No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
137 |
4. Check minimum number of eventsNone |
137 |
5. Include endpointsNone |
137 |
6. Filter based on genotype QC (FinnGen only) |
137 |
Control definitions (FinnGen only)
- Control exclude
- D3_APLASTICANDOTHANAEMIA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D64
- Name in latin
- Aliae anaemia sideroblasticae
Similar endpoints
↥List of similar endpoints to
Other sideroblastic anaemias
based on the number of shared cases.
Similar with more cases:
- Other anaemias
- Aplastic and other anaemias
- Anaemias
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1579 | 915 | 635 |
| Only index persons | 1006 | 616 | 390 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.03 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 71.02 | 71.37 | 70.40 |
| Only index persons | 65.44 | 64.99 | 66.15 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 137 | 67 | 70 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | 66.35 | 63.51 | 69.07 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 126
- Matched controls
- 1258
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D64.3
ICD-10 Finland
Other sideroblastic anaemias
+∞
147.5
111
*
D64.9
ICD-10 Finland
Anaemia, unspecified
70.1
55.4
62
17
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
13.0
19.2
35
36
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.0
15.7
68
239
B82
ICPC
Anaemia other/unspecified
27.6
15.7
21
9
28500
ICD-8 Finland
Other and unspecified anaemias, Hypochromic anaemia with iron loading
+∞
11.6
11
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
19.4
11.6
17
10
ZX120
NOMESCO Finland
Intravenous
7.0
11.1
28
49
UJF92
NOMESCO Finland
Capsular endoscopy
26.0
10.5
14
6
WW500
NOMESCO Finland
Blood transfusion
11.0
10.2
19
20
XW000
NOMESCO Finland
Bone marrow biopsy
14.0
9.1
15
12
D50.8
ICD-10 Finland
Other iron deficiency anaemias
53.8
8.8
10
*
UJF32
NOMESCO Finland
Coloscopy
3.3
8.1
49
202
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.6
7.9
20
35
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
17.9
6.9
10
6
A02BC02
ATC
pantoprazole; systemic
2.8
6.7
92
613
D64.0
ICD-10 Finland
Hereditary sideroblastic anaemia
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
68
240
4.64
17.78
4.3
1.8
mg/l
4.0
3.0
2.07
60
201
(3001122) Ferritin [Mass/volume] in Serum or Plasma
78
390
3.32
10.89
8.0
2.4
ug/l
201.8
121.3
1.35
73
347
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
14
21
7.31
9.08
1.3
2.4
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
21
61
3.88
6.59
1.5
1.2
—
—
—
0
0
(3012544) pH of Venous blood
25
86
3.33
6.11
5.8
3.3
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
24
83
3.29
5.81
6.0
3.2
mmol/l
0.5
1.5
0.31
17
59
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
16
45
3.89
5.22
4.6
3.7
%
49.9
44.7
0.27
16
45
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
59
349
2.21
4.80
6.9
3.0
ng/l
2103.2
1443.8
0.64
53
287
(40758558) Short blood count panel - Blood
46
248
2.29
4.66
14.0
6.6
—
—
—
0
0
(3000991) Gas panel - Venous blood
19
67
3.13
4.43
13.2
7.5
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
34
164
2.43
4.41
3.0
3.0
e6/l
4.2
3.2
0.26
28
97
(42870588) Differential panel, method unspecified - Blood
53
315
2.11
4.15
10.2
4.6
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
27
120
2.56
4.14
8.4
5.4
mmol/l
2.3
1.3
0.32
22
93
(40768797) Stomach Pathology biopsy report
27
127
2.40
3.66
1.4
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
12
36
3.56
3.57
2.0
2.6
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
73
510
1.92
3.48
11.4
5.6
mmol/l
1.2
1.2
0.52
64
426
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
25
117
2.39
3.42
2.4
1.7
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
69
475
1.91
3.42
10.1
5.2
e9/l
0.6
0.6
0.02
62
407
(3013115) Eosinophils [#/volume] in Blood
71
495
1.90
3.37
11.3
5.3
e9/l
0.2
0.2
0.43
66
436
(3006315) Basophils [#/volume] in Blood
69
477
1.90
3.36
10.1
5.3
e9/l
0.0
0.0
0.11
62
411
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
25
119
2.35
3.30
2.4
1.8
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
32
170
2.15
3.26
2.6
1.8
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
64
439
1.86
3.14
2.4
1.9
pmol/l
92.4
100.4
0.72
36
209
(3004588) Protein electrophoresis panel - Serum or Plasma
17
69
2.67
3.10
1.2
2.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
32
174
2.09
3.06
2.7
2.8
e6/l
0.7
1.3
0.96
26
105
(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture
5
5
10.31
3.00
4.8
1.8
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
65
456
1.81
2.91
11.5
5.3
%
60.9
58.4
0.74
60
417
(3007853) Bacteria identified in Skin by Aerobe culture
23
114
2.22
2.76
1.7
1.6
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
18
80
2.44
2.75
1.5
1.5
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
9
24
3.94
2.72
6.3
1.8
g/l
3.2
3.7
—
9
24
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
9
25
3.78
2.62
1.3
1.5
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
6
11
5.65
2.57
1.5
1.2
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
61
432
1.74
2.56
15.8
9.7
e9/l
0.0
0.0
0.21
52
349
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
14
57
2.62
2.54
2.3
1.6
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
51
344
1.77
2.53
3.5
3.3
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
7
16
4.55
2.51
2.4
2.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
55
382
1.73
2.45
4.1
3.1
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
64
470
1.68
2.29
11.8
4.9
mmol/l
1.2
1.2
0.36
58
418
(3042111) Morphology [Interpretation] in Bone marrow Narrative
7
18
4.04
2.28
1.7
1.4
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
13
54
2.55
2.27
2.5
2.4
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
10
36
2.92
2.25
3.7
2.1
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
44
293
1.74
2.25
7.2
4.0
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
5
9
5.72
2.23
3.6
2.7
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
58
418
1.67
2.21
5.9
4.0
ng/l
33.1
57.5
1.03
45
295
(40760888) Immunoglobulin light chains.free panel - Serum
7
19
3.82
2.18
2.1
4.2
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
26
148
1.93
2.18
2.7
1.9
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
6
14
4.43
2.17
1.2
1.1
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
56
402
1.66
2.16
2.7
2.1
nmol/l
76.6
78.3
0.22
51
340
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
11
43
2.69
2.15
1.1
1.5
—
—
—
0
0
(3018418) pH of Serum or Plasma
46
314
1.70
2.14
8.3
3.8
ph
7.4
7.4
—
9
56
(3014051) Protein [Presence] in Urine by Test strip
8
25
3.33
2.13
4.4
2.4
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
9
32
2.94
2.04
1.2
1.2
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
72
559
1.61
1.99
20.2
9.1
e9/l
3.9
4.1
0.46
66
486
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
5
11
4.67
1.96
1.2
1.9
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
5
11
4.67
1.96
1.2
1.9
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
11
4.67
1.96
1.4
1.3
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
16
3.87
1.95
2.0
2.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
47
330
1.65
1.94
4.1
3.1
e6/l
26.9
75.4
0.88
41
257
(21494755) Public health laboratory ask at order entry panel
0
51
0.00
1.93
0.0
1.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
42
288
1.66
1.90
3.8
2.9
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
5
12
4.28
1.84
2.4
1.7
pg
33.8
31.5
—
5
12
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
5
12
4.28
1.84
1.0
1.8
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
18
306
0.53
1.77
3.0
3.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
36
241
1.67
1.77
13.8
2.2
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
5
13
3.95
1.73
1.0
1.7
nmol/l
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
94
793
1.59
1.72
14.6
6.7
u/l
85.1
77.3
1.06
87
724
(3028026) IgM [Mass/volume] in Serum or Plasma
11
49
2.35
1.68
1.4
1.8
g/l
2.2
1.9
0.09
11
43
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
6
19
3.25
1.68
2.3
1.8
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
13
63
2.17
1.66
5.5
4.0
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
14
3.66
1.63
2.2
2.1
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
12
57
2.21
1.60
4.5
2.9
g/l
122.3
126.1
0.24
12
57
(3007164) IgA [Mass/volume] in Serum or Plasma
26
164
1.72
1.58
1.3
1.3
g/l
3.3
2.4
0.41
19
96
(40768806) Pleura Pathology biopsy report
5
15
3.42
1.53
1.6
2.4
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
7
28
2.58
1.47
2.0
3.1
mmol/l
1.3
1.5
—
7
28
(3044640) Blood type and Crossmatch panel - Blood
45
332
1.53
1.46
10.2
2.2
—
—
—
0
0
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
9
39
2.40
1.46
1.1
1.5
g/l
15.4
10.1
—
9
34
(3013707) Erythrocyte sedimentation rate by Westergren method
86
727
1.49
1.43
5.5
4.1
mm/h
20.8
13.3
2.02
78
650
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
5
17
3.01
1.37
2.6
1.6
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
14
76
1.94
1.35
3.2
3.5
ml/min/173m2
59.0
61.2
—
6
30
(3005719) IgG [Mass/volume] in Serum or Plasma
12
62
2.03
1.32
4.1
1.9
g/l
16.1
9.7
1.01
12
53
(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis
8
34
2.43
1.31
1.1
1.5
g/l
34.5
35.9
—
8
29
(3027273) Bicarbonate [Moles/volume] in Venous blood
10
48
2.17
1.31
5.3
3.1
mmol/l
23.9
24.6
—
10
48
(3013826) Glucose [Moles/volume] in Serum or Plasma
73
606
1.44
1.28
8.5
4.1
mmol/l
7.3
6.7
1.29
68
564
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
12
63
1.99
1.27
2.3
3.1
mmol/l
2.9
2.3
—
5
47
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
13
71
1.92
1.24
2.8
2.9
kpa
5.4
5.1
0.36
13
62
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
6
26
2.37
1.20
8.8
1.5
%
86.0
90.2
—
6
26
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
26
2.37
1.20
2.3
1.7
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
5
20
2.55
1.16
1.2
1.3
g/l
0.2
0.2
—
5
20
(3034860) Kappa light chains.free [Mass/volume] in Serum
7
31
2.32
1.12
2.1
3.1
mg/l
115.2
265.7
—
7
23
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
7
31
2.32
1.12
2.1
3.1
mg/l
89.9
30.7
—
7
23
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
5
21
2.43
1.10
1.2
1.3
g/l
0.9
1.1
—
5
21
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
9
46
2.02
1.06
5.6
2.3
%
0.8
0.7
—
9
46
(3048929) Epstein Barr virus Ab [Presence] in Serum
5
22
2.32
1.04
1.8
1.1
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
9
48
1.94
1.03
5.6
2.3
%
1.6
1.3
—
9
48
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
27
2.28
0.94
2.3
1.7
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
6
28
2.19
0.92
2.0
3.1
mmol/l
7.2
7.6
—
6
28
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
26
188
1.47
0.92
1.1
1.2
u/ml
0.8
0.8
—
5
53
(40760892) CBC W Ordered Manual Differential panel - Blood
27
197
1.46
0.91
9.0
5.7
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
6
29
2.12
0.90
2.2
2.4
kpa
8.3
7.9
—
6
24
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
8
136
0.56
0.89
1.6
1.4
—
—
—
0
0
(3022313) Gas panel - Capillary blood
8
44
1.87
0.87
2.1
3.1
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
33
253
1.40
0.86
8.7
3.4
%
73.3
86.7
2.32
33
247
(4034850)
6
31
1.98
0.85
24.7
16.3
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
18
122
1.55
0.85
19.7
9.2
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
52
431
1.33
0.84
15.1
9.0
inr
1.2
1.3
0.23
15
115
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
32
246
1.39
0.82
1.7
1.8
pmol/l
546.2
452.6
0.63
26
202
(3037467) Urinalysis macro (dipstick) panel - Urine
79
697
1.32
0.81
5.2
4.4
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
13
82
1.65
0.81
1.7
1.4
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
29
220
1.40
0.80
4.7
4.9
kg/l
1.0
1.0
—
7
33
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
8
48
1.71
0.80
14.3
6.1
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
77
678
1.31
0.80
6.1
4.7
—
4312.6
—
0
13
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
30
230
1.39
0.78
9.6
1.6
mg/l
1.3
1.5
0.26
24
176
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
13
83
1.63
0.78
1.8
3.7
mmol/l
1.2
1.2
0.38
13
73
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
15
101
1.54
0.74
1.7
1.5
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
5
25
2.04
0.73
1.0
1.1
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
27
206
1.39
0.73
6.7
3.3
ng/l
631.3
125.9
0.84
27
160
(3015377) Calcium [Moles/volume] in Serum or Plasma
43
354
1.31
0.72
4.3
3.0
mmol/l
2.4
2.3
0.05
38
300
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
106
983
1.35
0.71
33.8
14.6
mg/l
26.5
25.1
0.18
91
791
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
56
480
1.28
0.69
14.9
4.0
—
—
—
0
0
(3022621) pH of Urine by Test strip
12
78
1.59
0.68
3.7
3.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
10
62
1.66
0.67
1.5
1.7
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
22
0.00
0.60
0.0
2.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
47
401
1.26
0.59
2.2
2.2
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
23
0.00
0.59
0.0
1.4
—
39.5
—
0
23
(4094501)
0
23
0.00
0.59
0.0
1.2
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
6
39
1.56
0.53
1.7
3.2
%
1.6
1.6
—
6
34
(3000492) Spirometry study
12
84
1.47
0.51
1.5
1.4
—
—
—
0
0
(3013512) EKG study
38
324
1.24
0.47
4.9
4.2
—
—
—
0
0
(40761535) Cells panel - Urine sediment
12
86
1.43
0.46
5.7
3.8
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
8
57
1.43
0.43
1.4
1.3
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
16
125
1.32
0.39
1.6
1.7
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
32
369
0.83
0.37
4.4
5.2
ug/l
2.8
3.0
0.06
27
320
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
25
294
0.82
0.35
3.6
4.5
%
14.8
21.1
—
9
149
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
6
43
1.41
0.35
2.0
2.0
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
52
1.36
0.32
1.1
1.3
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
8
106
0.74
0.30
4.4
3.7
—
—
—
0
0
(3019225) pH of Specimen
13
103
1.29
0.29
4.8
3.1
—
—
—
0
0
(4010399)
5
73
0.67
0.27
1.2
1.3
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
91
949
0.88
0.26
4.4
4.6
mmol/l
4.0
4.5
4.49
83
862
(3009508) Creatinine [Moles/volume] in Urine
34
305
1.15
0.25
3.5
3.0
mmol/l
7.4
7.1
0.16
28
244
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
6
85
0.69
0.24
1.8
1.8
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
5
38
1.33
0.23
1.2
1.1
—
—
—
0
0
(3020891) Body temperature
5
38
1.33
0.23
11.4
4.2
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
93
966
0.88
0.23
4.7
5.2
mmol/l
2.3
2.6
3.95
85
874
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
55
513
1.12
0.22
2.6
2.9
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3008401) Mugwort IgE Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.0
—
1.6
—
0
5
(3051611) Lipemic interference index of Serum or Plasma
0
10
0.00
0.21
0.0
3.5
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3003888) Timothy IgE Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.0
—
4.8
—
0
5
(3003740) Influenza virus B Ag [Presence] in Specimen
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3044889) 12 lead EKG panel
74
704
1.11
0.21
4.6
4.1
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
91
943
0.90
0.20
4.4
4.6
mmol/l
1.4
1.5
0.96
81
854
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
6
52
1.16
0.19
4.2
3.6
pmol/l
3.4
4.4
—
6
45
(3029937) Albumin [Presence] in Urine by Test strip
30
272
1.13
0.19
4.0
4.5
estimate
0.0
0.0
—
9
80
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
7
59
1.20
0.18
1.4
1.7
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
94
909
1.11
0.18
7.0
6.2
mmol/mol
41.4
40.4
0.35
84
833
(3008152) Bicarbonate [Moles/volume] in Arterial blood
5
68
0.73
0.17
6.4
5.6
mmol/l
24.9
24.4
—
5
62
(40761511) CBC panel - Blood by Automated count
104
1013
1.11
0.16
33.9
13.7
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
8
72
1.12
0.16
1.4
1.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
14
121
1.17
0.15
1.2
1.4
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
51
484
1.09
0.14
6.7
5.7
estimate
0.0
0.0
—
10
84
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
93
954
0.92
0.13
5.5
4.9
mmol/l
6.3
6.0
1.08
84
861
(3002256) Pathology report gross observation
14
123
1.15
0.13
1.3
1.3
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
93
908
1.08
0.11
28.5
14.3
ml/min/173m2
73.4
75.9
0.41
84
732
(3020682) Albumin/Creatinine [Ratio] in Urine
34
320
1.08
0.11
3.7
3.9
mg/mmol
8.6
12.6
0.30
22
192
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
89
911
0.93
0.10
4.0
4.1
mmol/l
1.2
1.3
0.55
79
818
(3009542) Hematocrit [Volume Fraction] of Blood
86
839
1.07
0.10
43.4
15.7
%
34.9
38.8
2.40
59
565
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
7
67
1.05
0.08
2.0
1.8
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
50
483
1.06
0.07
5.1
4.3
estimate
0.0
0.0
—
9
86
(40761536) Microorganisms panel - Urine sediment
7
82
0.85
0.07
4.1
4.1
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
20
213
0.93
0.06
3.2
3.0
ug/l
0.6
0.8
0.89
13
150
(4035726)
10
90
1.12
0.05
1.5
1.5
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
26
272
0.95
0.05
5.5
3.8
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
50
488
1.04
0.04
5.3
4.3
estimate
0.0
0.0
—
7
81
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
73
721
1.03
0.02
3.8
3.8
pmol/l
14.6
15.0
0.51
67
644
(3003694) ABO and Rh group [Type] in Blood
26
268
0.96
0.02
1.6
1.3
—
—
—
0
0
(3024731) MCV [Entitic volume]
108
1072
1.04
0.02
54.2
21.6
fl
90.3
91.4
0.88
108
1048
(3035941) MCH [Entitic mass]
108
1073
1.03
0.01
54.1
21.5
pg
29.4
30.4
3.27
108
1049
(3000963) Hemoglobin [Mass/volume] in Blood
108
1073
1.03
0.01
54.7
21.8
g/l
119.0
134.1
13.84
108
1047
(3012516) Albumin [Mass/volume] in Urine
29
296
0.97
0.00
3.3
3.1
mg/l
54.7
527.4
0.87
21
183
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
11
113
0.97
0.00
1.1
1.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
89
887
1.01
0.00
4.4
4.7
mu/l
1.9
2.0
0.42
81
789
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
39
385
1.02
0.00
5.2
4.5
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
23
228
1.01
0.00
4.8
4.4
—
—
—
0
0
(3022145) Colonoscopy Study observation
11
105
1.05
0.00
1.4
1.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
64
0.93
0.00
1.0
1.2
—
—
—
0
0
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
6
0.00
0.00
0.0
1.0
—
11.0
—
0
6
(3037556) Urate [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3026470) Cobalt [Mass/volume] in Blood
0
7
0.00
0.00
0.0
2.0
—
2.9
—
0
7
(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
1.4
—
0
5
(3029075) Extractable nuclear Ab panel - Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(3006245) CD3-CD19+ cells/100 cells in Blood
0
6
0.00
0.00
0.0
3.0
—
3.0
—
0
6
(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood
0
5
0.00
0.00
0.0
2.8
—
28.4
—
0
5
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019060) Gas panel - Arterial blood
7
74
0.94
0.00
2.7
3.2
—
—
—
0
0
(44806420)
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
5
0.00
0.00
0.0
1.6
—
18.3
—
0
5
(3023511) Choriogonadotropin [Units/volume] in Urine
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016244) Insulin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
11.8
—
0
5
(3027231) Wheat IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
8
0.00
0.00
0.0
3.6
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027831) CD3-CD16+CD56+ (Natural killer) cells/100 cells in Blood
0
5
0.00
0.00
0.0
2.6
—
10.6
—
0
5
(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
278.5
—
0
6
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
1.7
—
0
5
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
2.0
—
5.3
—
0
8
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
85.7
—
0
6
(3004451) EKG impression Narrative
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
63.8
—
0
5
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_SIDEROANAMIEAOTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SIDEROANAMIEAOTHER | 2.545 [1.95, 3.32] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 302 out of 565 females with D3_SIDEROANAMIEAOTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SIDEROANAMIEAOTHER | 2.558 [1.77, 3.69] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.096 |
During the follow-up period (1.1.1998 — 31.12.2019), 213 out of 380 males with D3_SIDEROANAMIEAOTHER died.
Mortality risk
Mortality risk for people of age
years, who have D3_SIDEROANAMIEAOTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.199% | 0.607% |
| 5 | 1.237% | 3.073% |
| 10 | 2.959% | 8.425% |
| 15 | 5.515% | 15.674% |
| 20 | 9.1% | 26.053% |
Relationships between endpoints
↥Index endpoint: D3_SIDEROANAMIEAOTHER – Other sideroblastic anaemias
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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