Carcinoma in situ of vulva

CD2_INSITU_VULVA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only females

-

2. Check conditions

  • not C3_VULVA
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D07.1&
  • Hospital discharge: ICD-9 2333B
  • Cause of death: ICD-10 D07.1&
  • Cause of death: ICD-9 2333B
  • Cancer registry: Topography ICD-O-3 C51
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D07
Name in latin
Carcinoma in situ penis

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 525 525 -
Only index persons 473 473 -
Unadjusted period prevalence (%)
Whole population 0.02 0.02 -
Only index persons 0.02 0.02 -
Median age at first event (years)
Whole population - 56.55 -
Only index persons - 55.59 -

-FinnGen-

Key figures

All Female Male
Number of individuals 266 266 -
Unadjusted period prevalence (%) 0.09 0.09 -
Median age at first event (years) 58.75 58.75 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
239
Matched controls
2390
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
377.0
202.9
182
20
ULA02
NOMESCO Finland
Kolposcopy
110.0
176.5
209
142
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
835.8
159.7
140
*
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
+∞
155.8
132
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
23.5
95.8
162
196
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
191.9
95.3
94
8
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
84.5
76
*
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
1123.0
83.8
77
*
LFC00
NOMESCO Finland
Partial excision of vulva
217.1
64.6
64
*
D06BB10
ATC
imiquimod; topical
29.8
55.1
75
36
LEB00
NOMESCO Finland
Biopsy of vagina
54.1
49.4
58
14
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
119.5
45.7
48
5
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
13.5
42.6
79
84
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
23.4
36.0
52
28
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
7.4
29.7
79
149
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
4.8
28.4
146
593
8070/2-C51.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vulva, NOS
+∞
26.5
25
*
N90.0
ICD-10 Finland
Mild vulvar dysplasia
101.1
25.2
27
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
16.5
23.6
38
27
LDA10
NOMESCO Finland
Curettage of cervix uteri
9.7
22.9
48
60
D07AD01
ATC
clobetasol; topical
4.8
22.1
88
260
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
+∞
20.1
19
*
115
Kela drug reimbursment
Breast cancer
+∞
20.1
19
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
17.9
17
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
17.9
17
*
N90.4
ICD-10 Finland
Leukoplakia of vulva
36.2
16.0
20
6
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
5.4
15.8
50
111
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
7.2
15.7
39
63
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
85.5
14.8
16
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
14.7
14
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
14.7
14
*
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
+∞
13.7
13
*
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
148.1
13.6
14
*
N76.6
ICD-10 Finland
Ulceration of vulva
27.6
13.6
18
7
N87.0
ICD-10 Finland
Mild cervical dysplasia
9.4
13.2
27
32
B01AB10
ATC
tinzaparin; parenteral
6.9
12.8
32
52
HAC20
NOMESCO Finland
Total mastectomy
+∞
12.6
12
*
XX3DW
NOMESCO Finland
Time consuming IT work
6.6
11.7
30
51
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
11.5
11
*
D06BB04
ATC
podophyllotoxin; topical
7.5
11.5
27
40
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
11.4
96
464
H02AB02
ATC
dexamethasone; systemic
18.2
11.4
17
10
HA1AA
NOMESCO Finland
X-ray mammography
6.9
11.3
28
45
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.1
11.1
70
279
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.2
10.9
43
119
HAB40
NOMESCO Finland
Wedge excision of mammary gland
22.7
10.8
15
7
WF002
NOMESCO Finland
Radical radiotherapy
+∞
10.5
10
*
2333B
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Other and unspecified female genital organs[CARCINOMA IN SITU VULVAE]
+∞
10.5
10
*
WX320
NOMESCO Finland
Spinalanesthesy
2.9
10.4
75
325
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
24.7
10.4
14
6
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.5
10.2
26
44
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
17.7
10.0
15
9
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.3
9.7
53
191
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
15.9
9.6
15
10
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
104.0
9.5
10
*
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
22.8
9.5
13
6
L02BA01
ATC
tamoxifen; oral
+∞
9.4
9
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
9.4
9
*
130
Kela drug reimbursment
Malignant tumour
+∞
9.4
9
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.5
9.3
27
54
JN4AD
NOMESCO Finland
Body CT examination
8.2
8.8
19
25
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
8.8
8.7
18
22
N89.0
ICD-10 Finland
Mild vaginal dysplasia
51.9
8.7
10
*
WX002
NOMESCO Finland
Sedation and analgesia
2.8
8.7
64
279
N87.1
ICD-10 Finland
Moderate cervical dysplasia
7.2
8.6
20
30
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
28.7
8.6
11
*
P01AB01
ATC
metronidazole; oral, rectal
2.3
8.6
128
807
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
8.4
8
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
8.4
8
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
8.4
8
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
8.4
8
*
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
+∞
8.4
8
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
8.4
8
*
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
7.3
8.3
19
28
L02BG04
ATC
letrozole; oral
12.3
8.2
14
12
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
7.7
8.1
18
25
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.0
8.1
19
29
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
7.8
105
623
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
46.5
7.8
9
*
ZZR00
NOMESCO Finland
Flap of skin
26.0
7.6
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
7.5
100
586
J02AC01
ATC
fluconazole; systemic
2.1
7.5
144
992
LWA00
NOMESCO Finland
Repair of wound dehiscence in gynaecological surgery
82.5
7.5
8
*
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.8
7.4
15
18
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
7.3
7
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
7.3
7
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
7.3
7
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
7.3
7
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
+∞
7.3
7
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
7.3
7
*
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
+∞
7.3
7
*
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
12.6
7.2
12
10
A03FA01
ATC
metoclopramide; systemic, rectal
2.7
7.1
50
210
TQW40
NOMESCO Finland
Remowal of suture of skin
3.9
7.0
28
79
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
6.5
6.6
16
26
WX110
NOMESCO Finland
Local anesthesy
2.1
6.5
173
1324
E0000UV
ATC
NA
2.0
6.5
110
705
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
6.3
6
*
L03AA02
ATC
filgrastim; parenteral
+∞
6.3
6
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
6.3
6
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
6.3
6
*
B01AB05
ATC
enoxaparin; parenteral
2.2
6.2
74
407
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.8
6.1
16
29
X16
ICPC
Vulval symptom/complaint
10.4
6.1
11
11
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
6.1
106
682
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
6.0
83
486

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3025130) Human papilloma virus identified in Specimen
91
38
35.88
133.71
3.6
1.5
—
—
—
0
0
(4035726)
87
51
24.86
110.74
1.5
1.3
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
216
816
9.76
59.55
5.7
1.7
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
38
16
27.54
53.95
3.2
1.7
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
162
560
5.84
45.65
2.7
1.4
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
71
119
7.77
43.14
2.9
1.4
—
—
—
0
0
(3002256) Pathology report gross observation
89
193
6.43
41.98
1.4
1.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
178
965
3.55
21.52
4.5
3.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
107
463
3.19
18.17
2.2
1.8
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
125
603
3.02
17.38
2.6
1.8
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
167
1058
2.55
12.18
6.2
3.3
umol/l
9.5
10.0
0.55
158
987
(3023368) Bacteria identified in Blood by Culture
89
430
2.61
11.46
5.0
3.4
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
64
264
2.88
11.18
1.9
1.9
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
88
438
2.51
10.52
3.0
2.3
e6/l
7.0
9.4
0.37
73
388
(3037467) Urinalysis macro (dipstick) panel - Urine
215
1593
2.82
10.49
6.0
4.4
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
177
1208
2.39
10.14
10.0
6.6
e9/l
4.1
4.1
0.01
161
1041
(3007853) Bacteria identified in Skin by Aerobe culture
54
221
2.81
9.47
1.8
1.7
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
137
863
2.21
9.20
6.2
3.2
g/l
35.5
36.4
1.25
128
798
(3026782) Osmolality of Urine
80
403
2.41
9.15
3.0
2.5
mosm/kgh2o
499.2
517.4
0.29
69
348
(3002582) Erythrocytes [#/volume] in Urine
109
631
2.23
8.97
3.7
2.9
e6/l
21.2
42.2
1.10
94
475
(3018095) Leukocytes [#/volume] in Urine
123
763
2.14
8.37
4.2
3.6
e6/l
30.0
87.0
2.25
97
513
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
215
1679
2.46
7.91
9.3
5.0
u/l
79.1
75.2
0.73
208
1540
(3030467) Casts [#/volume] in Urine by Automated count
99
578
2.14
7.76
3.8
2.8
e6/l
0.1
0.5
3.60
80
424
(36304419) Bacteria [Presence] in Urine
98
576
2.11
7.50
3.9
2.8
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
142
968
2.00
7.13
5.9
4.4
mmol/l
1.2
1.2
0.51
124
863
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
116
740
2.01
7.00
4.1
2.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
121
784
2.00
6.98
2.9
3.0
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
152
1067
1.99
6.95
6.7
5.0
mmol/l
1.2
1.2
1.14
124
910
(3032080) INR in Blood by Coagulation assay
121
788
1.98
6.85
16.5
7.4
inr
1.3
1.2
0.66
31
250
(40768793) Breast Pathology biopsy report
15
32
4.91
6.77
1.2
1.1
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
49
225
2.44
6.72
2.8
1.7
umol/l
4.9
4.8
0.06
42
191
(40768443) Skin Pathology biopsy report
28
97
3.11
6.54
1.4
1.1
—
—
—
0
0
(3018418) pH of Serum or Plasma
103
651
1.95
6.22
4.9
2.9
ph
7.4
7.4
0.88
19
112
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
33
132
2.71
5.97
1.6
1.5
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
150
1096
1.85
5.61
7.6
5.1
e9/l
0.0
0.0
0.85
137
931
(3001604) Monocytes [#/volume] in Blood
149
1087
1.84
5.59
7.6
5.1
e9/l
0.6
0.6
0.04
137
928
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
93
586
1.90
5.56
3.0
2.7
ng/l
1037.7
920.6
0.12
79
484
(3013115) Eosinophils [#/volume] in Blood
153
1133
1.82
5.40
7.7
5.6
e9/l
0.2
0.2
0.36
142
991
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
76
454
1.94
5.29
1.7
1.5
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
104
688
1.84
5.29
3.6
2.0
u/l
56.2
57.2
0.11
97
628
(3002030) Lymphocytes/100 leukocytes in Blood
143
1044
1.80
5.23
8.0
5.4
%
27.6
29.3
1.12
137
965
(42870588) Differential panel, method unspecified - Blood
106
708
1.83
5.21
8.1
5.4
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
162
1231
1.81
5.15
4.8
3.7
mmol/l
6.6
6.5
0.23
154
1133
(3019198) Lymphocytes [#/volume] in Blood
150
1116
1.79
5.10
7.7
5.1
e9/l
1.9
1.9
0.37
139
974
(3019069) Monocytes/100 leukocytes in Blood
140
1023
1.78
5.04
8.2
5.6
%
8.3
8.1
0.20
134
947
(3022096) Basophils/100 leukocytes in Blood
135
979
1.77
4.97
8.1
5.3
%
0.6
0.7
1.36
128
897
(3018010) Neutrophils/100 leukocytes in Blood
141
1036
1.77
4.95
7.5
5.2
%
58.3
56.6
0.93
134
959
(40758558) Short blood count panel - Blood
82
514
1.86
4.89
6.7
5.2
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
154
1165
1.76
4.85
4.5
3.6
estimate
0.0
0.0
0.50
33
208
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
20
68
3.10
4.83
1.3
2.2
g/l
2.2
1.7
0.67
15
59
(3006504) Eosinophils/100 leukocytes in Blood
138
1020
1.73
4.65
8.0
5.3
%
2.9
2.9
0.06
132
937
(3021601) Nitrite [Presence] in Urine by Test strip
152
1155
1.74
4.63
5.5
5.1
estimate
0.0
0.0
0.50
32
201
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
55
310
1.98
4.48
2.1
1.7
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
42
215
2.13
4.42
1.8
1.4
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
14
41
3.55
4.24
1.1
1.8
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
104
725
1.71
4.23
4.1
1.9
mmol/l
2.4
2.4
0.62
90
608
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
250
2259
2.77
4.09
20.9
11.1
mg/l
22.9
19.0
1.04
213
1718
(3044889) 12 lead EKG panel
191
1577
1.75
4.04
4.5
3.6
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
259
2420
3.67
3.97
22.0
12.4
umol/l
72.2
68.9
0.78
259
2420
(3009343) pH of Capillary blood
24
102
2.49
3.87
5.0
3.2
ph
7.4
7.4
—
6
18
(3051651) Icteric interference index of Serum or Plasma
7
8
8.95
3.79
1.7
1.4
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
76
500
1.73
3.74
1.5
1.7
mg/l
0.8
0.9
0.21
58
376
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
19
74
2.69
3.64
1.9
1.6
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
15
51
3.06
3.63
1.5
1.7
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
36
188
2.06
3.60
4.6
5.6
mmol/l
0.1
1.9
1.76
24
150
(3052851) Hemolysis interference index of Serum or Plasma
15
52
3.00
3.52
2.9
3.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
77
519
1.68
3.44
3.9
3.4
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
56
346
1.78
3.40
3.2
2.5
e6/l
1.2
1.4
0.13
40
178
(3022217) INR in Platelet poor plasma by Coagulation assay
41
230
1.93
3.36
28.1
20.1
inr
1.3
1.3
—
7
42
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
240
2165
2.11
3.34
17.7
9.9
ml/min/173m2
80.9
80.8
0.02
224
1732
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
39
217
1.93
3.28
2.1
1.5
%
1.3
1.3
0.15
34
192
(1616796) Gas panel - Central venous blood
11
33
3.43
3.23
11.6
1.9
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
61
392
1.72
3.23
3.9
4.0
ng/l
122.5
118.0
0.02
39
291
(3009508) Creatinine [Moles/volume] in Urine
96
697
1.59
3.15
5.6
2.9
mmol/l
5.8
6.7
1.30
81
579
(3022145) Colonoscopy Study observation
40
228
1.89
3.13
1.4
1.3
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
96
699
1.58
3.10
4.4
2.4
u/l
30.8
27.7
0.90
89
670
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
44
264
1.80
2.93
2.3
1.9
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
255
2378
2.75
2.93
19.5
10.9
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
7
13
5.50
2.88
1.0
1.2
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
17
71
2.49
2.86
1.8
1.6
—
—
—
0
0
(3019225) pH of Specimen
38
220
1.85
2.84
3.4
3.9
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
22
104
2.22
2.84
1.6
1.9
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
90
660
1.55
2.77
4.6
3.0
mg/l
106.0
354.8
0.71
63
380
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
5
6
8.46
2.76
2.2
1.8
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
7
14
5.10
2.74
1.9
2.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
76
538
1.58
2.73
1.5
1.4
—
—
—
0
0
(3000991) Gas panel - Venous blood
24
120
2.10
2.71
7.3
6.1
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
201
1757
1.59
2.68
6.0
4.4
mm/h
13.9
11.8
1.23
188
1618
(3019060) Gas panel - Arterial blood
21
100
2.19
2.67
6.6
4.7
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
141
1147
1.49
2.62
4.4
3.6
estimate
0.0
0.0
0.00
31
209
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
7
15
4.76
2.61
1.1
1.1
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
81
587
1.55
2.61
4.8
3.7
estimate
0.0
0.0
0.50
33
206
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
9
25
3.69
2.60
1.0
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
12
44
2.81
2.58
1.8
2.5
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
5
7
7.25
2.56
1.8
1.1
ug/l
14.8
13.1
—
5
7
(3015736) pH of Urine
115
901
1.49
2.55
3.6
3.4
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
10
33
3.11
2.55
1.0
1.4
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
217
1941
1.64
2.53
5.4
4.5
pmol/l
14.8
14.7
0.40
199
1785
(3017732) Neutrophils [#/volume] in Blood
29
160
1.91
2.51
3.8
2.6
e9/l
4.7
3.9
0.85
19
125
(3000494) Fungus identified in Specimen by Culture
44
277
1.71
2.49
1.4
1.3
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
69
488
1.56
2.46
1.6
1.3
g/l
2.1
2.3
0.63
36
283
(3022313) Gas panel - Capillary blood
16
70
2.37
2.46
5.3
3.5
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
122
973
1.47
2.45
12.6
7.9
e9/l
0.0
0.0
0.18
104
786
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
10
34
3.02
2.44
1.0
1.1
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
10
34
3.02
2.44
1.2
1.3
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
176
1509
1.49
2.43
4.0
2.8
u/l
54.9
37.9
1.52
168
1413
(3020682) Albumin/Creatinine [Ratio] in Urine
91
686
1.50
2.42
5.4
3.7
mg/mmol
18.9
5.3
0.93
58
394
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
45
288
1.68
2.40
4.0
4.7
%
33.4
33.6
0.02
29
180
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
20
98
2.13
2.38
12.8
5.1
mmol/l
25.5
25.2
0.11
20
98
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
15
65
2.39
2.36
3.5
2.2
u/l
2213.9
169.4
—
6
22
(3023520) Reticulocytes [#/volume] in Blood
28
157
1.88
2.32
2.0
2.7
e9/l
61.8
70.2
0.86
23
123
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
29
165
1.85
2.30
2.3
3.3
ng/l
209.5
181.5
0.13
24
154
(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay
6
13
4.69
2.28
1.2
2.2
u/ml
40.5
9.3
—
6
13
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
35
212
1.75
2.27
2.8
1.9
u/l
28.2
35.5
0.70
27
178
(3027945) Reticulocytes/100 erythrocytes in Blood
35
212
1.75
2.27
2.9
2.3
%
1.7
1.7
0.03
30
189
(3013512) EKG study
85
639
1.49
2.27
3.5
3.6
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
39
244
1.70
2.26
4.0
2.3
%
23.5
23.2
0.06
33
201
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
121
975
1.44
2.25
2.0
2.0
pmol/l
103.1
100.1
0.18
52
440
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
9
29
3.18
2.24
1.7
1.3
—
—
—
0
0
(3045424) Erythrocytes [Presence] in Urine
10
36
2.85
2.22
1.2
1.5
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
5
9
5.64
2.22
1.4
1.8
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
11
42
2.69
2.21
3.8
1.9
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
34
206
1.75
2.21
1.7
1.4
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
28
160
1.84
2.20
4.8
6.0
%
93.8
95.5
0.42
28
154
(3009542) Hematocrit [Volume Fraction] of Blood
226
2065
1.63
2.14
18.2
12.8
%
38.1
39.7
1.46
161
1508
(3004616) Nuclear Ab [Presence] in Serum
10
37
2.77
2.13
1.5
1.2
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
127
1041
1.42
2.12
2.2
2.4
nmol/l
85.2
79.0
1.41
110
928
(3027008) Opiates [Presence] in Urine
15
69
2.24
2.09
6.1
1.5
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
7
20
3.57
2.07
1.0
1.1
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
46
308
1.60
2.06
2.0
1.5
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
27
156
1.81
2.06
3.0
4.0
%
0.7
0.4
0.30
13
26
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
23
126
1.90
2.06
2.0
1.4
u/ml
72.7
27.1
0.42
23
118
(3035320) C reactive protein [Mass/volume] in Body fluid
6
15
4.07
2.05
1.8
2.5
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
6
15
4.07
2.05
1.0
1.0
—
—
—
0
0
(40768441) Liver Pathology biopsy report
6
15
4.07
2.05
1.3
1.1
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
11
44
2.56
2.04
1.5
1.4
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
8
26
3.14
2.03
1.3
1.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
15
70
2.21
2.02
6.1
1.5
—
—
—
0
0
(40761535) Cells panel - Urine sediment
28
165
1.78
2.00
3.5
2.9
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
47
320
1.57
1.97
3.5
2.7
e6/l
3.4
4.0
0.19
32
152
(3021901) Oxygen saturation in Capillary blood
9
33
2.79
1.95
4.9
2.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
10
39
2.63
1.94
8.5
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
10
39
2.63
1.94
1.5
2.8
u/ml
0.3
0.4
—
5
24
(3019309) Folate [Moles/volume] in Red Blood Cells
59
424
1.50
1.94
1.6
1.7
nmol/l
1148.3
1156.4
0.02
45
315
(3016879) Cocaine [Presence] in Urine
14
65
2.22
1.91
6.4
1.5
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
7
22
3.24
1.89
1.1
1.0
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
25
145
1.80
1.89
2.1
1.7
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
23
130
1.84
1.88
1.5
1.3
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
74
560
1.45
1.88
1.3
1.5
nmol/l
25.3
22.7
0.54
63
474
(3030905) Polymorphonuclear cells [#/volume] in Blood
10
40
2.56
1.86
5.4
2.9
e9/l
3.1
4.5
—
10
40
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
10
40
2.56
1.86
5.7
3.5
%
54.9
57.9
—
10
40
(4281824)
6
17
3.59
1.85
1.0
1.0
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
55
394
1.50
1.83
3.8
1.9
mmol/l
2.5
2.4
1.08
48
343
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
37
242
1.61
1.83
2.3
1.8
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
5
12
4.22
1.83
1.0
1.1
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
5
12
4.22
1.83
4.4
4.3
—
—
—
0
0
(3028679) Herpes simplex virus Ab [Presence] in Serum
5
12
4.22
1.83
1.0
1.5
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
7
23
3.10
1.81
1.0
1.1
—
—
—
0
0
(3014007) Fractional oxyhemoglobin in Arterial blood
17
88
2.00
1.79
5.9
7.4
%
91.9
93.5
0.55
17
88
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
100
805
1.39
1.78
3.8
3.5
ng/l
20.3
22.8
0.22
64
507
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
238
2225
1.66
1.78
4.3
3.9
mmol/l
1.3
1.3
0.69
218
2045
(3022948) Iron [Moles/volume] in Serum or Plasma
44
304
1.54
1.73
3.7
2.1
umol/l
12.8
14.2
0.53
38
274
(3022621) pH of Urine by Test strip
26
157
1.73
1.73
4.3
2.8
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
5
13
3.90
1.72
1.6
1.4
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
5
13
3.90
1.72
1.0
1.5
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
5
13
3.90
1.72
2.0
1.4
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
12
55
2.24
1.70
1.3
1.1
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
14
69
2.09
1.68
6.6
1.5
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
71
544
1.42
1.67
2.8
2.2
mg/l
3.5
3.0
0.68
55
456
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
19
3.21
1.67
1.0
1.4
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
233
2175
1.57
1.66
6.4
5.5
mmol/mol
39.1
39.2
0.06
220
2040
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
20
113
1.83
1.65
1.8
1.6
—
—
—
0
0
(3000492) Spirometry study
31
200
1.62
1.63
1.4
1.4
—
—
—
0
0
(4211845)
5
14
3.62
1.62
4.4
3.9
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
5
14
3.62
1.62
2.4
1.5
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
7
26
2.74
1.59
1.9
1.5
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
26
163
1.66
1.53
4.9
2.9
mmol/l
1.7
2.4
0.56
21
141
(3026493) Urate [Moles/volume] in Serum or Plasma
69
534
1.39
1.53
2.8
2.1
umol/l
16143.3
8411.2
0.29
63
460
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
5
15
3.38
1.53
2.8
1.9
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
12
58
2.12
1.51
1.2
1.2
—
—
—
0
0
(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method
6
21
2.90
1.51
2.2
1.8
—
14.7
—
0
5
(3048689) Calprotectin [Mass/mass] in Stool
43
307
1.48
1.46
2.0
2.0
ug/g
374.0
93.2
0.60
25
237
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
31
206
1.57
1.46
3.8
2.8
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
6
22
2.77
1.44
1.8
1.6
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
24
150
1.66
1.44
3.3
4.1
%
0.0
0.0
0.49
12
25
(40761536) Microorganisms panel - Urine sediment
28
183
1.59
1.41
5.4
3.3
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
9
40
2.29
1.41
23.3
2.4
kpa
5.2
5.0
—
9
40
(3027315) Oxygen [Partial pressure] in Blood
9
40
2.29
1.41
23.3
2.4
kpa
8.7
8.5
—
9
40
(3000570) Elastase.pancreatic [Mass/mass] in Stool
13
67
1.99
1.41
1.2
1.3
ug/g
379.1
314.8
—
7
35
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
7
29
2.45
1.40
1.7
1.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
32
217
1.54
1.39
2.3
1.8
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
9
41
2.24
1.38
1.3
1.3
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
9
41
2.24
1.38
1.6
1.5
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
6
23
2.64
1.37
3.0
1.9
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
63
489
1.38
1.37
5.1
3.9
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
20
121
1.71
1.35
1.4
1.4
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
54
2.08
1.35
1.4
1.1
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
38
270
1.48
1.33
10.1
6.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
11
55
2.04
1.29
7.7
1.5
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
49
368
1.41
1.29
2.5
1.8
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
14
77
1.86
1.28
1.4
1.4
miu/ml
391.3
277.3
—
6
40
(3027944) Amphetamines [Presence] in Urine
13
70
1.90
1.26
7.1
1.5
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
236
2236
1.49
1.25
6.5
5.4
mu/l
1.7
2.4
0.75
220
2066
(3021788) Differential panel - Synovial fluid
9
45
2.03
1.24
2.4
1.6
—
—
—
0
0
(3010421) pH of Blood
10
49
2.08
1.23
21.5
2.2
ph
7.4
7.4
—
10
40
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
8
37
2.20
1.22
1.8
1.6
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
5
19
2.66
1.22
2.0
1.6
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
5
19
2.66
1.22
1.0
1.2
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
23
149
1.60
1.22
3.3
4.1
%
0.0
3.6
—
10
24
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
15
86
1.79
1.21
1.1
1.2
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
8
38
2.14
1.19
2.1
1.2
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
8
38
2.14
1.19
2.1
1.2
—
—
—
0
0
(3020891) Body temperature
11
57
1.97
1.18
12.5
4.7
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
15
87
1.77
1.17
1.1
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
15
88
1.75
1.14
1.1
1.2
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
31
220
1.46
1.11
2.2
1.7
—
—
—
0
0
(44790048)
5
21
2.41
1.09
2.0
1.6
—
—
—
0
0
(44790049)
5
21
2.41
1.09
2.0
1.6
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
5
21
2.41
1.09
1.0
1.3
—
—
—
0
0
(44790047)
5
21
2.41
1.09
2.0
1.6
—
—
—
0
0
(44806118)
5
21
2.41
1.09
2.0
1.6
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
21
138
1.57
1.06
1.2
1.3
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
122
1071
1.26
1.06
3.1
2.8
ug/l
106.4
79.5
0.98
107
989
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
5
22
2.30
1.04
2.0
1.0
—
—
—
0
0
(3008898) HLA-B27 [Presence]
5
108
0.45
1.03
1.0
1.1
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
7
35
2.03
1.00
6.3
2.0
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
246
2368
1.52
0.99
5.6
5.0
mmol/l
2.7
2.8
2.04
225
2193
(3025468) Yersinia sp identified in Specimen by Organism specific culture
5
23
2.20
0.98
2.0
1.0
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
5
23
2.20
0.98
2.0
1.0
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
5
23
2.20
0.98
4.8
3.5
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
9
50
1.83
0.97
1.2
1.1
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
22
150
1.51
0.96
3.3
4.0
%
0.0
0.3
—
9
23
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
10
55
1.85
0.93
2.0
1.8
ug/l
172.3
172.2
—
10
49
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
10
55
1.85
0.93
2.2
2.0
%
100.8
98.3
—
10
50
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
24
169
1.46
0.91
7.2
2.3
mmol/l
1.2
1.2
0.52
19
145
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
6
29
2.09
0.90
1.5
1.1
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
6
29
2.09
0.90
1.0
1.4
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
240
2308
1.41
0.88
5.6
4.5
mmol/l
5.9
5.8
0.27
222
2124
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
58
476
1.28
0.87
1.8
1.7
pmol/l
436.9
458.2
0.15
48
390
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
15
97
1.58
0.83
3.2
1.9
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
161
1484
1.22
0.81
3.3
3.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
101
890
1.22
0.80
4.7
3.7
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
24
175
1.41
0.78
2.0
1.8
ml/min/173m2
53.9
70.5
—
7
65
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
5
24
2.10
0.75
2.0
1.0
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
5
24
2.10
0.75
2.0
1.0
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
5
24
2.10
0.75
2.0
1.0
—
—
—
0
0
(4268621)
5
24
2.10
0.75
2.0
2.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
13
84
1.58
0.73
6.7
6.5
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
9
56
1.63
0.73
2.1
1.2
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
5
26
1.94
0.71
1.0
1.3
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
10
61
1.66
0.69
3.1
1.3
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
11
69
1.62
0.69
1.6
1.8
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
9
59
1.54
0.69
2.0
2.0
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
18
128
1.44
0.67
1.6
1.3
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
18
128
1.44
0.67
1.1
1.0
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
28
216
1.33
0.67
1.8
1.6
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
8
50
1.62
0.62
1.3
1.4
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
5
30
1.68
0.61
1.0
1.1
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
11
73
1.53
0.57
1.2
2.0
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
6
37
1.64
0.56
1.2
1.1
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
6
39
1.55
0.53
1.0
1.1
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
6
40
1.51
0.52
2.5
1.6
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
6
40
1.51
0.52
1.0
1.4
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
42
355
1.22
0.51
1.6
1.4
titre
800.0
613.6
0.20
14
97
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
238
2318
1.25
0.49
4.9
4.4
mmol/l
1.6
1.6
0.53
220
2151
(21494755) Public health laboratory ask at order entry panel
16
210
0.75
0.48
1.4
1.3
—
—
—
0
0
(3037121) Protein [Mass/volume] in Urine
10
69
1.47
0.45
1.4
2.7
g/l
0.1
0.3
—
5
15
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
13
95
1.39
0.44
1.5
1.7
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
239
2335
1.23
0.43
5.1
4.4
mmol/l
4.7
4.8
1.18
222
2175
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
11
150
0.72
0.42
1.1
1.4
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
15
114
1.33
0.41
1.3
1.4
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
15
0.00
0.41
0.0
1.6
—
10.9
—
0
15
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
2.3
—
3.3
—
0
15
(3023410) Appearance of Cerebral spinal fluid
5
34
1.48
0.40
1.0
2.2
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
64
576
1.15
0.39
1.4
1.3
u/ml
0.8
2.2
—
8
156
(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma
0
19
0.00
0.39
0.0
1.1
—
34.4
—
0
5
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
5
36
1.40
0.38
1.2
1.2
—
—
—
0
0
(4094501)
9
68
1.33
0.38
1.1
1.0
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
9
69
1.31
0.37
1.4
1.3
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
5
37
1.36
0.37
1.0
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
78
847
0.89
0.36
2.9
2.9
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
57
513
1.14
0.35
5.3
3.8
kg/l
1.0
1.0
—
9
75
(3005322) IgE [Units/volume] in Serum or Plasma
12
154
0.77
0.33
1.2
1.2
u/ml
70.6
208.5
1.90
12
143
(3004588) Protein electrophoresis panel - Serum or Plasma
18
147
1.24
0.31
1.3
1.4
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
7
52
1.36
0.31
1.1
1.1
—
—
—
0
0
(4010399)
21
175
1.22
0.31
1.7
1.5
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
44
491
0.88
0.31
1.4
1.3
u/ml
2.5
12.3
2.78
15
183
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
14
111
1.28
0.30
1.2
1.5
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
8
63
1.28
0.28
2.0
1.7
—
0.4
—
0
6
(3047181) Lactate [Moles/volume] in Blood
8
63
1.28
0.28
3.3
5.1
mmol/l
1.6
1.3
—
8
58
(4034850)
9
72
1.26
0.26
16.9
7.1
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
39
353
1.12
0.23
1.1
1.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
18
209
0.85
0.22
1.7
1.7
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
18
154
1.18
0.21
2.0
1.9
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
5
42
1.19
0.21
1.6
1.3
—
—
—
0
0
(3000012) Reticulocyte production index
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum
0
11
0.00
0.21
0.0
1.3
—
9.3
—
0
11
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
(3006653) Thiamine [Moles/volume] in Blood
0
10
0.00
0.21
0.0
1.6
—
147.0
—
0
10
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
(3024263) Appearance of Synovial fluid
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
(3020874) Milk IgE Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.1
—
0.3
—
0
5
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
6
49
1.23
0.20
2.2
1.1
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
12
99
1.22
0.20
1.8
2.2
e6/l
0.1
0.2
0.28
12
92
(3005033) Fetal Nuchal fold Thickness US
6
51
1.18
0.19
1.3
1.4
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
6
51
1.18
0.19
1.3
1.4
—
—
—
0
0
(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
81
1.24
0.19
1.4
1.3
g/l
2.7
3.0
—
5
69
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
8
70
1.15
0.16
1.5
1.2
mg/l
560.9
384.3
—
8
63
(3041096) Erythrocytes [Presence] in Urine by Automated
69
655
1.07
0.16
4.1
3.3
—
—
—
0
0
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
9
79
1.14
0.15
1.4
1.7
—
206.7
—
0
6
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
9
81
1.11
0.15
8.1
2.8
%
50.9
48.0
—
9
81
(3003327) Ova and parasites identified in Stool by Light microscopy
9
83
1.09
0.15
1.8
1.8
—
—
—
0
0
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
84
1.20
0.14
1.4
1.3
g/l
6.9
10.1
—
5
75
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
14
122
1.16
0.14
1.1
1.0
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
9
106
0.84
0.13
1.4
1.5
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
23
210
1.10
0.12
1.4
1.2
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
52
494
1.07
0.12
1.4
1.3
iu/ml
23.3
37.9
0.69
12
164
(1002224) Polysomnography panel
12
105
1.15
0.11
1.2
1.1
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
72
695
1.05
0.10
1.9
1.6
mmol/l
1.5
1.4
0.70
63
597
(3024928) Oxygen saturation in Venous blood
5
44
1.14
0.10
1.4
2.2
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
87
1.16
0.09
1.4
1.3
—
—
—
0
0
(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
87
1.16
0.09
1.4
1.3
g/l
8.0
7.6
—
5
69
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
87
1.16
0.09
1.4
1.3
g/l
3.7
3.7
—
5
69
(3043238) Trisomy 21 risk [Likelihood] in Fetus
6
54
1.11
0.09
1.7
1.6
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
6
55
1.09
0.09
1.7
1.8
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
25
267
0.93
0.08
1.8
1.8
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
19
175
1.09
0.08
1.5
1.4
—
49.4
—
0
8
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
7
64
1.10
0.08
1.7
1.6
—
—
—
0
0
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
6
75
0.80
0.07
1.7
1.2
—
67.0
—
0
9
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
8
92
0.87
0.07
4.4
2.0
%
1.5
1.0
—
8
92
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
23
217
1.07
0.06
1.0
1.2
iu/ml
123.9
130.4
—
5
95
(3003338) MCHC [Mass/volume]
196
1945
1.03
0.05
23.9
14.9
g/l
330.8
330.8
0.04
196
1934
(3000330) Specific gravity of Urine by Test strip
12
118
1.02
0.00
1.8
3.7
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
13
128
1.02
0.00
2.5
2.5
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
18
185
0.97
0.00
1.1
1.2
—
—
—
0
0
(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3000213) Normetanephrine [Moles/time] in 24 hour Urine
0
6
0.00
0.00
0.0
1.3
—
1.5
—
0
6
(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
6
60
1.00
0.00
1.3
1.4
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035544) Cardiolipin IgG Ab [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3013247) Albumin in CSF/Albumin in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
5.0
—
0
5
(3048879) Bone marrow aspiration report
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3013637) Mi-2 Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000285) Sodium [Moles/volume] in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
101.2
—
0
5
(3020044) Glucose [Moles/volume] in Cerebral spinal fluid
6
63
0.95
0.00
1.7
1.1
mmol/l
3.9
3.7
—
6
57
(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
6
60
1.00
0.00
1.3
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
6
60
1.00
0.00
1.3
1.4
—
—
—
0
0
(43055514) Macroprolactin [Presence] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006441) Cardiolipin IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3027231) Wheat IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014038) Collagen crosslinked N-telopeptide [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3011436) Histone Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
6
60
1.00
0.00
1.3
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_INSITU_VULVA_EXALLC and mortality.

Females

Parameter HR [95% CI] p-value
CD2_INSITU_VULVA_EXALLC 1.318 [1.01, 1.73] 0.045
Birth year 0.995 [0.99, 1.0] 0.251

During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 377 females with CD2_INSITU_VULVA_EXALLC died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_INSITU_VULVA_EXALLC.

N-year risk Females Males
1 0.11% No data
5 0.698% No data
10 1.909% No data
15 3.734% No data
20 6.473% No data

Relationships between endpoints

Index endpoint: CD2_INSITU_VULVA_EXALLC – Carcinoma in situ of vulva

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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