Benign neoplasm of ovary

CD2_BENIGN_OVARY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D27
  • Hospital discharge: ICD-9 220
  • Hospital discharge: ICD-8 220
  • Cause of death: ICD-10 D27
  • Cause of death: ICD-9 220
  • Cause of death: ICD-8 220

2 out of 7 registries used, show all original rules.

7249

4. Check minimum number of events

None

7249

5. Include endpoints

None

7249

6. Filter based on genotype QC (FinnGen only)

7249

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasma benignum ovarii

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 54106 54106 -
Only index persons 48104 48104 -
Unadjusted period prevalence (%)
Whole population 1.55 1.55 -
Only index persons 1.77 1.77 -
Median age at first event (years)
Whole population - 43.07 -
Only index persons - 41.59 -

-FinnGen-

Key figures

All Female Male
Number of individuals 7249 7249 -
Unadjusted period prevalence (%) 2.47 2.47 -
Median age at first event (years) 40.32 40.32 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
6533
Matched controls
65329
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
2200A
ICD-9 Finland
Benign neoplasm of ovary[NEOPLASMA BENIGNUM OVARII]
+∞
323.0
1329
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
3.9
323.0
1597
5056
22099
ICD-8 Finland
Benign neoplasm of ovary, Other and unspecified
+∞
323.0
1694
*
D27.91
ICD-10 Finland
Benign epithelial tumor of the ovary (ovary)
16384.0
323.0
1563
*
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
9.6
323.0
766
895
D27.92
ICD-10 Finland
Benign granulosa cell tumor in ovary (ovary)
1893.0
323.0
378
*
D27.98
ICD-10 Finland
Benign tumor of the ovary (ovary), other specified histology
+∞
323.0
465
*
D27.99
ICD-10 Finland
Benign tumor of the ovary (ovary), unspecified histology
1374.1
323.0
733
6
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
9.3
298.0
655
775
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
7.9
265.9
645
892
22005
ICD-8 Finland
NA
+∞
257.0
245
*
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
10.4
247.3
507
524
D27
ICD-10 Finland
Benign neoplasm of ovary
238.6
202.9
208
9
8204
FHL
Salpingo-oophorectomy
9.6
178.7
381
419
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
10.7
175.1
351
344
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
4.6
170.8
639
1495
LCD00
NOMESCO Finland
Hysterectomy
3.6
156.4
785
2391
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
9.2
127.5
276
310
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
3.1
119.8
743
2622
Q50.10
ICD-10 Finland
A developmental cyst in the ovary
10.7
114.2
227
218
22010
ICD-8 Finland
NA
+∞
107.6
103
*
8202
FHL
Oophorectomy
17.6
101.5
162
94
121
Kela drug reimbursment
Severe hypofunction of sexual glands
4.8
89.1
314
681
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.7
87.1
2393
16291
LAC21
NOMESCO Finland
Laparoscopic destruction of lesion of ovary
9.0
73.2
159
180
22001
ICD-8 Finland
NA
+∞
70.9
68
*
D39.11
ICD-10 Finland
Epithelial tumor of uncertain nature in the ovary
8.4
70.2
159
193
LAE11
NOMESCO Finland
Unilateral laparoscopic oophorectomy
9.8
65.8
136
141
8307
FHL
Hysterectomy and unilateral removal of adhesions
5.5
64.3
199
373
D27.93
ICD-10 Finland
Benign ovarian tumor, sex chord stroma derived
+∞
57.4
55
*
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
2.7
55.5
418
1639
D39.19
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary with unspecified histology
8.5
54.5
122
146
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
4.4
53.6
201
464
22002
ICD-8 Finland
NA
+∞
52.1
50
*
6146A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Pelvic peritoneal adhesions, female
4.4
50.6
191
444
61520
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) follicularis ovarii (retentio)
4.1
49.0
197
487
8472/1-C56.9
ICD-O-3
Mucinous cystic tumor of borderline malignancy of ovary
17.1
48.9
78
46
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
5.4
47.0
146
276
JAL30
NOMESCO Finland
Omentectomy
4.2
46.9
184
445
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
45.4
1504
10358
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
44.8
2340
17879
LAD01
NOMESCO Finland
Laparoscopic partial excision of ovary
11.7
42.3
79
68
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
3.5
42.3
204
591
1413
FHL
Laparoscopy and other therapeutic procedure
2.8
42.2
293
1093
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.4
41.6
4339
37744
21899
ICD-8 Finland
Uterine fibroma
2.2
40.9
465
2243
N80.1
ICD-10 Finland
Endometriosis of ovary
3.0
40.8
242
817
8351
FHL
Removal of pelvic floor brackets
6.1
40.3
112
185
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
3.8
39.8
177
480
N83.5
ICD-10 Finland
Torsion of ovary, ovarian pedicle and fallopian tube
8.2
38.7
88
109
JEA00
NOMESCO Finland
Appendectomy
2.2
38.4
409
1912
LAE10
NOMESCO Finland
Unilateral oophorectomy
8.2
38.4
87
107
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
38.2
2265
17590
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.3
37.6
354
1560
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.8
36.9
714
4202
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
36.0
785
4792
JAH01
NOMESCO Finland
Laparoscopy
2.3
35.3
350
1583
N02BE01
ATC
paracetamol; systemic, rectal
1.5
34.5
5608
52033
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
3.8
34.5
150
399
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.7
32.9
814
5143
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
4.1
32.2
129
320
D39.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Ovary
7.3
32.1
78
108
8308
FHL
Hysterectomy and bilateral adnexal removal
2.8
32.1
211
762
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
30.8
2416
19523
JAL00
NOMESCO Finland
Biopsy of peritoneum
5.8
30.6
88
153
WX402
NOMESCO Finland
General anaesthesia
1.6
29.8
983
6678
8442/1-C56.9
ICD-O-3
Serous borderline tumor, NOS, of ovary
8.1
29.7
67
83
2180A
ICD-9 Finland
Uterine leiomyoma, Submucous leiomyoma of uterus
1.8
28.7
542
3155
D39.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Uterus
5.2
28.7
90
174
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
28.2
1553
11743
D279
ICD-10 Finland
NA
+∞
27.1
26
*
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
2.9
26.3
168
596
B01AB05
ATC
enoxaparin; parenteral
1.4
25.5
1871
14828
N83.1
ICD-10 Finland
Corpus luteum cyst
3.4
24.2
120
358
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
3.6
24.2
112
317
1411
FHL
Laparoscopy and cyst puncture
5.2
23.9
75
146
61510
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Hydrosalpinx
5.1
23.8
75
147
22012
ICD-8 Finland
NA
+∞
22.9
22
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
22.5
1311
9953
B01AB10
ATC
tinzaparin; parenteral
1.7
22.3
438
2577
62530
ICD-8 Finland
Other diseases of uterus, Endometriosis ovarii
2.9
22.1
140
498
N83.0
ICD-10 Finland
Follicular cyst of ovary
2.8
20.9
134
480
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
2.4
20.4
180
772
61521
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) corporis lutei ovarii
3.7
19.8
87
237
Z3231
NOMESCO Finland
Registered nurse
1.3
19.1
1488
11805
6171A
ICD-9 Finland
Endometriosis of ovary
2.6
19.0
139
541
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
2.0
18.8
259
1351
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.6
18.3
445
2783
LAC00
NOMESCO Finland
Excision of ovarian cyst
6.8
17.7
44
65
R2110
NOMESCO Finland
Giving the first information
1.6
17.5
445
2819
LAD00
NOMESCO Finland
Partial excision of ovary
7.6
17.3
40
53
6200A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Follicular cyst of ovary
3.4
16.7
81
241
RD211
NOMESCO Finland
NA
1.9
16.5
254
1379
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
1.7
16.1
346
2095
Q50.11
ICD-10 Finland
Multiple developmental cysts in the ovaries
16.7
16.0
25
15
C56.92
ICD-10 Finland
Malignant ovarian tumor, sex chord stroma derived
8.5
15.9
34
40
22011
ICD-8 Finland
NA
+∞
15.6
15
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
15.6
575
3976
62550
ICD-8 Finland
NA
3.1
15.5
83
266
D39.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Female genital organ, unspecified
4.5
15.5
54
120
62801
ICD-8 Finland
Sterility, female, Sterilitas secundaria
3.1
15.5
84
272
A02BC05
ATC
esomeprazole; systemic
1.2
14.9
2476
21529
8209
FHL
Other measure in this category
7.2
14.7
35
49
61598
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Alii definiti
4.2
14.5
54
129
1410
FHL
Laparoscopy
1.8
14.5
239
1333
N02AX02
ATC
tramadol; systemic, rectal
1.2
14.4
2324
20118
Z2221
NOMESCO Finland
Medical doctor
1.3
14.3
1557
12863
N83.9
ICD-10 Finland
Noninflammatory disorder of ovary, fallopian tube and broad ligament, unspecified
4.1
14.0
54
133
LCB11
NOMESCO Finland
Laparoscopic myomectomy
6.0
14.0
38
64
C56.72
ICD-10 Finland
Mucinous epithelial carcinoma of the ovary
7.0
13.8
33
47
8206
FHL
Removal of the parovarial cyst
8.8
13.4
28
32
8305
FHL
Supravaginal amputation or resection
2.0
13.4
172
875
J01DA01
ATC
[U] cefalexin; systemic
1.2
13.4
3749
34292
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
1.8
13.2
246
1425
J01DB01
ATC
cefalexin; oral
1.2
13.1
4928
46449
S18
ICPC
Laceration/cut
1.2
13.0
2310
20140
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
12.9
1534
12779
UJF32
NOMESCO Finland
Coloscopy
1.3
12.8
1466
12152
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
2.3
12.8
121
543
LAC20
NOMESCO Finland
Destruction of lesion of ovary
8.0
12.8
28
35
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
12.6
1464
12163
22000
ICD-8 Finland
NA
+∞
12.5
12
*
A02BC02
ATC
pantoprazole; systemic
1.2
12.4
3962
36570
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.4
12.3
575
4165
P01AB01
ATC
metronidazole; oral, rectal
1.2
12.2
2524
22317
8203
FHL
Salpingectomy
3.7
12.1
51
138
23599
ICD-8 Finland
Neoplasm of unspecified nature of ovary
6.5
12.0
30
46
6282A
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE PRIM]
4.2
11.9
44
106
JN4BD
NOMESCO Finland
Extensive body CT
1.4
11.4
540
3925
6140A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Acute salpingitis and oophoritis[S-O-ITIS ACUTA]
2.7
11.3
73
268
WX704
NOMESCO Finland
Intubation
1.5
11.3
363
2435
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
11.1
1021
8216
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
2.5
11.1
82
325
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.5
11.0
335
2220
62630
ICD-8 Finland
Disorders of menstruation, Painful
2.5
10.9
81
322
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
10.9
472
3373
N80.0
ICD-10 Finland
Endometriosis of uterus
1.9
10.5
152
815
XLA10
NOMESCO Finland
NA
1.5
10.5
374
2569
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
1.3
10.3
641
4878
N06AA09
ATC
amitriptyline; systemic
1.4
10.2
630
4785
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.5
10.2
383
2663
LAE20
NOMESCO Finland
Bilateral oophorectomy
3.5
10.1
45
128
8341
FHL
Colony removal or incineration
3.4
10.1
47
139
8302
FHL
Tumor removal (e.g., enucleation) or polyp removal
2.9
10.1
60
211
UKC02
NOMESCO Finland
Cystoscopy
1.4
10.1
574
4303
J02AC01
ATC
fluconazole; systemic
1.2
10.0
2821
25512
8620/1-C56.9
ICD-O-3
Adult granulosa cell tumor of testis of ovary
10.0
10.0
19
19
C56.91
ICD-10 Finland
Malignant granulosa cell tumor in ovary
9.1
10.0
20
22
D25.2
ICD-10 Finland
Subserosal leiomyoma of uterus
1.9
10.0
143
764
J01AA02
ATC
doxycycline; systemic
1.2
9.9
4858
46114
62551
ICD-8 Finland
NA
4.2
9.8
36
87
A02BC01
ATC
omeprazole; systemic
1.2
9.8
1548
13250
K59.0
ICD-10 Finland
Constipation
1.5
9.7
282
1848
J01FA06
ATC
roxithromycin; oral
1.2
9.7
2394
21380
K66.0
ICD-10 Finland
Peritoneal adhesions
3.3
9.7
47
144
D39.18
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary with other definite histology
13.4
9.6
16
12
6421
FHL
Appendicectomy
1.6
9.6
276
1807
6201A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Corpus luteum cyst or haematoma
3.0
9.6
53
178
8470/3-C56.9
ICD-O-3
Mucinous cystadenocarcinoma, NOS, of ovary
7.8
9.6
21
27
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
9.6
5547
53441
ZXE00
NOMESCO Finland
One hour or less
1.2
9.3
2180
19355
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
9.3
612
4696
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
9.2
988
8100
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.2
9.1
1583
13658
63151
ICD-8 Finland
Ectopic pregnancy, Tubaria NUD sepsi non indicata
2.5
9.1
67
268
8620/3-C56.9
ICD-O-3
Adult granulosa cell tumor of ovary of ovary
8.3
9.0
19
23
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.6
8.9
223
1412
63110
ICD-8 Finland
Ectopic pregnancy, Tubaria rupta, cum sepsi
4.0
8.9
34
86
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
8.9
741
5880
8306
FHL
Hysterectomy (related to abortion 8516, prolapse correction 8436)
1.5
8.9
263
1736
M01AC06
ATC
meloxicam; systemic, rectal
1.2
8.8
2269
20296
ZXA00
NOMESCO Finland
Right side
1.2
8.7
1528
13192
-60
ICPC
Result test/procedure
1.5
8.7
297
2025
C07AB07
ATC
bisoprolol; oral
1.2
8.6
2507
22633
62620
ICD-8 Finland
Disorders of menstruation, Excessive
1.9
8.6
124
665
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
3.0
8.6
47
158
D01
ICPC
Abdominal pain/cramps general
1.3
8.5
544
4158
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
2.1
8.4
90
431
9080/3-C56.9
ICD-O-3
Teratoma, malignant, NOS, of ovary
90.2
8.4
9
*
62532
ICD-8 Finland
Other diseases of uterus, Endometriosis retro-cervicalis sive retrouterina
1.9
8.4
112
587
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.6
8.3
196
1223
22090
ICD-8 Finland
NA
+∞
8.3
8
*
SPAT1153
SPAT
Removal of sutures
1.2
8.3
1747
15329
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.4
8.3
420
3090
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
8.2
908
7464
D06
ICPC
Abdominal pain localized other
1.4
8.2
431
3190
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
8.2
2259
20287
M79.7
ICD-10 Finland
Fibromyalgia
1.6
8.1
207
1320
LAE21
NOMESCO Finland
Bilateral laparoscopic oophorectomy
3.5
8.1
36
104
JAL31
NOMESCO Finland
Laparoscopic omentectomy
3.4
8.0
36
105
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
2.4
8.0
64
269
WX110
NOMESCO Finland
Local anesthesy
1.2
8.0
3918
36769
M01AE02
ATC
naproxen; oral, rectal
1.2
8.0
3286
30424
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
7.9
2094
18730
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
1.6
7.8
218
1422
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.5
7.8
248
1667
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.2
7.8
874
7198
ZXE20
NOMESCO Finland
More than three and less than five hours
1.3
7.7
636
5037
G03FA01
ATC
norethisterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
0.8
7.6
787
9497
R4110
NOMESCO Finland
Physiotherapy
1.2
7.6
1407
12190
LCD11
NOMESCO Finland
Laparoscopically assisted vaginal hysterectomy
1.9
7.6
107
572
61200
ICD-8 Finland
NA
3.0
7.5
40
133
56899
ICD-8 Finland
Peritoneal adhesions
5.1
7.5
22
43
Q50.1
ICD-10 Finland
Developmental ovarian cyst
10.0
7.5
14
14
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
7.5
2519
22927
LCA06
NOMESCO Finland
Biopsy of endometrium
1.2
7.5
856
7059
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.5
7.4
281
1962
8219
FHL
Other measure in this category
3.5
7.3
32
92
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.4
7.3
312
2225
JAH00
NOMESCO Finland
Laparotomy
1.8
7.3
122
693
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
7.3
1944
17376
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
1.6
7.2
170
1062
N80.9
ICD-10 Finland
Endometriosis, unspecified
2.1
7.2
79
385
D02
ICPC
Abdominal pain epigastric
1.4
7.2
299
2124
LBE00
NOMESCO Finland
Salpingectomy
2.7
7.2
46
170
C56.00
ICD-10 Finland
Malignant tumor of the ovary without histology
2.4
7.1
55
229
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.4
7.1
307
2198
2395A
ICD-9 Finland
Neoplasm of unspecified nature, Other genito-urinary organs
5.6
7.0
19
34
6173A
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS SEROSAE PELVIS]
2.2
7.0
65
294
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
1.6
7.0
155
956
R51.80
ICD-10 Finland
Headache
1.3
7.0
747
6108
N83.8
ICD-10 Finland
Other noninflammatory disorders of ovary, fallopian tube and broad ligament
3.3
7.0
32
96
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.4
7.0
383
2858
L01
ICPC
Neck symptom/complaint
1.2
7.0
755
6183
L17
ICPC
Foot/toe symptom/complaint
1.2
7.0
1390
12112
ZXA05
NOMESCO Finland
Left side
1.2
6.9
1383
12054
LAC10
NOMESCO Finland
Fenestration or marsupialisation of ovarian cyst
13.8
6.9
11
8
R03AC02
ATC
salbutamol; inhalant
1.1
6.8
3044
28214
LCC10
NOMESCO Finland
Supravaginal hysterectomy
2.7
6.8
44
163
C08CA01
ATC
amlodipine; oral
1.2
6.8
1804
16088
LAB11
NOMESCO Finland
Laparoscopic biopsy of ovary
8.2
6.8
14
17
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.6
6.8
152
940
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
2.0
6.8
78
390
Z3226
NOMESCO Finland
Physiotherapist
1.2
6.7
946
7970
SPAT1131
SPAT
Colonoscopy
1.6
6.7
163
1032
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
6.7
701
5723
N95.1
ICD-10 Finland
Menopausal and female climacteric states
1.3
6.7
625
5033
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.3
6.6
656
5319
M79.6
ICD-10 Finland
Pain in limb
1.2
6.6
2050
18499
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
3.1
6.6
33
106
TLE20
NOMESCO Finland
Transvaginal puncture of cul-de-sac
3.1
6.6
33
106
H02AB06
ATC
prednisolone; systemic
1.1
6.6
2594
23816
61593
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Torsio adnexorum
8.7
6.5
13
15
M25.5
ICD-10 Finland
Pain in joint
1.2
6.5
1613
14308
8221
FHL
Sterilization of the laparotomy pathway
1.5
6.5
227
1562
61207
ICD-8 Finland
Acute salpingitis and oophoritis, suspecta
2.0
6.4
71
349
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
3.1
6.4
32
103
5680A
ICD-9 Finland
Other disorders of peritoneum, Peritoneal adhesions
4.7
6.4
20
43
N03AX16
ATC
pregabalin; oral
1.2
6.4
1308
11419
6209X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Unspecified noninflammatory disorder of ovary, Fallopian tube and broad ligament
5.5
6.3
17
31
M03BX02
ATC
tizanidine; oral
1.1
6.3
3643
34301
M54.5
ICD-10 Finland
Low back pain
1.2
6.3
1798
16118
22091
ICD-8 Finland
NA
+∞
6.2
6
*
N81.6
ICD-10 Finland
Rectocele
1.3
6.2
494
3894
JAL20
NOMESCO Finland
Excision or destruction of lesion of peritoneum
2.6
6.2
41
157
JAH96
NOMESCO Finland
Other opening of peritoneal cavity
7.0
6.2
14
20
L02AE01
ATC
buserelin; implant, nasal, parenteral
2.0
6.2
71
353
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
1.6
6.2
159
1020
ZXC40
NOMESCO Finland
Use of ultrasound
2.4
6.2
48
201
Z71.8
ICD-10 Finland
Other specified counselling
1.2
6.2
1201
10430
JAL01
NOMESCO Finland
Laparoscopic biopsy of peritoneum
3.2
6.2
29
90
A01
ICPC
Pain general/multiple sites
1.3
6.1
402
3085
Y4300
ICD-8 Finland
Preventive sterilization, Legal sterilization, medical reasons (illness or physical injury)
1.6
6.1
157
1008
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.2
6.1
1204
10468
8216
FHL
Applicatio ovii
4.2
6.1
21
50
R52.2
ICD-10 Finland
Other chronic pain
1.5
6.1
167
1090
N06AB03
ATC
fluoxetine; oral
1.2
6.0
689
5676
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
4.9
6.0
18
37

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_OVARY and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_OVARY 1.156 [1.06, 1.26] < 0.001
Birth year 0.996 [0.99, 1.0] 0.318

During the follow-up period (1.1.1998 — 31.12.2019), 2472 out of 17767 females with CD2_BENIGN_OVARY died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_OVARY.

N-year risk Females Males
1 0.095% No data
5 0.651% No data
10 1.708% No data
15 3.314% No data
20 5.987% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_OVARY – Benign neoplasm of ovary

GWS hits: 9

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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