Carcinoma in situ of lip, oral cavity and pharynx

CD2_INSITU_LIPORALPHARYNX_EXALLC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data
1. Apply sex-specific rule None	-
2. Check conditions None
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D00.0 Hospital discharge: ICD-9 — 2300 Cause of death: ICD-10 — D00.0 Cause of death: ICD-9 — 2300 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints None	-
6. Filter based on genotype QC (FinnGen only) None	-

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D00
Name in latin: Carcinoma in situ labii (oris)

NAME	CD2_INSITU_LIPORALPHARYNX_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D000
HD_ICD_9	2300
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D000
COD_ICD_9	2300
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Carcinoma in situ of lip, oral cavity and pharynx based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Carcinoma in situ of lip, oral cavity and pharynx

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	87	29	58
Unadjusted period prevalence (%)	0.02	0.01	0.03
Median age at first event (years)	67.18	69.00	66.26

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
73: Matched controls
729

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

EJA10

NOMESCO Finland

Biopsy of tongue or floor of mouth

98.8

24.8

D00.00

ICD-10 Finland

Cancer in situ on the lip red border

+∞

18.5

130

Kela drug reimbursment

Malignant tumour

+∞

16.2

D00.06

ICD-10 Finland

Cancer in situ in another part of the tongue

+∞

14.0

C02.11

ICD-10 Finland

Malignant neoplasm of border of tongue

+∞

14.0

EP1AE

NOMESCO Finland

Neck ultrasound examination

36.2

13.7

WZC00

NOMESCO Finland

Planning of intervention or health care consultation

7.5

13.4

EKA10

NOMESCO Finland

Biopsy of cheek

61.9

13.4

D00.09

ICD-10 Finland

Unspecified cancer in situ in oral cavity and throat

+∞

12.9

EJB10

NOMESCO Finland

Excision of lesion of apex or body of tongue

77.8

12.0

TEA00

NOMESCO Finland

Biopsy of lip

+∞

11.8

SBB00

NOMESCO Finland

Fotograf of mouth and teeth

17.9

11.7

ECA20

NOMESCO Finland

Biopsy of gingiva

127.6

10.7

EN1BD

NOMESCO Finland

Very extensive CT examination of mouth and soft tissues of neck

+∞

10.7

JDB10

NOMESCO Finland

Percutaneous gastrostomy

+∞

10.7

EJB30

NOMESCO Finland

Excision of lesion of floor of mouth

+∞

10.7

504

Kela drug reimbursment

Conditions requiring daily forced enteral nutrition

63.8

9.9

SBA00

NOMESCO Finland

Microbiological examinations

25.9

9.7

WZC20

NOMESCO Finland

Multidisciplinary treatment meeting

114.2

9.7

K13.28

ICD-10 Finland

Other leukoplakia or disorder of epithelium of the palate or tongue

114.2

9.7

D00.04

ICD-10 Finland

In situ cancer of the floor of the mouth

+∞

9.6

A07AA02

ATC

nystatin; oral

11.7

8.8

C61

ICD-10 Finland

Malignant neoplasm of prostate

+∞

8.5

EP1CG

NOMESCO Finland

Extensive MRI examination of soft tissue of neck with high intesity magnet

+∞

8.5

K13.79

ICD-10 Finland

Change in the oral mucosa UNS

25.5

8.3

A03FA01

ATC

metoclopramide; systemic, rectal

7.6

8.1

EAA10

NOMESCO Finland

Excision of lesion of lip

50.6

7.9

K13.78

ICD-10 Finland

Other change in the oral mucosa

15.6

7.7

JN4BD

NOMESCO Finland

Extensive body CT

11.2

7.7

PJD71

NOMESCO Finland

Extended sparing excision of cervical lymph nodes

+∞

7.4

C03.0

ICD-10 Finland

Malignant neoplasm: Upper gum

+∞

7.4

8140/3-C61.9

ICD-O-3

Adenocarcinoma, NOS, of prostate gland

+∞

7.4

D00.01

ICD-10 Finland

In situ cancer of the mucous membrane of the cheek

+∞

7.4

H02AB02

ATC

dexamethasone; systemic

33.7

7.3

SAA03

NOMESCO Finland

Extended examination of mouth

3.8

6.9

177

K08.1

ICD-10 Finland

Loss of teeth due to accident, extraction or local periodontal disease

5.7

6.9

EP1DG

NOMESCO Finland

Very extensive examination of soft tissue of neck with high intesity magnet

76.2

6.5

N02AA05

ATC

oxycodone; systemic

5.6

6.5

EKB00

NOMESCO Finland

Excision of lesion of cheek

+∞

6.3

C06.0

ICD-10 Finland

Malignant neoplasm: Cheek mucosa

+∞

6.3

WF002

NOMESCO Finland

Radical radiotherapy

+∞

6.3

EDB00

NOMESCO Finland

Partial excision of mandible

+∞

6.3

ZX012

NOMESCO Finland

Radiotherapy with large shaped fields - isocentric therapy

+∞

6.3

EAA30

NOMESCO Finland

Partial excision of lower lip

+∞

6.3

D00.05

ICD-10 Finland

In situ cancer of the pharyngeal part of the tongue

+∞

6.3

C03.1

ICD-10 Finland

Malignant neoplasm: Lower gum

+∞

6.3

WB103

NOMESCO Finland

Simple adjuvant cytostatic therapy

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(4035726)

14.91

19.35

1.6

1.3

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

6.84

13.69

2.8

2.1

g/l

0.2

0.33

(40768804) Tissue Pathology biopsy report

171

4.38

10.64

4.0

1.6

—

(3002256) Pathology report gross observation

6.12

10.41

1.8

1.2

—

(3000991) Gas panel - Venous blood

4.68

6.21

6.4

9.8

—

(3026389) Candida sp identified in Specimen by Organism specific culture

12.35

5.96

3.4

1.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

262

2.99

5.92

5.6

3.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

126

3.11

5.51

3.3

1.9

—

(3044640) Blood type and Crossmatch panel - Blood

172

2.73

4.73

3.7

2.1

—

(3023368) Bacteria identified in Blood by Culture

184

2.63

4.46

7.6

4.3

—

(3003396) Base excess in Arterial blood by calculation

3.14

4.46

6.9

6.5

mmol/l

0.5

1.7

0.73

(3000494) Fungus identified in Specimen by Culture

3.10

4.37

1.9

1.4

—

(3037522) Nuclear Ab [Titer] in Serum

3.10

4.05

1.3

titre

368.0

536.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

104

2.81

4.05

2.8

1.7

—

(3001604) Monocytes [#/volume] in Blood

314

2.39

3.84

7.3

5.1

e9/l

0.6

0.28

260

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

3.65

3.80

7.6

8.3

0.5

0.8

2.07

(3006315) Basophils [#/volume] in Blood

316

2.37

3.76

7.3

5.1

e9/l

0.0

0.07

264

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.21

3.57

2.1

1.4

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

10.61

3.55

1.3

—

(3019198) Lymphocytes [#/volume] in Blood

323

2.29

3.49

7.3

5.2

e9/l

1.8

0.14

273

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

113

2.55

3.41

2.4

2.3

e6/l

0.3

1.0

1.97

(3013115) Eosinophils [#/volume] in Blood

326

2.26

3.38

7.4

5.5

e9/l

0.2

2.31

274

(1761868) Lipid panel - Serum or Plasma

233

0.32

3.37

3.4

3.3

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

3.09

3.35

6.0

6.4

mmol/l

2.2

1.4

0.60

(3042936) Bacteria identified in Isolate by Culture

110

2.48

3.15

2.9

1.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.73

3.14

2.3

1.7

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

3.32

3.11

7.7

8.3

1.2

1.5

0.67

(3044941) Cell count panel - Synovial fluid

7.95

3.10

1.5

1.0

—

(40758558) Short blood count panel - Blood

133

2.36

3.07

10.0

5.3

—

(36304419) Bacteria [Presence] in Urine

172

2.25

3.03

3.6

2.6

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.24

2.99

2.3

1.5

—

(3030467) Casts [#/volume] in Urine by Automated count

181

2.21

2.98

3.6

2.6

e6/l

0.4

0.5

0.09

130

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

2.69

2.95

3.2

2.7

umol/l

19.5

7.5

0.43

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

251

2.10

2.85

2.2

2.3

nmol/l

77.4

75.7

0.15

216

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.08

2.77

1.4

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

6.35

2.74

1.8

1.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

290

2.05

2.71

2.3

2.0

pmol/l

86.0

93.5

0.56

141

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.79

2.69

1.2

1.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.50

2.58

2.1

1.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

233

2.02

2.55

4.0

2.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

351

2.00

2.53

13.3

6.1

e9/l

4.4

4.3

0.06

295

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.19

2.50

9.5

7.7

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

5.28

2.44

1.8

1.3

—

(3002030) Lymphocytes/100 leukocytes in Blood

299

1.95

2.41

6.7

5.5

24.2

26.9

0.90

271

(3018010) Neutrophils/100 leukocytes in Blood

299

1.95

2.41

6.5

5.2

59.9

57.9

0.48

273

(3002582) Erythrocytes [#/volume] in Urine

195

2.01

2.39

3.9

2.8

e6/l

68.9

391.6

0.47

147

(46235355) HIV 1 and 2 tests - Meaningful Use set

2.46

2.38

1.4

1.6

—

(42870588) Differential panel, method unspecified - Blood

205

1.98

2.33

6.5

5.4

—

(3019832) Treponema pallidum Ab [Presence] in Serum

3.34

2.30

1.3

1.9

—

(3018095) Leukocytes [#/volume] in Urine

224

1.94

2.25

3.8

3.4

e6/l

71.7

50.3

0.18

159

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.38

2.13

4.9

2.4

u/l

218.8

235.2

0.42

(40760888) Immunoglobulin light chains.free panel - Serum

5.23

2.10

5.4

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.17

1.84

10.9

8.1

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

3.50

1.78

3.5

1.4

—

(3012544) pH of Venous blood

2.19

1.70

5.1

3.6

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

3.31

1.69

1.8

1.0

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

2.03

1.66

2.6

2.3

15.8

23.3

1.80

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.21

1.64

1.2

1.5

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

3.14

1.61

4.5

1.9

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

3.47

1.54

1.0

1.2

—

(3032080) INR in Blood by Coagulation assay

293

1.68

1.53

7.7

9.7

inr

1.0

1.3

—

(3003694) ABO and Rh group [Type] in Blood

162

1.76

1.48

1.3

—

(3002032) Base excess in Venous blood by calculation

2.11

1.47

5.4

3.6

mmol/l

1.7

2.6

0.30

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

105

1.90

1.47

2.8

2.6

e6/l

1.5

3.0

0.53

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

2.85

1.46

1.0

1.4

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

3.25

1.46

1.6

1.1

—

(3026008) Bacteria identified in Urine by Culture

190

1.70

1.40

4.0

2.7

—

(4010399)

2.27

1.40

1.5

1.3

—

(3022621) pH of Urine by Test strip

2.27

1.38

2.2

2.0

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.22

1.35

1.2

1.4

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

2.49

1.33

1.0

1.1

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.49

1.33

4.1

2.5

2.0

1.2

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.49

1.33

4.1

2.5

0.7

0.6

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

663

1.95

1.32

31.5

13.2

mg/l

40.8

24.4

2.05

508

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.34

1.28

8.0

7.2

mmol/l

23.6

25.7

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.98

1.20

1.3

1.4

—

(3022145) Colonoscopy Study observation

2.03

1.18

1.4

1.2

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

2.03

1.18

2.1

2.0

nmol/l

334.0

384.7

0.32

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.10

1.15

1.3

2.0

—

(3019309) Folate [Moles/volume] in Red Blood Cells

142

1.63

1.05

1.4

1.8

nmol/l

1205.2

1204.4

0.00

111

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

2.35

1.05

2.8

1.5

u/ml

0.2

0.3

—

(3022313) Gas panel - Capillary blood

2.03

0.99

6.7

3.1

—

(3021589) Normoblasts [#/volume] in Blood

292

1.46

0.93

9.4

8.5

e9/l

0.0

0.50

234

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.94

0.83

1.0

1.3

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.77

0.83

6.3

2.1

g/l

10.4

10.7

—

(3037467) Urinalysis macro (dipstick) panel - Urine

426

1.41

0.79

5.6

4.1

—

(3019060) Gas panel - Arterial blood

1.74

0.77

7.1

4.0

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.15

0.76

12.2

4.2

—

(3019225) pH of Specimen

1.68

0.75

11.9

3.0

—

(3012516) Albumin [Mass/volume] in Urine

217

1.43

0.75

4.1

3.4

mg/l

35.5

335.0

0.56

149

(3045414) Leukocytes [Presence] in Urine

2.06

0.74

2.4

1.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

361

1.38

0.72

2.9

2.6

—

(40761535) Cells panel - Urine sediment

1.61

0.72

4.7

3.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

146

1.48

0.72

4.7

3.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

165

0.62

0.72

3.5

3.1

—

(3000330) Specific gravity of Urine by Test strip

1.77

0.72

3.6

2.8

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.83

0.67

2.0

3.1

e6/l

0.3

0.1

—

(3020891) Body temperature

1.77

0.65

6.0

3.8

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

0.00

0.61

0.0

1.5

—

2.6

—

(4094501)

0.00

0.60

0.0

1.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.77

0.59

1.2

1.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

269

1.30

0.50

3.8

3.4

13.3

24.7

5.28

124

(3004588) Protein electrophoresis panel - Serum or Plasma

1.53

0.49

5.9

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

300

1.28

0.47

4.7

3.9

ng/l

21.0

59.6

2.38

231

(3020682) Albumin/Creatinine [Ratio] in Urine

235

1.28

0.44

4.5

4.1

mg/mmol

4.0

9.3

0.99

156

(3013512) EKG study

212

0.75

0.42

6.9

4.0

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

192

1.27

0.37

1.7

2.6

ug/l

0.5

0.8

1.44

127

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.50

0.37

3.0

2.6

—

(3044889) 12 lead EKG panel

468

1.22

0.34

5.2

4.0

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.32

0.29

1.3

1.5

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.67

0.27

4.0

3.2

—

(40761511) CBC panel - Blood by Automated count

694

1.22

0.22

26.9

12.5

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

2.4

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.21

0.0

3.1

—

34.5

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.21

0.0

1.1

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.20

0.0

1.8

—

(3004775) Volume in Urine collected for unspecified duration

0.00

0.20

0.0

2.2

—

459.9

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

424

1.13

0.17

5.0

3.0

u/l

79.9

48.7

1.30

395

(3020564) Creatinine [Moles/volume] in Serum or Plasma

701

1.16

0.14

37.6

15.7

umol/l

84.8

83.2

0.20

701

(3009542) Hematocrit [Volume Fraction] of Blood

592

1.10

0.11

34.7

14.3

36.0

40.8

1.91

382

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.17

0.10

1.4

1.7

—

(3000492) Spirometry study

1.04

0.09

1.0

1.5

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.07

0.07

3.5

2.1

—

(40768797) Stomach Pathology biopsy report

1.14

0.07

1.0

1.1

—

(3015736) pH of Urine

237

1.08

0.06

4.7

3.4

—

(3002385) Erythrocyte distribution width [Ratio]

537

1.01

0.00

37.8

16.3

14.2

13.8

0.93

522

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

705

0.96

0.00

17.8

8.8

u/l

28.8

25.5

0.59

668

(40760892) CBC W Ordered Manual Differential panel - Blood

134

0.96

0.00

6.4

4.2

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

619

1.01

0.00

29.0

12.3

ml/min/173m2

72.2

76.2

0.73

490

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

234

0.98

0.00

4.6

3.5

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

109.7

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.7

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.4

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

0.0

2.2

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

2.0

—

(3000012) Reticulocyte production index

0.00

0.0

2.4

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(4268621)

0.00

0.0

2.0

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.0

1.0

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

3.8

—

(4027681)

0.00

0.0

1.3

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.0

1.4

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.0

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.1

—

258.9

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.2

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.3

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

102.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.4

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

0.0

11.0

—

(4306422)

0.00

0.0

1.3

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.0

1.6

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_LIPORALPHARYNX_EXALLC – Carcinoma in situ of lip, oral cavity and pharynx

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Carcinoma in situ of lip, oral cavity and pharynx

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints