This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Hereditary factor XI deficiency
D3_HEREDFXIDEF
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
15 |
4. Check minimum number of eventsNone |
15 |
5. Include endpointsNone |
15 |
6. Filter based on genotype QC (FinnGen only) |
15 |
Control definitions (FinnGen only)
- Control exclude
- D3_COAGDEF_PURPUR_HAEMORRHAGIC
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D68
- Name in latin
- Deficientia hereditaria factoris XI
Similar endpoints
↥List of similar endpoints to
Hereditary factor XI deficiency
based on the number of shared cases.
Similar with more cases:
- Other coagulation defects
- Coagulation defects, purpura and other haemorrhagic conditions
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 123 | 78 | 44 |
| Only index persons | 109 | 74 | 35 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 34.15 | 35.50 | 31.13 |
| Only index persons | 33.19 | 34.11 | 31.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 15 | 11 | - |
| Unadjusted period prevalence (%) | 0.00 | 0.00 | - |
| Median age at first event (years) | 41.71 | 31.78 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3018677) aPTT in Platelet poor plasma by Coagulation assay
6
14
6.36
2.43
4.0
1.9
s
30.2
29.4
—
6
14
(3015736) pH of Urine
10
54
3.53
1.58
3.8
3.7
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
0
34
0.00
1.37
0.0
1.2
—
21.9
—
0
26
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
9
48
3.16
1.36
2.4
3.0
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
5
21
3.04
1.19
1.2
1.8
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
6
26
3.15
1.10
8.3
2.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
6
29
2.76
1.04
2.7
4.0
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
6
30
2.65
1.01
2.2
1.8
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
6
31
2.54
0.98
7.5
4.2
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
8
49
2.34
0.82
1.6
1.8
nmol/l
62.7
73.0
—
8
41
(3044640) Blood type and Crossmatch panel - Blood
7
43
2.17
0.81
2.3
2.0
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
9
58
2.37
0.78
10.1
3.3
e9/l
0.7
0.6
—
9
49
(3022096) Basophils/100 leukocytes in Blood
8
52
2.14
0.77
11.4
3.5
%
0.5
0.6
—
8
46
(3006315) Basophils [#/volume] in Blood
9
59
2.30
0.77
10.1
3.2
e9/l
0.0
0.0
—
9
50
(3019198) Lymphocytes [#/volume] in Blood
9
60
2.24
0.76
10.1
3.3
e9/l
2.1
1.9
—
9
55
(3035350) Ketones [Presence] in Urine by Test strip
10
68
2.40
0.76
3.9
3.8
—
0.0
—
0
16
(3009261) Glucose [Presence] in Urine by Test strip
10
69
2.34
0.76
3.9
3.8
—
0.0
—
0
15
(3021601) Nitrite [Presence] in Urine by Test strip
10
69
2.34
0.76
7.0
5.0
—
0.0
—
0
15
(3041096) Erythrocytes [Presence] in Urine by Automated
6
37
2.03
0.65
3.5
3.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
6
39
1.89
0.62
2.2
2.4
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
8
55
1.97
0.57
11.5
3.7
%
9.1
8.3
—
8
49
(3006504) Eosinophils/100 leukocytes in Blood
8
55
1.97
0.57
11.5
3.5
%
1.8
2.3
—
8
49
(3018010) Neutrophils/100 leukocytes in Blood
8
56
1.91
0.57
11.4
3.3
%
56.0
57.6
—
8
51
(3002030) Lymphocytes/100 leukocytes in Blood
8
57
1.86
0.56
11.4
3.5
%
24.8
30.0
—
8
51
(36304419) Bacteria [Presence] in Urine
5
35
1.64
0.44
2.4
2.2
—
—
—
0
0
(3013512) EKG study
5
35
1.64
0.44
2.8
4.5
—
—
—
0
0
(4035726)
0
15
0.00
0.44
0.0
1.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
7
52
1.64
0.40
3.1
3.8
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
7
53
1.60
0.39
2.7
2.2
—
—
—
0
0
(3044889) 12 lead EKG panel
7
90
0.59
0.39
1.9
3.2
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
9
73
1.58
0.37
10.7
4.8
umol/l
7.3
10.7
—
9
66
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
8
64
1.53
0.23
4.0
3.9
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
10
88
1.41
0.23
3.1
4.0
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
0
11
0.00
0.22
0.0
1.9
—
12.8
—
0
11
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
0
11
0.00
0.22
0.0
1.9
—
4.7
—
0
11
(3017732) Neutrophils [#/volume] in Blood
0
11
0.00
0.22
0.0
1.5
—
4.2
—
0
11
(4094501)
0
10
0.00
0.22
0.0
1.3
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
0
10
0.00
0.22
0.0
4.6
—
5.1
—
0
10
(3009343) pH of Capillary blood
0
10
0.00
0.22
0.0
4.6
—
—
—
0
0
(3022621) pH of Urine by Test strip
0
10
0.00
0.22
0.0
2.5
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
0
10
0.00
0.22
0.0
2.1
—
95.0
—
0
10
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
0
13
0.00
0.21
0.0
11.4
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
7
68
1.05
0.00
14.3
4.9
e9/l
0.1
0.0
—
7
54
(3028707) Methadone [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
0
5
0.00
0.00
0.0
1.6
—
215.6
—
0
5
(3019060) Gas panel - Arterial blood
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
5
52
0.94
0.00
4.6
2.3
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.7
—
82.8
—
0
6
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
72.5
—
0
6
(3000764) Benzodiazepines [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
0
6
0.00
0.00
0.0
2.5
—
122.5
—
0
6
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
31.8
—
0
5
(3027008) Opiates [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.3
—
112.8
—
0
6
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
7
0.00
0.00
0.0
6.0
—
24.0
—
0
7
(42529406) Shigella sp [Presence] in Stool by Culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020891) Body temperature
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
2.3
—
109.3
—
0
9
(3002523) Influenza virus A Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008152) Bicarbonate [Moles/volume] in Arterial blood
0
6
0.00
0.00
0.0
2.7
—
23.0
—
0
6
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
9
85
1.15
0.00
4.4
2.3
u/l
108.1
43.5
—
9
77
(3025130) Human papilloma virus identified in Specimen
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3022313) Gas panel - Capillary blood
0
7
0.00
0.00
0.0
5.4
—
—
—
0
0
(1002224) Polysomnography panel
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.9
—
18.7
—
0
9
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
53.7
—
0
7
(3003740) Influenza virus B Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3018405) Lactate [Moles/volume] in Arterial blood
0
5
0.00
0.00
0.0
1.8
—
1.0
—
0
5
(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_HEREDFXIDEF and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have D3_HEREDFXIDEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: D3_HEREDFXIDEF – Hereditary factor XI deficiency
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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