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Cytomegaloviral pneumonitis

DOID Endpoint Browser PheWeb

CMV_PNEUMONIA

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

58

4. Check minimum number of events

None

58

5. Include endpoints

None

58

6. Filter based on genotype QC (FinnGen only)

58

Control definitions (FinnGen only)

Control exclude
IBD_CMV

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 414 182 224
Only index persons 268 122 146
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.00 0.01
Median age at first event (years)
Whole population 59.56 58.58 60.46
Only index persons 63.16 60.88 65.06

-FinnGen-

Key figures

All Female Male
Number of individuals 58 23 35
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 65.03 59.17 68.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
54
Matched controls
539
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J17.1*B25.0
ICD-10 Finland
Cytomegaloviral pneumonitis
+∞
42.3
35
*
B25.0
ICD-10 Finland
Cytomegaloviral pneumonitis
+∞
23.7
21
*
TGC00
NOMESCO Finland
Bronchial lavation
51.2
17.2
20
6
UGC12
NOMESCO Finland
Flexible bronchoscopy
20.5
15.6
24
20
J18.9
ICD-10 Finland
Pneumonia, unspecified
10.8
14.4
38
97
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
16.8
12.4
20
18
127
Kela drug reimbursment
Transplant complication
55.6
11.5
13
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
9.2
11.2
45
190
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
17.0
10.8
17
14
H02AB04
ATC
methylprednisolone; systemic
9.4
10.6
24
42
L04AD01
ATC
ciclosporin; systemic
33.3
10.4
13
5
TK800
NOMESCO Finland
Hemodialysis
33.3
10.4
13
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.7
9.9
27
62
L04AA06
ATC
mycophenolic acid; systemic
37.6
9.9
12
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
120.0
9.7
10
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
+∞
9.6
9
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
9.8
9.1
19
28
JN4AD
NOMESCO Finland
Body CT examination
10.7
8.7
17
22
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
105.7
8.7
9
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
29.9
7.9
10
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
8.1
7.8
18
31
C03CA01
ATC
furosemide; systemic
5.2
7.8
33
124
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.4
7.7
16
23
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
92.1
7.6
8
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.9
7.6
20
42
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
9.9
7.5
15
20
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
+∞
7.4
7
*
R50.9
ICD-10 Finland
Fever, unspecified
6.6
7.3
20
44
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
11.0
7.0
13
15
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.9
7.0
21
52
XW000
NOMESCO Finland
Bone marrow biopsy
10.3
6.8
13
16
WX872
NOMESCO Finland
Intensive care
11.5
6.7
12
13
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
17.1
6.7
10
7
J01MA12
ATC
levofloxacin; systemic
5.0
6.2
22
65
L04AX01
ATC
azathioprine; systemic
11.1
6.1
11
12
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
7.0
6.1
15
28

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
31
15
43.25
43.88
3.1
1.5
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
30
15
40.36
41.79
3.1
1.5
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
25
11
39.19
36.06
2.5
1.5
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
23
10
37.46
33.11
2.2
1.5
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
22
11
31.61
29.90
6.2
2.0
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
19
10
27.77
25.01
2.3
1.6
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
33
52
13.40
22.99
4.3
2.0
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
32
50
13.05
22.36
3.8
1.9
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
38
78
12.23
21.20
4.6
2.0
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
18
12
21.30
21.14
3.2
1.3
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
17
11
21.45
20.19
3.0
1.2
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
22
8
42.97
18.18
2.1
1.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
24
34
11.34
17.60
15.5
4.4
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
32
69
9.11
16.42
3.5
1.7
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
27
56
8.15
14.07
17.8
8.1
mmol/l
1.2
1.5
0.16
16
41
(3023368) Bacteria identified in Blood by Culture
41
130
8.35
14.07
12.6
5.2
—
—
—
0
0
(44806118)
17
6
39.08
13.91
3.2
1.7
—
—
—
0
0
(44790049)
17
6
39.08
13.91
3.2
1.7
—
—
—
0
0
(44790048)
17
6
39.08
13.91
3.2
1.7
—
—
—
0
0
(44790047)
17
6
39.08
13.91
3.2
1.7
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
20
31
9.32
13.35
2.8
1.5
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
18
26
9.59
12.66
25.2
7.7
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
16
7
30.74
12.38
2.6
1.6
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
16
7
30.74
12.38
2.6
1.6
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
16
9
23.87
11.52
2.4
2.3
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
14
5
36.01
11.34
1.8
1.6
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
42
162
6.77
10.91
20.7
5.3
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
20
39
7.30
10.74
8.1
3.5
%
0.3
0.6
—
6
10
(3028433) Virus identified in Specimen by Culture
10
0
+∞
10.74
1.3
0.0
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
11
10
13.34
10.48
1.9
1.2
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
23
53
6.53
10.47
9.3
3.5
mmol/l
-0.0
2.3
2.05
14
36
(3000494) Fungus identified in Specimen by Culture
24
59
6.23
10.19
3.2
1.5
—
—
—
0
0
(3012544) pH of Venous blood
23
55
6.27
10.03
11.0
3.5
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
13
6
27.27
9.86
2.0
1.3
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
25
68
5.70
9.42
5.0
2.3
%
24.7
21.3
0.49
17
60
(46235355) HIV 1 and 2 tests - Meaningful Use set
25
69
5.61
9.25
2.0
1.8
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
10
11
10.78
8.33
2.1
1.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
35
138
4.87
8.22
14.1
4.2
ph
7.4
7.4
—
7
32
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
12
8
18.45
8.13
3.7
1.3
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
19
46
5.66
8.00
8.7
3.4
%
1.1
1.1
—
7
19
(40760888) Immunoglobulin light chains.free panel - Serum
10
12
9.86
7.82
3.3
3.7
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
46
236
5.59
7.44
36.5
6.7
mmol/l
1.2
1.2
0.35
39
190
(3020229) Cytomegalovirus DNA [Presence] in Specimen by NAA with probe detection
7
0
+∞
7.44
1.4
0.0
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
10
5
23.66
7.42
1.9
1.4
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
47
247
5.76
7.33
19.5
5.9
e9/l
0.2
0.2
0.85
42
227
(3006315) Basophils [#/volume] in Blood
46
242
5.35
7.05
17.2
5.8
e9/l
0.0
0.0
0.08
40
218
(3004588) Protein electrophoresis panel - Serum or Plasma
15
33
5.78
6.92
2.3
2.4
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
16
38
5.43
6.79
2.4
2.6
g/l
66.2
65.7
0.05
11
32
(3017143) Hepatitis C virus Ab [Presence] in Serum
19
53
4.84
6.71
2.9
1.8
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
45
241
4.87
6.52
17.5
5.7
e9/l
0.8
0.6
1.05
39
215
(3032080) INR in Blood by Coagulation assay
42
215
4.46
6.45
24.6
7.5
inr
1.1
1.2
—
10
74
(3019198) Lymphocytes [#/volume] in Blood
46
252
4.99
6.43
18.5
5.7
e9/l
4.1
1.8
0.60
40
230
(3024561) Albumin [Mass/volume] in Serum or Plasma
43
227
4.46
6.25
27.2
3.7
g/l
32.2
35.0
1.84
37
210
(3021879) Hepatitis B virus core Ab [Presence] in Serum
14
33
5.27
5.94
2.1
1.7
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
50
318
5.14
5.87
12.4
4.4
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
8
5
18.20
5.58
2.0
1.2
—
—
—
0
0
(3024471) HLA-A [Type]
5
0
+∞
5.28
1.0
0.0
—
—
—
0
0
(3024932) HLA-DR beta [Type]
5
0
+∞
5.28
1.2
0.0
—
—
—
0
0
(3026250) Tacrolimus [Mass/volume] in Blood
5
0
+∞
5.28
30.4
0.0
ug/l
7.4
—
—
5
0
(3042733) HLA Ab [Presence] in Serum
5
0
+∞
5.28
4.6
0.0
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
8
6
15.16
5.24
1.6
1.8
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
8
6
15.16
5.24
1.6
1.8
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
8
6
15.16
5.24
1.6
1.8
—
—
—
0
0
(3009343) pH of Capillary blood
13
32
4.95
5.21
11.2
3.4
—
7.4
—
0
8
(3007853) Bacteria identified in Skin by Aerobe culture
17
54
4.04
4.96
2.4
1.6
—
—
—
0
0
(3000991) Gas panel - Venous blood
15
44
4.25
4.85
10.1
6.9
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
18
61
3.83
4.80
2.7
1.6
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
39
216
3.46
4.78
15.8
3.7
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
9
12
8.63
4.54
2.9
1.0
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
8
9
10.07
4.43
1.5
1.1
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
16
55
3.64
4.13
8.7
3.1
umol/l
23.9
8.9
0.60
11
48
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
7
7
11.14
4.13
4.1
1.1
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
29
147
2.95
3.93
6.4
3.3
mg/l
2030.7
70.6
0.52
21
97
(3042111) Morphology [Interpretation] in Bone marrow Narrative
7
8
9.74
3.89
2.6
1.6
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
7
8
9.74
3.89
1.9
1.1
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
5
13.15
3.85
2.5
1.4
—
—
—
0
0
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
6
5
13.15
3.85
1.3
3.0
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
6
5
13.15
3.85
1.8
1.2
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
6
5
13.15
3.85
2.8
1.0
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
8
12
7.53
3.81
1.5
1.3
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
25
119
2.93
3.77
1.5
1.5
nmol/l
15.5
20.9
2.04
20
95
(3021440) Promyelocytes/100 leukocytes in Blood
13
41
3.80
3.76
9.7
3.5
%
0.0
0.3
—
7
15
(40760892) CBC W Ordered Manual Differential panel - Blood
24
112
2.95
3.74
12.0
5.5
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
9
18
5.71
3.53
15.0
3.8
mmol/l
24.5
25.4
—
9
18
(3001122) Ferritin [Mass/volume] in Serum or Plasma
33
190
2.71
3.38
4.9
2.3
ug/l
333.8
149.6
1.53
33
167
(3030467) Casts [#/volume] in Urine by Automated count
26
133
2.73
3.36
4.5
2.8
e6/l
0.6
0.4
0.15
20
103
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
7
9.38
3.34
14.0
2.0
%
53.5
61.6
—
6
7
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
33
191
2.69
3.33
1.9
1.9
pmol/l
97.3
96.5
0.04
18
96
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
31
174
2.68
3.33
7.1
3.0
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
22
104
2.80
3.29
2.0
1.5
g/l
2.3
2.5
0.21
15
56
(3022313) Gas panel - Capillary blood
9
20
5.12
3.27
14.0
3.6
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
27
143
2.66
3.24
4.1
2.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
27
145
2.61
3.13
4.4
2.9
e6/l
37.2
37.8
0.01
21
113
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
7
12
6.46
3.12
1.3
1.3
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
5
5
10.76
3.03
1.2
1.2
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
29
165
2.52
2.94
5.7
3.5
e6/l
9.1
39.8
1.63
21
120
(3025159) Blasts/100 leukocytes in Blood
11
37
3.43
2.87
11.9
3.7
%
0.0
0.0
—
6
12
(3017817) Protein [Mass] in Urine collected for unspecified duration
5
6
8.96
2.80
1.2
7.0
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
16
69
2.82
2.79
3.8
2.8
e6/l
1.2
2.9
—
9
37
(3019309) Folate [Moles/volume] in Red Blood Cells
20
99
2.56
2.67
1.9
1.7
nmol/l
1170.1
1362.9
0.36
15
74
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
16
71
2.73
2.64
3.8
2.6
e6/l
0.6
0.7
—
9
39
(3030905) Polymorphonuclear cells [#/volume] in Blood
5
7
7.67
2.60
7.6
2.0
e9/l
4.2
4.8
—
5
7
(3024928) Oxygen saturation in Venous blood
5
7
7.67
2.60
4.2
2.3
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
49
382
2.82
2.50
33.8
7.4
u/l
101.2
80.4
0.50
49
356
(3013707) Erythrocyte sedimentation rate by Westergren method
47
361
2.59
2.16
13.9
4.1
mm/h
26.2
11.8
3.80
47
319
(3003694) ABO and Rh group [Type] in Blood
21
117
2.25
2.11
1.7
1.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
24
142
2.18
2.08
5.1
3.0
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
19
102
2.28
2.07
4.2
2.3
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
33
222
2.13
2.06
25.6
12.0
e9/l
0.0
0.0
0.50
20
190
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
7
21
3.64
2.03
1.6
4.5
u/ml
62.7
433.4
—
7
16
(36304419) Bacteria [Presence] in Urine
22
127
2.18
2.02
5.0
2.9
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
5
11
4.86
1.98
1.4
1.5
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
9
35
2.85
1.90
12.4
5.3
mmol/l
24.5
25.2
—
9
35
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
6
18
3.59
1.79
4.5
2.3
—
—
—
0
0
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
5
13
4.10
1.75
1.0
1.2
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
6
19
3.40
1.71
1.8
1.2
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
25
160
1.99
1.70
7.3
4.2
mg/mmol
51.6
11.1
0.52
20
100
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
5
14
3.80
1.65
6.6
2.2
u/ml
65.2
77.2
—
5
14
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
12
59
2.30
1.57
5.6
3.4
—
—
—
0
0
(40761535) Cells panel - Urine sediment
9
39
2.54
1.51
10.6
3.3
—
—
—
0
0
(3020891) Body temperature
6
22
2.92
1.47
3.3
5.6
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
5
16
3.32
1.47
1.2
1.3
—
—
—
0
0
(1616796) Gas panel - Central venous blood
5
16
3.32
1.47
4.4
2.9
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
7
29
2.60
1.44
4.9
3.0
%
0.9
1.2
—
7
29
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
7
29
2.60
1.44
1.4
1.2
—
—
—
0
0
(3012501) Base excess in Blood by calculation
5
17
3.12
1.39
8.0
2.4
mmol/l
2.5
1.8
—
5
12
(3013290) Carbon dioxide [Partial pressure] in Blood
5
17
3.12
1.39
8.0
2.4
kpa
4.7
4.9
—
5
17
(3027315) Oxygen [Partial pressure] in Blood
5
17
3.12
1.39
8.0
2.4
kpa
7.7
8.7
—
5
17
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
19
118
1.91
1.37
1.7
1.6
pmol/l
515.9
472.9
0.46
12
100
(40768443) Skin Pathology biopsy report
5
18
2.94
1.31
1.0
1.2
—
—
—
0
0
(4035726)
10
51
2.16
1.19
1.3
1.3
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
8
41
2.10
1.14
2.4
3.0
u/l
20.4
30.0
—
8
33
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
29
217
1.67
1.08
5.4
3.8
ng/l
31.8
28.5
0.21
23
165
(36660697) Celiac disease serology panel - Serum
7
35
2.13
1.04
1.1
1.3
—
—
—
0
0
(40758558) Short blood count panel - Blood
19
132
1.65
0.91
11.4
6.6
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
12
73
1.81
0.90
1.4
1.6
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
19
133
1.64
0.89
5.5
3.8
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
6
31
2.04
0.87
4.5
4.3
%
49.1
46.8
—
6
31
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
23
170
1.58
0.86
4.0
2.8
ng/l
2537.1
959.5
1.13
23
135
(3013139) Helicobacter pylori Ag [Presence] in Stool
0
24
0.00
0.81
0.0
1.2
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
18
128
1.59
0.78
2.2
1.7
mmol/l
1.6
1.3
1.17
18
104
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
32
260
1.51
0.77
4.1
3.0
—
—
—
0
0
(3019225) pH of Specimen
7
38
1.96
0.77
20.0
4.5
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
40
451
0.64
0.75
47.3
13.9
ml/min/173m2
60.0
78.8
3.36
33
364
(3030981) Hyaline casts [#/volume] in Urine by Automated count
5
26
2.01
0.72
1.4
2.4
e6/l
0.0
0.1
—
5
26
(3009261) Glucose [Presence] in Urine by Test strip
30
245
1.47
0.68
6.6
3.8
estimate
0.0
0.0
—
7
48
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
28
1.86
0.68
2.2
2.1
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
10
63
1.71
0.67
19.4
30.7
—
1.5
—
0
6
(3048689) Calprotectin [Mass/mass] in Stool
8
51
1.66
0.64
13.6
1.6
ug/g
137.9
159.9
—
8
37
(3035350) Ketones [Presence] in Urine by Test strip
29
239
1.43
0.60
6.8
3.8
estimate
0.0
0.0
—
7
50
(3021601) Nitrite [Presence] in Urine by Test strip
29
245
1.37
0.50
10.4
5.2
estimate
0.0
0.0
—
7
49
(40761536) Microorganisms panel - Urine sediment
7
49
1.49
0.48
5.7
4.1
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
19
232
0.73
0.46
3.5
5.4
ug/l
1.9
2.0
0.17
19
205
(3002256) Pathology report gross observation
8
55
1.53
0.45
1.1
1.3
—
—
—
0
0
(3008898) HLA-B27 [Presence]
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
(4010399)
5
34
1.51
0.41
2.6
1.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
14
176
0.73
0.39
3.2
3.2
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
23
194
1.31
0.38
6.3
4.0
—
—
—
0
0
(3044889) 12 lead EKG panel
38
344
1.30
0.36
7.9
4.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
21
176
1.30
0.36
2.5
2.1
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
16
193
0.76
0.33
3.1
4.3
%
29.4
21.6
—
10
96
(3009542) Hematocrit [Volume Fraction] of Blood
46
432
1.31
0.29
68.2
14.4
%
36.9
39.7
1.63
25
294
(3000492) Spirometry study
5
39
1.31
0.23
2.2
1.5
—
—
—
0
0
(3013512) EKG study
19
166
1.22
0.21
5.7
4.2
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
0
10
0.00
0.21
0.0
5.2
—
41.3
—
0
5
(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay
0
12
0.00
0.21
0.0
5.5
—
20.0
—
0
12
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
6
52
1.17
0.20
3.7
5.2
ug/l
2.7
8.2
—
6
41
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
47
450
1.23
0.18
9.9
6.6
mmol/mol
42.7
40.8
0.60
42
409
(40761511) CBC panel - Blood by Automated count
52
503
1.33
0.17
63.8
14.5
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
52
503
1.33
0.17
78.5
16.6
mmol/l
4.0
4.0
0.45
52
490
(3019550) Sodium [Moles/volume] in Serum or Plasma
52
501
1.37
0.16
77.0
16.7
mmol/l
138.9
139.6
1.12
52
488
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
52
510
1.19
0.08
42.3
10.6
u/l
25.6
25.9
0.05
52
487
(3020564) Creatinine [Moles/volume] in Serum or Plasma
52
511
1.17
0.08
65.9
17.1
umol/l
122.3
80.9
2.52
52
511
(3011397) Hemoglobin [Presence] in Urine by Test strip
12
111
1.10
0.04
7.4
3.6
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
47
469
1.01
0.00
7.5
4.8
mmol/l
6.3
6.0
0.47
42
418
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
35
349
1.01
0.00
3.2
3.7
pmol/l
15.4
14.9
0.53
35
300
(3029937) Albumin [Presence] in Urine by Test strip
14
143
0.97
0.00
5.8
4.0
estimate
0.0
0.0
—
6
46
(3005570) Glucose [Moles/volume] in Urine
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
11.8
—
0
6
(3022145) Colonoscopy Study observation
5
56
0.88
0.00
2.8
1.3
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3026470) Cobalt [Mass/volume] in Blood
0
5
0.00
0.00
0.0
3.0
—
6.5
—
0
5
(3024731) MCV [Entitic volume]
53
530
1.00
0.00
90.9
21.9
fl
92.6
91.0
1.23
53
520
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
53
530
1.00
0.00
91.3
22.1
e9/l
9.6
6.6
2.87
53
513
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
6
65
0.91
0.00
11.8
8.2
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
53
530
1.00
0.00
93.0
21.9
e9/l
238.5
240.7
0.06
53
516
(3035941) MCH [Entitic mass]
53
530
1.00
0.00
90.7
21.8
pg
30.5
30.4
0.16
53
520
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
6
68
0.87
0.00
2.0
1.3
—
—
—
0
0
(4306422)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026361) Erythrocytes [#/volume] in Blood
53
530
1.00
0.00
91.1
21.9
e12/l
4.0
4.5
4.73
53
513
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
3.1
—
117.4
—
0
7
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
8
0.00
0.00
0.0
3.3
—
44.7
—
0
8
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000963) Hemoglobin [Mass/volume] in Blood
53
530
1.00
0.00
91.9
22.0
g/l
121.4
135.9
6.14
53
520
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CMV_PNEUMONIA and mortality.

Females

Parameter HR [95% CI] p-value
CMV_PNEUMONIA 10.122 [4.72, 21.71] < 0.001
Birth year 0.993 [0.98, 1.0] 0.105

During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 114 females with CMV_PNEUMONIA died.

Males

Parameter HR [95% CI] p-value
CMV_PNEUMONIA 5.501 [3.25, 9.32] < 0.001
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 111 males with CMV_PNEUMONIA died.

Mortality risk

Mortality risk for people of age

years, who have CMV_PNEUMONIA.

N-year risk Females Males
1 0.989% 1.02%
5 5.265% 5.537%
10 13.387% 14.094%
15 25.115% 23.732%
20 38.525% 37.855%

Relationships between endpoints

↥

Index endpoint: CMV_PNEUMONIA – Cytomegaloviral pneumonitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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