Benign neoplasm of eye and adnexa

CD2_BENIGN_EYE

retroperitoneal cancer: An organ system cancer located_in the retroperitoneal space that is manifested in retroperitoneal space in the abdominal cavity behind the peritoneum.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D31
  • Cause of death: ICD-10 D31

2 out of 7 registries used, show all original rules.

3646

4. Check minimum number of events

None

3646

5. Include endpoints

3852

6. Filter based on genotype QC (FinnGen only)

3852

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 25204 14659 10446
Only index persons 23577 13924 9653
Unadjusted period prevalence (%)
Whole population 0.37 0.42 0.29
Only index persons 0.45 0.51 0.37
Median age at first event (years)
Whole population 59.42 59.87 58.81
Only index persons 59.42 59.84 58.81

-FinnGen-

Key figures

All Female Male
Number of individuals 3852 2323 1529
Unadjusted period prevalence (%) 0.75 0.79 0.67
Median age at first event (years) 61.56 59.51 64.68

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3391
Matched controls
33907
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
1784.1
323.0
1831
22
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
2603.4
323.0
908
5
XCK10
NOMESCO Finland
Photography of fundus of eye
6.3
305.4
933
1929
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
8.2
288.0
706
1059
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
148.9
283.8
299
22
XCD10
NOMESCO Finland
Electrophysiological examination of eye
14.8
244.9
426
325
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
48.8
207.1
253
56
D31.2
ICD-10 Finland
Benign neoplasm: Retina
+∞
172.4
164
*
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
+∞
168.1
160
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.6
159.6
629
1613
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.4
159.4
927
3344
D31.9
ICD-10 Finland
Benign neoplasm: Eye, unspecified
+∞
116.3
111
*
CFA20
NOMESCO Finland
Biopsy of conjunctiva
87.3
112.9
126
15
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.3
107.6
626
2181
22400
ICD-8 Finland
Benign neoplasm of eye, Conjunctivae
+∞
96.3
92
*
D31.4
ICD-10 Finland
Benign neoplasm: Ciliary body
+∞
87.9
84
*
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
63.8
69.8
81
13
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
63.8
429
1609
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
63.3
1545
10502
CF2S4
NOMESCO Finland
Photography of conjunctiva
49.3
52.2
63
13
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
64.4
49.3
57
9
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
64.4
49.3
57
9
CBB30
NOMESCO Finland
Excision of lesion of eyelid
4.2
46.7
184
452
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
3.8
42.6
190
521
XCD20
NOMESCO Finland
Photoangiography of eye
5.9
41.8
121
212
2243A
ICD-9 Finland
Benign neoplasm of eye, Conjunctiva
+∞
40.7
39
*
D31.1
ICD-10 Finland
Benign neoplasm: Cornea
+∞
40.7
39
*
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
52.9
39.5
47
9
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
10.8
39.5
77
73
D31.5
ICD-10 Finland
Benign neoplasm: Lacrimal gland and duct
+∞
38.6
37
*
CBA10
NOMESCO Finland
Biopsy of eyelid
9.5
38.4
80
86
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
21.1
37.9
56
27
ZXA00
NOMESCO Finland
Right side
1.7
37.7
956
6289
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.6
32.2
1156
8287
3401
FHL
Removal of local modification or taking a specimen in the operating room
114.5
31.7
34
*
CAA30
NOMESCO Finland
Biopsy of orbit
70.6
30.9
35
5
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
30.2
464
2562
ZXA05
NOMESCO Finland
Left side
1.6
29.4
867
5873
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
28.5
359
1828
ZXA10
NOMESCO Finland
Bilateral
1.7
28.0
642
4039
CH2S4
NOMESCO Finland
Photography of iris
64.5
27.9
32
5
CD2S4
NOMESCO Finland
Photography of eye
10.7
27.5
53
50
WX140
NOMESCO Finland
Parabulbar anesthesy
2.8
27.4
182
669
WX002
NOMESCO Finland
Sedation and analgesia
1.7
26.2
670
4343
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
+∞
26.1
25
*
Z2221
NOMESCO Finland
Medical doctor
1.6
25.4
884
6209
ZXE00
NOMESCO Finland
One hour or less
1.5
24.9
1248
9520
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.0
23.8
315
1634
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
22.6
1218
9377
A98
ICPC
Health maint/preventive medicine
1.9
21.2
3178
30057
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
20.4
1368
10928
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
8.3
20.4
45
55
WX110
NOMESCO Finland
Local anesthesy
1.4
20.3
2105
18199
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
19.8
822
5957
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
19.2
945
7090
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
8.0
18.7
42
53
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
18.0
787
5747
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
18.0
1114
8710
XCK00
NOMESCO Finland
Perimetry
2.0
17.3
238
1252
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
13.3
16.9
29
22
22405
ICD-8 Finland
Benign neoplasm of eye, Orbitae
+∞
16.7
16
*
C69.00
ICD-10 Finland
Malignant tumor of the conjunctiva without histology
170.8
16.5
17
*
S18
ICPC
Laceration/cut
1.4
16.2
1296
10545
ZXD20
NOMESCO Finland
Day surgery
1.6
15.7
396
2530
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
10.1
15.4
30
30
XCH00
NOMESCO Finland
Eye pressure measurement
2.3
15.1
141
629
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
14.9
237
1314
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
14.8
267
1545
C69.3
ICD-10 Finland
Malignant neoplasm: Choroid
31.8
14.8
19
6
H01.0
ICD-10 Finland
Blepharitis
2.1
14.8
172
846
H05.2
ICD-10 Finland
Exophthalmic conditions
9.7
14.7
29
30
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
9.7
14.7
29
30
2241A
ICD-9 Finland
Benign neoplasm of eye, Orbit
+∞
14.6
14
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
5.7
14.5
41
73
H00.1
ICD-10 Finland
Chalazion
2.4
14.1
117
492
H31.9
ICD-10 Finland
Disorder of choroid, unspecified
42.7
14.1
17
*
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
13.9
201
1079
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.6
13.8
353
2260
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.3
13.8
132
596
H40.0
ICD-10 Finland
Glaucoma suspect
1.8
13.6
242
1391
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
13.8
13.2
22
16
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.1
12.7
139
666
8720/3-C69.9
ICD-O-3
Malignant melanoma, NOS, of eye, NOS
32.1
12.6
16
5
C69.02
ICD-10 Finland
Malignant tumor in conjunctival melanoma
+∞
12.5
12
*
CK2J4
NOMESCO Finland
Infrared imaging of ocular fundus
+∞
12.5
12
*
8720/3-C69.3
ICD-O-3
Malignant melanoma, NOS, of choroid
130.5
12.4
13
*
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
2.1
12.2
133
637
D18.0
ICD-10 Finland
Haemangioma, any site
2.8
12.2
76
273
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.5
12.1
92
372
H26.4
ICD-10 Finland
After-cataract
1.7
12.0
283
1770
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
21.3
12.0
17
8
J01DB01
ATC
cefalexin; oral
1.3
11.9
2543
23464
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.9
11.7
168
903
CH3S4
NOMESCO Finland
Photography of iridocorneal angle
+∞
11.5
11
*
F29
ICPC
Eye symptom/complaint other
1.7
11.5
243
1477
C69.39
ICD-10 Finland
Malignant tumor in chorioidea other or unspecified histology
120.4
11.4
12
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.9
11.3
163
877
R01AD09
ATC
mometasone; nasal
1.3
11.2
1270
10716
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.0
11.2
150
786
R42
ICD-10 Finland
Dizziness and giddiness
1.4
11.0
624
4736
Z3231
NOMESCO Finland
Registered nurse
1.3
10.9
799
6321
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.7
10.8
247
1536
SPAT1153
SPAT
Removal of sutures
1.3
10.7
964
7864
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
10.6
716
5590
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
10.4
521
3863
CAB10
NOMESCO Finland
Lateral orbitotomy with excision of lesion
110.3
10.4
11
*
D31
ICD-10 Finland
Benign neoplasm of eye and adnexa
+∞
10.4
10
*
2240A
ICD-9 Finland
Benign neoplasm of eye, Eyeball, except conjunctiva, cornea, retina and choroid
+∞
10.4
10
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
10.4
444
3192
J01FA10
ATC
azithromycin; systemic
1.3
10.3
1673
14725
CKC12
NOMESCO Finland
Photocoagulation of retina
2.0
10.2
129
661
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.2
10.1
96
435
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
10.0
1055
8781
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.1
9.9
109
527
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
16.7
9.9
15
9
A02BC05
ATC
esomeprazole; systemic
1.3
9.8
1182
9999
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.8
1151
9708
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.8
9.7
167
955
R51.80
ICD-10 Finland
Headache
1.5
9.7
383
2715
AA1AD
NOMESCO Finland
CT of head and brain
1.3
9.6
693
5455
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.6
9.6
252
1623
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
3.0
9.5
51
169
H31.8
ICD-10 Finland
Other specified disorders of choroid
+∞
9.4
9
*
E0000UV
ATC
NA
1.3
9.3
1103
9303
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
9.2
605
4692
G04BD12
ATC
mirabegron; oral
1.5
9.1
294
1993
CBB00
NOMESCO Finland
Excision of chalazion
3.1
9.0
48
158
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
9.0
820
6670
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
5.6
9.0
25
45
C69.40
ICD-10 Finland
Malignant tumor of ciliary body without histology
36.8
9.0
11
*
S82
ICPC
Naevus/mole
1.5
9.0
341
2392
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
6.5
8.9
22
34
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
6.1
8.9
23
38
P20
ICPC
Memory disturbance
1.5
8.9
340
2388
CA1ME
NOMESCO Finland
Ultrasound oculometry
4.2
8.9
32
77
J01CA04
ATC
amoxicillin; systemic
1.3
8.8
2442
22702
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
2.9
8.8
51
177
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.1
8.8
94
451
H02.4
ICD-10 Finland
Ptosis of eyelid
2.2
8.6
84
389
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
8.6
1820
16380
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
8.5
983
8238
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
9.0
8.5
17
19
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
8.4
359
2578
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.4
1209
10403
C69.60
ICD-10 Finland
Malignant tumor in orbit without histology
90.3
8.4
9
*
A02BC02
ATC
pantoprazole; systemic
1.2
8.4
1962
17827
2248X
ICD-9 Finland
Benign neoplasm of eye, Other specified parts of eye
+∞
8.3
8
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
5.0
8.3
25
50
N02BE01
ATC
paracetamol; systemic, rectal
1.3
8.2
2710
25605
H25.0
ICD-10 Finland
Senile incipient cataract
1.7
8.2
175
1072
N03AX16
ATC
pregabalin; oral
1.3
8.1
656
5239
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
8.1
924
7728
H52.0
ICD-10 Finland
Hypermetropia
2.8
8.1
49
177
3201
FHL
Removal of a small eyelid tumor in the operating room
22.1
8.0
11
5
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.6
8.0
188
1180
C05AA08
ATC
fluocortolone; rectal, topical
1.4
8.0
384
2822
F38
ICPC
Eye, Other laboratory test NEC
5.3
8.0
23
44
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
7.9
573
4500
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
4.4
7.9
27
62
UJF32
NOMESCO Finland
Coloscopy
1.3
7.9
743
6057
SPAT1262
SPAT
Handing over of treatment supplies
1.3
7.9
508
3919
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
7.9
561
4399
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
7.7
2769
26284
CCA10
NOMESCO Finland
Biopsy of lacrimal gland
45.1
7.7
9
*
H57.1
ICD-10 Finland
Ocular pain
2.0
7.6
90
451
S04
ICPC
Lump/swelling localized
1.5
7.6
246
1670
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
8.0
7.6
16
20
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.5
7.6
33
95
H11.0
ICD-10 Finland
Pterygium
3.7
7.5
31
85
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.5
7.5
264
1827
Z01.2
ICD-10 Finland
Dental examination
1.2
7.5
1106
9514
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
7.5
833
6930
H35.7
ICD-10 Finland
Separation of retinal layers
3.4
7.4
34
102
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
7.4
959
8127
N17
ICPC
Vertigo/dizziness
1.4
7.3
309
2218
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.8
7.2
123
704
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
7.2
858
7196
3402
FHL
Local change removal and plastic (includes pterygium surgery)
20.0
7.1
10
5
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
7.1
247
1703
R03AC02
ATC
salbutamol; inhalant
1.2
7.1
1496
13345
L01
ICPC
Neck symptom/complaint
1.4
7.1
359
2666
F01
ICPC
Eye pain
2.1
7.1
77
374
G44.2
ICD-10 Finland
Tension-type headache
1.4
7.0
346
2557
J01MA02
ATC
ciprofloxacin; systemic
1.2
7.0
1087
9394
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.4
6.9
306
2218
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
6.9
372
2791
SPAT1263
SPAT
Sampling
1.2
6.9
1214
10628
M03BX02
ATC
tizanidine; oral
1.2
6.8
1759
15981
L17
ICPC
Foot/toe symptom/complaint
1.3
6.8
699
5750
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
6.8
1213
10630
C69.42
ICD-10 Finland
Malignant tumor of ciliary melanoma
40.1
6.8
8
*
H05.1
ICD-10 Finland
Chronic inflammatory disorders of orbit
16.7
6.7
10
6
M79.6
ICD-10 Finland
Pain in limb
1.2
6.7
991
8500
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
6.7
1715
15558
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
2.6
6.7
47
184
R44
ICPC
Respiratory, Preventive immunization/medic
2.4
6.7
51
211
H25.8
ICD-10 Finland
Other senile cataract
1.4
6.7
295
2135
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
22.5
6.7
9
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.0
6.7
83
427
R01AD08
ATC
fluticasone; nasal
1.3
6.7
748
6221
H26.2
ICD-10 Finland
Complicated cataract
2.7
6.6
41
152
J02AC01
ATC
fluconazole; systemic
1.2
6.6
1087
9434
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.4
6.6
261
1849
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
6.6
662
5430
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
6.6
292
2117
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.2
6.5
64
299
KH1AD
NOMESCO Finland
CT of urinary organs
1.9
6.5
84
436
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
6.5
1540
13847
H02.8
ICD-10 Finland
Other specified disorders of eyelid
4.8
6.5
20
42
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
3.0
6.5
35
119
VALMI
NOMESCO Finland
NA
1.3
6.5
625
5102
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
6.5
515
4096
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.6
6.4
158
1008
9699/3-C69.6
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of orbit, NOS
70.0
6.4
7
*
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
1.7
6.4
138
849
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.4
1415
12638
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.3
6.4
508
4040
H31.0
ICD-10 Finland
Chorioretinal scars
14.3
6.4
10
7
S01ED51
ATC
timolol, combinations; ophthalmic
1.5
6.4
198
1333
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.6
6.3
167
1088
C69.09
ICD-10 Finland
Malignant tumor in conjunctival other or unspecified histology
+∞
6.2
6
*
9510/3-C69.2
ICD-O-3
Retinoblastoma, NOS, of retina
+∞
6.2
6
*
C69.45
ICD-10 Finland
Melanoma of iris
+∞
6.2
6
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
2.9
6.2
36
126
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
6.2
465
3666
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
6.2
1276
11303
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
2.9
6.2
36
127
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
6.2
742
6211
H33.0
ICD-10 Finland
Retinal detachment with retinal break
1.9
6.2
79
411
A02BC03
ATC
lansoprazole; oral
1.2
6.1
820
6949
-1
NOMESCO Finland
NA
1.2
6.1
867
7395
XCX10
NOMESCO Finland
Other photography of eye
7.7
6.1
13
17
WX402
NOMESCO Finland
General anaesthesia
1.3
6.1
417
3243
WX142
NOMESCO Finland
Sub-tenon anesthesy
4.0
6.1
22
55
H10.4
ICD-10 Finland
Chronic conjunctivitis
3.0
6.1
32
108
KMAK
NOMESCO Finland
NA
1.2
6.1
1402
12554
UKC02
NOMESCO Finland
Cystoscopy
1.3
6.0
422
3293
S01XA18
ATC
ciclosporin; ophthalmic
4.4
6.0
20
46
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
2.8
6.0
35
124
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.0
537
4337

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_EYE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_EYE 0.92 [0.83, 1.02] 0.13
Birth year 0.996 [0.99, 1.0] 0.338

During the follow-up period (1.1.1998 — 31.12.2019), 1518 out of 11421 females with CD2_BENIGN_EYE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_EYE 0.948 [0.84, 1.07] 0.39
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 1366 out of 7991 males with CD2_BENIGN_EYE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_EYE.

N-year risk Females Males
1 0.078% 0.152%
5 0.547% 1.045%
10 1.361% 2.799%
15 2.655% 5.351%
20 4.7% 8.991%

Relationships between endpoints

Index endpoint: CD2_BENIGN_EYE – Benign neoplasm of eye and adnexa

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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