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Carcinoma in situ of penis

Endpoint Browser PheWeb

CD2_INSITU_PENIS_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only males

-

2. Check conditions

  • not C3_PENIS
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D07.4&
  • Hospital discharge: ICD-9 — 2335
  • Cause of death: ICD-10 — D07.4&
  • Cause of death: ICD-9 — 2335
  • Cancer registry: Topography ICD-O-3 — C60
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D07
Name in latin
Carcinoma in situ vesicae urinariae

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 54 - 54
Unadjusted period prevalence (%) 0.02 - 0.02
Median age at first event (years) 66.19 - 66.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(40768443) Skin Pathology biopsy report
15
15
13.46
13.77
1.6
1.2
—
—
—
0
0
(4035726)
13
14
11.91
11.23
1.7
1.1
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
31
95
6.31
10.53
3.6
1.4
—
—
—
0
0
(3002256) Pathology report gross observation
15
27
7.31
8.57
1.5
1.1
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
29
126
3.81
5.55
13.2
5.5
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
20
68
4.08
5.42
1.7
2.5
—
—
—
0
0
(40758558) Short blood count panel - Blood
21
81
3.61
4.67
14.1
5.2
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
7
6
13.13
4.41
1.6
1.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
15
49
3.85
4.19
1.3
1.9
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
10
24
4.89
4.08
2.0
1.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
28
147
2.88
3.55
4.9
4.8
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
22
102
2.95
3.48
3.8
2.5
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
22
104
2.88
3.34
4.5
2.3
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
7
11
7.12
3.30
3.0
1.5
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
17
70
3.08
3.28
4.0
2.5
e6/l
0.8
0.9
0.08
12
41
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
17
70
3.08
3.28
3.9
2.4
e6/l
0.2
0.9
2.06
11
41
(3006315) Basophils [#/volume] in Blood
33
197
2.74
3.17
9.6
5.2
e9/l
0.0
0.0
0.24
27
171
(3001604) Monocytes [#/volume] in Blood
33
197
2.74
3.17
9.6
5.2
e9/l
0.7
0.6
0.54
27
170
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
10
30
3.86
3.08
2.3
1.5
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
33
203
2.61
2.89
10.8
5.3
e9/l
0.2
0.2
0.16
28
176
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
16
69
2.87
2.81
3.0
1.7
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
7
15
5.19
2.69
1.7
4.5
—
—
—
0
0
(3022948) Iron [Moles/volume] in Serum or Plasma
15
64
2.86
2.68
3.4
2.8
umol/l
14.7
12.1
0.55
15
59
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
17
78
2.72
2.66
4.2
2.5
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
26
148
2.46
2.62
5.0
2.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
12
46
3.07
2.56
1.4
1.8
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
24
133
2.45
2.55
7.5
4.1
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
13
55
2.80
2.34
3.7
2.9
%
28.7
24.5
0.32
13
47
(3021589) Normoblasts [#/volume] in Blood
29
181
2.30
2.30
12.9
8.8
e9/l
0.0
0.0
0.00
23
146
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
28
180
2.15
1.99
2.4
1.9
pmol/l
95.6
86.0
0.36
16
106
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
5
12
4.47
1.86
1.2
1.3
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
5
12
4.47
1.86
1.0
1.3
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
7
24
3.19
1.79
2.4
2.0
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
41
316
2.24
1.72
15.1
5.4
u/l
89.4
71.8
1.38
36
292
(3000492) Spirometry study
10
43
2.63
1.72
2.3
1.4
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
28
189
2.00
1.67
3.8
4.1
ng/l
34.3
53.7
0.52
21
145
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
5
14
3.82
1.65
3.6
1.6
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
11
52
2.40
1.57
2.1
1.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
5
15
3.56
1.56
4.8
1.7
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
8
149
0.46
1.29
3.1
3.4
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
14
80
2.01
1.28
2.7
1.9
e6/l
4.6
2.7
0.43
14
62
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
10
50
2.23
1.26
2.2
1.6
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
34
261
1.82
1.25
6.6
3.6
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
43
356
2.02
1.23
37.5
15.8
%
40.5
41.2
0.31
33
236
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
16
98
1.90
1.20
3.1
3.6
ng/l
31.9
250.6
1.37
11
82
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
7
32
2.36
1.13
2.0
1.4
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
45
385
2.01
1.11
27.9
12.3
ml/min/173m2
78.5
76.5
0.23
37
310
(40768797) Stomach Pathology biopsy report
9
47
2.09
1.09
1.3
1.1
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
11
61
2.01
1.08
1.7
1.2
g/l
2.1
2.6
—
5
35
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
22
2.40
1.05
8.6
41.5
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
5
22
2.40
1.05
3.0
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
15
94
1.82
1.04
1.2
1.3
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
7
35
2.15
1.04
3.7
1.6
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
7
36
2.08
1.01
4.1
3.7
—
—
—
0
0
(3022145) Colonoscopy Study observation
7
36
2.08
1.01
1.7
1.2
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
28
0.00
1.01
0.0
1.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
29
223
1.65
0.97
3.3
2.3
—
—
—
0
0
(3009343) pH of Capillary blood
6
28
2.28
0.95
9.2
4.0
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
47
417
1.98
0.92
33.4
13.9
mg/l
40.0
27.5
0.74
40
328
(3007853) Bacteria identified in Skin by Aerobe culture
8
47
1.82
0.85
1.5
2.2
—
—
—
0
0
(3000991) Gas panel - Venous blood
8
47
1.82
0.85
9.1
11.1
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
39
331
1.64
0.82
5.7
3.9
ug/l
3.7
2.1
0.30
33
294
(4034850)
0
26
0.00
0.81
0.0
16.6
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
14
93
1.68
0.79
4.6
2.9
—
—
—
0
0
(3022313) Gas panel - Capillary blood
5
23
2.29
0.78
9.6
3.7
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
5
26
2.01
0.72
1.2
1.9
—
—
—
0
0
(3050449) Albumin [Mass/time] in Urine collected for unspecified duration
0
20
0.00
0.62
0.0
2.0
—
106.6
—
0
12
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
6
34
1.86
0.61
1.8
1.6
—
—
—
0
0
(4010399)
6
37
1.70
0.58
1.0
1.3
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
9
63
1.51
0.56
1.3
1.2
—
0.9
—
0
18
(3044889) 12 lead EKG panel
35
308
1.39
0.47
4.6
4.4
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
8
57
1.47
0.45
6.8
19.6
mmol/l
-0.3
1.0
—
8
39
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
5
34
1.52
0.41
2.6
2.2
—
61.4
—
0
12
(3032080) INR in Blood by Coagulation assay
22
183
1.34
0.41
9.2
11.9
inr
1.5
1.4
—
6
47
(3026008) Bacteria identified in Urine by Culture
13
99
1.41
0.40
3.6
2.5
—
—
—
0
0
(40761535) Cells panel - Urine sediment
6
41
1.52
0.37
8.2
2.5
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
7
53
1.37
0.32
1.9
2.0
%
1.5
2.0
—
7
44
(3019225) pH of Specimen
5
39
1.31
0.23
8.4
3.5
—
—
—
0
0
(3012501) Base excess in Blood by calculation
0
11
0.00
0.21
0.0
2.8
—
2.6
—
0
5
(3038515) Glucose [Moles/volume] in Venous blood
0
12
0.00
0.21
0.0
4.4
—
7.3
—
0
12
(3008037) Lactate [Moles/volume] in Venous blood
0
13
0.00
0.21
0.0
4.2
—
2.0
—
0
13
(4094501)
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
28
259
1.17
0.16
4.2
3.5
%
16.6
24.8
1.88
13
115
(40761511) CBC panel - Blood by Automated count
45
436
1.19
0.14
25.8
13.5
—
—
—
0
0
(3015736) pH of Urine
17
154
1.15
0.12
4.2
3.0
—
—
—
0
0
(3013512) EKG study
15
140
1.10
0.05
7.1
4.2
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
14
150
0.91
0.05
4.2
3.4
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
10
98
1.03
0.00
2.6
3.3
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
(3018301) Testosterone Free [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
5.3
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
1.8
—
4.1
—
0
8
(3035285) Chloride [Moles/volume] in Venous blood
0
8
0.00
0.00
0.0
1.8
—
105.4
—
0
8
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
7
78
0.88
0.00
5.4
4.3
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
6
66
0.90
0.00
11.3
8.4
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
5
56
0.88
0.00
2.8
2.9
ug/l
2.1
7.3
—
5
49
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
5
49
1.02
0.00
10.0
3.6
mmol/l
0.6
1.6
—
5
37
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_INSITU_PENIS_EXALLC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_INSITU_PENIS_EXALLC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_PENIS_EXALLC – Carcinoma in situ of penis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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