info icon

This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_INSITU_OESOPHAGUS_EXALLC for full statistics.

Carcinoma in situ of oesophagus

CD2_INSITU_OESOPHAGUS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • not C3_OESOPHAGUS
519361

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D00.1&
  • Hospital discharge: ICD-9 2301A
  • Cause of death: ICD-10 D00.1&
  • Cause of death: ICD-9 2301A
  • Cancer registry: Topography ICD-O-3 C15
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

41

4. Check minimum number of events

None

41

5. Include endpoints

None

41

6. Filter based on genotype QC (FinnGen only)

41

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D00
Name in latin
Carcinoma in situ coli

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 41 8 33
Unadjusted period prevalence (%) 0.01 0.00 0.01
Median age at first event (years) 69.25 70.95 68.83

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(40768797) Stomach Pathology biopsy report
23
34
14.13
16.86
3.7
1.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
32
150
6.14
6.40
8.3
4.4
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
23
88
4.68
5.62
4.0
2.6
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
27
121
4.61
5.27
4.0
2.6
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
14
41
4.67
4.68
11.6
11.8
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
28
156
3.51
3.48
2.4
2.0
pmol/l
98.2
88.3
0.48
18
83
(40768804) Tissue Pathology biopsy report
24
126
3.18
3.22
3.7
2.1
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
13
49
3.42
2.96
5.7
4.5
%
31.0
29.3
—
7
31
(3022313) Gas panel - Capillary blood
8
21
4.47
2.62
5.6
3.6
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
31
205
3.10
2.52
7.2
4.4
mmol/l
7.1
6.8
0.30
31
195
(3020961) Endomysium IgA Ab [Titer] in Serum
5
8
6.92
2.44
1.0
1.1
—
—
—
0
0
(3019060) Gas panel - Arterial blood
9
30
3.55
2.32
4.0
3.2
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
24
145
2.58
2.23
11.0
4.8
g/l
34.2
34.8
0.23
24
140
(36660697) Celiac disease serology panel - Serum
7
20
4.00
2.16
1.9
1.2
—
—
—
0
0
(3020891) Body temperature
6
15
4.49
2.12
5.8
3.6
—
—
—
0
0
(3019225) pH of Specimen
10
39
3.07
2.10
3.2
5.8
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
19
106
2.48
2.05
3.1
3.5
mg/l
2932.6
84.7
0.46
13
70
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
6
16
4.20
2.01
3.2
1.4
ug/l
390.3
470.9
—
6
16
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
8
28
3.29
1.98
1.5
3.4
umol/l
7.3
11.5
—
8
22
(3022145) Colonoscopy Study observation
7
22
3.61
1.98
1.7
1.3
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
19
109
2.38
1.90
6.9
5.5
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
12
4.58
1.88
1.4
1.4
—
—
—
0
0
(40761535) Cells panel - Urine sediment
8
31
2.95
1.77
2.5
4.0
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
7
25
3.16
1.74
1.3
1.5
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
20
3.33
1.65
7.2
8.5
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
19
115
2.22
1.63
3.4
4.4
mg/mmol
2.1
11.7
1.68
13
77
(3002256) Pathology report gross observation
10
46
2.55
1.54
1.4
1.3
—
—
—
0
0
(3012095) Magnesium [Moles/volume] in Serum or Plasma
13
69
2.29
1.49
3.8
3.3
mmol/l
0.8
0.8
0.97
13
64
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
0
38
0.00
1.43
0.0
3.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
11
56
2.32
1.37
2.2
1.8
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
7
131
0.44
1.29
2.7
3.1
e6/l
19.4
73.2
—
7
101
(3000330) Specific gravity of Urine by Test strip
5
19
2.85
1.25
1.6
5.9
—
—
—
0
0
(4035726)
7
31
2.51
1.17
1.3
1.5
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
7
31
2.51
1.17
7.3
6.6
%
1.4
1.4
—
7
31
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
7
31
2.51
1.17
7.3
7.4
%
0.9
0.6
—
7
31
(3018095) Leukocytes [#/volume] in Urine
8
136
0.49
1.09
3.0
3.9
e6/l
185.2
22.8
—
8
102
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
34
286
2.10
0.99
5.0
4.1
mu/l
1.9
2.0
0.31
27
251
(36304419) Bacteria [Presence] in Urine
6
108
0.48
0.88
3.7
2.9
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
18
128
1.72
0.86
3.1
4.8
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
6
33
1.95
0.82
1.0
1.9
g/l
64.3
66.7
—
6
28
(3022217) INR in Platelet poor plasma by Coagulation assay
9
55
1.81
0.81
38.2
24.6
—
1.1
—
0
8
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
0
27
0.00
0.80
0.0
2.2
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
27
0.00
0.80
0.0
4.8
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
32
271
1.82
0.79
24.7
18.6
%
34.3
39.5
0.65
14
184
(3007853) Bacteria identified in Skin by Aerobe culture
7
41
1.85
0.74
2.7
2.0
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
36
323
1.94
0.65
28.8
17.4
mg/l
27.3
28.2
0.07
36
266
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
0
19
0.00
0.62
0.0
2.3
—
—
—
0
0
(3020779) Urea [Moles/volume] in Serum or Plasma
6
36
1.78
0.60
4.2
7.6
mmol/l
6.3
10.4
—
6
36
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
34
303
1.71
0.59
8.7
6.9
mmol/mol
43.4
41.1
0.63
29
283
(3000991) Gas panel - Venous blood
6
37
1.73
0.58
8.7
8.8
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
27
228
1.54
0.56
5.1
4.7
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
9
64
1.52
0.56
1.0
1.4
—
—
—
0
0
(3012544) pH of Venous blood
6
40
1.58
0.54
2.3
4.3
—
—
—
0
0
(3013512) EKG study
15
114
1.50
0.50
7.4
4.8
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
14
106
1.49
0.47
3.3
3.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
20
163
1.44
0.47
2.2
2.9
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
8
55
1.56
0.47
5.9
4.8
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
5
32
1.64
0.44
1.6
1.8
nmol/l
415.2
344.6
—
5
27
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
15
117
1.44
0.43
3.6
5.0
—
—
—
0
0
(4010399)
5
33
1.58
0.43
2.2
1.3
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
9
66
1.46
0.42
1.9
2.0
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
15
0.00
0.42
0.0
1.7
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
0
16
0.00
0.42
0.0
1.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
18
0.00
0.41
0.0
1.7
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
5
75
0.62
0.40
2.0
3.3
mmol/l
2.5
2.5
—
5
63
(3011397) Hemoglobin [Presence] in Urine by Test strip
11
82
1.47
0.39
3.8
4.1
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
6
43
1.46
0.37
1.5
1.7
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
6
44
1.42
0.36
1.5
1.8
—
—
—
0
0
(40758558) Short blood count panel - Blood
10
76
1.42
0.32
7.2
7.4
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
11
86
1.38
0.30
2.4
1.7
mmol/l
1.2
1.4
0.26
11
72
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
17
144
1.31
0.28
2.6
3.4
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
5
42
1.22
0.22
1.6
1.6
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
5
42
1.22
0.22
1.2
1.4
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
0
10
0.00
0.21
0.0
3.4
—
—
—
0
0
(4094501)
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
18
159
1.24
0.20
3.9
6.3
—
0.0
—
0
30
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
35
334
1.33
0.17
5.9
5.4
mmol/l
2.3
2.6
0.62
30
302
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
34
324
1.29
0.16
5.7
4.8
mmol/l
4.2
4.4
0.32
28
295
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
34
322
1.33
0.16
6.3
5.0
mmol/l
6.1
6.2
0.07
29
293
(3044889) 12 lead EKG panel
22
238
0.84
0.15
5.6
4.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
7
79
0.86
0.08
2.1
4.6
—
—
—
0
0
(3018418) pH of Serum or Plasma
9
98
0.90
0.07
2.4
4.4
—
7.4
—
0
17
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
18
172
1.08
0.03
4.3
4.5
%
18.8
21.4
—
7
84
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
31
312
0.97
0.00
5.0
4.3
mmol/l
1.3
1.3
0.15
25
283
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
0.00
0.0
1.4
—
197.6
—
0
7
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
0
7
0.00
0.00
0.0
4.0
—
8.5
—
0
7
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
7
69
1.02
0.00
2.6
3.0
ng/l
375.6
110.0
—
7
60
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
0
7
0.00
0.00
0.0
1.6
—
1.5
—
0
7
(3013290) Carbon dioxide [Partial pressure] in Blood
0
7
0.00
0.00
0.0
4.0
—
4.6
—
0
7
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021387) Prolactin [Units/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
264.6
—
0
8
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3020044) Glucose [Moles/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
3.6
—
0
6
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
5
0.00
0.00
0.0
2.4
—
33.0
—
0
5
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
(3040151) Glucose [Moles/volume] in Capillary blood
0
5
0.00
0.00
0.0
3.0
—
8.0
—
0
5
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026179) Normetanephrine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
0.5
—
0
6
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
9
0.00
0.00
0.0
3.6
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3009214) Lutropin [Units/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
5.3
—
0
9
(3019473) Protein [Mass/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.1
—
732.3
—
0
8
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
0
8
0.00
0.00
0.0
2.8
—
66.3
—
0
8
(3035637) Corticotropin [Mass/volume] in Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(1002224) Polysomnography panel
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
33
324
1.09
0.00
5.8
4.7
mmol/l
1.3
1.4
0.64
27
293

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_OESOPHAGUS – Carcinoma in situ of oesophagus

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).