adenoma: The congenital absence of the thyroid gland.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
82 |
4. Check minimum number of eventsNone |
82 |
5. Include endpointsNone |
82 |
6. Filter based on genotype QC (FinnGen only) |
82 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D35
- Name in latin
- Neoplasma benignum corporis pinealis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Pineal gland
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Pineal gland
- Benign neoplasm of other and unspecified endocrine glands
- Benign neoplasm of other and unspecified endocrine glands
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 487 | 326 | 160 |
| Only index persons | 454 | 312 | 142 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 32.24 | 32.69 | 31.22 |
| Only index persons | 31.98 | 31.98 | 31.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 82 | 61 | 21 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 36.89 | 35.46 | 41.04 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 76
- Matched controls
- 757
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D35.4
ICD-10 Finland
Benign neoplasm: Pineal gland
+∞
101.4
73
*
G93.0
ICD-10 Finland
Cerebral cysts
113.6
9.7
10
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.2
8.1
20
36
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
50.4
7.9
9
*
R51.80
ICD-10 Finland
Headache
4.4
7.0
28
88
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_PINEAL and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_PINEAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_PINEAL – Benign neoplasm: Pineal gland
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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