This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Immunodeficiency following hereditary defective response to Epstein-Barr virus
D3_IMMUDEFPOSTEBV
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
6 |
4. Check minimum number of eventsNone |
6 |
5. Include endpointsNone |
6 |
6. Filter based on genotype QC (FinnGen only) |
6 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D82
- Name in latin
- Deficientia immunalis cum responso defectivo contra agentem viralem Epstein-Barr
Similar endpoints
↥List of similar endpoints to
Immunodeficiency following hereditary defective response to Epstein-Barr virus
based on the number of shared cases.
Similar with more cases:
- Immunodeficiency associated with other major defects
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
Not enough data for upset plot.
Not enough data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 41 | 20 | 21 |
| Only index persons | 33 | 16 | 17 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | - | 59.10 | 42.81 |
| Only index persons | 51.71 | 54.86 | 48.74 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6 | - | - |
| Unadjusted period prevalence (%) | 0.00 | - | - |
| Median age at first event (years) | 50.49 | - | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3037467) Urinalysis macro (dipstick) panel - Urine
6
33
+∞
1.13
8.5
3.7
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
0
16
0.00
0.49
0.0
2.3
—
0.7
—
0
10
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
6
49
+∞
0.24
22.8
9.3
mg/l
21.7
14.7
—
6
42
(3017446) Testosterone [Moles/volume] in Serum or Plasma
0
9
0.00
0.23
0.0
1.8
—
13.8
—
0
9
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
6
0.00
0.00
0.0
3.7
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
39.4
—
0
5
(3020564) Creatinine [Moles/volume] in Serum or Plasma
6
55
+∞
0.00
26.2
12.1
umol/l
68.7
78.6
—
6
55
(40760892) CBC W Ordered Manual Differential panel - Blood
0
8
0.00
0.00
0.0
10.9
—
—
—
0
0
(3000492) Spirometry study
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000991) Gas panel - Venous blood
0
5
0.00
0.00
0.0
4.2
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
0
5
0.00
0.00
0.0
3.2
—
0.1
—
0
5
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(1002224) Polysomnography panel
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_IMMUDEFPOSTEBV and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have D3_IMMUDEFPOSTEBV.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: D3_IMMUDEFPOSTEBV – Immunodeficiency following hereditary defective response to Epstein-Barr virus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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