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Carcinoma in situ, thyroid and other endocrine glands

CD2_INSITU_THYROICD2_ENDOCRINE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D09.3&
  • Cause of death: ICD-10 D09.3&

2 out of 7 registries used, show all original rules.

11

4. Check minimum number of events

None

11

5. Include endpoints

None

11

6. Filter based on genotype QC (FinnGen only)

11

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D09
Name in latin
Carcinoma in situ glandulae thyreoideae

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 11 9 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 46.66 44.82 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3018418) pH of Serum or Plasma
6
25
4.02
1.50
4.3
5.2
—
7.4
—
0
5
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
11
77
+∞
1.47
8.5
4.1
pmol/l
17.9
15.2
3.92
11
69
(42870588) Differential panel, method unspecified - Blood
6
29
3.31
1.12
3.5
3.1
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
0
25
0.00
0.93
0.0
1.8
—
633.0
—
0
19
(3026493) Urate [Moles/volume] in Serum or Plasma
0
27
0.00
0.92
0.0
2.4
—
14990.5
—
0
22
(3029937) Albumin [Presence] in Urine by Test strip
0
27
0.00
0.92
0.0
5.7
—
0.0
—
0
10
(3013826) Glucose [Moles/volume] in Serum or Plasma
5
65
0.58
0.28
4.8
3.6
mmol/l
5.9
7.0
—
5
60
(3022145) Colonoscopy Study observation
0
10
0.00
0.22
0.0
1.7
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
10
0.00
0.22
0.0
2.5
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
10
0.00
0.22
0.0
1.5
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
11
97
+∞
0.22
9.5
4.8
mu/l
0.7
1.9
4.88
11
83
(3044889) 12 lead EKG panel
6
66
0.80
0.12
2.7
2.6
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
3.6
—
1.2
—
0
5
(3038515) Glucose [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
3.6
—
6.0
—
0
5
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
0
5
0.00
0.00
0.0
4.6
—
0.7
—
0
5
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.6
—
26.1
—
0
5
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
0
5
0.00
0.00
0.0
4.6
—
0.7
—
0
5
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
0
5
0.00
0.00
0.0
4.8
—
49.7
—
0
5
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
0.3
—
0
5
(3023323) Follitropin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
29.4
—
0
5
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
11
101
+∞
0.00
16.5
19.8
umol/l
67.8
69.0
0.14
11
101
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
5
49
1.04
0.00
4.2
5.0
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
5
0.00
0.00
0.0
8.8
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
3.3
—
1.6
—
0
6
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
0
6
0.00
0.00
0.0
3.0
—
1.1
—
0
6
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
0
6
0.00
0.00
0.0
3.0
—
0.5
—
0
6
(3036481) Cortisol [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.0
—
541.2
—
0
6
(3027273) Bicarbonate [Moles/volume] in Venous blood
0
6
0.00
0.00
0.0
3.5
—
23.3
—
0
6
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
6.1
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
5
55
0.83
0.00
1.4
2.1
nmol/l
59.0
80.7
—
5
48
(3019832) Treponema pallidum Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
8
0.00
0.00
0.0
4.5
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
0
8
0.00
0.00
0.0
6.5
—
1.2
—
0
8
(3004119) Hemoglobin [Mass/volume] in Venous blood
0
7
0.00
0.00
0.0
4.3
—
129.1
—
0
7
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_THYROICD2_ENDOCRINE – Carcinoma in situ, thyroid and other endocrine glands

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).