hypersplenism: Overactive functioning of the spleen, resulting in excessive destruction of blood cells.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
146 |
4. Check minimum number of eventsNone |
146 |
5. Include endpointsNone |
146 |
6. Filter based on genotype QC (FinnGen only) |
146 |
Control definitions (FinnGen only)
- Control exclude
- D3_BLOODOTHER
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D73
- Name in latin
- Hypersplenismus
Similar endpoints
↥List of similar endpoints to
Hypersplenism
based on the number of shared cases.
Similar with more cases:
- Diseases of spleen
- Other diseases of blood and blood-forming organs, wide
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1082 | 469 | 602 |
| Only index persons | 882 | 381 | 501 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.02 |
| Only index persons | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 58.66 | 59.57 | 57.67 |
| Only index persons | 56.73 | 57.62 | 56.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 146 | 63 | 83 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.04 |
| Median age at first event (years) | 57.70 | 56.06 | 58.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 132
- Matched controls
- 1320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D73.1
ICD-10 Finland
Hypersplenism
4503599627370496.0
179.9
129
*
XW000
NOMESCO Finland
Bone marrow biopsy
47.8
39.1
47
15
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
54.2
28.4
33
8
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
160.2
25.6
26
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
9.2
22.0
51
84
D64.9
ICD-10 Finland
Anaemia, unspecified
10.3
20.1
42
57
JMA10
NOMESCO Finland
Transabdominal total splenectomy
+∞
17.0
16
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
9.3
16.2
35
49
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.3
15.4
36
57
JN4BD
NOMESCO Finland
Extensive body CT
8.0
15.1
36
59
D70.89
ICD-10 Finland
Neutropenic splenomegaly
+∞
14.9
14
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
32.1
13.3
17
6
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
16.4
13.3
21
15
C03DA01
ATC
spironolactone; oral
7.9
13.2
31
49
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
55.9
13.1
15
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.2
13.1
67
260
WW500
NOMESCO Finland
Blood transfusion
11.7
11.5
21
21
C03CA01
ATC
furosemide; systemic
3.9
11.1
57
215
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
10.5
78
390
R50.9
ICD-10 Finland
Fever, unspecified
4.7
10.4
38
104
M04AA01
ATC
allopurinol; systemic
5.1
9.9
33
81
TPH04
NOMESCO Finland
Cathetrisation of vein
4.0
9.9
46
157
ZX120
NOMESCO Finland
Intravenous
5.9
9.9
28
57
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
26.1
9.1
12
5
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
95.9
8.5
9
*
J01MA12
ATC
levofloxacin; systemic
3.5
8.5
45
169
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
+∞
8.4
8
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
8.4
8
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.7
8.4
29
74
A46
ICD-10 Finland
Erysipelas
4.2
8.3
33
97
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
35.7
8.2
10
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
7.0
7.6
18
29
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
84.6
7.5
8
*
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
7.4
7
*
WW200
NOMESCO Finland
Immunization
9.6
7.3
14
16
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
9.6
7.3
14
16
A05AA02
ATC
ursodeoxycholic acid; oral
21.4
7.2
10
5
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
31.9
7.2
9
*
L01XX05
ATC
hydroxycarbamide; oral
31.9
7.2
9
*
JN4AD
NOMESCO Finland
Body CT examination
5.2
7.2
22
49
J01MA02
ATC
ciprofloxacin; systemic
2.7
7.0
65
346
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.7
6.8
19
38
TPH07
NOMESCO Finland
Cathetrisation of artery
4.3
6.5
24
65
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.1
6.5
40
164
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
6.4
31
107
K76.6
ICD-10 Finland
Portal hypertension
+∞
6.3
6
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
6.3
6
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
+∞
6.3
6
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.3
6.3
13
17
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.9
6.1
16
30
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3045142) Bone marrow Pathology biopsy report
37
10
49.22
61.13
1.7
1.2
—
—
—
0
0
(3027945) Reticulocytes/100 erythrocytes in Blood
73
126
10.59
45.87
4.6
2.2
%
2.1
1.7
2.16
67
112
(3042111) Morphology [Interpretation] in Bone marrow Narrative
31
15
25.97
41.97
2.2
1.5
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
61
96
10.20
40.87
5.2
2.1
e9/l
82.2
67.2
1.55
50
75
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
57
88
9.99
38.60
4.4
2.4
g/l
0.2
0.2
1.77
52
81
(3023183) Ammonium ion [Moles/volume] in Plasma
34
25
17.43
37.81
6.6
2.0
umol/l
47.7
34.4
1.09
29
20
(3004588) Protein electrophoresis panel - Serum or Plasma
50
67
10.83
37.80
1.9
1.6
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
49
64
11.02
37.76
3.1
1.9
g/l
1.2
1.8
0.56
42
59
(42870588) Differential panel, method unspecified - Blood
109
359
9.03
35.67
16.2
5.4
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
32
26
15.48
33.52
1.8
2.0
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
31
27
14.31
31.08
1.3
1.1
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
119
512
8.16
26.77
18.1
5.7
%
0.8
0.7
0.48
114
482
(3006504) Eosinophils/100 leukocytes in Blood
120
524
8.24
26.44
18.0
5.7
%
2.9
2.7
0.26
115
496
(3019069) Monocytes/100 leukocytes in Blood
120
530
8.10
25.91
19.1
6.0
%
9.0
8.6
0.75
115
505
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
28
28
12.14
25.54
4.0
2.1
g/l
2.3
4.3
4.92
28
28
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
59
142
6.29
25.31
3.8
2.3
%
23.0
24.8
0.30
49
123
(40760888) Immunoglobulin light chains.free panel - Serum
24
19
14.92
25.22
2.1
4.9
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
120
544
7.77
24.71
18.9
5.8
%
26.4
27.3
0.33
115
514
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
35
50
8.89
24.51
2.5
1.8
g/l
0.8
1.5
4.02
25
41
(3013115) Eosinophils [#/volume] in Blood
123
583
8.04
23.70
17.1
5.7
e9/l
0.2
0.2
0.35
108
518
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
31
42
9.10
22.57
1.6
1.3
—
—
—
0
0
(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
31
42
9.10
22.57
1.6
1.3
g/l
5.9
7.5
3.14
20
33
(3018010) Neutrophils/100 leukocytes in Blood
116
537
6.65
22.47
17.2
5.6
%
58.4
57.9
0.15
110
512
(3001604) Monocytes [#/volume] in Blood
119
569
6.90
22.01
16.1
5.5
e9/l
0.6
0.6
0.12
108
494
(3019198) Lymphocytes [#/volume] in Blood
120
581
6.98
21.78
16.3
5.6
e9/l
1.5
1.8
2.11
112
518
(3006315) Basophils [#/volume] in Blood
118
569
6.60
21.34
16.3
5.5
e9/l
0.0
0.0
0.20
106
498
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
30
42
8.73
21.22
1.6
1.3
g/l
3.4
3.9
1.00
18
31
(3017143) Hepatitis C virus Ab [Presence] in Serum
55
145
5.48
20.88
1.7
1.5
—
—
—
0
0
(4035726)
45
100
6.06
20.62
1.8
1.3
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
56
153
5.32
20.33
1.8
1.4
titre
448.0
506.3
—
10
32
(3023368) Bacteria identified in Blood by Culture
82
305
4.85
20.27
10.3
4.7
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
21
19
12.74
20.23
1.5
1.3
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
21
19
12.74
20.23
1.1
1.3
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
59
170
5.15
20.08
1.9
1.6
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
71
241
4.79
19.63
3.1
1.9
mg/l
3.5
2.9
1.04
60
210
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
20
18
12.72
19.30
1.5
1.3
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
126
674
7.35
19.29
22.3
8.8
e9/l
4.4
4.2
0.09
117
581
(21494434) Karyotype in Bone marrow
24
8
35.49
19.03
1.3
1.0
—
—
—
0
0
(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
27
38
8.49
18.92
1.7
1.3
g/l
2.8
2.9
0.08
18
32
(3002179) Metamyelocytes/100 leukocytes in Blood
39
82
6.13
18.82
9.5
5.6
%
1.3
0.2
1.47
18
22
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
50
135
5.11
18.20
9.1
2.8
umol/l
10.9
4.9
2.29
44
116
(3017181) Myelocytes/100 leukocytes in Blood
40
89
5.81
18.13
10.9
5.5
%
1.9
1.0
0.71
23
30
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
18
16
12.69
17.43
1.2
1.3
u/ml
278.5
195.4
—
8
9
(3000093) Morphology [Interpretation] in Blood Narrative
21
6
40.47
17.20
1.1
1.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
94
428
4.36
16.85
17.6
8.9
inr
1.4
1.2
0.75
28
121
(3021440) Promyelocytes/100 leukocytes in Blood
37
82
5.70
16.76
10.6
5.8
%
0.2
0.2
0.03
23
29
(3021879) Hepatitis B virus core Ab [Presence] in Serum
41
100
5.31
16.69
1.6
1.5
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
18
18
11.27
16.14
1.2
1.2
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
15
12
13.82
15.38
1.1
1.0
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
15
12
13.82
15.38
1.1
1.2
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
21
29
8.29
14.81
1.2
1.3
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
54
180
4.17
14.65
2.1
1.7
nmol/l
1242.2
1231.1
0.03
44
148
(3025159) Blasts/100 leukocytes in Blood
34
79
5.31
14.50
10.4
6.0
%
0.4
0.3
0.04
21
24
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
102
533
4.03
14.11
13.7
6.9
mmol/l
1.2
1.2
1.47
88
461
(46235355) HIV 1 and 2 tests - Meaningful Use set
60
221
3.91
14.06
1.9
1.7
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
52
174
4.09
13.96
3.5
1.9
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
61
229
3.86
13.88
2.7
1.4
g/l
2.4
2.6
0.23
45
139
(3016650) Hepatitis A virus Ab [Presence] in Serum
16
17
10.45
13.69
1.1
1.1
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
17
6
31.75
13.29
3.6
2.2
u/ml
1508.5
793.7
—
17
6
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
31
72
5.20
13.16
3.4
1.6
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
78
355
3.57
13.06
7.6
2.3
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
14
14
10.95
12.43
5.9
3.7
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
50
179
3.73
11.97
3.7
2.5
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
70
311
3.40
11.95
5.0
2.4
umol/l
347.2
4980.1
1.30
64
270
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
19
30
7.13
11.87
3.4
1.8
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
19
30
7.13
11.87
2.0
1.1
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
16
8
22.22
11.41
2.4
2.1
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
38
117
4.04
11.23
2.5
1.8
—
—
—
0
0
(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood
12
11
11.80
11.20
4.2
1.6
e6/l
264.0
644.0
—
6
6
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
38
121
3.89
10.67
2.6
1.8
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
74
360
3.14
10.55
5.3
2.8
u/l
56.6
54.3
0.11
68
337
(3000991) Gas panel - Venous blood
33
98
4.06
10.18
8.8
7.1
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
16
25
7.06
10.03
3.1
1.6
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
19
36
5.92
9.93
2.3
3.2
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
17
29
6.50
9.84
3.9
1.8
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
18
33
6.08
9.72
2.2
1.3
g/l
1.1
1.1
0.17
18
33
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
11
11
10.73
9.66
3.6
1.4
pg
34.0
34.2
0.05
11
11
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
14
20
7.64
9.46
3.7
1.7
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
14
9
17.03
9.24
2.4
2.4
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
13
7
20.19
9.11
1.2
1.4
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
58
266
2.96
8.88
6.2
2.2
—
—
—
0
0
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
22
54
4.62
8.61
7.0
3.9
mmol/l
23.9
24.6
0.42
22
46
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
92
545
2.86
8.60
10.6
4.2
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
13
19
7.41
8.59
6.0
3.8
%
60.4
60.3
0.00
13
19
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
13
19
7.41
8.59
1.7
1.5
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
38
139
3.34
8.53
1.6
1.3
—
—
—
0
0
(3018418) pH of Serum or Plasma
66
332
2.80
8.42
8.2
3.6
ph
7.4
7.4
0.54
15
58
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
12
17
7.60
8.12
1.8
1.4
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
11
14
8.42
8.10
1.2
1.3
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
15
28
5.86
7.91
4.5
2.0
%
180.5
200.1
0.25
15
28
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
17
36
5.21
7.86
2.6
3.2
—
—
—
0
0
(3012544) pH of Venous blood
33
116
3.38
7.85
6.6
3.8
—
—
—
0
0
(3022313) Gas panel - Capillary blood
20
49
4.57
7.83
5.4
3.6
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
76
423
2.66
7.80
2.8
1.8
pmol/l
100.7
95.3
0.31
44
215
(3002032) Base excess in Venous blood by calculation
32
111
3.41
7.77
6.2
3.5
mmol/l
1.9
1.9
0.01
27
85
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
12
9
14.38
7.53
1.1
1.0
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
14
26
5.85
7.41
2.0
1.7
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
12
19
6.79
7.36
5.1
2.9
e9/l
4.2
4.8
0.18
12
19
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
15
30
5.46
7.36
1.1
1.1
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
35
134
3.12
7.21
1.9
1.7
—
—
—
0
0
(3026782) Osmolality of Urine
48
220
2.76
7.14
4.3
3.1
mosm/kgh2o
511.0
555.4
0.82
48
189
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
16
35
5.01
7.12
1.4
1.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
66
359
2.53
6.90
4.8
3.1
e6/l
48.0
196.9
0.39
54
276
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
23
69
3.77
6.89
6.1
3.5
mmol/l
1.3
1.5
0.09
14
50
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
73
417
2.50
6.86
5.1
3.0
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
10
6
17.74
6.85
1.1
1.0
—
—
—
0
0
(4062490)
10
14
7.59
6.78
1.4
1.3
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
71
403
2.48
6.74
5.4
3.5
e6/l
42.0
60.3
0.28
57
294
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
13
25
5.61
6.62
1.2
1.3
—
—
—
0
0
(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma
10
7
15.20
6.49
1.4
1.1
mg/l
3.1
4.9
—
10
7
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
50
245
2.58
6.43
3.0
1.6
mg/l
1.6
1.0
0.65
40
191
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
10
8
13.30
6.18
1.7
1.3
—
—
—
0
0
(3019225) pH of Specimen
26
91
3.26
6.16
9.5
4.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
52
267
2.47
6.01
12.0
4.7
—
—
—
0
0
(40758558) Short blood count panel - Blood
54
284
2.43
5.91
14.2
6.8
—
—
—
0
0
(4281824)
10
9
11.81
5.89
1.1
1.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
14
33
4.59
5.70
5.7
2.3
u/ml
0.4
0.3
—
8
19
(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma
9
7
13.59
5.66
2.2
2.0
u/l
24.0
10.9
—
9
7
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
11
21
5.58
5.62
2.2
1.8
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
11
21
5.58
5.62
2.2
1.8
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
58
321
2.34
5.61
4.8
2.8
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
59
333
2.30
5.42
4.8
2.9
e6/l
0.2
0.4
0.89
47
247
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
12
26
4.94
5.36
1.7
1.5
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
12
26
4.94
5.36
1.1
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
12
26
4.94
5.36
1.7
1.5
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
8
6
14.00
5.14
1.1
1.3
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
8
6
14.00
5.14
2.5
1.3
—
—
—
0
0
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
8
6
14.00
5.14
2.5
1.3
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
13
32
4.36
5.01
1.5
1.1
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
79
515
2.16
4.98
27.5
8.7
e9/l
0.1
0.0
0.57
71
423
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
20
68
3.25
4.94
1.3
1.4
—
—
—
0
0
(40768441) Liver Pathology biopsy report
9
10
9.50
4.85
2.3
1.0
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
9
11
8.63
4.63
2.0
1.6
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
7
5
14.60
4.62
1.1
3.0
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
7
5
14.60
4.62
1.1
3.0
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
7
5
14.60
4.62
4.3
2.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
106
790
2.25
4.58
6.5
4.1
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
8
8
10.49
4.58
2.7
1.9
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
11
26
4.49
4.44
4.4
3.5
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
9
12
7.91
4.42
1.4
1.2
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
31
143
2.48
4.38
9.6
6.0
mmol/l
103.1
103.9
0.37
31
138
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
7
6
12.16
4.32
2.7
1.3
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
7
6
12.16
4.32
2.7
1.3
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
31
145
2.44
4.25
3.4
2.0
%
1.6
1.5
0.30
25
129
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
11
27
4.32
4.24
4.2
1.4
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
9
13
7.29
4.23
4.3
1.8
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
9
13
7.29
4.23
4.3
1.8
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
9
13
7.29
4.23
4.3
1.8
—
—
—
0
0
(3019060) Gas panel - Arterial blood
20
75
2.93
4.19
4.0
10.6
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
29
134
2.45
4.08
7.0
9.9
mmol/l
1.0
1.4
0.21
24
107
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.42
4.05
5.3
2.4
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.42
4.05
5.3
2.4
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.42
4.05
5.3
2.4
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.42
4.05
5.3
2.4
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
9
14
6.77
4.05
1.1
1.8
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
31
149
2.37
4.00
2.9
1.6
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
52
310
2.05
3.95
4.9
2.9
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
17
60
3.07
3.94
6.5
5.4
mmol/l
25.1
24.6
0.17
17
60
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
16
55
3.14
3.87
8.0
16.8
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
16
55
3.14
3.87
2.7
1.5
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
17
61
3.02
3.84
6.6
7.8
mmol/l
23.8
24.7
0.39
17
56
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
10
25
4.22
3.76
1.2
1.4
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
14
45
3.34
3.76
4.9
2.3
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
9
16
5.92
3.72
4.9
1.7
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
44
254
2.05
3.60
2.2
1.4
nmol/l
17.5
22.2
1.35
44
214
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
9
17
5.56
3.57
4.9
1.6
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
8
13
6.44
3.55
1.1
1.2
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
35
186
2.16
3.55
3.5
2.8
e6/l
2.1
1.4
0.33
16
105
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
6
6
10.35
3.53
2.2
1.8
—
—
—
0
0
(3017704) Immunofixation for Urine
6
6
10.35
3.53
1.2
1.2
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
6
6
10.35
3.53
5.8
2.3
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
6
6
10.35
3.53
5.8
2.3
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
6
6
10.35
3.53
2.2
1.8
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
6
6
10.35
3.53
5.8
2.3
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
6
6
10.35
3.53
6.5
1.3
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
43
248
2.04
3.52
1.3
1.3
u/ml
1.0
0.9
0.13
12
78
(3049717) Cytology report of Urine Cyto stain
13
42
3.30
3.46
1.5
2.7
—
—
—
0
0
(3023420) DNA double strand Ab [Units/volume] in Serum
7
10
7.28
3.40
1.3
1.1
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
17
66
2.78
3.35
4.2
2.5
%
1.9
1.4
0.37
17
66
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
6
7
8.87
3.29
1.0
1.1
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
18
73
2.67
3.27
1.8
1.2
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
9
20
4.72
3.17
4.2
2.0
%
49.0
58.8
—
9
20
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
6
8
7.76
3.08
2.3
1.6
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
12
40
3.18
3.05
2.6
1.5
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
25
446
0.47
3.02
3.8
2.8
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
8
17
4.91
2.96
5.0
1.4
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
8
17
4.91
2.96
5.0
1.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
22
104
2.31
2.93
5.3
3.5
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
9
6.89
2.89
2.2
1.8
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
36
3.22
2.87
1.2
1.2
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
8
18
4.64
2.84
5.0
1.4
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
8
18
4.64
2.84
5.0
1.4
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
8
18
4.64
2.84
5.0
1.4
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
8
18
4.64
2.84
5.0
1.4
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
9
23
4.10
2.82
8.4
2.5
kpa
7.5
8.4
—
9
23
(3013290) Carbon dioxide [Partial pressure] in Blood
9
23
4.10
2.82
8.4
2.5
kpa
4.8
4.8
—
9
23
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
35
203
1.95
2.78
3.3
2.5
e6/l
0.7
0.9
0.41
17
121
(3042631) Mycobacterium sp identified in Specimen
7
14
5.19
2.76
1.9
2.3
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
6
10
6.20
2.72
1.0
1.1
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
63
443
1.74
2.69
6.1
3.7
ng/l
25.9
38.5
0.73
51
300
(3012516) Albumin [Mass/volume] in Urine
49
322
1.79
2.63
3.6
3.4
mg/l
2852.7
92.0
0.84
34
220
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
104
845
1.80
2.63
4.4
3.8
pmol/l
14.5
14.9
0.97
96
773
(44790047)
7
15
4.84
2.63
2.0
1.6
—
—
—
0
0
(44790048)
7
15
4.84
2.63
2.0
1.6
—
—
—
0
0
(44790049)
7
15
4.84
2.63
2.0
1.6
—
—
—
0
0
(44806118)
7
15
4.84
2.63
2.0
1.6
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
9
25
3.77
2.62
1.6
1.1
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
5
7
7.34
2.57
1.4
1.1
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
5
7
7.34
2.57
1.2
1.4
—
—
—
0
0
(1616796) Gas panel - Central venous blood
9
26
3.62
2.53
7.7
2.8
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
12
45
2.82
2.52
3.2
1.9
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
47
310
1.76
2.47
1.6
1.4
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
19
91
2.25
2.46
3.2
2.4
ug/l
17.3
9.4
0.35
13
83
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
9
27
3.48
2.44
2.4
1.4
—
—
—
0
0
(3018572) Chloride [Moles/volume] in Blood
8
22
3.78
2.40
6.8
27.6
mmol/l
106.3
106.0
—
8
22
(3039000) Anion gap in Blood
8
22
3.78
2.40
6.8
27.6
mmol/l
11.4
10.7
—
8
22
(3023419) Bacteria identified in Sputum by Culture
7
17
4.27
2.39
2.4
3.2
—
—
—
0
0
(3022145) Colonoscopy Study observation
24
130
2.01
2.29
1.4
1.4
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
5
9
5.71
2.23
1.2
1.3
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
50
346
1.68
2.18
4.9
4.2
mg/mmol
35.9
13.7
0.67
36
234
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
31
189
1.81
2.10
1.3
1.2
u/ml
46.1
5.6
—
8
78
(21494890) Protein electrophoresis panel - 24 hour Urine
5
10
5.13
2.08
1.2
1.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
20
106
2.03
2.03
1.5
1.6
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
51
2.47
2.01
2.9
2.1
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
5
11
4.66
1.95
1.2
1.4
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
5
11
4.66
1.95
1.0
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
5
11
4.66
1.95
1.0
1.2
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
5
11
4.66
1.95
1.0
1.2
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
5
11
4.66
1.95
1.0
1.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
5
11
4.66
1.95
1.0
1.2
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
5
11
4.66
1.95
1.0
1.2
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
9
34
2.75
1.90
4.6
2.9
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
132
1197
2.07
1.85
49.0
13.6
mg/l
21.6
24.2
0.58
126
940
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
32
205
1.72
1.83
1.5
1.2
iu/ml
150.4
35.1
0.45
11
66
(3035350) Ketones [Presence] in Urine by Test strip
73
574
1.54
1.81
5.1
3.3
estimate
0.0
0.0
0.00
21
122
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
32
207
1.70
1.77
5.1
3.6
ng/l
706.5
265.7
0.28
27
161
(3021901) Oxygen saturation in Capillary blood
7
24
3.01
1.74
4.1
2.7
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
48
346
1.58
1.73
3.8
3.2
mmol/l
6.5
8.3
3.02
42
296
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
13
3.94
1.73
1.2
1.1
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
5
13
3.94
1.73
1.2
1.2
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
13
3.94
1.73
1.2
1.1
—
—
—
0
0
(3013512) EKG study
45
321
1.58
1.70
6.2
3.9
—
—
—
0
0
(3002256) Pathology report gross observation
22
130
1.82
1.64
1.0
1.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
60
462
1.51
1.59
2.2
2.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
5
15
3.41
1.53
4.0
1.8
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
72
579
1.48
1.53
5.1
3.3
estimate
0.0
0.0
0.00
20
113
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
6
21
2.93
1.52
2.7
1.1
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
45
329
1.53
1.51
3.3
2.0
u/l
96.5
253.5
1.97
45
312
(3029937) Albumin [Presence] in Urine by Test strip
44
321
1.53
1.49
6.5
3.3
estimate
0.0
0.0
0.00
18
117
(3011397) Hemoglobin [Presence] in Urine by Test strip
36
251
1.58
1.48
4.5
3.1
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
71
574
1.46
1.45
6.2
4.5
estimate
0.0
0.0
0.00
20
122
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
7
29
2.48
1.41
1.4
1.4
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
123
1115
1.65
1.40
39.2
12.6
ml/min/173m2
80.2
82.7
0.46
104
917
(3044290) Cell count panel - Cerebral spinal fluid
6
23
2.68
1.38
1.3
1.5
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
13
69
1.97
1.33
1.2
1.2
iu/ml
28.8
139.6
—
5
23
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
5
18
2.84
1.29
2.0
2.1
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
5
18
2.84
1.29
9.8
3.0
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
16
94
1.79
1.23
2.9
2.7
ml/min/173m2
45.0
67.2
—
8
39
(40768443) Skin Pathology biopsy report
10
50
2.07
1.19
1.1
1.1
—
—
—
0
0
(3020891) Body temperature
10
50
2.07
1.19
4.5
4.1
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
113
0.42
1.18
1.4
1.6
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
8
39
2.11
1.17
1.5
1.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
9
160
0.53
1.06
1.7
1.5
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
32
0.00
0.96
0.0
1.5
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
6
27
2.27
0.94
1.8
1.5
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
11
64
1.78
0.89
1.5
1.2
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
109
1172
0.72
0.88
5.2
4.3
mmol/l
1.2
1.4
8.70
102
1090
(3000492) Spirometry study
18
121
1.56
0.88
2.6
1.5
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
106
1141
0.74
0.82
5.6
3.9
mmol/l
1.4
1.3
0.96
98
1056
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
6
33
1.85
0.80
1.2
1.1
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
114
1058
1.35
0.76
5.6
4.4
mu/l
2.2
1.9
1.25
106
974
(40761535) Cells panel - Urine sediment
14
93
1.56
0.72
5.2
3.3
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
113
1199
0.75
0.71
5.5
4.8
mmol/l
2.3
2.8
5.80
107
1113
(3011288) Drugs identified in Urine by Screen method
5
27
1.88
0.69
1.6
2.1
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
111
1178
0.76
0.67
5.3
4.3
mmol/l
4.1
4.6
7.25
105
1104
(3041096) Erythrocytes [Presence] in Urine by Automated
41
338
1.30
0.66
4.9
3.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
116
1088
1.32
0.65
47.7
14.3
%
37.7
40.7
2.74
85
819
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
54
464
1.26
0.63
5.8
3.4
—
—
—
0
0
(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum
0
21
0.00
0.60
0.0
1.0
—
26.4
—
0
5
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
21
0.00
0.60
0.0
3.5
—
18.2
—
0
21
(42529406) Shigella sp [Presence] in Stool by Culture
6
35
1.74
0.58
1.8
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
6
35
1.74
0.58
1.8
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
6
35
1.74
0.58
1.8
1.2
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
15
107
1.45
0.58
8.4
3.5
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
9
134
0.65
0.55
1.1
1.4
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
8
60
1.35
0.41
1.8
1.3
—
—
—
0
0
(3044889) 12 lead EKG panel
89
831
1.18
0.41
5.1
3.7
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
30
254
1.23
0.40
5.7
3.3
kg/l
1.0
1.0
—
5
29
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
9
121
0.73
0.37
1.9
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
77
0.64
0.37
1.2
1.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
12
92
1.33
0.33
1.2
1.2
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
129
1256
1.23
0.29
46.4
12.5
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
113
1092
1.15
0.26
8.5
5.6
mmol/mol
40.0
40.0
0.00
102
1037
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
9
75
1.21
0.25
1.2
1.2
—
20.1
—
0
5
(3003338) MCHC [Mass/volume]
99
1029
0.88
0.25
58.6
17.3
g/l
331.1
333.3
1.01
99
1024
(3000764) Benzodiazepines [Presence] in Urine
5
37
1.36
0.24
4.0
1.5
—
—
—
0
0
(4010399)
12
97
1.26
0.23
1.4
1.4
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
5
38
1.33
0.23
4.0
1.4
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
5
38
1.33
0.23
4.2
1.4
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
5
39
1.29
0.23
4.0
1.4
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
5
39
1.29
0.23
4.2
1.5
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
9
114
0.78
0.21
1.6
1.6
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
23
203
1.16
0.20
2.0
1.5
—
—
—
0
0
(3008898) HLA-B27 [Presence]
6
51
1.18
0.19
1.0
1.0
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
79
755
1.10
0.19
4.1
3.1
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
12
135
0.88
0.10
14.2
7.9
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
116
1141
1.08
0.10
6.2
4.4
mmol/l
6.4
6.0
1.55
110
1053
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
34
359
0.93
0.09
4.0
4.3
%
21.6
20.2
0.16
13
176
(3045414) Leukocytes [Presence] in Urine
6
55
1.09
0.09
1.7
1.5
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
5
60
0.83
0.08
1.0
1.0
—
—
—
0
0
(3022621) pH of Urine by Test strip
7
82
0.85
0.07
2.3
2.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
13
139
0.93
0.03
1.8
1.9
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
13
129
1.01
0.00
1.4
1.8
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
27
268
1.01
0.00
3.0
2.9
ug/l
0.7
0.7
0.06
19
175
(3017446) Testosterone [Moles/volume] in Serum or Plasma
11
115
0.95
0.00
2.3
2.2
nmol/l
11.2
13.3
0.48
11
108
(3044242) Glucose [Moles/volume] in Arterial blood
0
8
0.00
0.00
0.0
1.7
—
—
—
0
0
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003329) Lymphocytes/100 leukocytes in Synovial fluid
0
7
0.00
0.00
0.0
1.3
—
30.1
—
0
7
(3037826) lamoTRIgine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
19.3
—
0
5
(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
2.4
—
43.6
—
0
7
(3034426) Prothrombin time (PT)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4211845)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004451) EKG impression Narrative
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(4024509)
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_HYPERSPLENISM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_HYPERSPLENISM | 6.062 [3.72, 9.87] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.274 |
During the follow-up period (1.1.1998 — 31.12.2019), 136 out of 361 females with D3_HYPERSPLENISM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_HYPERSPLENISM | 4.648 [3.31, 6.52] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 174 out of 469 males with D3_HYPERSPLENISM died.
Mortality risk
Mortality risk for people of age
years, who have D3_HYPERSPLENISM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.658% | 0.829% |
| 5 | 3.469% | 5.303% |
| 10 | 8.399% | 13.102% |
| 15 | 16.608% | 22.798% |
| 20 | 27.309% | 36.245% |
Relationships between endpoints
↥Index endpoint: D3_HYPERSPLENISM – Hypersplenism
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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