
0
0
(3002256) Pathology report gross observation
5
45
1.12
0.10
1.0
1.1
—
—
—
0
0
(3018301) Testosterone Free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
35.4
—
0
7
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027456) Digoxin [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.6
—
0.7
—
0
5
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
12.1
—
1219.6
—
0
9
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
9.9
—
712.9
—
0
9
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
102.6
—
0
5
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
0.9
—
0
5
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
7
70
1.00
0.00
1.7
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_AUTOPOLYFAI and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_AUTOPOLYFAI.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: E4_AUTOPOLYFAI – Autoimmune polyglandular failure

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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