cryoglobulinemia: Cryoglobulinemia is a type of vasculitis that is caused by abnormal proteins (antibodies) in the blood called 'cryoglobulins.' At cold temperatures, these proteins become solid or gel-like, which can block blood vessels and cause a variety of health problems. Many people affected by this condition will not experience any unusual signs or symptoms. When present, symptoms vary but may include breathing problems; fatigue; glomerulonephritis ; joint or muscle pain; purpura ; Raynaud's phenomenon ; skin death; and/or skin ulcers. In some cases, the exact underlying cause is unknown; however, cryoglobulinemia can be associated with a variety of conditions including certain types of infection; chronic inflammatory diseases (such as autoimmune disease ); and/or cancers of the blood or immune system . Treatment varies based on the severity of the condition, the symptoms present in each person and the underlying cause.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
56 |
4. Check minimum number of eventsNone |
56 |
5. Include endpointsNone |
56 |
6. Filter based on genotype QC (FinnGen only) |
56 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D89
- Name in latin
- Cryoglobulinaemia
Similar endpoints
↥List of similar endpoints to
Cryoglobulinemia
based on the number of shared cases.
Similar with more cases:
- Other disorders involving the immune mechanism, not elsewhere classified
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 308 | 146 | 161 |
| Only index persons | 253 | 121 | 132 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 58.79 | 59.34 | 58.14 |
| Only index persons | 56.02 | 55.87 | 56.15 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 56 | 25 | 31 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 55.57 | 50.01 | 60.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3004588) Protein electrophoresis panel - Serum or Plasma
23
22
17.04
22.45
4.7
1.4
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
16
11
19.96
18.37
3.2
1.4
g/l
0.2
0.3
0.47
16
11
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
16
12
18.27
17.54
3.1
1.4
g/l
1.2
1.2
0.09
16
12
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
13
10
16.63
13.85
1.4
1.4
—
—
—
0
0
(3015171) Extractable nuclear Ab [Units/volume] in Serum
13
10
16.63
13.85
1.6
1.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
43
146
9.38
13.85
10.3
3.0
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
48
186
12.01
13.81
28.6
10.7
mmol/l
1.2
1.2
0.24
40
154
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
14
13
14.03
13.40
4.6
1.3
—
—
—
0
0
(3018418) pH of Serum or Plasma
37
112
7.79
13.24
23.4
3.9
ph
7.4
7.4
0.09
12
24
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
13
12
13.81
12.43
4.5
1.0
g/l
9.1
9.3
0.04
13
12
(3037522) Nuclear Ab [Titer] in Serum
24
50
7.65
12.32
1.8
1.5
titre
304.0
323.6
—
5
11
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
12
11
13.61
11.45
2.7
1.8
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
15
7
28.49
11.41
6.8
1.4
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
20
38
7.63
11.06
9.8
3.1
%
0.8
1.2
0.28
12
15
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
12
12
12.45
10.83
1.4
1.2
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
40
150
6.83
10.82
11.7
5.9
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
19
35
7.70
10.79
9.9
3.3
%
0.0
0.2
1.08
11
14
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
14
18
10.04
10.65
8.4
4.6
mmol/l
23.0
25.6
1.48
14
18
(3012095) Magnesium [Moles/volume] in Serum or Plasma
27
72
6.31
10.62
3.5
5.2
mmol/l
0.8
0.8
0.67
27
66
(36304419) Bacteria [Presence] in Urine
33
106
6.15
10.56
8.5
2.9
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
19
36
7.47
10.49
8.8
2.9
%
0.6
0.4
—
10
9
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
11
10
13.44
10.49
3.2
1.5
—
—
—
0
0
(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis
11
10
13.44
10.49
4.9
1.0
g/l
37.9
37.0
—
11
10
(3012544) pH of Venous blood
19
37
7.26
10.20
14.2
3.7
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
13
16
10.28
10.17
1.4
1.3
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
26
70
6.07
10.04
9.8
2.0
umol/l
10.9
12.5
0.67
26
62
(3025159) Blasts/100 leukocytes in Blood
18
34
7.33
9.92
10.2
3.1
%
0.0
0.7
—
10
12
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
12
14
10.64
9.72
2.4
1.2
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
13
8
20.61
9.07
1.5
1.6
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
24
66
5.61
8.92
10.5
2.0
g/l
2.0
2.4
2.87
24
58
(3023368) Bacteria identified in Blood by Culture
32
114
5.22
8.72
12.9
5.5
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
13
9
18.30
8.71
1.5
1.6
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
24
68
5.43
8.58
3.3
1.7
—
—
—
0
0
(3000991) Gas panel - Venous blood
15
27
7.22
8.54
21.5
8.3
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
17
35
6.54
8.53
15.6
3.2
kpa
5.6
5.6
0.03
17
35
(3017143) Hepatitis C virus Ab [Presence] in Serum
22
58
5.60
8.52
3.3
1.7
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
26
81
5.13
8.27
2.7
1.5
g/l
2.3
2.6
0.24
21
46
(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis
12
9
16.52
7.81
5.0
1.0
g/l
0.0
0.0
—
12
9
(46235355) HIV 1 and 2 tests - Meaningful Use set
26
85
4.84
7.72
3.0
2.0
—
—
—
0
0
(4035726)
17
39
5.82
7.57
1.4
1.2
—
—
—
0
0
(3042733) HLA Ab [Presence] in Serum
7
0
+∞
7.44
4.3
0.0
—
—
—
0
0
(40768446) Kidney Pathology biopsy report
7
0
+∞
7.44
1.6
0.0
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
22
66
4.84
7.19
2.6
1.7
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
14
28
6.33
7.14
7.7
3.6
kpa
6.0
4.5
1.19
14
28
(3031040) Bacteria [#/volume] in Urine by Automated count
48
277
6.11
7.10
9.7
4.1
—
83.8
—
0
6
(3021879) Hepatitis B virus core Ab [Presence] in Serum
16
37
5.65
7.03
2.5
1.8
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
38
176
4.61
6.96
35.6
8.3
inr
1.2
1.2
0.03
13
52
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
11
18
7.36
6.71
3.0
1.4
—
—
—
0
0
(1616796) Gas panel - Central venous blood
10
7
16.98
6.68
5.2
4.6
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
21
64
4.65
6.68
3.3
2.4
s
30.1
29.5
0.23
21
64
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
12
22
6.67
6.61
4.4
2.4
%
1.1
1.2
0.20
12
22
(21494890) Protein electrophoresis panel - 24 hour Urine
9
5
20.99
6.50
2.1
1.2
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
21
68
4.34
6.12
2.7
2.6
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
46
261
5.27
6.09
22.7
11.8
e9/l
5.2
4.0
2.34
46
233
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
17
47
4.76
6.03
5.8
4.1
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
49
311
5.59
5.86
12.4
4.0
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
7
14.98
5.80
1.9
1.1
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
17
49
4.55
5.71
2.6
1.5
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
8
5
18.29
5.59
1.3
1.2
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
12
26
5.60
5.56
6.8
4.1
g/l
112.8
128.5
1.86
12
26
(3014111) Lactate [Moles/volume] in Serum or Plasma
12
26
5.60
5.56
10.8
8.0
mmol/l
1.3
1.5
0.12
12
26
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
9
8
13.09
5.51
5.6
1.0
g/l
0.0
0.0
—
9
8
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
9
8
13.09
5.51
5.6
1.0
g/l
0.0
0.0
—
9
8
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
17
51
4.35
5.40
2.6
1.5
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
14
36
4.85
5.36
1.9
1.7
—
—
—
0
0
(3024471) HLA-A [Type]
5
0
+∞
5.28
1.0
0.0
—
—
—
0
0
(3024932) HLA-DR beta [Type]
5
0
+∞
5.28
1.0
0.0
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
24
94
3.72
5.27
9.6
3.7
%
99.0
93.2
0.50
24
94
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
8
6
15.23
5.25
1.3
1.5
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
8
6
15.23
5.25
2.5
3.0
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
8
6
15.23
5.25
4.3
1.2
%
85.4
65.3
—
8
6
(3026008) Bacteria identified in Urine by Culture
27
117
3.53
5.05
3.8
2.8
—
—
—
0
0
(3002256) Pathology report gross observation
15
43
4.40
5.02
1.4
1.1
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
9
10
10.45
4.99
1.1
1.9
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
8
7
13.04
4.95
4.4
5.3
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
40
225
3.72
4.89
8.9
3.3
estimate
0.0
0.0
0.00
14
43
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
7
5
15.69
4.70
1.3
1.2
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
24
101
3.41
4.63
3.0
2.1
mg/l
3.2
3.3
0.09
24
95
(40768804) Tissue Pathology biopsy report
33
172
3.24
4.43
2.5
1.9
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
7
6
13.07
4.40
1.0
1.5
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
14
42
4.11
4.38
2.3
1.6
nmol/l
338.0
409.1
0.66
14
36
(3021601) Nitrite [Presence] in Urine by Test strip
39
226
3.39
4.34
11.8
4.5
estimate
0.0
0.0
0.00
14
42
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
36
199
3.27
4.34
6.0
5.2
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
39
227
3.37
4.29
9.1
3.4
estimate
0.0
0.0
0.00
14
40
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
23
99
3.25
4.22
3.5
3.1
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
28
136
3.12
4.18
3.6
3.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
19
73
3.43
4.17
1.6
1.3
iu/ml
81.1
44.6
0.51
11
22
(40768443) Skin Pathology biopsy report
9
15
6.92
4.00
2.2
1.2
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
16
57
3.53
3.92
2.2
1.5
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
6
5
13.19
3.85
1.7
1.0
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
6
5
13.19
3.85
1.0
1.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
13
42
3.73
3.64
1.5
1.9
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
6
6
10.99
3.58
1.8
1.5
pg
34.0
33.8
—
6
6
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
8
14
6.46
3.48
1.4
1.9
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
7
10
7.80
3.47
8.1
2.9
kpa
4.8
5.0
—
7
10
(3027315) Oxygen [Partial pressure] in Blood
7
10
7.80
3.47
8.1
2.9
kpa
8.0
7.6
—
7
10
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
9
19
5.43
3.40
2.0
1.7
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
8
15
6.02
3.32
1.4
1.8
%
98.6
83.9
—
8
15
(3003694) ABO and Rh group [Type] in Blood
24
120
2.75
3.25
1.6
1.4
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
8
16
5.64
3.18
2.5
2.5
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
6
8
8.22
3.13
1.5
1.3
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
5
10.79
3.03
1.2
1.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
21
101
2.73
3.03
16.3
3.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
22
109
2.68
2.99
14.1
8.6
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
7
13
5.98
2.97
1.4
1.8
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
25
133
2.59
2.94
9.2
3.5
estimate
0.0
0.0
0.00
14
38
(3030981) Hyaline casts [#/volume] in Urine by Automated count
9
24
4.26
2.81
4.3
3.1
e6/l
0.4
0.0
—
9
24
(3049717) Cytology report of Urine Cyto stain
8
19
4.73
2.80
1.9
2.9
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
11
38
3.36
2.76
9.5
3.6
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
14
57
2.94
2.70
1.4
1.3
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
7
15
5.17
2.69
1.4
1.8
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
26
147
2.43
2.64
6.6
3.4
mmol/l
2.3
2.3
0.82
26
125
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
5
7
7.69
2.60
10.8
3.4
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
5
7
7.69
2.60
1.6
1.4
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
8
21
4.26
2.57
12.3
12.5
%
90.7
91.9
—
8
21
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
6
12
5.45
2.47
1.5
1.7
—
—
—
0
0
(40761535) Cells panel - Urine sediment
9
30
3.37
2.27
9.9
3.7
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
5
9
5.97
2.26
1.4
1.1
—
—
—
0
0
(3013512) EKG study
22
128
2.18
1.99
4.7
4.4
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
17
3.82
1.89
1.3
1.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
29
193
2.04
1.82
9.1
3.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
18
100
2.18
1.80
9.8
3.2
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
5
13
4.11
1.75
1.4
1.2
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
6
19
3.41
1.71
8.3
4.8
%
60.2
55.4
—
6
19
(3000494) Fungus identified in Specimen by Culture
12
57
2.41
1.70
1.9
2.0
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
6
21
3.07
1.55
8.5
4.3
mmol/l
23.8
24.6
—
6
21
(3003327) Ova and parasites identified in Stool by Light microscopy
5
16
3.32
1.47
2.6
1.7
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
10
47
2.37
1.43
10.2
19.2
%
93.9
95.0
—
10
42
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
23
2.79
1.41
12.7
32.1
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
6
23
2.79
1.41
1.5
1.2
—
—
—
0
0
(3020891) Body temperature
5
17
3.12
1.39
5.0
5.5
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
13
73
2.02
1.23
4.5
3.7
mmol/l
2.5
2.5
0.21
13
62
(3041096) Erythrocytes [Presence] in Urine by Automated
21
141
1.78
1.18
8.4
2.9
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
8
40
2.16
1.17
1.5
1.6
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
23
159
1.76
1.17
3.0
1.9
pmol/l
97.3
97.0
0.00
12
84
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
35
274
1.74
1.14
4.7
3.0
—
—
—
0
0
(3022621) pH of Urine by Test strip
6
31
2.04
0.87
9.2
1.9
—
—
—
0
0
(3044889) 12 lead EKG panel
38
317
1.62
0.86
5.1
3.8
—
—
—
0
0
(3019060) Gas panel - Arterial blood
6
32
1.98
0.84
2.7
19.4
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
26
0.00
0.80
0.0
1.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
51
468
2.00
0.75
47.9
14.7
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
11
69
1.74
0.75
2.0
1.7
—
—
—
0
0
(4010399)
5
27
1.93
0.70
1.6
1.2
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
7
43
1.72
0.70
1.0
1.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
12
170
0.63
0.67
2.5
3.1
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
20
0.00
0.61
0.0
1.5
—
1.4
—
0
15
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
47
426
1.64
0.61
56.4
13.2
ml/min/173m2
59.5
82.3
4.58
47
344
(3019225) pH of Specimen
6
37
1.69
0.57
20.0
6.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
45
409
1.51
0.52
49.5
15.6
%
38.2
40.3
1.38
26
311
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
43
463
0.69
0.44
7.2
4.9
mmol/l
2.4
2.8
1.63
43
434
(4034850)
0
16
0.00
0.42
0.0
10.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
5
35
1.47
0.40
1.0
2.5
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
6
45
1.37
0.35
2.0
2.3
%
1.9
1.4
—
6
40
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
7
51
1.42
0.33
19.1
7.9
—
—
—
0
0
(3022145) Colonoscopy Study observation
7
54
1.34
0.32
1.1
1.3
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
41
380
1.29
0.30
69.6
18.1
%
14.1
13.6
1.34
41
373
(3008152) Bicarbonate [Moles/volume] in Arterial blood
5
38
1.35
0.24
4.4
21.2
mmol/l
22.9
24.7
—
5
33
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
5
41
1.24
0.22
1.0
2.6
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
12
106
1.17
0.11
1.6
1.9
pmol/l
433.0
482.1
0.29
12
92
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
14
148
0.93
0.03
4.1
4.6
%
29.1
20.9
—
8
72
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
32
314
1.04
0.00
5.0
3.1
u/l
61.3
48.4
0.39
32
294
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
18
181
0.99
0.00
4.1
5.2
ug/l
2.3
3.8
0.39
18
162
(3000492) Spirometry study
5
52
0.96
0.00
2.8
1.2
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
5
49
1.02
0.00
2.4
1.6
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
4.5
—
17.6
—
0
6
(3027008) Opiates [Presence] in Urine
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
0.8
—
0
5
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
11.8
—
617.3
—
0
6
(3023511) Choriogonadotropin [Units/volume] in Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
16.7
—
1054.0
—
0
6
(3027944) Amphetamines [Presence] in Urine
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_CRYOGLOBU and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have D3_CRYOGLOBU.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: D3_CRYOGLOBU – Cryoglobulinemia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data