Hereditary hypogammaglobulinemia

D3_HEREDHYPOGAMMA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D80.0
  • Hospital discharge: ICD-9 2790A
  • Cause of death: ICD-10 D80.0
  • Cause of death: ICD-9 2790A

2 out of 7 registries used, show all original rules.

128

4. Check minimum number of events

None

128

5. Include endpoints

None

128

6. Filter based on genotype QC (FinnGen only)

128

Control definitions (FinnGen only)

Control exclude
D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D80
Name in latin
Hypogammaglobulinaemia hereditaria

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 605 359 244
Only index persons 530 325 205
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 42.72 45.82 38.04
Only index persons 42.31 45.45 37.32

-FinnGen-

Key figures

All Female Male
Number of individuals 128 80 48
Unadjusted period prevalence (%) 0.02 0.03 0.02
Median age at first event (years) 45.89 47.16 43.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
113
Matched controls
1128
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
149.9
108
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
67.6
58
*
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
63.7
55
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
58.5
51
*
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
42.4
38
*
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
36.4
33
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
20.2
31.1
49
41
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
30.6
28
*
ZX120
NOMESCO Finland
Intravenous
15.5
27.7
49
53
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
25.5
26.2
37
21
J01MA12
ATC
levofloxacin; systemic
10.7
26.2
60
108
WW200
NOMESCO Finland
Immunization
42.0
25.3
31
10
H02AB06
ATC
prednisolone; systemic
9.6
24.4
93
367
J01MA14
ATC
moxifloxacin; systemic
14.3
24.4
44
48
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
28.6
22.3
30
14
TPH04
NOMESCO Finland
Cathetrisation of vein
8.1
21.7
60
138
TDM10
NOMESCO Finland
Puncture of maxillary antrum
23.2
21.6
31
18
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.8
19.9
80
297
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
30.2
19.7
26
11
6BA02
NOMESCO Finland
NA
+∞
19.3
18
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
15.5
19.1
32
28
J47
ICD-10 Finland
Bronchiectasis
54.0
19.0
22
5
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
16.0
18.8
31
26
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
15.8
17.6
29
24
J18.9
ICD-10 Finland
Pneumonia, unspecified
7.0
17.6
51
118
R50.9
ICD-10 Finland
Fever, unspecified
8.1
17.3
43
79
Z3231
NOMESCO Finland
Registered nurse
6.2
17.2
58
163
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
17.1
16
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
14.0
16.7
29
27
J01FA06
ATC
roxithromycin; oral
5.7
16.6
80
338
J45.9
ICD-10 Finland
Asthma, unspecified
6.8
16.5
48
110
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
16.0
15
*
C01CA24
ATC
epinephrine; parenteral
9.5
15.7
34
49
J01.0
ICD-10 Finland
Acute maxillary sinusitis
5.7
15.5
56
166
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.6
15.2
56
169
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
11.1
14.9
29
34
H02AB07
ATC
prednisone; oral
6.6
14.2
41
90
R4110
NOMESCO Finland
Physiotherapy
5.3
14.1
53
161
Z3226
NOMESCO Finland
Physiotherapist
6.1
13.9
43
103
TGC00
NOMESCO Finland
Bronchial lavation
26.4
13.4
18
8
J32.4
ICD-10 Finland
Chronic pansinusitis
79.0
12.9
14
*
Z01.8
ICD-10 Finland
Other specified special examinations
5.0
12.9
50
154
R03AC13
ATC
formoterol; inhalant
13.4
12.7
22
20
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.1
12.5
29
46
J01FA10
ATC
azithromycin; systemic
5.1
12.3
93
538
Z2446
NOMESCO Finland
Social worker
12.1
12.2
22
22
R03AK06
ATC
salmeterol and fluticasone; inhalant
5.8
11.9
37
87
R03DC03
ATC
montelukast; oral
5.3
11.7
40
105
UDH02
NOMESCO Finland
Rhinopharyngoscopy
8.1
11.7
27
42
J01FA09
ATC
clarithromycin; systemic
4.3
11.7
62
251
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
133.0
11.7
12
*
J45.1
ICD-10 Finland
Nonallergic asthma
8.3
11.5
26
39
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
4.9
11.5
43
125
N02AX02
ATC
tramadol; systemic, rectal
4.1
11.4
68
303
R03BA02
ATC
budesonide; inhalant
5.1
11.4
41
114
J01FA15
ATC
telithromycin; oral
6.0
11.3
33
72
ZXE10
NOMESCO Finland
More than one and less than three hours
4.1
11.2
63
266
J01MA02
ATC
ciprofloxacin; systemic
4.1
11.2
63
266
H02AB04
ATC
methylprednisolone; systemic
5.5
11.2
36
88
J45.0
ICD-10 Finland
Predominantly allergic asthma
6.9
11.1
29
54
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.7
11.1
44
135
M05BA04
ATC
alendronic acid; oral
10.9
11.1
21
23
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.7
11.0
34
79
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
120.8
10.6
11
*
2790A
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[AGAMMAGLOBULINAEMIA (BRUTON)]
+∞
10.6
10
*
A07AA02
ATC
nystatin; oral
9.3
10.2
21
27
A46
ICD-10 Finland
Erysipelas
6.0
10.1
29
61
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
22.5
10.1
14
7
Z2221
NOMESCO Finland
Medical doctor
4.0
9.7
48
176
R03AC12
ATC
salmeterol; inhalant
12.3
9.7
17
16
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
+∞
9.5
9
*
ZXA00
NOMESCO Finland
Right side
4.0
9.5
47
172
R03BB04
ATC
tiotropium bromide; inhalant
6.4
9.3
25
48
J01DA06
ATC
[U] cefuroxime; systemic
4.7
9.3
34
94
JN4BD
NOMESCO Finland
Extensive body CT
6.1
9.3
26
53
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
4.9
9.2
32
84
R03BB01
ATC
ipratropium bromide; inhalant
20.7
9.2
13
7
R03DA04
ATC
theophylline; systemic, rectal
10.9
9.2
17
18
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
7.1
9.0
22
37
ZXD20
NOMESCO Finland
Day surgery
5.2
9.0
29
70
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.3
9.0
24
46
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.5
8.9
54
233
XF400
NOMESCO Finland
ECG with 12 standard connections
4.5
8.7
33
94
X59
ICD-10 Finland
Exposure to unspecified factor
4.1
8.6
37
119
H04.10
ICD-10 Finland
Dry eye syndrome
5.5
8.6
26
58
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
4.1
8.5
37
120
A28
ICPC
Limited function/disability NOS
6.1
8.5
23
45
J06BA02
ATC
immunoglobulins, normal human, for intravascular adm.; systemic
+∞
8.4
8
*
M36.8*D80.1
ICD-10 Finland
Systemic disorders of connective tissue in hypogammaglobulinaemia
+∞
8.4
8
*
D86.0
ICD-10 Finland
Sarcoidosis of lung
+∞
8.4
8
*
D83.8
ICD-10 Finland
Other common variable immunodeficiencies
+∞
8.4
8
*
J01FF01
ATC
clindamycin; systemic
3.5
8.3
49
203
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
7.6
8.3
19
29
H02AB09
ATC
hydrocortisone; systemic
19.0
8.3
12
7
R03AK07
ATC
formoterol and budesonide; inhalant
3.8
8.1
39
138
ZX112
NOMESCO Finland
Subcutaneous
14.5
8.1
13
10
R01AD09
ATC
mometasone; nasal
3.2
7.9
72
403
J46
ICD-10 Finland
Status asthmaticus
11.2
7.8
14
14
R03BA05
ATC
fluticasone; inhalant
3.7
7.7
37
130
B01AB05
ATC
enoxaparin; parenteral
3.5
7.7
43
168
J02AC01
ATC
fluconazole; systemic
3.1
7.6
65
343
ZXE00
NOMESCO Finland
One hour or less
3.1
7.6
59
296
WX002
NOMESCO Finland
Sedation and analgesia
4.0
7.5
32
101
A01AB09
ATC
miconazole; local oral
5.1
7.5
24
57
R01AD05
ATC
budesonide; nasal
6.5
7.5
19
34
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.9
7.5
33
108
R01AD08
ATC
fluticasone; nasal
3.2
7.5
52
239
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.8
7.4
25
63
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
8.9
7.4
15
19
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
+∞
7.4
7
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
+∞
7.4
7
*
R06.0
ICD-10 Finland
Dyspnoea
3.5
7.3
39
148
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.1
7.3
23
54
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.1
7.2
19
36
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
7.2
44
185
J01DA08
ATC
[U] cefaclor; oral
4.4
7.1
26
71
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
15.0
7.1
11
8
J05AB01
ATC
aciclovir; systemic
3.5
7.0
37
138
N03AX16
ATC
pregabalin; oral
3.4
7.0
40
158
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
10.3
7.0
13
14
TAB00
NOMESCO Finland
Lumbar puncture
8.1
7.0
15
21
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
3.0
6.9
74
442
UJF32
NOMESCO Finland
Coloscopy
3.3
6.9
40
161
R03AC02
ATC
salbutamol; inhalant
2.9
6.8
77
475
J01AA02
ATC
doxycycline; systemic
3.9
6.8
99
729
J01DA01
ATC
[U] cefalexin; systemic
3.1
6.7
85
562
R03AK11
ATC
formoterol and fluticasone; inhalant
13.4
6.7
11
9
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.2
6.7
26
75
R03BA08
ATC
ciclesonide; inhalant
5.0
6.7
21
49
R06AE07
ATC
cetirizine; oral
2.8
6.6
65
368
XW000
NOMESCO Finland
Bone marrow biopsy
9.0
6.5
13
16
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
15.5
6.5
10
7
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
4.0
6.5
27
83
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.1
6.5
17
32
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
10.2
6.5
12
13
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
12.0
6.4
11
10
C10AC01
ATC
colestyramine; oral
12.0
6.4
11
10
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.5
6.4
16
28
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.3
6.4
24
67
P01AB01
ATC
metronidazole; oral, rectal
2.8
6.4
61
333
S18
ICPC
Laceration/cut
2.8
6.4
56
291
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.9
6.3
27
85
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
+∞
6.3
6
*
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
6.3
6
*
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
+∞
6.3
6
*
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
+∞
6.3
6
*
GD1DG
NOMESCO Finland
Extremely extensive MRI examination of pleura with high field magnet
+∞
6.3
6
*
132
Kela drug reimbursment
Sarcoidosis
+∞
6.3
6
*
J01.1
ICD-10 Finland
Acute frontal sinusitis
13.6
6.2
10
8
R01AD01
ATC
beclometasone; nasal
3.6
6.2
29
99
ZXD10
NOMESCO Finland
Scheduled procedure
2.8
6.1
55
287
C03CA01
ATC
furosemide; systemic
3.3
6.1
33
125
R03BA01
ATC
beclometasone; inhalant
3.7
6.1
27
88
J01DC02
ATC
cefuroxime; systemic
6.5
6.1
15
26
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
16.1
6.0
9
6
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
16.1
6.0
9
6

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3028026) IgM [Mass/volume] in Serum or Plasma
78
67
28.24
84.96
4.3
1.5
g/l
0.9
1.2
1.86
62
61
(3023419) Bacteria identified in Sputum by Culture
34
11
41.73
53.46
4.5
2.3
—
—
—
0
0
(4062490)
25
10
30.83
36.19
2.4
1.2
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
84
245
8.06
31.10
4.4
1.3
g/l
1.7
2.4
2.76
61
151
(42870588) Differential panel, method unspecified - Blood
100
362
9.06
29.14
19.7
5.6
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
36
61
7.82
21.80
2.4
1.8
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
27
33
10.10
21.35
3.1
1.5
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
68
217
5.55
21.08
9.9
4.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
50
125
5.92
20.42
3.6
2.5
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
52
137
5.71
19.98
3.7
1.8
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
22
22
11.87
19.95
1.5
1.2
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
24
30
9.62
18.54
2.9
2.9
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
36
75
6.29
17.64
6.4
6.0
%
0.6
0.3
0.76
13
24
(3021440) Promyelocytes/100 leukocytes in Blood
36
75
6.29
17.64
6.9
6.2
%
0.1
0.1
0.33
16
29
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
41
98
5.68
17.32
2.8
1.4
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
37
81
6.02
17.18
6.8
5.9
%
0.7
0.8
0.07
16
32
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
20
22
10.59
16.89
2.6
2.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
44
115
5.31
16.75
2.5
1.6
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
40
97
5.54
16.57
2.8
1.5
—
—
—
0
0
(40758558) Short blood count panel - Blood
69
262
4.54
16.34
17.0
6.6
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
19
21
10.45
15.96
2.6
2.0
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
94
460
4.93
15.57
25.4
8.7
e9/l
0.0
0.0
0.50
81
368
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
17
17
11.38
15.25
1.9
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
18
20
10.31
15.03
2.4
2.1
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
92
455
4.63
14.71
10.8
8.0
mmol/l
1.2
1.2
1.04
84
383
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
17
18
10.74
14.66
2.7
1.9
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
32
74
5.43
13.80
7.5
6.2
%
0.0
0.0
0.49
12
25
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
17
6
32.30
13.34
3.5
1.0
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
17
6
32.30
13.34
3.5
1.0
—
—
—
0
0
(3000991) Gas panel - Venous blood
30
69
5.37
12.97
10.1
9.7
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
57
216
3.95
12.96
4.0
2.2
mg/l
3.2
3.0
0.25
57
190
(3007853) Bacteria identified in Skin by Aerobe culture
38
107
4.63
12.92
2.5
1.6
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
37
103
4.65
12.75
7.8
8.3
mmol/l
1.1
1.1
0.07
37
96
(3021447) Carbon dioxide [Partial pressure] in Venous blood
31
75
5.13
12.64
5.7
4.5
kpa
6.0
5.8
0.23
31
75
(3018418) pH of Serum or Plasma
64
270
3.74
12.29
8.0
4.3
ph
7.4
7.4
0.64
15
54
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
16
20
9.00
12.16
1.6
1.7
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
17
23
8.37
12.15
10.6
4.8
%
53.9
57.9
0.43
17
23
(3030905) Polymorphonuclear cells [#/volume] in Blood
17
23
8.37
12.15
10.0
3.8
e9/l
3.3
4.9
1.07
17
23
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
16
8
22.58
11.46
5.1
3.0
—
—
—
0
0
(3000492) Spirometry study
36
108
4.25
11.15
3.5
1.3
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
13
14
10.22
10.95
3.8
1.7
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
13
14
10.22
10.95
3.8
1.7
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
13
14
10.22
10.95
3.8
1.7
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
14
18
8.61
10.35
1.6
1.0
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
14
18
8.61
10.35
1.6
1.0
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
12
13
10.08
10.03
2.9
1.7
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
23
52
5.17
10.02
2.1
1.6
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
60
271
3.29
9.89
5.2
2.8
e6/l
0.2
0.4
0.73
50
191
(3018677) aPTT in Platelet poor plasma by Coagulation assay
40
140
3.70
9.87
2.6
1.9
s
28.5
29.0
0.28
40
135
(3032080) INR in Blood by Coagulation assay
72
363
3.25
9.84
9.6
6.2
inr
1.2
1.1
0.06
25
106
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
11
11
10.85
9.68
2.8
1.8
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
12
14
9.35
9.50
4.1
1.7
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
55
241
3.25
9.46
2.1
1.7
mg/l
0.9
1.4
0.56
49
189
(3018095) Leukocytes [#/volume] in Urine
70
355
3.14
9.34
6.3
3.3
e6/l
34.4
51.0
0.25
55
243
(3013826) Glucose [Moles/volume] in Serum or Plasma
95
576
3.52
9.30
9.3
4.8
mmol/l
7.1
6.5
1.29
95
527
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
12
15
8.72
9.01
4.1
1.7
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
12
15
8.72
9.01
4.1
1.7
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
21
48
5.04
9.00
11.4
6.4
mmol/l
24.9
25.6
0.23
21
48
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
20
44
5.20
8.94
2.1
1.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
58
270
3.10
8.90
5.2
2.7
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
22
53
4.80
8.87
2.0
1.9
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
13
8
17.89
8.76
4.6
2.1
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
14
22
7.02
8.72
3.6
1.6
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
40
152
3.37
8.59
6.9
3.9
mmol/l
0.8
0.8
2.21
40
145
(3000850) Epithelial cells [#/volume] in Urine
47
198
3.17
8.50
5.2
2.5
e6/l
4.5
4.8
0.06
42
171
(3026008) Bacteria identified in Urine by Culture
57
271
2.99
8.31
4.7
2.6
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
68
357
2.93
8.25
6.0
2.9
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
12
7
18.72
8.25
1.6
2.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
61
310
2.85
7.75
6.0
2.8
e6/l
13.0
45.3
1.02
51
229
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
27
87
3.67
7.38
4.2
3.4
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
7
0
+∞
7.36
1.4
0.0
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
10
13
8.26
7.22
1.1
1.2
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
11
8
14.88
7.03
5.4
2.1
—
—
—
0
0
(4035726)
27
91
3.49
6.88
1.6
1.4
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
62
336
2.64
6.73
3.9
2.5
—
—
—
0
0
(3037121) Protein [Mass/volume] in Urine
15
33
5.02
6.65
2.1
3.9
g/l
0.5
0.2
—
10
16
(3003396) Base excess in Arterial blood by calculation
26
88
3.45
6.57
10.0
13.4
mmol/l
1.6
1.3
0.09
20
72
(3023520) Reticulocytes [#/volume] in Blood
23
72
3.68
6.52
5.8
2.5
e9/l
77.4
74.0
0.10
17
54
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
10
15
7.15
6.41
3.3
1.8
—
—
—
0
0
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
11
19
6.24
6.22
1.1
1.2
mg/l
386.2
432.3
0.36
11
19
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
13
27
5.25
6.12
1.1
1.2
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
12
24
5.41
5.87
1.1
1.0
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
37
4.46
5.81
2.3
1.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
16
42
4.21
5.74
11.9
21.4
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
21
69
3.44
5.52
3.4
4.9
ng/l
76.6
83.6
0.21
21
63
(3028433) Virus identified in Specimen by Culture
8
5
16.92
5.48
2.3
1.0
—
—
—
0
0
(44790049)
8
5
16.92
5.48
1.3
1.8
—
—
—
0
0
(44790047)
8
5
16.92
5.48
1.3
1.8
—
—
—
0
0
(44806118)
8
5
16.92
5.48
1.3
1.8
—
—
—
0
0
(44790048)
8
5
16.92
5.48
1.3
1.8
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
50
265
2.46
5.46
16.9
4.9
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
21
70
3.39
5.40
1.4
1.2
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
9
8
11.98
5.38
1.3
1.1
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
14
35
4.37
5.32
6.6
2.0
—
—
—
0
0
(3033799) Differential panel - Peritoneal fluid
5
0
+∞
5.24
3.0
0.0
—
—
—
0
0
(3013924) Clostridium tetani IgG Ab [Units/volume] in Serum
5
0
+∞
5.24
1.2
0.0
—
—
—
0
0
(3001964) Herpes simplex virus Ag [Presence] in Specimen
5
0
+∞
5.24
1.0
0.0
—
—
—
0
0
(3007566) Smooth muscle Ab [Titer] in Serum
13
31
4.55
5.23
1.5
1.2
—
58.0
—
0
5
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
75
482
2.34
5.22
5.6
4.4
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
72
457
2.32
5.13
2.3
2.1
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
18
56
3.58
5.12
9.8
4.6
kpa
5.1
5.1
0.15
18
49
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
34
154
2.64
5.11
3.9
2.5
e6/l
1.7
3.0
0.59
22
81
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
10
20
5.34
4.86
1.6
1.5
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
61
371
2.23
4.70
2.5
1.8
pmol/l
94.7
99.5
0.42
33
181
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
34
160
2.53
4.70
3.7
2.4
e6/l
0.9
0.9
0.09
22
86
(3035400) Alkaline phosphatase.liver [Enzymatic activity/volume] in Serum or Plasma
7
5
14.69
4.63
1.1
1.2
u/l
120.9
56.2
—
7
5
(4010399)
19
66
3.21
4.56
1.9
1.3
—
—
—
0
0
(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis
12
30
4.31
4.55
2.2
1.1
g/l
0.0
0.0
0.00
12
30
(3004119) Hemoglobin [Mass/volume] in Venous blood
16
51
3.44
4.38
2.5
3.6
g/l
121.8
130.5
0.50
16
51
(3024891) Influenza virus A+B Ag [Presence] in Specimen
13
36
3.91
4.33
1.2
1.1
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
10
23
4.63
4.17
1.3
1.3
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
33
162
2.40
4.13
1.8
1.4
titre
400.0
513.5
—
6
37
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
8
10
8.44
4.12
1.1
1.4
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
8
10
8.44
4.12
3.9
1.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
45
253
2.20
4.11
3.5
2.6
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.48
4.06
2.4
2.3
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.48
4.06
2.4
2.3
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.48
4.06
2.4
2.3
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
7
7
10.48
4.06
2.4
2.3
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
9
14
6.82
4.06
1.1
1.3
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
9
14
6.82
4.06
1.2
1.3
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
8
11
7.67
3.92
1.6
1.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
26
117
2.53
3.90
1.7
1.4
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
9
15
6.36
3.89
3.3
1.8
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
13
39
3.60
3.88
3.7
3.3
mmol/l
25.8
25.0
0.41
13
39
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
6
5
12.49
3.80
1.0
1.0
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
46
268
2.12
3.80
4.6
3.2
mg/l
116.9
62.3
0.30
26
159
(40768797) Stomach Pathology biopsy report
31
154
2.34
3.76
1.4
1.2
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
8
12
7.03
3.73
2.3
1.6
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
18
69
2.87
3.65
3.0
3.4
pmol/l
4.0
4.4
1.03
18
63
(3051611) Lipemic interference index of Serum or Plasma
7
9
8.14
3.60
3.6
1.4
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
47
281
2.06
3.60
5.4
3.9
mg/mmol
17.8
8.6
0.35
28
170
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
12
36
3.57
3.57
5.8
2.4
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
94
721
2.14
3.57
8.0
4.0
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
8
13
6.48
3.56
1.8
1.3
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
6
6
10.41
3.53
2.5
2.3
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
6
6
10.41
3.53
2.5
2.3
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
6
6
10.41
3.53
2.5
2.3
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
6
6
10.41
3.53
4.8
1.8
umol/l
25.2
29.5
—
6
6
(3051651) Icteric interference index of Serum or Plasma
6
6
10.41
3.53
3.7
1.2
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
32
166
2.24
3.50
4.9
3.1
ng/l
242.1
36.2
0.57
22
111
(46235355) HIV 1 and 2 tests - Meaningful Use set
35
189
2.17
3.47
2.1
1.8
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
10
27
3.93
3.42
1.8
2.1
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
7
10
7.33
3.41
2.4
2.2
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
7
10
7.33
3.41
1.7
1.1
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
7
10
7.33
3.41
2.4
2.2
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
7
10
7.33
3.41
2.4
2.2
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
8
14
6.01
3.39
1.6
1.3
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
13
43
3.25
3.36
3.1
3.8
%
54.8
50.7
0.19
13
43
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
6
7
8.91
3.30
1.3
1.0
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
11
33
3.55
3.27
1.4
1.3
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
10
28
3.79
3.26
2.4
1.1
g/l
0.0
0.0
—
10
28
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
10
28
3.79
3.26
2.4
1.1
g/l
0.0
0.0
—
10
28
(3021901) Oxygen saturation in Capillary blood
7
11
6.66
3.23
3.3
3.7
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
118
1013
3.11
3.21
34.7
11.5
ml/min/173m2
86.5
86.3
0.02
110
815
(3024928) Oxygen saturation in Venous blood
8
16
5.26
3.10
1.9
4.8
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
8
16
5.26
3.10
1.3
1.3
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
6
8
7.80
3.09
1.2
1.1
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
6
8
7.80
3.09
1.5
2.6
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
6
8
7.80
3.09
2.5
1.3
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
48
303
1.93
3.08
5.1
3.2
mmol/l
6.4
7.9
2.23
43
261
(3037756) Immunofixation for Serum or Plasma
7
12
6.10
3.06
1.0
1.3
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
110
920
2.39
3.04
48.7
15.0
%
14.2
13.6
3.70
110
909
(3034770) Mitochondria Ab [Titer] in Serum
11
35
3.34
3.01
1.6
1.1
—
—
—
0
0
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
5
5
10.33
3.00
2.2
1.6
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
7
13
5.63
2.91
1.1
7.7
—
—
—
0
0
(3022313) Gas panel - Capillary blood
12
42
3.05
2.83
12.3
4.8
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
12
42
3.05
2.83
2.9
2.8
%
0.6
0.6
0.14
12
42
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
13
48
2.90
2.81
11.8
11.2
%
0.5
0.6
1.37
13
48
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
13
48
2.90
2.81
12.2
10.8
%
0.9
1.4
1.50
13
48
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
5
6
8.60
2.77
1.0
1.3
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
6
10
6.23
2.73
1.0
1.0
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
6
10
6.23
2.73
1.3
1.1
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
6
11
5.66
2.57
2.0
1.1
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
5
7
7.37
2.57
4.8
2.1
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
11
39
2.99
2.54
12.3
5.3
mmol/l
25.2
24.3
0.37
11
39
(3019060) Gas panel - Arterial blood
13
51
2.72
2.53
6.3
13.6
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
12
45
2.84
2.53
3.0
2.7
%
2.3
1.2
0.79
12
45
(3008757) Leukocyte morphology finding [Identifier] in Blood
6
12
5.19
2.43
2.0
3.2
—
—
—
0
0
(4027681)
5
8
6.45
2.39
1.2
1.1
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
8
6.45
2.39
4.8
2.0
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
5
8
6.45
2.39
4.8
2.0
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
6
13
4.78
2.30
1.0
1.0
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
6
13
4.78
2.30
1.0
1.1
nmol/l
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
6
13
4.78
2.30
4.5
1.7
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
6
13
4.78
2.30
1.2
1.1
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
40
259
1.79
2.28
1.4
1.3
u/ml
0.4
1.8
—
8
70
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
5
9
5.73
2.23
1.0
1.0
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
17
82
2.24
2.18
1.6
1.6
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
6
14
4.44
2.17
1.0
1.1
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
5
10
5.15
2.09
1.0
1.0
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
5
10
5.15
2.09
5.0
1.8
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
5
10
5.15
2.09
3.2
1.7
%
89.8
90.0
—
5
10
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
7
20
3.64
2.08
2.0
1.3
—
—
—
0
0
(3044889) 12 lead EKG panel
88
720
1.71
2.07
4.4
3.5
—
—
—
0
0
(3000475) Leukocytes [#/volume] in Synovial fluid
6
15
4.14
2.06
3.5
1.4
e6/l
8861.0
4033.7
—
6
9
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
6
15
4.14
2.06
4.5
1.7
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
9
33
2.85
1.97
2.1
1.5
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
6
16
3.88
1.96
1.8
2.8
%
69.3
59.3
—
6
16
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
6
16
3.88
1.96
1.2
1.1
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
6
16
3.88
1.96
1.5
1.0
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
24
139
1.89
1.92
2.4
1.5
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
28
171
1.82
1.91
2.5
1.6
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
7
22
3.30
1.91
1.1
1.0
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
66
509
1.61
1.90
5.7
3.3
estimate
0.0
0.0
0.00
17
87
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
6
17
3.65
1.86
1.2
1.1
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
7
23
3.16
1.82
1.3
1.3
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
6
18
3.44
1.77
2.0
1.2
—
—
—
0
0
(1616796) Gas panel - Central venous blood
5
13
3.95
1.73
9.4
4.2
—
—
—
0
0
(3002256) Pathology report gross observation
25
152
1.80
1.73
1.2
1.2
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
18
99
1.95
1.67
1.2
1.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
15
77
2.07
1.67
7.1
4.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
10
43
2.44
1.65
1.3
1.3
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
144
0.39
1.64
1.5
1.7
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
10
44
2.38
1.57
9.5
4.0
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
65
516
1.53
1.56
8.3
4.6
estimate
0.0
0.0
0.00
17
88
(3009261) Glucose [Presence] in Urine by Test strip
65
518
1.52
1.52
5.8
3.3
estimate
0.0
0.0
0.00
17
87
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
9
37
2.54
1.51
1.3
1.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
33
226
1.62
1.49
3.7
3.0
—
—
—
0
0
(3020891) Body temperature
7
28
2.58
1.47
1.9
5.8
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
123
1156
2.64
1.46
31.1
11.5
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
6
22
2.81
1.45
1.2
1.1
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
14
75
1.97
1.41
3.1
3.1
ml/min/173m2
100.3
68.1
—
6
33
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
50
384
1.50
1.36
5.0
3.1
ng/l
26.0
24.3
0.08
41
234
(21494755) Public health laboratory ask at order entry panel
7
144
0.46
1.30
1.0
1.3
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
6
25
2.47
1.26
1.7
1.2
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
5
19
2.70
1.22
1.4
1.1
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
5
19
2.70
1.22
1.0
1.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
40
300
1.48
1.20
6.2
3.2
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
6
26
2.37
1.20
1.7
3.7
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
8
39
2.12
1.17
1.8
3.1
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
5
20
2.56
1.16
1.2
1.1
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
5
21
2.43
1.10
4.2
3.7
mmol/l
7.1
7.1
—
5
21
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
7
33
2.18
1.07
1.7
1.5
—
5706.0
—
0
10
(3045414) Leukocytes [Presence] in Urine
7
34
2.12
1.04
2.1
1.8
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
5
22
2.32
1.04
4.2
3.6
mmol/l
2.6
1.3
—
5
22
(1761868) Lipid panel - Serum or Plasma
34
440
0.69
1.04
3.4
2.6
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
6
27
2.28
0.95
13.0
4.6
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
103
0.46
0.94
1.2
1.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
27
200
1.44
0.86
1.6
1.4
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
34
266
1.38
0.80
5.8
3.6
estimate
0.0
0.0
0.00
17
86
(3050129) First trimester maternal screen panel - Serum or Plasma
0
25
0.00
0.80
0.0
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
14
91
1.60
0.79
2.0
1.4
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
5
23
2.22
0.77
1.6
2.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
7
39
1.84
0.74
1.6
2.9
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
7
41
1.75
0.71
1.4
1.2
—
—
—
0
0
(4094501)
5
27
1.89
0.69
1.0
1.1
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
8
49
1.67
0.63
1.5
2.7
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
7
115
0.59
0.61
8.9
6.0
—
—
—
0
0
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
0
20
0.00
0.61
0.0
1.3
—
7.7
—
0
13
(3000764) Benzodiazepines [Presence] in Urine
8
52
1.57
0.61
1.5
2.6
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
8
52
1.57
0.61
1.5
2.6
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
8
52
1.57
0.61
1.5
2.6
—
—
—
0
0
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
0
22
0.00
0.60
0.0
1.2
—
3.8
—
0
10
(3011288) Drugs identified in Urine by Screen method
6
36
1.70
0.57
2.0
4.1
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
9
134
0.65
0.55
6.2
4.1
%
36.6
31.4
—
9
87
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
48
416
1.25
0.53
6.4
3.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
33
275
1.27
0.50
1.4
1.4
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
84
782
1.22
0.44
4.7
3.0
u/l
58.5
45.1
0.80
84
739
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
8
55
1.48
0.44
1.6
1.5
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
(3008401) Mugwort IgE Ab [Units/volume] in Serum
0
16
0.00
0.41
0.0
1.1
—
1.0
—
0
9
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
18
0.00
0.40
0.0
2.9
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
9
66
1.39
0.39
1.8
1.5
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
18
144
1.29
0.38
1.7
1.6
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
7
52
1.37
0.32
1.6
1.9
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
28
242
1.20
0.31
1.6
1.5
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
83
785
1.16
0.31
4.2
3.3
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
22
257
0.83
0.30
5.1
4.7
ug/l
2.4
3.0
0.19
22
227
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
17
140
1.25
0.29
1.8
1.9
%
1.6
1.4
0.34
12
126
(1002224) Polysomnography panel
8
62
1.31
0.28
1.1
1.0
—
—
—
0
0
(40761535) Cells panel - Urine sediment
9
74
1.23
0.26
3.9
3.5
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
16
133
1.23
0.26
1.6
1.5
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
9
77
1.18
0.25
2.2
2.4
ug/l
7.6
5.0
—
9
65
(1617658) Protocol used for examination of sentinel lymph nodes
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
6
52
1.16
0.19
2.7
2.4
—
—
—
0
0
(3013512) EKG study
31
283
1.13
0.18
6.1
3.7
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
5
65
0.76
0.17
1.0
1.3
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
106
1035
1.14
0.17
43.7
13.0
%
40.3
40.6
0.21
85
813
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
9
109
0.81
0.13
1.8
1.7
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
19
210
0.89
0.13
1.2
1.2
u/ml
1.3
8.5
—
6
90
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
19
206
0.91
0.09
4.3
4.3
%
20.6
22.7
0.24
13
87
(3022621) pH of Urine by Test strip
5
61
0.81
0.08
2.2
2.0
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
5
60
0.83
0.08
1.4
1.3
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
21
206
1.02
0.00
1.3
1.3
iu/ml
12.3
54.6
—
7
70
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
13
131
0.99
0.00
1.3
1.5
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3034426) Prothrombin time (PT)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
17.5
—
0
5
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014271) Vancomycin [Susceptibility]
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3008898) HLA-B27 [Presence]
5
54
0.92
0.00
1.2
1.0
—
—
—
0
0
(40761847) Hazelnut recombinant (rCor a) 8 IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
0.0
—
0
5
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004451) EKG impression Narrative
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3014599) Egg white IgE Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3019225) pH of Specimen
9
91
0.99
0.00
7.6
5.3
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_HEREDHYPOGAMMA and mortality.

Females

Parameter HR [95% CI] p-value
D3_HEREDHYPOGAMMA 3.534 [2.19, 5.71] < 0.001
Birth year 0.991 [0.98, 1.0] 0.052

During the follow-up period (1.1.1998 — 31.12.2019), 61 out of 290 females with D3_HEREDHYPOGAMMA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have D3_HEREDHYPOGAMMA.

N-year risk Females Males
1 0.309% No data
5 1.859% No data
10 4.472% No data
15 8.584% No data
20 14.501% No data

Relationships between endpoints

Index endpoint: D3_HEREDHYPOGAMMA – Hereditary hypogammaglobulinemia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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