Chronic drug-induced interstitial lung disorders

CHRONIC_DRUGADVERS_INTERSTITIAL_LUNG_DISORD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J70.3#

1 out of 7 registries used, show all original rules.

52

4. Check minimum number of events

None

52

5. Include endpoints

None

52

6. Filter based on genotype QC (FinnGen only)

52

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 444 290 152
Only index persons 328 215 113
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population 73.02 75.38 68.75
Only index persons 71.67 74.75 65.82

-FinnGen-

Key figures

All Female Male
Number of individuals 52 29 23
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 64.70 63.82 65.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
10
12
10.08
7.85
2.0
1.0
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
34
151
4.62
6.67
14.3
5.8
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
10
16
7.50
6.20
2.6
2.2
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
41
217
5.20
6.20
13.0
6.7
e9/l
0.0
0.0
0.41
34
196
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
19
58
4.59
6.02
2.6
2.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
29
122
4.11
5.96
11.9
9.5
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
41
223
4.96
5.83
14.4
6.8
e9/l
0.2
0.2
0.20
36
204
(3001604) Monocytes [#/volume] in Blood
40
218
4.62
5.56
13.3
6.6
e9/l
0.7
0.6
0.75
34
194
(3019198) Lymphocytes [#/volume] in Blood
40
223
4.44
5.27
13.4
6.5
e9/l
2.1
1.7
0.89
34
203
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
18
58
4.22
5.25
2.6
1.9
—
—
—
0
0
(3019060) Gas panel - Arterial blood
13
33
4.92
5.06
3.6
4.2
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
14
38
4.67
5.04
2.4
2.1
ng/l
267.4
122.6
0.52
14
30
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
12
33
4.43
4.20
10.8
7.3
mmol/l
24.6
24.9
0.12
12
33
(3000492) Spirometry study
12
33
4.43
4.20
2.0
1.7
—
—
—
0
0
(3018418) pH of Serum or Plasma
30
157
3.15
3.97
6.1
4.8
ph
7.4
7.4
—
5
33
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
20
83
3.29
3.90
2.6
2.0
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
13
41
3.89
3.80
2.4
1.4
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
12
36
4.03
3.74
16.5
10.9
%
0.7
0.6
0.36
12
36
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
9
8.76
3.68
1.4
1.8
—
—
—
0
0
(3000991) Gas panel - Venous blood
13
43
3.70
3.54
14.3
10.7
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
7
10
7.88
3.48
2.1
1.2
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
10
7.88
3.48
1.6
1.7
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
27
145
2.79
3.24
4.0
3.2
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
19
85
2.95
3.19
2.9
2.8
e6/l
0.6
3.8
1.21
11
46
(3009445) Proteinase 3 Ab [Units/volume] in Serum
9
21
4.95
3.16
1.3
1.0
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
27
148
2.71
3.08
7.4
4.8
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
5
5
10.86
3.04
3.0
1.4
e9/l
4.1
5.8
—
5
5
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
11
36
3.61
3.01
17.7
10.2
%
1.4
1.2
0.36
11
36
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
14
54
3.18
3.00
2.5
4.3
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
19
90
2.75
2.83
2.6
2.7
e6/l
1.0
0.8
0.16
11
50
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
7
14
5.59
2.83
2.7
1.7
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
31
189
2.59
2.77
4.5
3.3
—
—
—
0
0
(4010399)
9
25
4.13
2.72
1.7
1.3
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
7
15
5.21
2.70
2.7
1.7
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
6
11
6.00
2.62
3.5
2.4
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
6
11
6.00
2.62
1.3
1.1
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
5
7
7.74
2.60
3.0
2.0
%
57.0
52.7
—
5
7
(3031040) Bacteria [#/volume] in Urine by Automated count
41
294
2.87
2.52
10.1
5.1
—
97.9
—
0
8
(3020891) Body temperature
8
22
4.10
2.48
5.5
4.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
42
307
2.91
2.45
9.4
4.8
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
0
62
0.00
2.43
0.0
4.3
—
30.8
—
0
36
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
13
5.06
2.34
1.5
1.2
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
5
9
6.00
2.26
2.4
1.1
g/l
0.2
0.2
—
5
9
(3022217) INR in Platelet poor plasma by Coagulation assay
13
57
2.71
2.19
39.3
19.2
—
1.5
—
0
5
(3011397) Hemoglobin [Presence] in Urine by Test strip
19
102
2.36
2.12
6.3
3.8
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
9
32
3.18
2.12
2.3
2.6
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
5
10
5.40
2.12
1.6
1.3
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
5
10
5.40
2.12
2.4
1.1
g/l
1.1
1.1
—
5
10
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
5
10
5.40
2.12
1.2
1.0
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
5
10
5.40
2.12
3.2
1.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
13
59
2.60
2.04
1.9
1.4
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
10
40
2.86
1.97
2.1
5.0
e9/l
66.5
74.9
—
5
32
(3026008) Bacteria identified in Urine by Culture
25
156
2.16
1.93
6.6
3.3
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
35
250
2.22
1.90
15.4
7.4
mmol/l
1.2
1.2
0.04
30
208
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
5
12
4.48
1.87
3.2
1.6
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
6
18
3.62
1.80
1.5
4.0
—
—
—
0
0
(3013512) EKG study
8
164
0.40
1.78
4.3
4.3
—
—
—
0
0
(3004789) Transferrin [Mass/volume] in Serum or Plasma
14
71
2.33
1.74
3.2
2.3
g/l
2.4
2.3
0.23
14
61
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
28
188
2.06
1.74
2.0
2.1
pmol/l
81.4
99.0
1.00
15
88
(40760892) CBC W Ordered Manual Differential panel - Blood
17
97
2.12
1.59
7.4
6.4
—
—
—
0
0
(3012544) pH of Venous blood
11
53
2.36
1.51
1.3
3.2
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
31
224
1.95
1.49
8.8
6.3
estimate
0.0
0.0
—
9
45
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
6
23
2.81
1.41
2.2
3.3
%
0.5
0.8
—
6
23
(3009261) Glucose [Presence] in Urine by Test strip
31
227
1.91
1.40
6.5
4.5
estimate
0.0
0.0
—
8
46
(3021589) Normoblasts [#/volume] in Blood
29
210
1.86
1.34
22.1
13.0
e9/l
0.0
0.0
0.61
23
177
(3006184) Hemoglobin [Mass/volume] in Capillary blood
5
18
2.96
1.31
1.2
2.4
—
120.4
—
0
11
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
25
2.58
1.28
2.2
3.2
%
1.3
1.5
—
6
25
(3015736) pH of Urine
25
176
1.81
1.24
5.9
4.2
—
—
—
0
0
(3044889) 12 lead EKG panel
41
338
2.01
1.20
6.9
4.3
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
13
75
1.98
1.16
2.7
1.9
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
7
31
2.45
1.15
1.6
1.2
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
7
31
2.45
1.15
6.9
4.1
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
7
31
2.45
1.15
2.1
3.2
g/l
132.3
128.7
—
7
31
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
7
31
2.45
1.15
1.3
1.9
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
10
52
2.14
1.15
1.3
1.5
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
9
46
2.15
1.11
7.7
3.8
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
5
22
2.40
1.06
1.6
3.2
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
29
221
1.71
1.04
7.4
4.5
estimate
0.0
0.0
—
9
47
(4035726)
9
51
1.92
1.01
1.2
1.2
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
31
2.05
0.87
21.8
10.1
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
0
27
0.00
0.80
0.0
3.0
—
3.5
—
0
18
(40761511) CBC panel - Blood by Automated count
42
460
0.55
0.79
27.8
16.1
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
45
479
0.55
0.73
52.9
25.6
e9/l
7.8
6.6
1.57
45
463
(3000963) Hemoglobin [Mass/volume] in Blood
45
479
0.55
0.73
53.3
25.6
g/l
130.1
133.6
0.76
45
470
(3026361) Erythrocytes [#/volume] in Blood
45
479
0.55
0.73
52.9
25.5
e12/l
4.3
4.4
0.53
45
463
(3024731) MCV [Entitic volume]
45
479
0.55
0.73
52.8
25.4
fl
92.4
91.9
0.25
45
469
(3035941) MCH [Entitic mass]
45
479
0.55
0.73
52.8
25.3
pg
30.5
30.5
0.01
45
469
(3013707) Erythrocyte sedimentation rate by Westergren method
39
337
1.63
0.73
9.6
4.6
mm/h
16.5
12.6
0.97
39
303
(3007461) Platelets [#/volume] in Blood
45
478
0.57
0.72
53.0
25.5
e9/l
251.5
244.4
0.22
45
463
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
5
28
1.87
0.68
2.8
3.4
%
44.1
39.2
—
5
28
(3027273) Bicarbonate [Moles/volume] in Venous blood
5
29
1.80
0.65
2.4
3.2
mmol/l
24.9
25.1
—
5
29
(36660697) Celiac disease serology panel - Serum
5
29
1.80
0.65
1.0
1.2
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
14
98
1.59
0.65
4.4
2.3
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
42
375
1.62
0.62
46.5
21.7
%
14.8
14.0
1.56
42
368
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
20
0.00
0.62
0.0
1.0
—
—
—
0
0
(3037121) Protein [Mass/volume] in Urine
0
20
0.00
0.62
0.0
4.5
—
0.1
—
0
10
(1761482) Bacteria [#/volume] in Urine by Culture
0
22
0.00
0.61
0.0
5.4
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
23
184
1.45
0.58
2.0
1.9
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
11
153
0.64
0.56
2.5
3.6
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
6
40
1.56
0.53
1.2
2.0
%
1.9
1.5
—
6
30
(3032080) INR in Blood by Coagulation assay
26
216
1.41
0.52
18.0
11.0
inr
1.2
1.3
—
9
74
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
45
471
0.67
0.48
28.2
12.1
u/l
24.0
24.6
0.13
45
454
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
8
58
1.45
0.44
1.0
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
16
0.00
0.42
0.0
1.7
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
16
0.00
0.42
0.0
1.4
—
47.8
—
0
16
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
17
0.00
0.41
0.0
1.9
—
—
—
0
0
(4034850)
0
17
0.00
0.41
0.0
7.4
—
—
—
0
0
(3022313) Gas panel - Capillary blood
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(40761535) Cells panel - Urine sediment
5
35
1.47
0.40
9.2
3.9
—
—
—
0
0
(3022145) Colonoscopy Study observation
7
54
1.34
0.32
1.3
1.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
25
221
1.25
0.28
2.6
2.4
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
41
384
1.32
0.27
50.3
18.6
%
38.9
39.2
0.12
28
253
(3041354) Potassium [Moles/volume] in Venous blood
0
11
0.00
0.21
0.0
2.5
—
4.0
—
0
11
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
11
0.00
0.21
0.0
2.5
—
107.8
—
0
11
(3008898) HLA-B27 [Presence]
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
0
12
0.00
0.21
0.0
2.5
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
0
14
0.00
0.20
0.0
4.2
—
26.9
—
0
7
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
6
51
1.20
0.20
1.3
1.5
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
23
207
1.20
0.20
5.6
4.2
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
45
461
0.82
0.19
42.4
20.8
umol/l
83.9
81.5
0.28
45
461
(3044640) Blood type and Crossmatch panel - Blood
16
140
1.21
0.18
5.3
2.4
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
31
328
0.86
0.14
4.6
4.3
pmol/l
15.3
15.0
0.21
26
287
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
19
173
1.15
0.13
8.6
4.9
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
16
144
1.16
0.12
2.9
4.2
mg/mmol
1.2
8.0
—
8
86
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
5
44
1.15
0.10
1.0
1.3
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
15
136
1.14
0.10
2.9
3.3
mg/l
6.0
60.8
—
8
82
(3007853) Bacteria identified in Skin by Aerobe culture
5
46
1.10
0.10
2.4
1.6
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
5
47
1.07
0.10
1.4
1.5
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
14
130
1.11
0.05
5.6
4.6
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
11
118
0.91
0.03
1.5
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
13
123
1.08
0.02
12.2
4.7
estimate
0.0
0.0
—
8
47
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
12
125
0.95
0.00
2.8
5.0
%
18.6
21.4
—
5
66
(3026179) Normetanephrine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
0.5
—
0
6
(3006270) Folate [Moles/volume] in Blood
0
6
0.00
0.00
0.0
1.0
—
418.5
—
0
6
(3004616) Nuclear Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004451) EKG impression Narrative
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
14.5
—
0
7
(4146454)
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
8
0.00
0.00
0.0
3.1
—
85.2
—
0
8
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.6
—
3.0
—
0
8
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CHRONIC_DRUGADVERS_INTERSTITIAL_LUNG_DISORD and mortality.

Females

Parameter HR [95% CI] p-value
CHRONIC_DRUGADVERS_INTERSTITIAL_LUNG_DISORD 2.051 [1.56, 2.7] < 0.001
Birth year 0.996 [0.99, 1.0] 0.297

During the follow-up period (1.1.1998 — 31.12.2019), 160 out of 262 females with CHRONIC_DRUGADVERS_INTERSTITIAL_LUNG_DISORD died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CHRONIC_DRUGADVERS_INTERSTITIAL_LUNG_DISORD.

N-year risk Females Males
1 0.17% No data
5 1.353% No data
10 3.344% No data
15 6.493% No data
20 11.182% No data

Relationships between endpoints

Index endpoint: CHRONIC_DRUGADVERS_INTERSTITIAL_LUNG_DISORD – Chronic drug-induced interstitial lung disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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