Acquired pure red cell aplasia [erythroblastopenia]

D3_ACQPUREREDCLLAPLASIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D60
  • Hospital discharge: ICD-9 2848C
  • Hospital discharge: ICD-8 28404
  • Cause of death: ICD-10 D60
  • Cause of death: ICD-9 2848C
  • Cause of death: ICD-8 28404

2 out of 7 registries used, show all original rules.

158

4. Check minimum number of events

None

158

5. Include endpoints

None

158

6. Filter based on genotype QC (FinnGen only)

158

Control definitions (FinnGen only)

Control exclude
D3_APLASTICANDOTHANAEMIA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D60-D64
Name in latin
Erythroblastopenia [pura] acquisita

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1585 812 763
Only index persons 1228 642 586
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 50.27 49.87 50.40
Only index persons 51.23 50.58 51.94

-FinnGen-

Key figures

All Female Male
Number of individuals 158 78 80
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 61.35 56.48 66.11

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
146
Matched controls
1458
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D60.9
ICD-10 Finland
Acquired pure red cell aplasia, unspecified
+∞
97.0
82
*
D64.9
ICD-10 Finland
Anaemia, unspecified
53.1
54.1
64
21
D60.0
ICD-10 Finland
Chronic acquired pure red cell aplasia
+∞
28.0
26
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.8
21.2
79
245
D60.1
ICD-10 Finland
Transient acquired pure red cell aplasia
+∞
20.3
19
*
122
Kela drug reimbursment
Aplastic anaemia
+∞
17.0
16
*
XW000
NOMESCO Finland
Bone marrow biopsy
14.1
15.3
26
22
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
10.9
14.5
28
31
D60.8
ICD-10 Finland
Other acquired pure red cell aplasias
+∞
13.8
13
*
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
+∞
12.7
12
*
WW500
NOMESCO Finland
Blood transfusion
13.4
12.3
21
18
UJF32
NOMESCO Finland
Coloscopy
3.8
11.4
58
214
UJF92
NOMESCO Finland
Capsular endoscopy
32.4
9.6
12
*
28404
ICD-8 Finland
Aplastic anaemia, Erythroblastopenia acquisita
+∞
8.4
8
*
L04AD01
ATC
ciclosporin; systemic
12.8
8.3
14
12
J01MA12
ATC
levofloxacin; systemic
3.3
7.6
42
159
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.8
7.5
63
315
D64.8
ICD-10 Finland
Other specified anaemias
31.7
7.2
9
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.1
6.9
27
77
A28
ICPC
Limited function/disability NOS
3.4
6.6
35
125
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
6.5
78
460
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
6.4
34
123
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
28.0
6.3
8
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
+∞
6.3
6
*
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
+∞
6.3
6
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
8.3
6.3
13
17
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
5.7
6.2
17
33
B82
ICPC
Anaemia other/unspecified
13.3
6.2
10
8
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.9
6.1
19
43
R50.9
ICD-10 Finland
Fever, unspecified
3.4
6.0
29
99

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
53
43
18.04
56.81
2.8
2.0
g/l
1.3
1.6
0.86
44
38
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
32
29
13.58
31.24
1.7
1.8
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
22
11
23.07
28.93
1.3
1.3
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
59
144
5.94
24.62
4.0
2.4
%
30.1
22.5
1.24
52
122
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
82
279
5.03
22.87
3.3
2.0
mg/l
3.2
2.9
0.41
73
231
(3023520) Reticulocytes [#/volume] in Blood
48
104
6.19
22.59
13.8
2.9
e9/l
63.8
63.7
0.01
41
81
(21494434) Karyotype in Bone marrow
17
10
18.93
20.58
1.2
1.0
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
99
478
3.87
15.47
5.3
2.5
ug/l
325.8
104.9
2.29
94
427
(42870588) Differential panel, method unspecified - Blood
86
386
3.69
14.87
13.2
5.4
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
17
18
10.46
14.59
1.9
1.4
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
18
24
8.34
12.98
1.7
3.0
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
100
532
3.40
12.52
14.4
5.6
%
0.7
0.6
0.92
95
487
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
16
20
8.79
12.10
1.3
1.8
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
101
548
3.34
12.09
14.4
5.5
%
2.7
2.7
0.15
96
503
(3019069) Monocytes/100 leukocytes in Blood
101
550
3.32
11.98
14.7
6.0
%
9.2
8.6
0.98
96
506
(3028026) IgM [Mass/volume] in Serum or Plasma
28
65
5.02
11.78
1.9
1.7
g/l
1.0
1.2
0.30
22
59
(3013115) Eosinophils [#/volume] in Blood
107
607
3.36
11.76
13.0
5.7
e9/l
0.2
0.2
0.04
97
532
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
15
18
9.10
11.69
1.3
1.5
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
104
582
3.30
11.66
12.5
5.5
e9/l
0.6
0.6
0.18
93
502
(3006315) Basophils [#/volume] in Blood
104
583
3.29
11.61
12.5
5.5
e9/l
0.0
0.0
0.14
93
506
(3003458) Phosphate [Moles/volume] in Serum or Plasma
45
152
3.74
11.59
11.0
6.3
mmol/l
1.1
1.1
0.12
40
137
(3002030) Lymphocytes/100 leukocytes in Blood
102
568
3.25
11.46
14.7
5.8
%
29.5
27.7
0.60
96
520
(40768797) Stomach Pathology biopsy report
46
161
3.62
11.20
1.4
1.2
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
12
11
11.72
11.19
1.2
1.2
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
19
32
6.61
11.14
1.3
1.7
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
30
78
4.51
10.99
2.3
2.4
—
—
—
0
0
(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum
15
20
8.18
10.75
1.3
1.8
u/ml
236.6
363.7
—
7
11
(3012095) Magnesium [Moles/volume] in Serum or Plasma
47
171
3.49
10.75
5.4
4.6
mmol/l
0.8
0.8
1.57
42
155
(3019309) Folate [Moles/volume] in Red Blood Cells
55
223
3.25
10.54
2.3
1.7
nmol/l
1101.8
1186.1
0.27
38
165
(3019198) Lymphocytes [#/volume] in Blood
103
596
3.09
10.47
13.2
5.7
e9/l
1.7
1.9
0.58
94
536
(3023368) Bacteria identified in Blood by Culture
71
336
3.02
10.39
7.9
3.7
—
—
—
0
0
(3034860) Kappa light chains.free [Mass/volume] in Serum
20
39
5.73
10.13
2.1
2.6
mg/l
39.4
77.0
0.55
15
31
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
20
39
5.73
10.13
2.1
2.6
mg/l
36.4
35.2
0.03
15
31
(3018010) Neutrophils/100 leukocytes in Blood
97
557
2.92
9.75
13.6
5.6
%
55.9
57.5
0.56
92
514
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
13
17
8.24
9.42
1.4
1.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
73
370
2.81
9.17
6.1
2.4
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
12
5
25.77
9.05
1.4
1.4
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
94
545
2.79
9.05
11.3
3.8
—
—
—
0
0
(3000991) Gas panel - Venous blood
30
90
3.88
9.02
12.1
7.7
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
46
183
3.14
8.94
1.7
1.6
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
35
119
3.49
8.76
8.7
6.0
mmol/l
-0.2
1.1
0.76
27
100
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
10
10
10.61
8.73
1.1
1.3
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
10
10
10.61
8.73
2.2
2.7
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
38
137
3.34
8.67
1.8
1.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
48
199
3.03
8.66
2.4
1.7
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
98
591
2.73
8.56
13.2
6.6
mmol/l
1.2
1.2
0.93
85
498
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
83
461
2.69
8.56
3.5
1.9
pmol/l
92.8
96.3
0.36
52
226
(3013650) Neutrophils [#/volume] in Blood by Automated count
108
694
2.76
8.15
18.9
8.3
e9/l
3.9
4.1
0.32
98
598
(3024561) Albumin [Mass/volume] in Serum or Plasma
85
487
2.61
8.10
9.4
4.5
g/l
33.7
35.7
2.47
77
449
(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
11
14
8.37
8.09
4.7
4.6
u/ml
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
61
302
2.66
7.78
5.3
2.9
umol/l
360.3
8620.6
1.76
52
248
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
25
73
3.88
7.77
7.2
7.9
mmol/l
23.8
24.2
0.19
25
73
(3011412) CD3 cells [#/volume] in Blood
10
12
8.83
7.66
2.4
2.0
e9/l
0.6
1.0
—
5
5
(3018418) pH of Serum or Plasma
69
370
2.54
7.40
9.3
3.6
ph
7.4
7.4
0.56
15
73
(3007853) Bacteria identified in Skin by Aerobe culture
35
132
3.12
7.35
1.9
1.6
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
10
5
21.20
7.23
1.4
1.4
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
26
82
3.60
7.23
1.3
1.4
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
57
284
2.58
7.07
2.2
1.5
nmol/l
22.7
20.0
0.60
51
227
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
20
53
4.18
7.06
11.7
8.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
60
309
2.52
6.93
10.2
6.6
—
—
—
0
0
(3012544) pH of Venous blood
30
107
3.23
6.88
5.6
4.9
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
56
282
2.53
6.75
4.8
2.3
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
47
218
2.65
6.70
2.0
1.8
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
18
46
4.29
6.64
2.6
2.0
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
35
143
2.86
6.33
5.6
2.9
umol/l
8.6
7.2
0.19
30
124
(3015822) Parvovirus B19 DNA [Presence] in Serum by NAA with probe detection
6
0
+∞
6.29
1.8
0.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
21
63
3.69
6.25
1.7
1.7
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
98
650
2.34
6.18
13.2
5.3
umol/l
13.2
11.3
0.58
93
612
(3030905) Polymorphonuclear cells [#/volume] in Blood
12
23
5.56
6.11
4.7
2.5
e9/l
3.7
3.9
0.14
12
23
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
12
23
5.56
6.11
5.7
2.6
%
55.6
58.5
0.21
12
23
(3037756) Immunofixation for Serum or Plasma
12
23
5.56
6.11
1.4
1.4
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
28
103
3.09
6.08
5.9
4.8
mmol/l
1.8
1.8
0.00
22
72
(3021440) Promyelocytes/100 leukocytes in Blood
26
93
3.15
5.91
12.5
3.7
%
0.1
0.2
0.50
16
26
(3042936) Bacteria identified in Isolate by Culture
38
170
2.63
5.75
2.7
1.9
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
25
89
3.15
5.72
11.6
3.8
%
0.0
0.4
0.56
14
22
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
10
17
6.21
5.70
14.7
2.2
pg
33.9
32.0
—
10
17
(3017181) Myelocytes/100 leukocytes in Blood
27
102
2.99
5.59
12.4
3.6
%
0.5
0.9
0.80
16
32
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
32
136
2.70
5.34
2.2
1.7
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
23
82
3.11
5.24
1.8
1.4
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
24
88
3.04
5.22
12.9
3.6
%
0.2
0.5
0.58
13
18
(3002256) Pathology report gross observation
33
147
2.57
5.00
1.5
1.3
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
31
134
2.63
4.99
2.3
1.8
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
44
227
2.30
4.84
5.4
3.4
ng/l
76.3
207.7
1.04
37
176
(3010503) CD19 cells [#/volume] in Blood
8
7
11.95
4.84
2.8
1.4
e9/l
0.1
0.1
—
8
7
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
14
38
3.95
4.76
3.4
2.3
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
82
545
2.05
4.68
23.5
9.0
e9/l
0.0
0.0
0.00
66
442
(36304419) Bacteria [Presence] in Urine
58
344
2.08
4.47
4.3
3.1
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
62
377
2.06
4.47
3.7
2.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
47
257
2.18
4.47
1.9
1.3
g/l
2.0
2.3
0.52
30
147
(3032080) INR in Blood by Coagulation assay
75
492
2.00
4.36
10.6
9.4
inr
1.2
1.3
0.74
26
151
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
7
6
12.12
4.31
1.1
1.0
—
—
—
0
0
(3026782) Osmolality of Urine
45
245
2.17
4.31
3.0
2.9
mosm/kgh2o
508.6
544.6
0.57
35
207
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
22
87
2.78
4.18
4.5
7.5
mmol/l
2.8
1.5
0.78
16
66
(3029634) Reagin Ab [Titer] in Serum by VDRL
8
10
8.35
4.11
1.7
1.8
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
7
7
10.39
4.05
1.0
2.7
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
7
7
10.39
4.05
1.0
2.7
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
10
24
4.38
3.95
1.5
1.5
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
10
24
4.38
3.95
1.5
1.5
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
59
366
1.98
3.94
4.7
2.9
u/l
37.8
32.7
0.44
52
346
(3000850) Epithelial cells [#/volume] in Urine
47
270
2.05
3.88
3.3
2.5
e6/l
2.6
5.0
2.42
40
238
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
22
91
2.65
3.84
2.7
3.3
ng/l
272.5
176.3
0.33
22
79
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
45
257
2.05
3.76
2.7
1.7
mg/l
0.8
1.4
1.48
34
189
(3027315) Oxygen [Partial pressure] in Blood
10
25
4.20
3.76
6.6
2.3
kpa
9.4
8.6
—
10
25
(3013290) Carbon dioxide [Partial pressure] in Blood
10
25
4.20
3.76
6.6
2.3
kpa
4.8
5.1
—
10
25
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
8
12
6.95
3.72
1.5
1.7
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
8
12
6.95
3.72
1.1
1.0
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
111
865
1.95
3.60
4.5
3.7
pmol/l
15.0
14.9
0.12
105
757
(3014576) Chloride [Moles/volume] in Serum or Plasma
29
142
2.28
3.55
11.4
6.5
mmol/l
104.6
104.2
0.12
29
137
(3016650) Hepatitis A virus Ab [Presence] in Serum
8
13
6.42
3.54
1.0
1.0
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
68
456
1.86
3.52
4.7
3.3
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
19
77
2.67
3.45
1.8
1.4
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
56
355
1.89
3.43
4.1
3.2
mmol/l
6.8
7.6
0.74
49
291
(3037522) Nuclear Ab [Titer] in Serum
28
137
2.27
3.43
1.4
1.4
titre
173.3
685.9
—
6
34
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
10
27
3.89
3.41
2.0
1.4
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
14
48
3.10
3.39
2.5
1.6
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
53
334
1.88
3.29
4.3
3.2
mg/l
89.9
258.2
0.40
35
210
(3000012) Reticulocyte production index
6
7
8.85
3.29
3.0
2.7
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
6
7
8.85
3.29
1.8
2.6
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
7
11
6.60
3.22
1.4
4.1
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
13
44
3.13
3.22
2.4
1.5
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
13
45
3.06
3.10
1.2
1.0
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
59
392
1.81
3.06
4.7
3.3
e6/l
18.9
58.6
1.85
49
306
(3018095) Leukocytes [#/volume] in Urine
66
454
1.78
3.05
5.4
3.9
e6/l
89.3
69.8
0.15
53
324
(3010421) pH of Blood
10
30
3.49
2.96
7.1
2.2
ph
7.4
7.4
—
10
25
(4062490)
6
9
6.87
2.89
1.2
1.0
—
—
—
0
0
(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma
6
9
6.87
2.89
2.2
1.9
mg/l
9.8
3.6
—
6
9
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
57
381
1.78
2.87
4.6
3.2
ng/l
2199.6
1304.8
1.09
50
316
(3037467) Urinalysis macro (dipstick) panel - Urine
107
855
1.78
2.86
6.3
4.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
68
479
1.74
2.85
2.5
2.2
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
5
6
8.55
2.77
2.2
1.3
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
65
457
1.72
2.72
6.5
3.8
ng/l
73.5
34.9
0.80
51
331
(3024928) Oxygen saturation in Venous blood
8
19
4.38
2.71
1.9
2.5
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
10
32
3.27
2.69
1.2
1.3
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
53
355
1.74
2.62
4.6
3.2
e6/l
0.1
0.3
2.27
44
267
(3035637) Corticotropin [Mass/volume] in Plasma
6
11
5.62
2.56
1.3
1.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
22
110
2.16
2.56
1.8
1.7
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
34
201
1.88
2.51
3.9
3.3
e6/l
0.8
2.1
0.99
20
112
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
6
12
5.15
2.42
2.3
1.8
—
—
—
0
0
(4035726)
22
113
2.10
2.40
1.8
1.4
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
43
278
1.75
2.38
1.4
1.2
u/ml
2.8
1.1
0.37
12
68
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
10
35
2.98
2.35
1.0
1.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
30
175
1.88
2.31
1.3
1.3
iu/ml
29.2
24.7
—
10
56
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
6
13
4.75
2.29
1.0
1.1
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
51
350
1.68
2.27
5.7
4.1
mg/mmol
15.7
60.9
0.41
37
215
(3022313) Gas panel - Capillary blood
15
67
2.37
2.25
4.9
6.8
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
10
36
2.90
2.24
3.7
3.4
—
—
—
0
0
(3044889) 12 lead EKG panel
98
794
1.62
2.21
5.2
3.9
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
8
24
3.45
2.21
2.3
1.6
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
7
19
3.80
2.17
2.4
1.5
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
7
19
3.80
2.17
3.1
1.5
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
6
14
4.41
2.17
2.3
1.7
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
125
1080
1.75
2.17
5.6
4.5
mu/l
2.1
2.0
0.31
118
960
(3000764) Benzodiazepines [Presence] in Urine
11
43
2.67
2.14
1.5
1.2
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
94
758
1.59
2.13
5.2
2.8
u/l
82.5
49.0
1.15
88
700
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
9
31
3.02
2.11
3.1
1.6
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
9
31
3.02
2.11
3.1
1.7
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
20
3.61
2.08
2.3
1.7
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
14
63
2.34
2.08
4.7
6.9
mmol/l
25.0
24.5
0.19
14
63
(3027944) Amphetamines [Presence] in Urine
11
44
2.61
2.06
1.5
1.2
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
11
44
2.61
2.06
1.5
1.2
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
11
44
2.61
2.06
1.5
1.2
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
6
15
4.11
2.06
2.7
1.5
—
—
—
0
0
(3019060) Gas panel - Arterial blood
15
70
2.26
2.06
4.9
3.5
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
46
317
1.64
1.99
1.6
1.5
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
7
21
3.44
1.99
1.9
1.6
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
135
1203
1.84
1.97
37.1
13.5
mg/l
23.1
23.7
0.08
122
945
(3015377) Calcium [Moles/volume] in Serum or Plasma
56
406
1.59
1.97
4.6
3.1
mmol/l
2.4
2.4
0.12
48
344
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
13
58
2.35
1.97
2.5
2.3
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
8
27
3.06
1.96
1.9
1.3
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
5
11
4.65
1.95
1.4
1.4
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
34
217
1.72
1.95
3.7
2.8
e6/l
0.6
1.0
0.57
20
126
(3009542) Hematocrit [Volume Fraction] of Blood
123
1071
1.67
1.92
33.7
14.5
%
36.8
39.8
4.05
89
746
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
22
123
1.92
1.92
6.5
2.9
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
37
244
1.67
1.88
13.1
5.1
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
10
40
2.60
1.87
1.5
1.3
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
6
17
3.62
1.85
12.7
2.2
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
6
17
3.62
1.85
9.0
3.5
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
5
12
4.26
1.83
1.4
1.2
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
9
35
2.66
1.83
1.3
1.2
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
28
172
1.76
1.83
1.3
1.3
u/ml
50.0
14.1
—
6
75
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
6
18
3.42
1.76
1.0
1.7
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
7
24
3.00
1.74
1.0
1.1
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
5
13
3.93
1.73
3.0
1.8
%
60.9
57.7
—
5
13
(3021788) Differential panel - Synovial fluid
5
13
3.93
1.73
2.0
1.7
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
5
13
3.93
1.73
1.6
1.2
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
5
13
3.93
1.73
2.4
1.6
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
7
25
2.88
1.67
3.7
1.5
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
5
14
3.65
1.63
1.4
2.1
—
—
—
0
0
(1616796) Gas panel - Central venous blood
7
26
2.77
1.60
5.3
3.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
137
1246
1.75
1.59
31.8
12.4
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
7
27
2.66
1.53
1.4
1.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
88
733
1.45
1.50
3.1
3.0
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
9
38
2.45
1.48
1.9
1.1
g/l
0.3
0.2
—
9
38
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
5
16
3.19
1.45
3.0
3.3
nmol/l
6.7
3.1
—
5
16
(44806118)
5
16
3.19
1.45
2.8
2.0
—
—
—
0
0
(44790049)
5
16
3.19
1.45
2.8
2.0
—
—
—
0
0
(44790047)
5
16
3.19
1.45
2.8
2.0
—
—
—
0
0
(44790048)
5
16
3.19
1.45
2.8
2.0
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
6
22
2.79
1.45
1.3
1.4
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
9
40
2.32
1.42
1.9
1.2
g/l
1.3
1.1
—
9
40
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
19
113
1.77
1.39
2.2
2.2
ug/l
11.4
5.0
0.57
14
92
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
17
3.00
1.37
1.0
1.2
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
20
123
1.72
1.32
1.7
1.5
%
1.5
1.4
0.46
15
108
(3021901) Oxygen saturation in Capillary blood
6
24
2.56
1.31
3.8
5.7
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
9
44
2.11
1.29
1.1
1.3
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
9
44
2.11
1.29
1.1
1.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
9
44
2.11
1.29
1.1
1.3
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
19
2.68
1.22
1.0
1.2
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
12
64
1.95
1.21
1.2
1.2
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
31
218
1.53
1.21
4.7
2.9
mmol/l
2.5
2.4
1.53
23
188
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
6
26
2.36
1.20
1.2
1.1
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
33
0.00
1.17
0.0
1.6
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
35
0.00
1.16
0.0
4.7
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
18
112
1.69
1.15
4.8
3.3
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
7
30
2.39
1.14
1.6
1.4
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
7
30
2.39
1.14
1.0
1.3
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
8
40
2.05
1.14
1.8
2.1
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
16
99
1.69
1.04
14.9
2.8
mmol/l
1.2
1.2
0.45
16
86
(3021601) Nitrite [Presence] in Urine by Test strip
72
606
1.35
1.04
6.5
5.0
estimate
0.0
0.0
0.00
21
120
(3005033) Fetal Nuchal fold Thickness US
0
31
0.00
0.97
0.0
1.5
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
31
0.00
0.97
0.0
1.5
—
—
—
0
0
(3015736) pH of Urine
58
477
1.34
0.96
3.7
3.4
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
6
28
2.19
0.92
1.8
1.2
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
8
42
1.95
0.90
1.9
1.6
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
72
617
1.31
0.88
4.6
3.7
estimate
0.0
0.0
0.00
21
112
(36660697) Celiac disease serology panel - Serum
14
88
1.65
0.87
1.1
1.1
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
71
611
1.29
0.83
4.6
3.7
estimate
0.0
0.0
0.00
21
119
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
6
32
1.91
0.82
2.5
1.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
18
124
1.51
0.79
1.4
1.2
—
—
—
0
0
(3013512) EKG study
44
357
1.32
0.79
5.1
3.9
—
—
—
0
0
(3000492) Spirometry study
14
91
1.59
0.78
1.6
1.7
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
6
34
1.79
0.77
1.7
1.4
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
5
24
2.12
0.75
1.0
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
42
341
1.32
0.75
4.5
3.8
estimate
0.0
0.0
0.00
19
118
(3020891) Body temperature
7
38
1.88
0.74
7.7
3.7
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
35
281
1.32
0.67
3.6
3.6
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
120
1121
1.29
0.66
33.6
12.4
ml/min/173m2
73.7
79.9
1.47
105
898
(3000494) Fungus identified in Specimen by Culture
20
149
1.39
0.61
2.9
1.4
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
123
1158
1.28
0.60
5.4
4.8
mmol/l
2.5
2.7
1.18
114
1049
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
6
35
1.74
0.58
2.3
2.4
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
11
73
1.54
0.58
1.1
1.6
—
—
—
0
0
(3019225) pH of Specimen
16
118
1.40
0.52
8.4
4.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
41
348
1.24
0.52
4.8
3.2
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
12
85
1.45
0.48
4.5
3.7
ml/min/173m2
60.7
63.4
—
6
29
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
114
1078
1.21
0.45
4.4
3.9
mmol/l
1.4
1.2
1.57
104
979
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
27
222
1.26
0.45
3.2
2.9
ug/l
1.2
0.8
0.31
18
153
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
18
0.00
0.40
0.0
2.3
—
4.1
—
0
18
(3035285) Chloride [Moles/volume] in Venous blood
0
18
0.00
0.40
0.0
2.3
—
106.2
—
0
18
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
18
0.00
0.40
0.0
2.3
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
18
0.00
0.40
0.0
2.5
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
14
107
1.34
0.38
1.4
1.5
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
5
36
1.40
0.38
1.4
1.2
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
9
71
1.28
0.37
1.1
1.3
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
117
1120
1.17
0.34
4.7
4.3
mmol/l
1.4
1.5
1.67
109
1015
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
12
154
0.76
0.34
8.5
7.4
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
118
1131
1.17
0.33
4.8
4.3
mmol/l
4.3
4.5
1.32
109
1032
(3027273) Bicarbonate [Moles/volume] in Venous blood
7
54
1.31
0.31
5.4
4.0
mmol/l
25.8
24.9
—
7
54
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
7
57
1.24
0.29
1.4
1.5
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
117
1126
1.15
0.29
5.9
4.6
mmol/l
6.0
5.9
0.08
108
1012
(3050129) First trimester maternal screen panel - Serum or Plasma
5
37
1.36
0.24
1.6
1.4
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
7
93
0.74
0.23
1.4
1.3
—
—
—
0
0
(1002224) Polysomnography panel
5
42
1.20
0.21
1.0
1.1
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
15
175
0.84
0.20
1.6
1.4
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
51
1.18
0.19
4.0
2.4
%
1.7
1.1
—
6
51
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
20
226
0.87
0.18
1.8
1.5
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
7
58
1.22
0.18
1.9
1.9
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
51
478
1.10
0.18
4.8
3.7
—
—
—
0
0
(40761535) Cells panel - Urine sediment
12
101
1.20
0.17
2.8
3.4
—
—
—
0
0
(4010399)
7
86
0.81
0.15
1.0
1.3
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
6
53
1.14
0.09
5.2
5.6
%
34.1
43.7
—
6
53
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
12
133
0.89
0.08
2.4
2.2
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
10
112
0.89
0.07
2.3
1.8
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
8
77
1.04
0.07
2.0
2.0
—
—
—
0
0
(3022621) pH of Urine by Test strip
10
89
1.13
0.07
4.7
2.6
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
32
309
1.04
0.04
3.6
4.5
%
24.7
22.2
0.25
15
163
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
40
389
1.04
0.03
5.6
5.2
ug/l
2.2
2.6
0.29
30
342
(1761868) Lipid panel - Serum or Plasma
36
367
0.98
0.01
2.5
2.9
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
12
119
1.01
0.00
2.4
2.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
8
81
0.99
0.00
1.6
1.7
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
8
80
1.00
0.00
2.3
2.4
—
21.9
—
0
5
(3005011) Chlamydia sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3045683) HLA typing for celiac disease panel - Blood or Tissue
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
9.2
—
1335.2
—
0
5
(44813793)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
7
74
0.94
0.00
1.1
1.2
—
39.1
—
0
6
(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
0.3
—
0
5
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
53
0.94
0.00
1.6
1.5
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
6.4
—
875.0
—
0
5
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.8
—
—
—
0
0
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
7
74
0.94
0.00
1.0
1.0
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(40768443) Skin Pathology biopsy report
6
60
1.00
0.00
1.8
1.2
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(44806420)
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
3.9
—
27.0
—
0
8
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
5
0.00
0.00
0.0
1.8
—
8.9
—
0
5
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_ACQPUREREDCLLAPLASIA and mortality.

Females

Parameter HR [95% CI] p-value
D3_ACQPUREREDCLLAPLASIA 2.385 [1.8, 3.16] < 0.001
Birth year 0.998 [0.99, 1.01] 0.612

During the follow-up period (1.1.1998 — 31.12.2019), 214 out of 643 females with D3_ACQPUREREDCLLAPLASIA died.

Males

Parameter HR [95% CI] p-value
D3_ACQPUREREDCLLAPLASIA 3.507 [2.19, 5.62] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 570 males with D3_ACQPUREREDCLLAPLASIA died.

Mortality risk

Mortality risk for people of age

years, who have D3_ACQPUREREDCLLAPLASIA.

N-year risk Females Males
1 0.271% 0.578%
5 1.616% 3.729%
10 4.04% 9.649%
15 7.368% 16.673%
20 12.727% 26.796%

Relationships between endpoints

Index endpoint: D3_ACQPUREREDCLLAPLASIA – Acquired pure red cell aplasia [erythroblastopenia]

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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