Drug-induced acute pancreatitis

DRUGADVERS_ACUTE_PANCREATIT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K85.3#

1 out of 7 registries used, show all original rules.

57

4. Check minimum number of events

None

57

5. Include endpoints

None

57

6. Filter based on genotype QC (FinnGen only)

57

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 273 132 141
Only index persons 265 130 135
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.01
Median age at first event (years)
Whole population - 50.38 50.23
Only index persons 50.98 50.75 51.19

-FinnGen-

Key figures

All Female Male
Number of individuals 57 30 27
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 47.14 50.82 43.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
50
Matched controls
502
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K85.3
ICD-10 Finland
Drug-induced acute pancreatitis
+∞
71.5
50
*
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
125.1
16.8
17
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
26.7
14.5
20
12
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
15.3
11.3
19
19
L04AX01
ATC
azathioprine; systemic
17.4
10.3
16
13
A07EA06
ATC
budesonide; oral, local oral
20.9
9.7
14
9
JN3AD
NOMESCO Finland
Abdominal CT examination
20.9
9.7
14
9
K50.8
ICD-10 Finland
Other Crohn disease
61.1
9.0
10
*
A07EC02
ATC
mesalazine; oral, rectal
13.7
8.8
15
15
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.3
8.6
33
118
L01BB02
ATC
mercaptopurine; oral
53.7
8.0
9
*
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
93.4
7.6
8
*
K85.8
ICD-10 Finland
Other acute pancreatitis
93.4
7.6
8
*
H02AB06
ATC
prednisolone; systemic
5.2
7.2
33
135
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.7
6.6
21
56
K51.5
ICD-10 Finland
Left sided colitis
15.2
6.4
10
8
UJF32
NOMESCO Finland
Coloscopy
5.2
6.1
21
61

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3023368) Bacteria identified in Blood by Culture
39
80
13.27
21.98
6.8
4.5
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
20
19
15.68
19.35
2.1
1.5
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
48
168
12.71
15.23
13.4
4.0
g/l
34.2
36.6
1.66
48
159
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
23
45
7.89
12.51
6.5
2.3
u/l
93.7
28.6
2.54
23
36
(3022145) Colonoscopy Study observation
22
41
8.11
12.50
2.1
1.4
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
50
224
10.99
12.19
24.4
5.9
umol/l
14.0
11.1
0.55
50
213
(42870588) Differential panel, method unspecified - Blood
43
164
7.60
11.58
23.2
6.3
—
—
—
0
0
(3018418) pH of Serum or Plasma
35
111
6.58
11.52
8.3
3.8
ph
7.4
7.4
—
6
13
(3001604) Monocytes [#/volume] in Blood
50
240
9.79
10.95
25.1
6.7
e9/l
0.6
0.6
1.17
45
211
(3006315) Basophils [#/volume] in Blood
50
241
9.72
10.89
25.1
6.7
e9/l
0.0
0.0
0.58
45
211
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
40
156
6.24
10.09
10.7
3.3
u/l
49.6
27.8
0.97
40
144
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
43
181
6.60
9.86
19.4
6.2
mmol/l
1.2
1.2
0.75
36
159
(3019198) Lymphocytes [#/volume] in Blood
49
248
7.93
9.48
25.8
6.7
e9/l
2.1
2.0
0.28
43
221
(3013115) Eosinophils [#/volume] in Blood
49
248
7.93
9.48
28.7
6.8
e9/l
0.2
0.2
1.37
44
221
(3030467) Casts [#/volume] in Urine by Automated count
33
114
5.50
9.46
4.7
2.3
e6/l
0.2
0.3
0.55
27
86
(3026782) Osmolality of Urine
25
72
5.40
8.77
2.5
2.2
mosm/kgh2o
502.8
600.2
1.25
20
64
(3002582) Erythrocytes [#/volume] in Urine
33
121
5.10
8.63
4.5
2.3
e6/l
20.3
11.5
0.46
27
93
(3018095) Leukocytes [#/volume] in Urine
37
149
5.23
8.59
6.4
2.9
e6/l
47.6
38.4
0.12
28
102
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
13
20
8.13
8.47
1.2
1.3
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
20
49
5.75
8.36
1.5
1.7
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
30
104
4.98
8.36
16.3
3.7
%
97.5
94.5
0.25
30
104
(36304419) Bacteria [Presence] in Urine
31
112
4.88
8.16
4.6
2.3
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
34
136
4.72
7.77
6.6
6.2
inr
1.1
1.2
—
9
36
(3017181) Myelocytes/100 leukocytes in Blood
15
30
6.43
7.67
4.3
4.0
%
1.8
0.4
—
6
7
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
10
13
9.12
7.36
1.5
1.8
ug/l
4.3
19.4
—
10
13
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
33
137
4.35
7.00
4.8
2.6
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
50
305
6.19
6.71
6.4
3.8
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
24
82
4.33
6.56
1.7
1.7
—
—
—
0
0
(4035726)
14
31
5.66
6.39
1.5
1.3
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
21
66
4.45
6.38
4.6
2.3
e6/l
1.2
0.9
0.20
11
34
(3021440) Promyelocytes/100 leukocytes in Blood
13
29
5.51
5.85
4.5
4.1
%
0.2
0.0
—
5
7
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
27
110
3.76
5.63
1.7
1.7
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
16
47
4.34
5.20
6.7
1.8
nmol/l
349.2
381.5
0.27
16
42
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
38
201
3.67
5.19
5.7
3.2
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
39
210
3.71
5.18
31.2
8.3
e9/l
0.0
0.0
0.00
33
167
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
18
61
3.85
4.81
3.4
2.7
ng/l
243.8
1909.9
0.47
13
40
(3035350) Ketones [Presence] in Urine by Test strip
38
210
3.43
4.67
7.1
2.9
estimate
0.0
0.0
—
10
40
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
17
57
3.83
4.59
5.2
2.4
e6/l
2.9
2.9
—
7
25
(3044640) Blood type and Crossmatch panel - Blood
28
130
3.27
4.58
6.5
1.9
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
37
206
3.27
4.40
10.1
4.1
estimate
0.0
0.0
0.00
11
41
(3026008) Bacteria identified in Urine by Culture
22
90
3.35
4.39
5.3
2.5
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
37
207
3.24
4.35
7.3
2.9
estimate
0.0
0.0
0.00
11
40
(3000991) Gas panel - Venous blood
13
37
4.26
4.34
8.8
3.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
27
126
3.17
4.33
20.1
8.6
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
19
72
3.46
4.26
1.7
1.4
titre
240.0
483.1
—
6
13
(3015736) pH of Urine
33
176
3.08
4.16
5.1
2.6
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
14
45
3.80
3.97
1.7
1.6
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
10
25
4.64
3.88
4.0
4.0
g/l
65.5
66.8
—
10
25
(3014111) Lactate [Moles/volume] in Serum or Plasma
12
35
4.08
3.86
38.1
3.9
mmol/l
1.1
1.6
1.11
12
35
(3034770) Mitochondria Ab [Titer] in Serum
8
12
7.54
3.82
1.4
1.3
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
8
14
6.45
3.48
1.4
1.0
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
14
50
3.39
3.37
2.9
1.9
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
22
103
2.85
3.37
6.0
2.9
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
7
9.39
3.34
3.3
1.7
—
—
—
0
0
(3002256) Pathology report gross observation
13
45
3.45
3.28
1.2
1.1
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
6
8
8.21
3.13
1.3
1.0
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
6
8
8.21
3.13
1.3
1.0
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
21
100
2.74
3.08
6.1
1.9
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
12
42
3.35
2.96
2.4
2.0
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
25
134
2.54
2.87
1.6
1.4
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
12
43
3.27
2.85
37.4
2.1
kpa
5.5
5.7
0.21
12
43
(3025941) Bacteria identified in Stool by Culture
9
24
4.25
2.81
1.4
1.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
22
112
2.57
2.80
14.7
4.4
—
—
—
0
0
(3012544) pH of Venous blood
12
44
3.19
2.75
37.3
2.2
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
5
7
7.68
2.60
1.8
2.1
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
7
17
4.54
2.44
1.0
1.5
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
8
6.71
2.42
1.2
1.1
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
8
6.71
2.42
1.0
1.0
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
8
6.71
2.42
1.2
1.1
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
5
8
6.71
2.42
1.0
1.4
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
57
509
+∞
2.42
51.2
11.7
umol/l
75.3
73.4
0.18
57
509
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
57
508
+∞
2.41
41.8
9.3
u/l
39.0
27.6
1.32
57
494
(3002173) Hemoglobin [Mass/volume] in Arterial blood
9
29
3.49
2.34
9.0
7.3
g/l
128.8
124.3
—
9
29
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
7
18
4.28
2.33
15.0
3.7
%
105.7
93.3
—
7
18
(3023420) DNA double strand Ab [Units/volume] in Serum
5
9
5.96
2.26
1.0
1.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
7
19
4.05
2.23
2.3
6.1
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
24
139
2.26
2.22
4.9
2.9
ng/l
19.2
27.7
0.36
19
83
(3015171) Extractable nuclear Ab [Units/volume] in Serum
6
14
4.65
2.21
1.3
1.1
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
6
14
4.65
2.21
17.8
4.2
g/l
2.8
3.8
—
6
14
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
11
44
2.86
2.16
2.3
1.5
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
9
32
3.14
2.11
4.6
3.0
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
14
65
2.53
2.09
2.4
1.8
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
26
160
2.15
2.05
6.8
2.7
—
—
—
0
0
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
7
21
3.65
2.04
61.4
2.0
mmol/l
21.9
25.0
—
7
21
(3041096) Erythrocytes [Presence] in Urine by Automated
20
111
2.24
2.02
6.5
2.5
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
11
46
2.72
1.99
2.5
1.5
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
5
11
4.86
1.98
1.0
1.0
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
21
120
2.19
1.98
3.0
2.0
u/l
118.0
180.3
0.63
21
114
(40768797) Stomach Pathology biopsy report
12
53
2.60
1.97
1.2
1.2
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
7
22
3.48
1.95
11.3
8.3
%
93.4
94.6
—
7
22
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
6
17
3.81
1.89
16.8
4.0
%
161.2
165.6
—
6
17
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
5
12
4.45
1.86
1.0
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
19
107
2.16
1.84
7.8
2.9
estimate
0.0
0.0
—
9
41
(40761536) Microorganisms panel - Urine sediment
9
36
2.77
1.83
3.8
3.1
—
—
—
0
0
(40761535) Cells panel - Urine sediment
8
30
2.93
1.80
3.0
2.2
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
22
133
2.07
1.77
1.8
2.2
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
7
25
3.04
1.71
58.7
2.1
g/l
117.6
131.0
—
7
25
(3003327) Ova and parasites identified in Stool by Light microscopy
6
20
3.23
1.63
1.7
1.5
—
—
—
0
0
(3036489) Thrombin time
6
20
3.23
1.63
17.2
3.3
s
22.2
20.6
—
6
20
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
52
446
2.89
1.62
31.2
9.6
ml/min/173m2
92.8
91.0
0.22
47
350
(3008898) HLA-B27 [Presence]
8
33
2.65
1.61
1.0
1.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
26
172
1.94
1.60
2.5
1.8
—
—
—
0
0
(3019225) pH of Specimen
7
27
2.81
1.57
2.9
7.4
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
5
15
3.55
1.55
1.2
1.5
g/l
0.4
0.2
—
5
15
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
6
21
3.07
1.55
1.5
1.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
20
122
1.98
1.54
1.7
1.6
g/l
1.4
2.6
4.41
13
67
(3044889) 12 lead EKG panel
38
288
1.96
1.54
3.9
3.2
—
—
—
0
0
(40768443) Skin Pathology biopsy report
5
17
3.12
1.39
1.2
1.1
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
5
17
3.12
1.39
1.2
1.5
g/l
1.3
1.2
—
5
17
(3022313) Gas panel - Capillary blood
6
24
2.67
1.34
4.7
3.7
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
14
79
2.02
1.31
1.1
1.2
u/ml
1.2
3.1
—
7
34
(1761868) Lipid panel - Serum or Plasma
13
205
0.53
1.18
2.1
2.3
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
8
40
2.16
1.17
53.6
1.9
kpa
4.8
5.3
—
8
40
(3027273) Bicarbonate [Moles/volume] in Venous blood
5
21
2.51
1.11
3.6
2.2
mmol/l
25.3
24.0
—
5
21
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
5
22
2.39
1.05
81.6
1.9
%
0.7
0.8
—
5
22
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
6
29
2.19
0.92
80.8
3.7
mmol/l
24.0
24.7
—
6
29
(3000492) Spirometry study
8
43
2.00
0.92
2.0
1.4
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
21
153
1.59
0.83
3.5
1.8
pmol/l
85.5
95.1
0.82
16
80
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
13
84
1.71
0.80
1.5
1.3
iu/ml
7.9
30.3
—
6
27
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
5
23
2.28
0.78
81.6
1.9
%
1.8
1.6
—
5
23
(36660697) Celiac disease serology panel - Serum
8
51
1.66
0.64
1.5
1.2
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
10
67
1.60
0.54
2.8
2.3
%
1.5
1.5
—
10
61
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
0
16
0.00
0.42
0.0
1.4
—
—
—
0
0
(4010399)
5
34
1.51
0.41
1.4
1.4
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3013512) EKG study
13
99
1.41
0.40
5.1
3.5
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
10
75
1.40
0.33
1.5
1.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
12
95
1.33
0.29
1.8
2.4
—
—
—
0
0
(3039162) Centromere protein B Ab [Units/volume] in Serum
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(4094501)
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
11
130
0.81
0.18
1.5
1.6
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
41
390
1.18
0.16
3.2
3.5
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
9
83
1.10
0.07
1.7
2.2
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
9
83
1.10
0.07
1.0
1.6
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
9
86
1.06
0.07
1.6
1.3
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4027681)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
9
89
1.01
0.00
1.7
1.8
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
8
0.00
0.00
0.0
1.3
—
13.1
—
0
8
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
115.9
—
0
5
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
14.0
—
769.4
—
0
7
(4146454)
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
15.4
—
1184.0
—
0
7
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
5
49
1.02
0.00
1.6
2.2
—
—
—
0
0
(3011985) Renin [Units/volume] in Plasma
0
7
0.00
0.00
0.0
1.1
—
33.0
—
0
7
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
5
50
1.00
0.00
24.8
7.0
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005082) Progesterone [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
34.1
—
0
5
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
5
50
1.00
0.00
3.0
3.9
%
34.8
30.3
—
5
36
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint DRUGADVERS_ACUTE_PANCREATIT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have DRUGADVERS_ACUTE_PANCREATIT.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: DRUGADVERS_ACUTE_PANCREATIT – Drug-induced acute pancreatitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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