This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Hereditary angioödema type 1
D3_ANGIOEDEMA_1
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
36 |
4. Check minimum number of eventsNone |
36 |
5. Include endpointsNone |
36 |
6. Filter based on genotype QC (FinnGen only) |
36 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Hereditary angioödema type 1
based on the number of shared cases.
Similar with more cases:
- Defects in the complement system
- Other immunodeficiencies
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 36 | 27 | 9 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | 55.51 | 54.69 | 57.98 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
20
10
43.75
27.80
2.9
1.3
g/l
1.2
1.2
—
20
10
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
20
10
43.75
27.80
2.9
1.3
g/l
0.1
0.3
—
13
10
(42870588) Differential panel, method unspecified - Blood
26
83
8.68
8.98
13.1
4.1
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
10
12
11.15
7.98
6.8
4.4
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
10
6
22.25
7.22
6.9
1.3
%
160.2
177.5
—
10
6
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
11
20
7.48
6.24
2.1
1.4
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
28
129
6.24
5.87
15.5
4.8
%
0.7
0.7
0.13
28
122
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
9
8
14.44
5.65
7.2
1.1
%
100.7
110.8
—
9
8
(3013650) Neutrophils [#/volume] in Blood by Automated count
31
168
7.06
5.28
19.3
8.7
e9/l
3.5
4.0
0.70
31
153
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
10
20
6.54
5.11
1.8
1.3
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
7
5
16.85
4.78
1.0
1.0
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
9
13
8.80
4.48
10.4
1.4
g/l
6.7
1.2
—
9
13
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
11
28
5.22
4.35
8.1
3.2
u/l
200.1
223.6
0.85
11
28
(3015736) pH of Urine
24
116
4.21
4.09
4.3
3.4
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
6
5
13.99
3.91
2.0
1.0
mg/l
11.5
9.7
—
6
5
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
11
31
4.67
3.83
2.1
1.4
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
6
6
11.64
3.64
1.0
1.3
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
7
10
8.36
3.54
8.3
1.0
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
18
78
3.62
3.46
1.2
1.2
u/ml
0.5
0.6
—
8
21
(40760892) CBC W Ordered Manual Differential panel - Blood
18
79
3.56
3.38
6.6
5.2
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
7
11
7.58
3.36
60.4
2.8
g/l
129.4
123.2
—
7
11
(3042936) Bacteria identified in Isolate by Culture
11
35
4.09
3.25
3.2
2.1
—
—
—
0
0
(40758558) Short blood count panel - Blood
17
74
3.46
3.20
12.4
6.1
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
5
5
11.30
3.07
1.6
1.6
%
55.4
59.4
—
5
5
(3030905) Polymorphonuclear cells [#/volume] in Blood
5
5
11.30
3.07
1.6
1.6
e9/l
3.8
5.4
—
5
5
(3009445) Proteinase 3 Ab [Units/volume] in Serum
6
9
7.72
2.99
1.3
1.2
—
—
—
0
0
(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis
6
9
7.72
2.99
9.3
1.0
g/l
8.1
1.2
—
6
9
(3000991) Gas panel - Venous blood
7
14
5.92
2.88
62.1
2.6
—
—
—
0
0
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
5
6
9.40
2.84
1.8
1.7
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
15
66
3.18
2.70
2.3
1.2
g/l
1.6
2.3
—
10
41
(3016502) Oxygen saturation in Arterial blood
8
21
4.58
2.64
4.3
4.2
%
96.5
95.3
—
8
21
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
6
13
5.30
2.38
1.8
2.7
%
0.6
0.7
—
6
13
(3003396) Base excess in Arterial blood by calculation
8
25
3.81
2.25
5.0
3.8
mmol/l
2.0
1.2
—
8
15
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
14
4.91
2.25
70.3
2.4
%
1.2
2.0
—
6
14
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
6
14
4.91
2.25
1.8
2.6
%
1.7
2.0
—
6
14
(3012544) pH of Venous blood
7
20
4.08
2.18
60.6
2.3
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
5
10
5.60
2.14
1.6
3.0
mmol/l
24.0
23.5
—
5
10
(3000492) Spirometry study
6
16
4.27
2.03
2.0
1.6
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
15
77
2.63
1.96
7.5
2.8
%
99.0
93.8
0.48
15
77
(3023368) Bacteria identified in Blood by Culture
12
55
2.77
1.93
8.3
3.5
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
28
203
2.70
1.88
10.3
3.9
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
17
95
2.50
1.85
6.6
6.8
inr
1.2
1.1
—
6
29
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
16
87
2.51
1.84
7.1
2.7
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
7
24
3.36
1.83
5.6
3.7
kpa
13.3
14.2
—
7
24
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
7
24
3.36
1.83
5.6
3.7
kpa
5.2
4.9
—
7
24
(3041096) Erythrocytes [Presence] in Urine by Automated
16
88
2.47
1.79
3.3
3.2
—
—
—
0
0
(3019060) Gas panel - Arterial blood
5
13
4.28
1.77
5.4
5.2
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
6
19
3.57
1.74
70.5
2.4
mmol/l
-0.5
2.1
—
6
12
(40761535) Cells panel - Urine sediment
6
19
3.57
1.74
2.8
2.7
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
13
66
2.52
1.70
1.8
1.6
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
5
14
3.96
1.67
2.0
3.0
%
93.9
92.2
—
5
14
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
5
14
3.96
1.67
1.0
1.4
u/l
38.0
42.7
—
5
14
(3007853) Bacteria identified in Skin by Aerobe culture
8
33
2.82
1.65
4.8
1.3
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
6
21
3.21
1.58
3.7
4.7
—
—
—
0
0
(4010399)
6
21
3.21
1.58
1.7
1.4
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
7
28
2.85
1.54
2.1
1.5
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
13
69
2.38
1.53
4.8
3.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
12
63
2.36
1.43
3.2
1.9
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
5
17
3.24
1.41
46.0
2.1
mmol/l
26.4
24.5
—
5
17
(3002256) Pathology report gross observation
8
38
2.41
1.28
1.3
1.1
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
6
26
2.56
1.24
34.7
11.2
—
1.3
—
0
5
(3000850) Epithelial cells [#/volume] in Urine
11
60
2.20
1.19
6.3
2.1
e6/l
2.4
5.0
1.32
11
53
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
18
122
1.95
1.09
5.6
3.5
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
5
22
2.47
1.07
4.8
2.8
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
5
22
2.47
1.07
2.0
1.7
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
12
71
2.04
1.05
8.0
2.5
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
6
28
2.36
0.97
2.3
1.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
30
2.19
0.92
1.0
1.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
20
148
1.79
0.87
6.5
3.8
—
—
—
0
0
(3026782) Osmolality of Urine
9
52
1.97
0.85
7.1
2.4
mosm/kgh2o
438.6
514.1
—
9
44
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
6
33
1.98
0.83
2.8
2.2
%
14.1
25.1
—
6
26
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
7
41
1.87
0.75
1.3
1.5
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
13
89
1.72
0.71
1.5
1.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
12
82
1.70
0.65
3.4
2.7
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
8
54
1.62
0.62
1.1
1.2
—
4.5
—
0
23
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
20
0.00
0.62
0.0
1.4
—
2.9
—
0
11
(3004789) Transferrin [Mass/volume] in Serum or Plasma
6
36
1.80
0.60
3.0
2.1
g/l
2.5
2.5
—
6
31
(3044889) 12 lead EKG panel
25
209
1.64
0.60
4.9
3.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
13
93
1.62
0.59
4.1
1.9
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
27
232
1.65
0.57
3.7
3.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
9
127
0.61
0.57
2.4
2.7
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
16
0.00
0.42
0.0
1.7
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
17
0.00
0.42
0.0
1.5
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
9
70
1.38
0.41
2.8
2.1
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
6
41
1.55
0.38
1.2
1.1
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
36
349
+∞
0.22
41.6
15.9
e9/l
280.6
255.0
1.31
36
339
(3024731) MCV [Entitic volume]
36
350
+∞
0.22
41.5
15.8
fl
90.4
90.6
0.14
36
345
(3026361) Erythrocytes [#/volume] in Blood
36
350
+∞
0.22
41.6
15.9
e12/l
4.6
4.5
0.55
36
341
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
0
10
0.00
0.22
0.0
3.7
—
25.0
—
0
10
(3000963) Hemoglobin [Mass/volume] in Blood
36
350
+∞
0.22
41.9
16.0
g/l
136.1
136.5
0.09
36
345
(3035941) MCH [Entitic mass]
36
350
+∞
0.22
41.6
15.8
pg
30.0
30.2
0.31
36
345
(3010813) Leukocytes [#/volume] in Blood
36
350
+∞
0.22
41.8
15.9
e9/l
7.3
6.6
0.85
36
341
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
0
10
0.00
0.22
0.0
2.3
—
1.5
—
0
10
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
48
1.30
0.22
3.0
2.4
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
30
284
1.34
0.18
42.8
10.5
%
39.0
40.3
0.28
22
218
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
14
123
1.23
0.15
1.9
1.6
pmol/l
97.0
108.8
—
9
57
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
5
44
1.16
0.10
3.2
2.3
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
6
56
1.09
0.09
2.8
1.6
pmol/l
413.5
582.1
—
6
49
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
6
71
0.81
0.08
2.0
1.5
—
—
—
0
0
(3013512) EKG study
6
73
0.79
0.08
3.0
3.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
12
127
0.92
0.02
2.3
1.8
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
15
147
1.03
0.00
3.8
2.5
ug/l
91.5
80.1
0.14
15
141
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
5
0.00
0.00
0.0
7.0
—
198.0
—
0
5
(3004616) Nuclear Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
8
82
0.97
0.00
2.9
2.6
mmol/l
6.3
7.4
—
8
71
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003181) Sodium [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.0
—
55.6
—
0
5
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
52.9
—
0
9
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
0
9
0.00
0.00
0.0
4.0
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
0.9
—
0
6
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
6
0.00
0.00
0.0
1.0
—
31.8
—
0
6
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
6
62
0.96
0.00
2.7
1.6
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: D3_ANGIOEDEMA_1 – Hereditary angioödema type 1
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).