common bile duct neoplasm: Tumor or cancer of the common bile duct including the ampulla of vater and the sphincter of oddi.
Benign neoplasm: Extrahepatic bile ducts
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_EXTRAHEPATIC_BILE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
98 |
4. Check minimum number of eventsNone |
98 |
5. Include endpointsNone |
98 |
6. Filter based on genotype QC (FinnGen only) |
98 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D13
- Name in latin
- Neoplasma benignum ductuum biliarium extrahepaticorum
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Extrahepatic bile ducts
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Extrahepatic bile ducts
- Benign neoplasm: Liver/bile ducts
- Benign neoplasm: Liver/bile ducts
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 741 | 435 | 299 |
| Only index persons | 639 | 388 | 251 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 60.15 | 58.14 | 63.18 |
| Only index persons | 59.14 | 57.39 | 61.84 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 98 | 54 | 44 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 59.65 | 54.98 | 65.39 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 90
- Matched controls
- 899
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.5
ICD-10 Finland
Benign neoplasm: Extrahepatic bile ducts
+∞
116.9
85
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
13.9
22.3
42
53
UJK02
NOMESCO Finland
ERCP
54.6
12.3
14
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
32.7
11.1
14
5
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
49.4
7.9
9
*
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
27.8
7.8
10
*
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
87.0
7.5
8
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
17.6
7.4
11
7
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
5.3
7.1
22
52
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
15.8
6.6
10
7
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
19.7
6.4
9
5
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
31
98
4.16
9.05
2.3
4.7
ug/l
2.8
11.7
1.19
25
78
(3002256) Pathology report gross observation
24
88
3.29
5.43
1.3
1.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
57
375
2.24
3.71
4.0
3.7
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
24
113
2.49
3.35
1.1
1.2
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
54
377
1.96
2.71
10.8
7.0
mmol/l
1.2
1.2
0.28
47
325
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
6
11
5.73
2.58
1.8
1.2
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
8
23
3.69
2.32
1.4
1.2
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
11
43
2.76
2.18
2.5
2.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
43
294
1.82
2.17
2.3
1.9
pmol/l
89.4
96.1
0.44
26
134
(40768804) Tissue Pathology biopsy report
46
323
1.80
2.12
2.7
2.0
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
28
168
1.93
2.11
3.0
1.9
mg/l
3.1
3.2
0.01
23
148
(3013650) Neutrophils [#/volume] in Blood by Automated count
61
472
1.77
1.97
8.6
10.0
e9/l
4.9
4.2
1.25
55
412
(3035350) Ketones [Presence] in Urine by Test strip
51
376
1.74
1.94
5.1
3.9
estimate
0.0
0.0
—
8
71
(3001604) Monocytes [#/volume] in Blood
52
386
1.74
1.93
6.3
5.8
e9/l
0.6
0.6
0.03
44
342
(3017143) Hepatitis C virus Ab [Presence] in Serum
18
95
2.10
1.91
1.6
1.6
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
52
387
1.73
1.91
6.4
5.9
e9/l
0.1
0.0
1.01
45
342
(3037467) Urinalysis macro (dipstick) panel - Urine
66
528
1.77
1.84
5.3
4.2
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
52
392
1.70
1.78
6.3
5.8
e9/l
1.8
1.8
0.12
47
357
(3009261) Glucose [Presence] in Urine by Test strip
51
383
1.69
1.77
5.2
3.8
estimate
0.0
0.0
—
9
68
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
13
63
2.23
1.68
1.1
1.3
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
7
25
2.93
1.68
1.4
1.2
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
27
172
1.79
1.66
2.4
2.2
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
5
14
3.70
1.63
1.8
1.4
mg/l
8.8
13.0
—
5
14
(3049717) Cytology report of Urine Cyto stain
7
26
2.82
1.61
2.0
2.8
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
52
400
1.64
1.59
6.7
6.0
e9/l
0.2
0.2
1.04
47
360
(3015736) pH of Urine
41
298
1.65
1.57
4.8
3.6
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
6
21
2.97
1.53
1.3
1.1
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
21
127
1.83
1.52
1.2
1.3
u/ml
1.1
10.9
1.74
11
50
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
18
104
1.90
1.49
1.7
1.5
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
5
16
3.23
1.45
2.4
2.6
%
237.0
183.0
—
5
16
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
5
16
3.23
1.45
1.0
1.2
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
49
379
1.59
1.42
8.2
5.4
estimate
0.0
0.0
—
9
72
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
9
42
2.26
1.38
1.1
1.8
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
16
92
1.88
1.35
2.4
1.9
ug/g
136.1
157.5
—
10
74
(3021589) Normoblasts [#/volume] in Blood
46
354
1.56
1.35
11.3
9.6
e9/l
0.0
0.0
0.00
35
291
(3000330) Specific gravity of Urine by Test strip
9
43
2.20
1.34
4.2
4.7
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
42
317
1.57
1.33
2.9
2.3
nmol/l
70.7
76.0
0.76
37
275
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
88
795
2.05
1.33
18.5
14.0
mg/l
26.2
23.2
0.29
74
612
(3032080) INR in Blood by Coagulation assay
42
318
1.56
1.31
6.4
7.3
inr
1.1
1.2
—
8
100
(3048929) Epstein Barr virus Ab [Presence] in Serum
5
18
2.87
1.30
1.6
1.3
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
25
168
1.66
1.26
5.6
2.4
e6/l
11.4
5.8
0.38
20
151
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
39
293
1.55
1.25
6.0
3.0
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
19
2.72
1.23
1.6
1.3
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
26
178
1.63
1.22
6.1
5.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
30
213
1.59
1.22
1.5
1.3
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
11
59
1.97
1.12
4.1
3.5
ml/min/173m2
54.4
57.5
—
5
21
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
18
115
1.69
1.09
1.4
1.3
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
32
238
1.51
1.05
3.3
2.3
—
—
—
0
0
(40768793) Breast Pathology biopsy report
5
22
2.34
1.04
1.4
1.2
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
9
48
1.96
1.04
1.6
1.3
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
81
732
1.61
0.98
20.7
14.6
%
38.7
39.9
0.50
57
523
(3007853) Bacteria identified in Skin by Aerobe culture
14
86
1.73
0.97
1.3
1.5
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
20
136
1.59
0.96
1.2
1.3
iu/ml
13.0
37.7
—
5
52
(3030467) Casts [#/volume] in Urine by Automated count
31
233
1.48
0.96
6.7
3.0
e6/l
0.4
0.5
0.10
22
176
(3019550) Sodium [Moles/volume] in Serum or Plasma
88
813
1.81
0.96
22.2
15.9
mmol/l
139.6
139.7
0.16
88
786
(3041096) Erythrocytes [Presence] in Urine by Automated
30
225
1.48
0.94
5.5
3.5
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
12
71
1.79
0.94
2.5
2.4
g/l
0.3
0.2
2.23
12
66
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
6
28
2.22
0.93
1.5
1.6
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
21
146
1.56
0.92
3.2
3.0
ng/l
2894.8
109.8
0.46
16
115
(3020564) Creatinine [Moles/volume] in Serum or Plasma
90
841
1.86
0.92
23.0
16.5
umol/l
81.5
77.2
0.48
90
841
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
29
2.14
0.91
1.3
2.1
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
88
816
1.77
0.90
21.1
15.9
mmol/l
4.0
4.0
0.08
88
788
(36304419) Bacteria [Presence] in Urine
30
228
1.46
0.88
6.7
2.9
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
28
210
1.47
0.87
4.8
4.1
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
24
176
1.48
0.83
1.2
1.2
u/ml
0.4
1.0
—
6
49
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
10
58
1.81
0.83
1.6
1.6
—
—
—
0
0
(3022145) Colonoscopy Study observation
14
91
1.63
0.80
1.6
1.2
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
25
0.00
0.80
0.0
1.5
—
36.2
—
0
25
(3020630) Protein [Mass/volume] in Serum or Plasma
11
67
1.72
0.79
1.4
3.2
g/l
68.4
67.2
0.29
11
61
(3004588) Protein electrophoresis panel - Serum or Plasma
9
53
1.77
0.78
1.1
3.1
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
5
23
2.23
0.77
1.4
1.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
37
299
1.38
0.76
5.3
3.9
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
10
60
1.74
0.75
1.3
2.4
g/l
10.2
10.3
—
10
54
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
22
162
1.46
0.75
2.3
2.8
ug/l
0.6
0.7
0.72
16
108
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
5
26
1.97
0.71
1.0
1.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
5
26
1.97
0.71
1.0
1.3
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
5
26
1.97
0.71
1.0
1.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
32
255
1.38
0.71
6.8
3.0
e6/l
39.0
41.9
0.03
24
198
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
20
146
1.46
0.71
4.3
2.8
e6/l
4.1
1.2
0.39
13
87
(3008898) HLA-B27 [Presence]
5
27
1.90
0.69
1.0
1.1
—
—
—
0
0
(3026782) Osmolality of Urine
21
157
1.43
0.66
4.5
3.0
mosm/kgh2o
594.0
557.6
0.22
14
135
(3018095) Leukocytes [#/volume] in Urine
35
286
1.35
0.66
7.9
3.7
e6/l
63.8
68.8
0.03
25
207
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
33
270
1.34
0.61
4.1
4.8
ug/l
2.1
2.3
0.09
33
236
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
20
0.00
0.61
0.0
1.4
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
0
20
0.00
0.61
0.0
1.8
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
0
20
0.00
0.61
0.0
1.8
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
8
54
1.52
0.59
1.6
1.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
13
91
1.49
0.56
7.2
7.7
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
9
60
1.55
0.56
1.3
1.5
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
6
38
1.62
0.55
1.2
1.2
u/ml
200.1
134.2
—
6
33
(3020682) Albumin/Creatinine [Ratio] in Urine
30
246
1.32
0.55
4.9
3.8
mg/mmol
7.2
9.9
0.20
21
146
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
27
219
1.32
0.53
3.0
4.3
%
22.8
23.2
0.06
14
110
(42870588) Differential panel, method unspecified - Blood
30
248
1.30
0.51
6.9
5.4
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
7
45
1.60
0.50
7.1
6.0
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
20
158
1.33
0.46
1.8
1.8
pmol/l
471.5
475.8
0.02
15
134
(3012516) Albumin [Mass/volume] in Urine
28
235
1.27
0.43
4.0
3.1
mg/l
2560.9
72.7
0.48
18
142
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
(3019225) pH of Specimen
8
61
1.34
0.40
3.0
5.0
—
—
—
0
0
(3000991) Gas panel - Venous blood
9
67
1.38
0.39
15.0
6.7
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
0
19
0.00
0.39
0.0
1.8
—
—
—
0
0
(40758558) Short blood count panel - Blood
24
201
1.26
0.37
5.3
7.8
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
21
173
1.27
0.37
4.3
3.6
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
6
41
1.49
0.37
1.5
1.8
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
6
42
1.46
0.36
2.5
3.9
mmol/l
25.5
24.6
—
6
42
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
6
42
1.46
0.36
1.5
1.3
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
6
44
1.39
0.35
3.3
4.2
%
35.8
48.5
—
6
44
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
46
1.32
0.33
1.0
1.0
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
17
138
1.28
0.33
4.7
2.9
e6/l
0.2
3.0
—
10
80
(1761868) Lipid panel - Serum or Plasma
33
290
1.21
0.33
3.8
3.1
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
7
51
1.40
0.32
33.0
7.4
%
0.7
0.6
—
7
51
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
7
52
1.37
0.32
33.0
7.3
%
1.2
1.7
—
7
52
(3013512) EKG study
26
227
1.20
0.27
4.3
4.0
—
—
—
0
0
(4035726)
10
77
1.33
0.27
1.8
1.2
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
12
96
1.28
0.26
1.5
1.6
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
12
96
1.28
0.26
1.5
1.7
—
—
—
0
0
(3012544) pH of Venous blood
9
76
1.20
0.25
9.3
3.7
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
21
182
1.20
0.24
1.9
1.5
nmol/l
17.3
22.7
1.42
21
149
(40761511) CBC panel - Blood by Automated count
86
835
1.24
0.23
19.2
12.9
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.8
—
13.6
—
0
11
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
10
0.00
0.21
0.0
3.1
—
—
—
0
0
(3003181) Sodium [Moles/volume] in Urine
0
10
0.00
0.21
0.0
1.5
—
60.0
—
0
10
(3051611) Lipemic interference index of Serum or Plasma
0
12
0.00
0.21
0.0
3.1
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
2.5
—
3.4
—
0
13
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
0
14
0.00
0.20
0.0
1.2
—
7.7
—
0
9
(3044889) 12 lead EKG panel
60
572
1.13
0.18
4.4
3.8
—
—
—
0
0
(40761535) Cells panel - Urine sediment
7
62
1.14
0.17
2.0
3.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
67
0.73
0.17
1.2
1.8
—
—
—
0
0
(3000492) Spirometry study
8
71
1.14
0.16
1.4
1.5
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
9
78
1.17
0.16
3.1
3.6
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
29
267
1.12
0.15
3.3
3.6
mmol/l
2.3
2.4
0.32
24
237
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
7
88
0.78
0.15
1.0
1.6
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
34
317
1.11
0.14
3.7
4.0
ng/l
35.9
34.3
0.03
24
221
(3000963) Hemoglobin [Mass/volume] in Blood
90
883
1.24
0.14
30.5
20.7
g/l
132.0
135.7
1.24
90
863
(3035941) MCH [Entitic mass]
90
883
1.24
0.14
30.2
20.4
pg
30.1
30.3
0.59
90
863
(3024731) MCV [Entitic volume]
90
882
1.25
0.14
30.2
20.5
fl
90.4
91.1
0.80
90
862
(3026008) Bacteria identified in Urine by Culture
26
240
1.11
0.13
2.4
3.0
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
47
492
0.91
0.12
2.8
3.0
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
14
124
1.15
0.12
1.4
1.8
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
5
43
1.17
0.10
1.0
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
45
1.12
0.10
1.2
1.6
—
—
—
0
0
(4010399)
6
53
1.14
0.09
1.3
1.4
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
54
1.12
0.09
1.0
1.1
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
6
71
0.84
0.08
1.8
2.0
ug/l
1.6
5.0
—
6
63
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
13
119
1.11
0.06
1.5
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
21
202
1.05
0.02
5.2
3.9
estimate
0.0
0.0
—
9
66
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
76
754
1.04
0.00
19.6
13.5
ml/min/173m2
81.3
81.1
0.02
67
605
(3042936) Bacteria identified in Isolate by Culture
12
118
1.02
0.00
2.8
1.8
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
10
99
1.01
0.00
1.0
1.4
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
13
126
1.04
0.00
1.9
1.8
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
4.0
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.9
—
3.4
—
0
8
(3023511) Choriogonadotropin [Units/volume] in Urine
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
4.0
—
—
—
0
0
(44790047)
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(44790049)
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(44790048)
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(4146454)
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(44806118)
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
(4281824)
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017704) Immunofixation for Urine
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
7
0.00
0.00
0.0
3.9
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
14.6
—
1329.6
—
0
5
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3047189) Immunofixation for 24 hour Urine
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
6
67
0.89
0.00
10.3
3.4
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
1.0
—
0
5
(3016018) Differential panel - Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
11.4
—
0
6
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
68
0.87
0.00
1.3
1.8
—
—
—
0
0
(3000034) Microalbumin [Mass/volume] in Urine
0
6
0.00
0.00
0.0
3.3
—
31.8
—
0
6
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
10.6
—
897.8
—
0
5
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
73.2
—
0
6
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
5
50
1.00
0.00
1.8
1.7
—
—
—
0
0
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3024263) Appearance of Synovial fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
1.8
—
0
5
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
0
5
0.00
0.00
0.0
10.0
—
—
—
0
0
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
37.4
—
0
6
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
5
57
0.87
0.00
1.2
1.8
—
—
—
0
0
(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
2.1
—
19.2
—
0
7
(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
6.6
—
231.2
—
0
5
(4027681)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_EXTRAHEPATIC_BILE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EXTRAHEPATIC_BILE | 1.636 [1.22, 2.19] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.484 |
During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 312 females with CD2_BENIGN_EXTRAHEPATIC_BILE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EXTRAHEPATIC_BILE | 1.638 [1.19, 2.25] | 0.002 |
| Birth year | 0.989 [0.98, 1.0] | 0.018 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 232 males with CD2_BENIGN_EXTRAHEPATIC_BILE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_EXTRAHEPATIC_BILE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.216% | 0.35% |
| 5 | 1.007% | 2.019% |
| 10 | 2.387% | 5.015% |
| 15 | 4.663% | 9.497% |
| 20 | 8.047% | 15.926% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_EXTRAHEPATIC_BILE – Benign neoplasm: Extrahepatic bile ducts
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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