This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
hereditary angioödema type 3
D3_ANGIOEDEMA_3
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
29 |
4. Check minimum number of eventsNone |
29 |
5. Include endpointsNone |
29 |
6. Filter based on genotype QC (FinnGen only) |
29 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
hereditary angioödema type 3
based on the number of shared cases.
Similar with more cases:
- Defects in the complement system
- Other immunodeficiencies
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 29 | 24 | 5 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | 44.39 | 42.58 | 53.06 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
10
14
10.38
7.18
4.4
3.1
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
18
56
6.84
6.18
11.2
4.1
inr
1.1
1.0
—
10
19
(3023368) Bacteria identified in Blood by Culture
15
45
5.83
5.18
5.2
2.7
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
17
64
5.00
4.36
8.1
4.0
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
19
86
4.51
3.69
3.5
7.0
mmol/l
1.2
1.2
0.47
14
77
(42870588) Differential panel, method unspecified - Blood
17
71
4.37
3.67
11.2
4.2
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
8
15
6.91
3.47
2.3
5.6
mmol/l
1.2
1.2
—
8
15
(3013826) Glucose [Moles/volume] in Serum or Plasma
22
121
4.37
3.20
5.1
3.8
mmol/l
6.2
6.7
0.69
22
107
(3018418) pH of Serum or Plasma
13
49
4.00
3.14
2.6
4.3
ph
7.4
7.4
—
6
10
(3020630) Protein [Mass/volume] in Serum or Plasma
6
9
8.04
3.02
2.5
1.7
g/l
71.3
68.7
—
6
9
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
16
72
3.73
2.97
3.5
2.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
5
6
9.71
2.86
2.8
1.8
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
5
7
8.31
2.65
3.8
5.7
mmol/l
25.1
25.3
—
5
7
(40768443) Skin Pathology biopsy report
5
7
8.31
2.65
1.6
1.1
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
5
7
8.31
2.65
1.6
1.7
%
96.6
109.0
—
5
7
(40768797) Stomach Pathology biopsy report
9
28
4.18
2.58
1.0
1.4
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
13
58
3.25
2.33
3.2
1.8
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
21
127
3.36
2.26
11.5
4.7
e9/l
0.5
0.6
0.80
21
117
(3006315) Basophils [#/volume] in Blood
21
128
3.31
2.26
11.5
4.7
e9/l
0.0
0.0
0.80
21
118
(3019198) Lymphocytes [#/volume] in Blood
21
131
3.17
2.22
11.5
4.7
e9/l
2.0
2.0
0.21
21
124
(3013115) Eosinophils [#/volume] in Blood
21
132
3.13
2.20
11.9
5.2
e9/l
0.2
0.2
0.87
21
124
(3013512) EKG study
11
47
3.16
2.08
2.0
3.7
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
6
16
4.43
2.05
1.8
1.2
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
30
3.28
1.90
2.0
1.4
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
6
18
3.92
1.85
2.0
1.2
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
6
18
3.92
1.85
6.2
2.7
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
12
58
2.82
1.81
3.0
2.3
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
19
117
2.81
1.81
12.0
4.8
%
0.6
0.7
0.30
19
109
(4010399)
5
13
4.41
1.79
2.2
1.2
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
22
150
2.92
1.75
13.4
9.8
e9/l
4.6
3.8
0.90
22
132
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
10
45
2.87
1.69
3.4
1.9
—
—
—
0
0
(3019225) pH of Specimen
5
14
4.08
1.69
1.8
8.4
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
17
102
2.61
1.66
7.9
3.7
—
—
—
0
0
(3002256) Pathology report gross observation
7
27
3.08
1.63
1.1
1.1
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
19
121
2.65
1.63
12.1
4.8
%
2.3
2.8
0.36
19
114
(3019069) Monocytes/100 leukocytes in Blood
19
122
2.62
1.59
12.3
5.0
%
7.2
8.0
0.81
19
116
(3007853) Bacteria identified in Skin by Aerobe culture
6
22
3.16
1.52
5.5
1.2
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
10
48
2.65
1.48
7.1
1.7
mg/l
3.5
3.0
—
10
42
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
37
0.00
1.47
0.0
1.7
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
19
125
2.51
1.47
12.2
4.8
%
28.8
30.0
0.20
19
120
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
13
77
2.25
1.21
3.3
2.8
u/l
24.3
26.9
0.32
13
69
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
5
20
2.80
1.20
2.8
4.3
u/l
238.4
230.2
—
5
20
(3018010) Neutrophils/100 leukocytes in Blood
18
123
2.22
1.18
11.6
4.7
%
58.4
56.6
0.30
18
118
(3033658) Prothrombin time (PT) actual/Normal
10
55
2.25
1.08
5.3
2.7
%
98.0
92.7
—
10
55
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
29
0.00
1.04
0.0
1.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
11
66
2.07
0.95
3.8
2.0
—
—
—
0
0
(3044889) 12 lead EKG panel
19
143
1.95
0.85
3.9
2.5
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
6
33
2.03
0.84
1.8
2.1
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
0
25
0.00
0.83
0.0
3.6
—
15.2
—
0
8
(3003338) MCHC [Mass/volume]
19
229
0.51
0.81
36.9
12.2
g/l
330.5
332.8
0.27
19
229
(3029937) Albumin [Presence] in Urine by Test strip
10
62
1.94
0.77
4.9
3.0
estimate
0.0
0.0
—
5
24
(3022145) Colonoscopy Study observation
5
25
2.20
0.77
1.2
1.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
11
71
1.88
0.76
4.5
2.4
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
16
118
1.79
0.72
5.5
3.9
estimate
0.0
0.0
—
5
24
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
5
27
2.02
0.72
1.6
1.7
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
5
28
1.94
0.69
2.0
2.1
nmol/l
2165.2
1169.9
—
5
21
(3035350) Ketones [Presence] in Urine by Test strip
16
119
1.77
0.69
4.3
2.7
estimate
0.0
0.0
—
5
23
(3009261) Glucose [Presence] in Urine by Test strip
16
120
1.74
0.66
4.3
2.9
estimate
0.0
0.0
—
5
23
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
13
92
1.75
0.66
4.8
2.8
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
6
34
1.96
0.63
1.5
1.9
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
29
267
+∞
0.61
27.6
9.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
7
45
1.73
0.54
3.3
2.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
20
169
1.59
0.49
11.8
3.7
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
11
80
1.60
0.47
2.9
2.0
pmol/l
99.1
94.3
—
6
45
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
9
64
1.59
0.45
1.4
1.6
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
11
81
1.58
0.45
1.7
1.6
—
—
—
0
0
(40758558) Short blood count panel - Blood
9
69
1.44
0.43
8.4
6.1
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
0
17
0.00
0.42
0.0
2.0
—
0.4
—
0
11
(3017143) Hepatitis C virus Ab [Presence] in Serum
5
35
1.52
0.41
1.6
1.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
5
35
1.52
0.41
4.8
1.4
—
—
—
0
0
(3015736) pH of Urine
12
92
1.52
0.40
4.2
2.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
7
50
1.53
0.35
3.4
2.4
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
7
53
1.42
0.34
2.7
2.8
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
7
53
1.42
0.34
1.4
1.6
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
11
0.00
0.22
0.0
1.1
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
0
13
0.00
0.21
0.0
3.2
—
—
—
0
0
(3022621) pH of Urine by Test strip
0
14
0.00
0.20
0.0
2.6
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
7
57
1.30
0.20
2.9
2.7
umol/l
311.0
302.3
—
7
52
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
22
232
0.79
0.20
3.7
3.2
mmol/l
1.6
1.2
0.99
17
217
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
21
222
0.80
0.19
5.3
3.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
8
68
1.24
0.19
1.8
2.1
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
7
83
0.79
0.17
1.9
1.8
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
12
105
1.24
0.14
3.0
1.8
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
10
101
0.98
0.00
2.8
2.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
7
76
0.90
0.00
1.3
1.3
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
2.3
—
0
6
(3008037) Lactate [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
3.4
—
1.7
—
0
5
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
3.4
—
9.0
—
0
5
(3010813) Leukocytes [#/volume] in Blood
29
281
+∞
0.00
40.5
15.3
e9/l
7.5
6.6
1.52
29
276
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005082) Progesterone [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
33.3
—
0
5
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
4.5
—
40.1
—
0
6
(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
1.2
—
0
5
(3026361) Erythrocytes [#/volume] in Blood
29
281
+∞
0.00
40.3
15.2
e12/l
4.5
4.5
0.19
29
276
(3014051) Protein [Presence] in Urine by Test strip
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
8
0.00
-0.00
0.0
3.6
—
19.1
—
0
8
(3025130) Human papilloma virus identified in Specimen
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: D3_ANGIOEDEMA_3 – hereditary angioödema type 3
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).