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Acquired coagulation factor deficiency

DOID EFO Endpoint Browser PheWeb

D3_ACQCOAFACDEF

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D68.4
  • Hospital discharge: ICD-9 — 2867
  • Cause of death: ICD-10 — D68.4
  • Cause of death: ICD-9 — 2867

2 out of 7 registries used, show all original rules.

58

4. Check minimum number of events

None

58

5. Include endpoints

None

58

6. Filter based on genotype QC (FinnGen only)

58

Control definitions (FinnGen only)

Control exclude
D3_COAGDEF_PURPUR_HAEMORRHAGIC

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D68
Name in latin
Deficientia factoris coagulationis acquisita

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 397 225 170
Only index persons 317 190 127
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population 59.15 53.57 66.31
Only index persons 55.43 47.69 67.01

-FinnGen-

Key figures

All Female Male
Number of individuals 58 40 18
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 59.96 54.59 71.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
52
Matched controls
522
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D68.4
ICD-10 Finland
Acquired coagulation factor deficiency
+∞
61.0
46
*
D68.8
ICD-10 Finland
Other specified coagulation defects
+∞
10.8
10
*
D68.2
ICD-10 Finland
Hereditary deficiency of other clotting factors
+∞
10.8
10
*
B02AA02
ATC
tranexamic acid; systemic
6.9
7.5
20
43
2867X
ICD-9 Finland
Coagulation defects, Acquired coagulation factor deficiency[DEFECTIO COAGULATIONIS, E DEFICIENTIA NON DEFINITA]
+∞
6.4
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3006109) Coagulation factor IX activity actual/normal in Platelet poor plasma by Coagulation assay
12
0
+∞
12.98
2.0
0.0
%
109.6
—
—
12
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
16
8
26.87
11.93
11.0
1.0
%
96.1
96.8
—
16
8
(3004588) Protein electrophoresis panel - Serum or Plasma
18
33
7.46
10.19
5.2
1.2
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
36
139
5.19
8.83
7.0
3.7
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
28
91
5.02
8.43
8.0
1.7
mg/l
1.2
1.2
0.00
23
81
(3032080) INR in Blood by Coagulation assay
41
197
4.69
7.11
22.7
8.8
inr
1.4
1.2
0.85
17
64
(3049242) von Willebrand panel - Platelet poor plasma
6
0
+∞
6.35
2.5
0.0
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
22
72
4.31
6.32
6.1
2.0
umol/l
11.3
12.9
0.44
22
65
(3027945) Reticulocytes/100 erythrocytes in Blood
19
56
4.56
6.23
3.2
1.9
%
2.9
1.8
2.10
19
48
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
21
69
4.20
5.96
6.7
2.0
%
19.3
21.5
0.30
21
55
(3037522) Nuclear Ab [Titer] in Serum
19
58
4.38
5.93
1.2
1.3
titre
784.0
426.7
—
5
15
(3037756) Immunofixation for Serum or Plasma
9
8
13.01
5.50
2.9
1.3
—
—
—
0
0
(40761593) Coagulation factor VIII Ab [Presence] in Platelet poor plasma by Immunoassay
5
0
+∞
5.28
1.4
0.0
—
—
—
0
0
(43055222) Platelet function.collagen + Adenosine diphosphate induced and EPINEPHrine induced panel - Blood
5
0
+∞
5.28
3.0
0.0
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
9
9
11.55
5.23
8.7
1.9
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
49
333
4.03
4.47
5.7
4.8
—
362.0
—
0
11
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
39
226
3.22
4.25
7.5
5.1
mmol/l
1.2
1.2
0.19
30
183
(3017181) Myelocytes/100 leukocytes in Blood
14
43
3.97
4.23
7.7
3.5
%
1.3
0.7
—
6
12
(3021589) Normoblasts [#/volume] in Blood
36
204
3.02
4.00
18.3
9.9
e9/l
0.0
0.0
0.37
30
168
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
14
47
3.61
3.71
5.6
4.7
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
7
9
8.65
3.67
3.9
1.6
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
7
10
7.77
3.47
2.1
2.8
mmol/l
1.9
1.6
—
7
10
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
22
102
2.86
3.43
7.2
1.8
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
6
7
9.38
3.34
1.2
1.1
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
6
7
9.38
3.34
1.2
1.1
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
47
327
3.31
3.32
5.1
4.4
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
6
8
8.19
3.13
2.3
3.0
%
86.7
90.2
—
6
8
(40761536) Microorganisms panel - Urine sediment
13
47
3.28
3.05
6.2
4.5
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
7
13
5.96
2.96
1.3
1.3
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
6
9
7.28
2.94
1.0
1.1
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
8
18
4.97
2.91
3.1
3.3
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
5
6
8.96
2.80
1.2
1.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
29
169
2.43
2.75
3.0
3.1
—
—
—
0
0
(3018418) pH of Serum or Plasma
26
145
2.44
2.71
5.6
3.9
ph
7.4
7.4
0.57
12
29
(36304419) Bacteria [Presence] in Urine
25
138
2.43
2.65
2.8
2.8
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
6
11
5.94
2.61
2.7
1.3
g/l
0.1
0.2
—
6
11
(3024522) Salmonella sp identified in Specimen by Organism specific culture
5
7
7.67
2.60
1.2
1.1
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
5
7
7.67
2.60
1.2
1.1
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
5
7
7.67
2.60
1.2
1.1
—
—
—
0
0
(40758558) Short blood count panel - Blood
22
117
2.42
2.51
10.5
6.2
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
12
5.44
2.47
4.7
1.8
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
5
8
6.70
2.42
1.4
1.3
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
21
111
2.40
2.41
6.4
4.3
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
15
68
2.63
2.36
1.9
1.8
—
—
—
0
0
(3013512) EKG study
25
145
2.27
2.32
4.3
4.0
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
5
9
5.95
2.26
2.6
1.9
%
58.0
63.6
—
5
9
(3030905) Polymorphonuclear cells [#/volume] in Blood
5
9
5.95
2.26
1.6
1.9
e9/l
4.2
5.6
—
5
9
(3013290) Carbon dioxide [Partial pressure] in Blood
6
14
4.65
2.21
10.0
4.7
kpa
5.1
4.9
—
6
14
(3027315) Oxygen [Partial pressure] in Blood
6
14
4.65
2.21
10.0
4.7
kpa
8.2
8.2
—
6
14
(3044640) Blood type and Crossmatch panel - Blood
25
149
2.19
2.14
8.6
2.0
—
—
—
0
0
(1616796) Gas panel - Central venous blood
5
10
5.35
2.11
7.6
4.7
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
8
26
3.40
2.10
9.3
4.0
mmol/l
25.8
24.8
—
8
26
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
19
102
2.28
2.07
6.7
2.7
mmol/l
2.4
2.5
0.76
19
90
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
7
21
3.64
2.03
2.6
1.0
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
5
11
4.86
1.98
1.0
1.4
—
—
—
0
0
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
6
17
3.81
1.89
2.7
1.0
g/l
0.0
0.0
—
6
17
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
6
17
3.81
1.89
2.7
1.0
g/l
0.0
0.0
—
6
17
(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis
6
17
3.81
1.89
2.7
1.0
g/l
1.2
0.1
—
6
17
(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis
6
17
3.81
1.89
2.7
1.0
g/l
0.0
0.0
—
6
17
(3042936) Bacteria identified in Isolate by Culture
13
61
2.46
1.88
3.4
2.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
31
210
2.02
1.83
2.0
2.0
pmol/l
97.0
96.1
0.04
24
91
(40768443) Skin Pathology biopsy report
7
24
3.17
1.78
1.3
1.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
32
221
2.00
1.78
8.3
3.9
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
28
186
1.98
1.72
4.9
4.2
ng/l
35.0
35.2
0.01
21
130
(40768804) Tissue Pathology biopsy report
29
196
1.96
1.69
2.8
2.0
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
27
179
1.95
1.66
3.4
3.9
e6/l
279.0
79.4
0.54
22
126
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
5
15
3.54
1.55
8.0
1.7
mmol/l
26.9
25.1
—
5
15
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
6
21
3.06
1.55
2.0
1.1
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
22
139
1.94
1.53
5.5
3.9
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
19
116
1.95
1.45
1.9
1.7
nmol/l
1185.2
1247.2
0.12
19
89
(3000492) Spirometry study
7
29
2.60
1.44
1.0
1.3
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
7
29
2.60
1.44
1.3
1.3
—
—
—
0
0
(3003338) MCHC [Mass/volume]
29
375
0.55
1.41
45.9
18.7
g/l
327.5
330.6
1.14
29
375
(3003694) ABO and Rh group [Type] in Blood
18
109
1.94
1.40
1.6
1.5
—
—
—
0
0
(3019225) pH of Specimen
10
48
2.31
1.37
7.1
2.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
10
48
2.31
1.37
2.2
1.5
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
18
2.94
1.31
2.0
2.2
—
—
—
0
0
(3022313) Gas panel - Capillary blood
5
19
2.78
1.24
7.8
1.5
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
17
107
1.83
1.16
10.4
4.7
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
10
52
2.12
1.14
5.8
3.6
mmol/l
1.0
1.0
—
10
47
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
21
2.51
1.11
3.6
1.9
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
11
62
1.96
1.02
1.2
1.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
5
104
0.43
1.01
4.2
3.8
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
0
30
0.00
1.00
0.0
1.3
—
—
—
0
0
(4035726)
9
51
1.90
1.00
1.6
1.2
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
10
56
1.95
0.95
8.6
5.1
ug/l
3.8
11.8
—
10
42
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
8
46
1.86
0.87
1.8
1.5
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
8
46
1.86
0.87
1.8
1.6
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
27
0.00
0.79
0.0
1.2
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
19
139
1.55
0.73
6.0
4.5
estimate
0.0
0.0
0.00
12
52
(3017143) Hepatitis C virus Ab [Presence] in Serum
7
41
1.80
0.73
1.7
1.4
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
52
478
1.85
0.70
36.7
13.8
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
6
103
0.53
0.70
1.3
1.2
—
0.7
—
0
35
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
24
187
1.48
0.69
5.7
4.3
—
—
—
0
0
(3019060) Gas panel - Arterial blood
5
28
1.86
0.68
2.2
4.2
—
—
—
0
0
(3002256) Pathology report gross observation
8
50
1.69
0.65
1.1
1.2
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
0
19
0.00
0.61
0.0
3.1
—
24.0
—
0
19
(3022145) Colonoscopy Study observation
9
61
1.56
0.57
1.0
1.4
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
9
62
1.53
0.56
1.7
1.5
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
11
75
1.58
0.55
1.3
1.9
—
—
—
0
0
(40761535) Cells panel - Urine sediment
6
40
1.56
0.53
2.5
3.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
45
407
1.47
0.52
30.4
14.5
%
36.8
39.2
0.80
27
278
(3035350) Ketones [Presence] in Urine by Test strip
29
244
1.38
0.52
5.2
4.0
estimate
0.0
0.0
0.00
12
55
(3019832) Treponema pallidum Ab [Presence] in Serum
7
45
1.63
0.51
1.1
1.8
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
29
246
1.36
0.48
5.3
4.1
estimate
0.0
0.0
0.00
11
50
(1761868) Lipid panel - Serum or Plasma
12
158
0.70
0.45
4.0
2.9
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
5
32
1.61
0.43
1.0
1.5
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
(4034850)
0
16
0.00
0.42
0.0
12.7
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
0
17
0.00
0.41
0.0
3.4
—
41.4
—
0
17
(3000330) Specific gravity of Urine by Test strip
0
17
0.00
0.41
0.0
2.9
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
17
137
1.34
0.38
2.4
2.5
u/l
57.1
57.3
0.01
17
128
(3021601) Nitrite [Presence] in Urine by Test strip
28
243
1.29
0.37
6.5
5.3
estimate
0.0
0.0
0.00
12
53
(3012516) Albumin [Mass/volume] in Urine
15
123
1.30
0.29
3.1
3.1
mg/l
29.9
63.5
—
7
76
(3020682) Albumin/Creatinine [Ratio] in Urine
16
134
1.27
0.26
4.7
3.8
mg/mmol
3.3
7.6
—
7
77
(3014111) Lactate [Moles/volume] in Serum or Plasma
5
37
1.38
0.24
3.8
3.6
mmol/l
1.5
1.4
—
5
37
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
5
39
1.31
0.23
2.0
2.4
u/l
22.0
36.7
—
5
31
(3023511) Choriogonadotropin [Units/volume] in Urine
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.6
—
45.2
—
0
11
(1761482) Bacteria [#/volume] in Urine by Culture
0
11
0.00
0.21
0.0
4.3
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
11
0.00
0.21
0.0
4.3
—
23.6
—
0
11
(3026389) Candida sp identified in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3047181) Lactate [Moles/volume] in Blood
0
12
0.00
0.21
0.0
6.4
—
1.1
—
0
12
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
17
147
1.22
0.21
2.6
2.5
u/l
24.9
30.0
0.95
17
140
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
49
1.25
0.21
1.8
2.1
—
—
—
0
0
(3007930) Methemoglobin/Hemoglobin.total in Blood
0
14
0.00
0.20
0.0
4.2
—
1.0
—
0
14
(4094501)
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
6
52
1.17
0.20
2.3
1.4
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
5
67
0.72
0.18
1.8
2.7
ug/l
0.4
0.8
—
5
45
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
30
280
1.15
0.14
3.3
3.4
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
5
48
1.05
0.09
2.0
1.9
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
8
76
1.06
0.08
1.9
1.6
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
8
90
0.87
0.07
1.4
1.4
—
—
—
0
0
(3015736) pH of Urine
20
188
1.10
0.06
3.8
3.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
17
169
1.01
0.00
5.2
2.8
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
4.7
—
1.5
—
0
6
(3023419) Bacteria identified in Sputum by Culture
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
4.7
—
7.8
—
0
6
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3039000) Anion gap in Blood
0
7
0.00
0.00
0.0
6.6
—
9.9
—
0
7
(3014051) Protein [Presence] in Urine by Test strip
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044889) 12 lead EKG panel
33
330
1.00
0.00
4.8
3.9
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3018572) Chloride [Moles/volume] in Blood
0
7
0.00
0.00
0.0
6.6
—
104.4
—
0
7
(3039443) Prostate specific Ag panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4146454)
0
7
0.00
0.00
0.0
3.4
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
0
9
0.00
0.00
0.0
1.0
—
0.9
—
0
9
(3000764) Benzodiazepines [Presence] in Urine
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
0
7
0.00
0.00
0.0
1.6
—
223.9
—
0
7
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint D3_ACQCOAFACDEF and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have D3_ACQCOAFACDEF.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: D3_ACQCOAFACDEF – Acquired coagulation factor deficiency

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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