This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Common variable immunodeficiency with autoantibodies to B- or T-cells
D3_CVID_BT_CELL_AB
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
8 |
4. Check minimum number of eventsNone |
8 |
5. Include endpointsNone |
8 |
6. Filter based on genotype QC (FinnGen only) |
8 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D83
- Name in latin
- Deficientia immunalis variabilis communis cum autoanticorporibus contra cellulas B sive T
Similar endpoints
↥List of similar endpoints to
Common variable immunodeficiency with autoantibodies to B- or T-cells
based on the number of shared cases.
Similar with more cases:
- Common variable immunodeficiency
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 102 | 74 | 26 |
| Only index persons | 86 | 66 | 20 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 49.79 | 49.34 | 51.49 |
| Only index persons | 48.34 | 49.34 | 45.07 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8 | 6 | - |
| Unadjusted period prevalence (%) | 0.00 | 0.00 | - |
| Median age at first event (years) | 51.11 | 50.27 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3041096) Erythrocytes [Presence] in Urine by Automated
0
19
0.00
0.72
0.0
2.4
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
0
19
0.00
0.72
0.0
2.7
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
8
64
+∞
0.47
32.1
14.8
mg/l
11.3
22.3
—
8
50
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
0
15
0.00
0.47
0.0
1.2
—
7.3
—
0
8
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
0
11
0.00
0.23
0.0
1.5
—
—
—
0
0
(3002256) Pathology report gross observation
0
10
0.00
0.23
0.0
1.2
—
—
—
0
0
(3022145) Colonoscopy Study observation
0
10
0.00
0.23
0.0
1.2
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
8
74
+∞
0.00
22.8
12.3
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
8
74
+∞
0.00
31.2
16.7
umol/l
131.5
72.5
—
8
74
(40761536) Microorganisms panel - Urine sediment
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
70.8
—
0
5
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3000492) Spirometry study
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(4034850)
0
5
0.00
0.00
0.0
7.6
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3022621) pH of Urine by Test strip
0
8
0.00
0.00
0.0
3.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_CVID_BT_CELL_AB and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have D3_CVID_BT_CELL_AB.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: D3_CVID_BT_CELL_AB – Common variable immunodeficiency with autoantibodies to B- or T-cells
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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