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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of trachea

CD2_INSITU_TRACHEA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

  • not C3_TRACHEA
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D02.1&
  • Hospital discharge: ICD-9 2311
  • Cause of death: ICD-10 D02.1&
  • Cause of death: ICD-9 2311
  • Cancer registry: Topography ICD-O-3 C33
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D02
Name in latin
Carcinoma in situ cutis

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 5 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 59.41 - -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(36304419) Bacteria [Presence] in Urine
5
14
+∞
2.48
1.0
3.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
5
15
+∞
2.35
1.0
4.7
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
5
31
+∞
0.82
2.4
3.5
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
5
36
+∞
0.50
25.4
15.3
%
14.8
13.5
—
5
36
(1761868) Lipid panel - Serum or Plasma
0
11
0.00
0.24
0.0
4.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
0
11
0.00
0.24
0.0
1.1
—
—
—
0
0
(3044889) 12 lead EKG panel
5
38
+∞
0.24
3.2
4.1
—
—
—
0
0
(3013512) EKG study
0
12
0.00
0.24
0.0
2.9
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
5
41
+∞
0.24
16.2
12.8
ml/min/173m2
71.2
71.0
—
5
29
(3000494) Fungus identified in Specimen by Culture
0
9
0.00
0.24
0.0
1.9
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
0
9
0.00
0.24
0.0
1.1
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
5
43
+∞
0.00
15.6
11.3
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
14.0
—
1.1
—
0
5
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3019225) pH of Specimen
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
103.2
—
0
6
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3022621) pH of Urine by Test strip
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3012544) pH of Venous blood
0
7
0.00
0.00
0.0
6.9
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
0
6
0.00
0.00
0.0
7.8
—
5.9
—
0
6
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
2.0
—
0
5
(3002032) Base excess in Venous blood by calculation
0
6
0.00
0.00
0.0
7.8
—
-0.2
—
0
6
(3000991) Gas panel - Venous blood
0
6
0.00
0.00
0.0
8.2
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
5
45
+∞
-0.00
15.8
15.9
umol/l
82.0
83.8
—
5
45

Mortality – FinRegistry

Association

Association between endpoint CD2_INSITU_TRACHEA_EXALLC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_INSITU_TRACHEA_EXALLC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: CD2_INSITU_TRACHEA_EXALLC – Carcinoma in situ of trachea

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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