Other adrenocortical overactivity

E4_ADREACT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E27.0
  • Hospital discharge: ICD-9 2553A
  • Hospital discharge: ICD-8 25508
  • Cause of death: ICD-10 E27.0
  • Cause of death: ICD-9 2553A
  • Cause of death: ICD-8 25508

2 out of 7 registries used, show all original rules.

219

4. Check minimum number of events

None

219

5. Include endpoints

None

219

6. Filter based on genotype QC (FinnGen only)

219

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E27
Name in latin
Alia hyperfunctio adrenocorticalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4574 3566 1002
Only index persons 3335 2615 720
Unadjusted period prevalence (%)
Whole population 0.09 0.10 0.03
Only index persons 0.08 0.10 0.03
Median age at first event (years)
Whole population 7.91 7.69 8.52
Only index persons 8.08 7.85 8.90

-FinnGen-

Key figures

All Female Male
Number of individuals 219 183 36
Unadjusted period prevalence (%) 0.05 0.06 0.02
Median age at first event (years) 14.57 8.40 45.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
191
Matched controls
1911
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E27.0
ICD-10 Finland
Other adrenocortical overactivity
+∞
239.3
176
*
H02AB09
ATC
hydrocortisone; systemic
24.6
35.1
50
27
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
27.8
26
*
H02AA02
ATC
fludrocortisone; oral
+∞
22.3
21
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
22.3
21
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
13.1
18.6
33
30
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
+∞
15.8
15
*
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
173.6
15.7
16
*
E30.1
ICD-10 Finland
Precocious puberty
+∞
12.6
12
*
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
138.7
12.6
13
*
25508
ICD-8 Finland
Diseases of adrenal glands, Hyperfunctio adrenocorticalis alia
+∞
11.6
11
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
8.5
9.4
20
26
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
52.4
8.8
10
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.2
8.4
22
39
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
+∞
8.4
8
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
+∞
8.4
8
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.9
7.4
48
197
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
7.3
7
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
+∞
7.3
7
*
E34.45
ICD-10 Finland
Abnormal growth increase
+∞
7.3
7
*
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
+∞
7.3
7
*
M05BA04
ATC
alendronic acid; oral
7.3
6.7
15
22
H02AB07
ATC
prednisone; oral
4.1
6.4
24
65
E27.2
ICD-10 Finland
Addisonian crisis
+∞
6.3
6
*
E24.8
ICD-10 Finland
Other Cushing syndrome
+∞
6.3
6
*
E66.01
ICD-10 Finland
Obesity due to excess calories
3.7
6.0
25
74
H03AA01
ATC
levothyroxine sodium; systemic
2.7
6.0
44
193
C03CA01
ATC
furosemide; systemic
3.2
6.0
31
109

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3035637) Corticotropin [Mass/volume] in Plasma
36
28
15.19
38.37
2.3
1.8
—
—
—
0
0
(3009214) Lutropin [Units/volume] in Serum or Plasma
39
101
4.48
14.23
2.3
1.6
u/l
10.5
7.3
0.53
21
66
(3023323) Follitropin [Units/volume] in Serum or Plasma
41
111
4.31
14.13
2.0
1.5
iu/l
15.6
15.7
0.01
22
79
(3023368) Bacteria identified in Blood by Culture
57
302
2.20
5.69
6.9
4.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
66
378
2.07
5.36
7.8
3.7
ph
7.4
7.4
0.37
18
67
(1616796) Gas panel - Central venous blood
12
26
4.82
5.32
8.3
3.2
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
16
44
3.84
5.31
1.3
1.3
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
29
116
2.73
5.30
3.4
3.3
pmol/l
5.0
4.9
0.24
29
103
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
45
228
2.23
4.97
2.7
2.0
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
95
645
1.84
4.54
7.6
7.3
—
—
—
0
0
(4035726)
26
107
2.62
4.50
1.5
1.5
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
72
449
1.90
4.49
5.1
3.2
mmol/l
2.4
2.4
0.92
64
395
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
100
695
1.81
4.39
3.6
2.6
nmol/l
72.5
71.3
0.17
94
627
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
33
159
2.27
4.08
2.8
1.9
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
191
1651
2.23
3.93
6.1
4.2
mu/l
1.9
1.8
0.54
179
1536
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
32
156
2.23
3.85
2.8
1.9
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
127
975
1.72
3.74
7.6
7.1
e9/l
0.2
0.2
0.41
111
852
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
101
729
1.72
3.73
11.4
8.2
mmol/l
1.2
1.2
0.18
88
647
(3001604) Monocytes [#/volume] in Blood
123
942
1.70
3.61
7.1
6.7
e9/l
0.6
0.5
1.73
108
808
(3025941) Bacteria identified in Stool by Culture
23
101
2.43
3.50
1.5
1.2
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
21
89
2.50
3.44
11.9
2.6
mmol/l
1.2
1.2
0.98
21
80
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
14
48
3.05
3.36
1.6
1.4
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
14
48
3.05
3.36
1.6
1.4
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
122
944
1.66
3.35
7.1
6.7
e9/l
0.0
0.0
0.71
107
808
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
72
486
1.72
3.32
1.9
1.6
pmol/l
91.1
95.4
0.35
39
245
(3019198) Lymphocytes [#/volume] in Blood
126
986
1.65
3.28
6.9
6.6
e9/l
2.5
2.2
0.48
112
868
(3031309) Prolactin monomeric/Prolactin.total in Serum or Plasma
6
7
8.77
3.28
2.3
1.0
%
75.5
74.1
—
6
7
(21491979) Prolactin monomeric [Units/volume] in Serum or Plasma
6
7
8.77
3.28
2.3
1.0
mu/l
478.8
284.6
—
6
7
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
169
1432
1.79
3.24
5.8
3.7
pmol/l
14.3
14.3
0.06
153
1302
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
95
695
1.65
3.21
7.6
6.0
umol/l
12.3
12.5
0.02
88
647
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
15
56
2.80
3.13
1.7
1.2
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
10
29
3.57
3.08
9.5
2.4
kpa
8.7
9.7
—
10
29
(3013290) Carbon dioxide [Partial pressure] in Blood
10
29
3.57
3.08
9.6
2.4
kpa
5.0
4.7
—
10
29
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
8
16
5.15
3.08
11.3
3.7
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
31
165
2.02
3.00
1.2
1.3
—
—
—
0
0
(3044889) 12 lead EKG panel
116
905
1.60
2.94
3.2
2.8
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
15
58
2.70
2.94
1.7
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
15
59
2.66
2.85
1.7
1.2
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
11
36
3.16
2.85
1.5
1.3
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
8
18
4.57
2.82
1.9
2.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
7
14
5.13
2.75
1.1
1.3
nmol/l
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
92
688
1.58
2.74
11.4
7.8
mmol/l
1.2
1.2
0.68
87
641
(3021440) Promyelocytes/100 leukocytes in Blood
22
106
2.20
2.74
3.9
4.8
%
0.0
0.1
—
8
25
(3006504) Eosinophils/100 leukocytes in Blood
114
899
1.56
2.67
7.5
6.7
%
2.6
2.8
0.18
109
843
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
7
15
4.78
2.62
2.0
2.1
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
8
20
4.11
2.59
2.0
1.8
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
32
182
1.89
2.57
1.6
1.4
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
6
11
5.57
2.56
1.2
1.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
58
394
1.64
2.54
3.0
2.5
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
132
1084
1.55
2.53
10.2
8.5
e9/l
4.3
3.8
1.67
116
920
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
34
199
1.84
2.50
8.4
6.9
mmol/l
1.9
0.8
1.64
26
151
(3001684) Respiratory syncytial virus Ag [Presence] in Specimen
7
16
4.48
2.49
1.4
1.0
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
7
16
4.48
2.49
1.1
1.3
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
8
21
3.91
2.49
1.9
1.9
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
56
379
1.64
2.48
3.4
3.1
ng/l
34.9
26.3
0.22
34
188
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
32
185
1.85
2.45
1.2
1.3
iu/ml
364.4
124.0
—
8
70
(3006922) Hepatitis E virus Ab [Presence] in Serum
6
12
5.11
2.42
1.0
1.1
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
22
112
2.07
2.40
8.0
7.8
kpa
14.2
14.1
0.02
22
107
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
22
112
2.07
2.40
7.9
7.8
kpa
5.5
5.1
0.67
22
107
(3025159) Blasts/100 leukocytes in Blood
21
105
2.11
2.40
4.0
4.8
%
0.0
0.0
—
8
21
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
51
340
1.65
2.39
2.5
3.1
mg/l
0.9
1.4
0.58
34
236
(3021901) Oxygen saturation in Capillary blood
8
22
3.73
2.39
5.2
3.9
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
13
53
2.54
2.32
2.2
2.9
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
6
13
4.71
2.28
1.3
2.0
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
6
13
4.71
2.28
1.3
2.0
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
6
13
4.71
2.28
1.3
2.0
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
162
1408
1.58
2.28
3.8
3.2
mmol/l
5.6
5.6
0.16
151
1287
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
7
18
3.98
2.27
1.1
1.3
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
9
29
3.19
2.25
1.0
1.0
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
132
1100
1.50
2.24
10.9
6.0
u/l
91.6
86.4
0.39
125
1022
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
81
613
1.51
2.19
4.8
3.4
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
21
109
2.02
2.19
3.7
4.4
%
0.4
0.5
—
7
21
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
9
30
3.08
2.17
2.0
1.8
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
23
124
1.96
2.17
1.3
1.3
miu/ml
288.7
293.6
—
10
60
(3017181) Myelocytes/100 leukocytes in Blood
22
117
1.98
2.15
4.0
4.5
%
0.5
0.7
—
8
30
(3019060) Gas panel - Arterial blood
12
49
2.53
2.14
3.7
5.2
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
12
49
2.53
2.14
1.3
1.0
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
12
49
2.53
2.14
1.3
1.0
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
18
89
2.11
2.13
3.0
1.7
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
14
280
0.47
2.09
1.6
1.5
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
38
243
1.68
2.08
3.8
4.2
ng/l
885.6
765.2
0.13
31
192
(3019309) Folate [Moles/volume] in Red Blood Cells
28
164
1.81
2.07
1.5
1.6
nmol/l
1346.0
1038.6
0.89
23
125
(3034770) Mitochondria Ab [Titer] in Serum
10
38
2.71
2.04
1.1
1.6
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
15
70
2.23
2.03
1.7
1.7
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
25
142
1.86
2.03
1.7
1.3
u/ml
173.2
380.9
0.63
25
134
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
9
32
2.89
2.02
1.8
1.3
—
—
—
0
0
(3026782) Osmolality of Urine
52
363
1.57
2.01
4.8
2.7
mosm/kgh2o
591.1
576.2
0.17
46
318
(3030467) Casts [#/volume] in Urine by Automated count
70
522
1.50
2.01
5.0
3.3
e6/l
0.3
0.3
0.19
57
381
(36304419) Bacteria [Presence] in Urine
70
524
1.49
1.97
5.0
3.2
—
—
—
0
0
(3002222) Hepatitis E virus IgM Ab [Presence] in Serum
5
11
4.62
1.95
1.0
1.0
—
—
—
0
0
(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay
5
11
4.62
1.95
1.0
1.0
—
—
—
0
0
(4062490)
6
16
3.82
1.95
1.7
1.3
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
32
199
1.71
1.94
3.4
2.4
mmol/l
2.5
2.4
0.91
27
164
(3000850) Epithelial cells [#/volume] in Urine
54
385
1.53
1.90
4.4
2.5
e6/l
8.4
8.5
0.02
48
339
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
15
73
2.13
1.85
1.7
1.3
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
8
29
2.82
1.81
1.0
1.1
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
12
54
2.29
1.77
4.6
3.8
%
43.5
53.0
0.44
12
54
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
6
145
0.40
1.72
1.2
1.6
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
14
69
2.10
1.68
2.6
1.6
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
124
1056
1.40
1.67
3.2
3.0
u/l
37.8
30.9
0.75
119
1006
(3016018) Differential panel - Cerebral spinal fluid
7
25
2.86
1.66
2.1
3.6
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
66
505
1.44
1.63
3.3
2.5
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
146
1284
1.41
1.60
3.4
3.1
mmol/l
1.3
1.2
1.41
139
1204
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
63
480
1.44
1.59
2.2
2.4
mg/l
2.7
2.7
0.11
58
412
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
137
1193
1.40
1.58
5.4
4.0
mmol/mol
37.9
38.0
0.04
131
1120
(40758558) Short blood count panel - Blood
65
499
1.43
1.57
10.4
7.5
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
5
15
3.39
1.53
1.4
1.4
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
5
15
3.39
1.53
1.4
1.4
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
5
15
3.39
1.53
1.4
1.4
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
5
15
3.39
1.53
1.4
1.4
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
6
21
2.91
1.51
1.0
1.0
—
—
—
0
0
(3000991) Gas panel - Venous blood
32
214
1.58
1.49
9.3
8.7
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
34
231
1.56
1.48
1.4
1.5
titre
514.3
400.9
—
7
47
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
5
16
3.17
1.44
1.4
1.4
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
5
16
3.17
1.44
1.4
1.4
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
6
22
2.77
1.44
1.3
2.1
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
6
22
2.77
1.44
1.2
1.1
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
10
46
2.23
1.42
2.7
2.1
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
12
60
2.06
1.41
2.1
2.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
72
573
1.38
1.40
5.0
3.2
e6/l
77.5
55.3
0.19
58
429
(3045683) HLA typing for celiac disease panel - Blood or Tissue
5
17
2.98
1.36
1.2
1.0
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
58
447
1.40
1.36
3.8
3.2
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
11
54
2.09
1.35
1.6
1.3
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
104
886
1.33
1.29
11.4
8.6
e9/l
0.0
0.0
0.00
86
702
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
8
35
2.33
1.28
1.1
1.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
58
452
1.39
1.27
6.0
5.2
inr
1.1
1.1
0.12
21
138
(3007164) IgA [Mass/volume] in Serum or Plasma
76
619
1.35
1.27
1.7
1.5
g/l
1.8
1.9
0.35
43
335
(3003694) ABO and Rh group [Type] in Blood
53
672
0.72
1.26
1.5
1.8
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
9
45
2.04
1.25
2.9
2.3
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
33
233
1.49
1.22
3.4
6.2
s
30.5
30.2
0.11
33
227
(3026389) Candida sp identified in Specimen by Organism specific culture
6
26
2.34
1.19
1.3
1.1
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
11
57
1.98
1.19
2.0
2.0
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
179
1664
1.41
1.17
22.1
13.4
%
13.6
13.3
2.02
172
1632
(3004789) Transferrin [Mass/volume] in Serum or Plasma
29
201
1.51
1.17
4.0
2.6
g/l
2.3
2.5
1.26
29
182
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
5
113
0.43
1.16
1.2
1.5
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
5
20
2.53
1.15
1.2
1.5
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
5
20
2.53
1.15
4.2
1.8
%
92.1
93.7
—
5
20
(3018095) Leukocytes [#/volume] in Urine
83
694
1.32
1.14
5.7
3.8
e6/l
17.8
66.8
2.92
60
456
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
11
58
1.94
1.14
10.4
10.2
—
—
—
0
0
(40761535) Cells panel - Urine sediment
16
96
1.72
1.13
3.0
3.4
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
8
40
2.04
1.13
5.6
3.4
%
53.9
54.4
—
8
40
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
14
81
1.78
1.12
1.3
1.4
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
5
21
2.41
1.09
2.6
3.4
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
13
74
1.80
1.09
1.4
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
68
556
1.32
1.09
3.6
2.4
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
28
196
1.49
1.09
3.0
1.7
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
7
32
2.23
1.09
3.0
10.5
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
148
1344
1.31
1.08
3.7
3.2
mmol/l
1.4
1.5
0.92
141
1254
(3021601) Nitrite [Presence] in Urine by Test strip
102
883
1.29
1.07
6.4
4.8
estimate
0.0
0.0
0.00
22
187
(3031040) Bacteria [#/volume] in Urine by Automated count
136
1223
1.30
1.06
5.3
4.0
—
264.9
—
0
16
(3038177) Helicobacter pylori Ab [Presence] in Serum
7
34
2.09
1.04
1.0
1.1
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
9
47
1.95
1.03
1.9
3.1
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
32
233
1.44
1.03
1.5
1.6
%
1.5
1.4
0.59
27
213
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
149
1360
1.30
1.01
3.9
3.3
mmol/l
4.4
4.6
1.10
143
1278
(40768793) Breast Pathology biopsy report
7
35
2.03
1.01
1.3
1.3
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
102
890
1.27
0.99
4.9
3.4
estimate
0.0
0.0
0.00
22
182
(4306422)
5
23
2.20
0.98
1.2
1.0
—
—
—
0
0
(3022313) Gas panel - Capillary blood
25
175
1.48
0.98
9.1
6.9
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
190
1799
1.42
0.98
20.1
10.7
mg/l
21.1
22.3
0.24
150
1327
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
149
1364
1.29
0.97
4.1
3.5
mmol/l
2.6
2.7
0.86
143
1269
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
48
595
0.75
0.96
2.1
2.4
—
—
—
0
0
(40768443) Skin Pathology biopsy report
9
51
1.80
0.96
1.1
1.1
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
37
281
1.38
0.95
5.4
4.0
mg/mmol
14.3
16.3
0.10
28
192
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
52
1.76
0.93
1.4
1.3
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
32
238
1.40
0.93
5.7
7.6
mmol/l
1.4
1.4
0.00
22
191
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
6
28
2.17
0.92
1.5
1.9
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
40
310
1.36
0.91
2.1
2.8
ug/g
136.9
86.3
0.54
27
238
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
7
130
0.52
0.91
1.4
1.7
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
6
29
2.10
0.90
1.7
4.3
—
—
—
0
0
(44790047)
6
29
2.10
0.90
1.3
2.3
—
—
—
0
0
(44806118)
6
29
2.10
0.90
1.3
2.3
—
—
—
0
0
(44790048)
6
29
2.10
0.90
1.3
2.3
—
—
—
0
0
(44790049)
6
29
2.10
0.90
1.3
2.3
—
—
—
0
0
(3020891) Body temperature
8
42
1.94
0.89
7.0
4.8
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
30
223
1.40
0.88
4.0
2.6
umol/l
12.2
14.2
0.70
30
210
(3019832) Treponema pallidum Ab [Presence] in Serum
39
492
0.75
0.87
1.7
1.8
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
101
890
1.25
0.87
4.9
3.3
estimate
0.0
0.0
0.00
22
180
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
79
677
1.26
0.87
1.6
1.7
u/ml
0.9
2.9
1.48
16
155
(3017143) Hepatitis C virus Ab [Presence] in Serum
41
322
1.34
0.86
1.8
1.5
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
30
224
1.39
0.86
11.9
10.6
mmol/l
24.5
24.8
0.20
30
224
(40768804) Tissue Pathology biopsy report
65
545
1.27
0.85
2.2
1.8
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
26
190
1.42
0.84
3.5
1.9
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
137
1253
1.25
0.84
5.0
3.7
mm/h
12.5
8.9
2.06
128
1148
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
15
97
1.59
0.84
1.3
1.5
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
146
1345
1.26
0.83
19.3
8.4
ml/min/173m2
96.1
98.0
0.34
120
1008
(1002224) Polysomnography panel
8
46
1.77
0.83
1.1
1.2
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
35
270
1.35
0.83
4.1
3.5
mg/l
98.2
118.5
0.16
29
186
(3029937) Albumin [Presence] in Urine by Test strip
57
472
1.28
0.82
5.8
3.3
estimate
0.1
0.0
0.48
22
186
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
40
316
1.33
0.81
3.3
3.1
e6/l
2.2
4.5
1.26
21
161
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
13
82
1.62
0.80
1.7
2.8
ml/min/173m2
68.0
85.8
—
6
31
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
10
59
1.73
0.77
1.4
1.9
—
—
—
0
0
(3015736) pH of Urine
82
715
1.23
0.76
4.3
3.2
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
86
755
1.23
0.75
2.5
2.0
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
24
177
1.40
0.74
9.8
6.7
mmol/l
24.3
24.1
0.12
24
177
(3022145) Colonoscopy Study observation
17
117
1.49
0.74
1.6
1.3
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
9
56
1.63
0.73
1.7
1.1
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
7
40
1.77
0.72
3.3
3.3
e9/l
3.5
4.1
—
7
40
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
5
26
1.94
0.71
3.8
2.0
—
—
—
0
0
(3019225) pH of Specimen
16
110
1.49
0.70
4.1
4.3
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
11
69
1.63
0.70
13.9
9.4
%
95.8
94.5
0.88
11
69
(3049717) Cytology report of Urine Cyto stain
5
27
1.87
0.69
1.4
2.3
—
—
—
0
0
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
32
252
1.32
0.67
2.7
2.3
u/l
3707.3
6002.0
0.25
12
98
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
7
43
1.65
0.67
1.7
1.9
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
5
28
1.80
0.66
1.4
1.5
—
—
—
0
0
(3002256) Pathology report gross observation
21
155
1.39
0.66
1.3
1.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
22
164
1.38
0.65
1.5
1.6
—
—
—
0
0
(3000492) Spirometry study
19
139
1.40
0.63
1.6
1.4
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
0
20
0.00
0.60
0.0
2.0
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
74
653
1.20
0.60
5.2
3.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
32
257
1.29
0.59
1.3
1.2
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
54
625
0.82
0.59
2.5
2.6
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
6
35
1.73
0.58
4.0
1.9
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
10
65
1.56
0.56
1.1
1.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
39
324
1.25
0.56
3.2
3.0
e6/l
1.1
1.0
0.07
20
168
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
6
37
1.64
0.56
1.3
1.3
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
11
157
0.68
0.53
1.2
1.2
—
—
—
0
0
(4010399)
14
100
1.43
0.53
1.6
1.4
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
60
679
0.84
0.52
2.4
2.2
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
13
93
1.42
0.49
1.2
1.8
—
—
—
0
0
(3003338) MCHC [Mass/volume]
177
1703
1.21
0.47
21.9
13.8
g/l
332.1
332.9
0.55
171
1689
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
29
238
1.25
0.47
3.8
2.9
ng/l
171.8
272.5
0.27
16
133
(3011288) Drugs identified in Urine by Screen method
20
156
1.31
0.47
3.4
3.0
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
31
257
1.24
0.46
1.3
1.2
u/ml
1.4
9.7
—
8
105
(3019150) Specific gravity of Urine by Refractometry
47
409
1.19
0.44
3.8
3.1
kg/l
1.0
1.0
0.77
12
57
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
15
113
1.35
0.44
3.2
2.5
—
—
—
0
0
(3013512) EKG study
37
315
1.21
0.44
3.4
2.9
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
20
158
1.29
0.43
10.8
3.4
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
13
96
1.38
0.42
13.1
13.3
mg/l
1.2
1.1
0.39
13
89
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
1.3
—
127.2
—
0
15
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(4027681)
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3024474) Albumin [Mass/volume] in Cerebral spinal fluid
0
17
0.00
0.41
0.0
1.1
—
224.8
—
0
17
(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
5
34
1.48
0.40
1.6
4.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
34
396
0.83
0.40
1.6
1.5
—
—
—
0
0
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
0
18
0.00
0.40
0.0
3.1
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
22
179
1.25
0.39
1.8
1.3
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
22
179
1.25
0.39
1.2
1.6
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
86
794
1.14
0.38
4.5
4.0
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
9
69
1.32
0.37
1.3
1.5
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
14
178
0.77
0.36
1.6
1.4
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
39
442
0.86
0.34
2.4
2.1
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
12
91
1.34
0.34
1.6
1.6
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
6
47
1.28
0.32
1.3
1.9
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
6
47
1.28
0.32
1.2
2.0
—
—
—
0
0
(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum
7
53
1.33
0.31
1.0
1.1
—
0.2
—
0
18
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
7
54
1.31
0.30
3.0
2.5
nmol/l
0.6
0.5
—
7
45
(3037467) Urinalysis macro (dipstick) panel - Urine
132
1263
1.11
0.30
6.6
4.1
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
47
424
1.14
0.29
5.4
4.2
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
33
373
0.86
0.29
2.2
1.9
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
21
177
1.21
0.28
1.6
2.0
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
10
76
1.33
0.28
1.5
1.7
—
—
—
0
0
(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma
10
78
1.30
0.24
1.5
1.7
—
105.7
—
0
7
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
15
124
1.23
0.24
2.3
2.2
—
18.8
—
0
6
(3007461) Platelets [#/volume] in Blood
208
2054
1.25
0.24
26.3
15.6
e9/l
269.1
265.3
0.37
202
1989
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
29
257
1.15
0.23
1.3
1.2
iu/ml
52.9
19.9
—
7
67
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
10
125
0.79
0.23
1.1
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
54
499
1.11
0.23
2.2
2.1
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
18
210
0.84
0.23
3.3
2.3
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
10
79
1.28
0.22
1.5
1.7
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
18
209
0.85
0.22
3.3
2.3
—
—
—
0
0
(4281824)
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
10
0.00
0.21
0.0
1.4
—
5.8
—
0
10
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3020491) Glucose [Moles/volume] in Blood
0
10
0.00
0.21
0.0
1.6
—
5.7
—
0
10
(3024471) HLA-A [Type]
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
(3024932) HLA-DR beta [Type]
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3042733) HLA Ab [Presence] in Serum
0
12
0.00
0.21
0.0
2.1
—
—
—
0
0
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
6
48
1.26
0.20
3.8
2.6
g/l
1.7
1.3
—
6
42
(3022621) pH of Urine by Test strip
9
115
0.77
0.20
1.8
2.2
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(3009991) Angiotensin converting enzyme [Enzymatic activity/volume] in Cerebral spinal fluid
0
14
0.00
0.20
0.0
1.1
—
1.0
—
0
8
(4211845)
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
18
207
0.86
0.20
3.3
2.3
—
—
—
0
0
(3003888) Timothy IgE Ab [Units/volume] in Serum
11
90
1.23
0.19
1.0
1.2
u/ml
5.5
6.4
—
5
66
(3000764) Benzodiazepines [Presence] in Urine
18
206
0.86
0.19
3.3
2.3
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
7
62
1.13
0.17
1.4
1.4
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
23
206
1.13
0.16
1.0
1.1
—
—
—
0
0
(3026361) Erythrocytes [#/volume] in Blood
208
2060
1.19
0.16
26.1
15.5
e12/l
4.6
4.5
1.54
201
1988
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
13
151
0.85
0.16
1.5
1.6
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
8
73
1.10
0.16
1.0
1.2
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
191
1884
1.11
0.15
16.0
9.1
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
13
149
0.86
0.14
1.2
1.2
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
208
2062
1.17
0.14
26.2
15.5
e9/l
7.5
6.8
2.71
200
1989
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
11
94
1.18
0.13
1.1
1.2
—
—
—
0
0
(3008898) HLA-B27 [Presence]
9
105
0.85
0.13
1.1
1.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
181
1785
1.08
0.13
20.8
12.3
%
39.3
39.2
0.09
155
1506
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
11
127
0.86
0.13
1.5
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
11
127
0.86
0.13
1.5
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
11
127
0.86
0.13
1.5
1.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
11
127
0.86
0.13
1.5
1.4
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
20
181
1.12
0.12
1.1
1.3
—
93.9
—
0
9
(3047007) Chlamydophila sp Ab [Presence] in Serum
5
44
1.14
0.10
1.2
1.2
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
5
46
1.09
0.09
1.8
1.2
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
47
1.07
0.09
1.2
1.1
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
56
540
1.05
0.08
2.0
1.7
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
18
194
0.92
0.07
3.2
2.4
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
9
85
1.06
0.07
1.2
1.4
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
17
158
1.08
0.06
6.4
5.2
ug/l
5.2
1.9
0.53
17
136
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
12
131
0.91
0.06
6.6
4.9
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
51
495
1.04
0.05
5.5
2.8
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
11
120
0.91
0.05
4.7
5.1
%
27.2
22.5
—
6
61
(3001019) Free T4 and TSH panel - Serum or Plasma
11
101
1.09
0.04
1.2
1.3
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
11
117
0.94
0.02
2.4
2.7
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
44
433
1.02
0.01
1.7
1.7
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
11
104
1.06
0.01
1.4
1.5
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
10
102
0.98
0.00
1.4
1.5
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
10
102
0.98
0.00
1.4
1.4
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
11
111
0.99
0.00
1.2
1.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
167
1672
0.99
0.00
4.7
4.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
17
173
0.98
0.00
2.1
2.3
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
20
202
0.99
0.00
2.1
1.8
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3041672) Baker's yeast Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3029396) Erythrocyte agglutination [Presence] in Blood
0
9
0.00
0.00
0.0
3.7
—
—
—
0
0
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012320) Pathologist interpretation of Cerebral spinal fluid tests
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
8
79
1.01
0.00
1.3
1.5
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001964) Herpes simplex virus Ag [Presence] in Specimen
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3013247) Albumin in CSF/Albumin in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
5.6
—
0
6
(723473) SARS-CoV-2 (COVID-19) IgA Ab [Presence] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
59
0.84
0.00
2.2
2.2
—
—
—
0
0
(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3041365) Herpes simplex virus IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033888) Pepsinogen I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
56.2
—
0
5
(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood
0
5
0.00
0.00
0.0
6.6
—
—
—
0
0
(3027901) Hemoglobin [Mass/volume] in Arterial cord blood
0
6
0.00
0.00
0.0
1.0
—
173.8
—
0
6
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
8
79
1.01
0.00
1.0
1.1
—
10.3
—
0
16
(3003101) Alpha 1 antitrypsin [Mass/mass] in Stool
0
5
0.00
0.00
0.0
1.6
—
96.4
—
0
5
(3005593) Pancreatic islet cell Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
8
82
0.97
0.00
1.8
2.8
—
—
—
0
0
(3032352) Blasts [#/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
5.4
—
—
—
0
0
(3036048) Francisella tularensis Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3013784) Calcium.ionized [Moles/volume] in Serum or Plasma by Ion-selective membrane electrode (ISE)
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3042299) inFLIXimab [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
8.1
—
10.2
—
0
9
(3025378) Microscopic observation [Identifier] in Cervix by Cyto stain
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3014064) Pregnancy associated plasma protein A [Multiple of the median] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
17
170
1.00
0.00
1.1
1.5
—
—
—
0
0
(3005011) Chlamydia sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013803) Aspergillus fumigatus IgG Ab [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(21491868) Cryoglobulin [Mass/volume] in Serum
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3017115) Methotrexate [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
24.3
—
0.6
—
0
6
(3043410) Blood group antigens tested for on Red Blood Cells
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_ADREACT and mortality.

Females

Parameter HR [95% CI] p-value
E4_ADREACT 4.569 [3.1, 6.73] < 0.001
Birth year 0.992 [0.98, 1.0] 0.084

During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 2952 females with E4_ADREACT died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_ADREACT.

N-year risk Females Males
1 0.47% No data
5 2.272% No data
10 5.762% No data
15 11.548% No data
20 18.618% No data

Relationships between endpoints

Index endpoint: E4_ADREACT – Other adrenocortical overactivity

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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