Other benign neoplasms of connective and other soft tissue

CD2_BENIGN_CONNECTIVE_SOFT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D21
  • Cause of death: ICD-10 D21

2 out of 7 registries used, show all original rules.

3180

4. Check minimum number of events

None

3180

5. Include endpoints

4062

6. Filter based on genotype QC (FinnGen only)

4062

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Alia neoplasmata benigna textus connectivi sive alterius textus mollis

Similar endpoints

List of similar endpoints to Other benign neoplasms of connective and other soft tissue based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 30572 17177 13256
Only index persons 27418 15691 11727
Unadjusted period prevalence (%)
Whole population 0.44 0.49 0.37
Only index persons 0.52 0.58 0.45
Median age at first event (years)
Whole population 45.46 46.20 44.41
Only index persons 44.50 45.45 43.23

-FinnGen-

Key figures

All Female Male
Number of individuals 4062 2429 1633
Unadjusted period prevalence (%) 0.78 0.83 0.72
Median age at first event (years) 49.21 47.33 51.99

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3653
Matched controls
36530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
4424.3
323.0
1252
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
56.3
323.0
535
111
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
2290.3
323.0
551
*
D21.0
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of head, face and neck
332.2
323.0
437
15
D21.9
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue, unspecified
473.8
310.4
306
7
21503
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Extremitatis superioris (regione scapulari inclusa)
+∞
183.9
175
*
D21.6
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of trunk, unspecified
+∞
149.0
142
*
D21.3
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of thorax
1292.7
129.0
125
*
21504
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Extremitatis inferioris (regione glutaea inclusa)
+∞
120.5
115
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
10.4
110.5
224
227
21501
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Capitis (facie inclusa) et colli
+∞
109.9
105
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
8.0
108.0
256
340
M67.4
ICD-10 Finland
Ganglion
3.9
83.8
373
1030
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
5.9
80.1
236
423
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
10.8
78.5
155
149
D21.4
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of abdomen
+∞
77.4
74
*
D21.5
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of pelvis
+∞
74.2
71
*
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
7.3
71.8
179
255
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.4
71.7
383
1223
NDR30
NOMESCO Finland
Complete excision of soft tissue tumour of wrist or hand
49.3
67.7
82
17
21509
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Unspecified
+∞
54.3
52
*
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
5.8
53.8
159
285
21502
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Trunci
+∞
50.1
48
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.7
49.9
382
1536
2153C
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Lower limb, including hip[ALARAAJAN BENIGNI PEHMYTKUDOSKASVAIN,HERMOPERÄINEN]
+∞
49.1
47
*
2152A
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,SIDEKUDOSPERÄI]
+∞
45.9
44
*
ZXA00
NOMESCO Finland
Right side
1.8
41.6
971
6233
SPAT1153
SPAT
Removal of sutures
1.7
38.2
1115
7608
S18
ICPC
Laceration/cut
1.6
37.6
1427
10433
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
5.5
37.6
115
216
NHR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of ankle or foot
25.8
36.7
51
20
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
4.9
36.3
123
259
NDM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of wrist or hand
11.0
35.8
69
64
2152X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,TARK MÄÄRITTEL]
+∞
35.5
34
*
N02BE01
ATC
paracetamol; systemic, rectal
1.7
33.9
3009
26798
2153A
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Lower limb, including hip[ALARAAJAN BENIGNI PEHMYTKUDOSKASVAIN,SIDEKUDOSPERÄI]
+∞
33.4
32
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
6.1
33.2
93
157
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
4.5
32.1
116
262
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
12.0
31.1
57
48
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
3.3
30.0
157
490
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
15.7
29.4
48
31
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
28.1
781
5180
ZXA05
NOMESCO Finland
Left side
1.6
27.2
853
5836
2153X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Lower limb, including hip[ALARAAJAN BENIGNI PEHMYTKUDOSKASVAIN,TARK MÄÄRITTEL]
+∞
27.1
26
*
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
15.0
26.0
43
29
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
25.9
1527
12019
J01DB01
ATC
cefalexin; oral
1.5
25.5
2828
25264
N03AX16
ATC
pregabalin; oral
1.6
24.8
769
5226
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
20.8
23.8
35
17
9474
FHL
Soft tissue tumor removal (subcutaneous tumor 9736 skin tumor 9733)
18.2
23.5
36
20
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
21.4
23.4
34
16
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
17.3
23.1
36
21
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.0
23.0
331
1768
ZXE00
NOMESCO Finland
One hour or less
1.5
23.0
1295
10025
2150A
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Head, face and neck[NEOPL BENIG CAPITIS, FACIEI ET COLLI,SIDEKUDOSPER]
+∞
22.9
22
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.2
22.9
247
1173
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.3
22.0
214
969
2152D
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,MUU]
+∞
21.9
21
*
M01AH05
ATC
etoricoxib; oral
1.4
21.8
1942
16329
N02AX02
ATC
tramadol; systemic, rectal
1.4
21.7
1354
10656
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
3.5
21.7
103
300
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
21.3
865
6230
ZXD20
NOMESCO Finland
Day surgery
1.7
20.9
446
2719
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
6.3
20.6
55
89
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
2.9
19.8
122
430
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
19.6
3105
28745
WX204
NOMESCO Finland
Axillary plexus blockaced
2.8
19.0
125
458
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
18.6
294
1627
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
18.5
899
6694
M79.6
ICD-10 Finland
Pain in limb
1.4
18.4
1134
8834
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
18.4
1177
9234
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
5.9
18.2
51
88
S04
ICPC
Lump/swelling localized
1.8
17.8
304
1723
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
17.5
1149
9034
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
11.5
17.5
32
28
9491
FHL
Local soft tissue exploration, drainage, or removal
7.1
17.0
41
58
NHM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of ankle or foot
6.8
16.9
42
62
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
16.8
308
1789
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.8
16.4
69
183
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
16.4
431
2779
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
16.4
443
2880
A02BC05
ATC
esomeprazole; systemic
1.4
16.2
1272
10277
D21
ICD-10 Finland
Other benign neoplasms of connective and other soft tissue
30.2
16.1
21
7
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.0
16.1
215
1119
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
16.0
1118
8854
ND2CG
NOMESCO Finland
Extensive MRI of hand
11.7
16.0
29
25
D17.0
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
3.3
16.0
79
240
D18.0
ICD-10 Finland
Haemangioma, any site
3.0
15.7
91
308
WX110
NOMESCO Finland
Local anesthesy
1.3
15.7
2258
19996
NDR99
NOMESCO Finland
Other operation for tumour of wrist or hand
26.4
15.6
21
8
NCR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of elbow or forearm
22.1
15.5
22
10
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
11.3
15.2
28
25
A02BC01
ATC
omeprazole; systemic
1.4
15.2
848
6448
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
15.1
639
4600
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
6.9
15.1
37
54
J01DA01
ATC
[U] cefalexin; systemic
1.3
15.1
2069
18134
M01AB05
ATC
diclofenac; systemic, rectal
1.3
15.1
2183
19289
A02BC03
ATC
lansoprazole; oral
1.4
14.6
912
7066
UJF32
NOMESCO Finland
Coloscopy
1.4
14.4
781
5897
N03AX12
ATC
gabapentin; oral
1.5
14.3
461
3127
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.9
14.1
219
1200
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
14.0
612
4431
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
4.2
14.0
53
129
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
4.6
14.0
48
106
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.6
13.9
103
408
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.6
13.9
379
2466
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
6.1
13.9
37
61
M25.5
ICD-10 Finland
Pain in joint
1.4
13.8
856
6609
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
13.8
328
2058
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
13.8
1195
9745
2159X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Site unspecified
+∞
13.5
13
*
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
2.6
13.4
99
390
A02BC02
ATC
pantoprazole; systemic
1.3
13.4
2080
18401
M03BX02
ATC
tizanidine; oral
1.3
13.3
2017
17779
P01AB01
ATC
metronidazole; oral, rectal
1.3
13.1
1243
10258
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
13.0
12.9
22
17
2150X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Head, face and neck[NEOPL BENIG CAPITIS, FACIEI ET COLLI,TARK MÄÄRITT]
+∞
12.5
12
*
L08
ICPC
Shoulder symptom/complaint
1.4
12.2
553
4021
WX002
NOMESCO Finland
Sedation and analgesia
1.4
12.2
590
4348
L12
ICPC
Hand/finger symptom/complaint
1.5
11.9
410
2817
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
11.8
481
3421
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
11.8
1291
10818
H02AB06
ATC
prednisolone; systemic
1.3
11.7
1441
12270
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
11.7
139
693
WX320
NOMESCO Finland
Spinalanesthesy
1.4
11.4
654
4965
R51.80
ICD-10 Finland
Headache
1.5
11.4
423
2952
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
2.7
11.4
79
302
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
11.3
450
3186
D48.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Peripheral nerves and autonomic nervous system
17.1
11.2
17
10
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.4
10.9
93
397
K02.1
ICD-10 Finland
Caries of dentine
1.3
10.7
1766
15541
J01AA02
ATC
doxycycline; systemic
1.3
10.6
2571
23713
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
2.1
10.5
119
582
J01FF01
ATC
clindamycin; systemic
1.3
10.4
804
6390
ACB19
NOMESCO Finland
Excision of lesion of peripheral nerve other or unspecified
8.2
10.3
22
27
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
1.9
10.3
145
773
J01FA10
ATC
azithromycin; systemic
1.3
10.3
1848
16398
M01AC06
ATC
meloxicam; systemic, rectal
1.3
10.2
1099
9154
XA402
NOMESCO Finland
ENMG
2.4
10.2
85
360
NB1DG
NOMESCO Finland
Shoulder and humerus very extensive MRI examination with high intensity magnet
4.3
10.2
36
84
WX402
NOMESCO Finland
General anaesthesia
1.4
10.1
481
3528
J01FA06
ATC
roxithromycin; oral
1.3
10.0
1235
10455
J01CA04
ATC
amoxicillin; systemic
1.3
9.9
2676
24881
B01AB05
ATC
enoxaparin; parenteral
1.3
9.9
882
7154
KMAK
NOMESCO Finland
NA
1.3
9.9
1608
14078
SPAT1301
SPAT
No procedures
1.3
9.9
950
7783
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
2.5
9.9
74
298
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
9.9
622
4786
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
9.8
224
1390
L72.1
ICD-10 Finland
Trichilemmal cyst
1.7
9.8
185
1086
WX120
NOMESCO Finland
Intravenous local anesthesy of arm
2.9
9.7
56
192
M54.5
ICD-10 Finland
Low back pain
1.3
9.7
962
7910
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
3.8
9.7
39
103
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
9.6
2245
20459
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
9.5
943
7754
SPAT1263
SPAT
Sampling
1.3
9.5
1306
11193
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.5
9.4
276
1830
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
9.4
1773
15754
C49.19
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder other or unspecified tumor
21.7
9.3
13
6
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
9.3
1465
12742
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.3
1229
10475
JAA10
NOMESCO Finland
Excision of lesion of abdominal wall
10.7
9.3
17
16
J01MA02
ATC
ciprofloxacin; systemic
1.3
9.2
1132
9556
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.2
491
3673
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
9.2
1130
9545
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
13.7
9.2
15
11
4704
FHL
Neck tumor removal
13.7
9.2
15
11
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.3
9.1
84
375
NHM10
NOMESCO Finland
Fasciotomy of ankle or foot
4.8
9.1
29
61
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
9.1
965
7996
WX702
NOMESCO Finland
Supraglottic ventilation device
1.8
9.1
159
914
M19.8
ICD-10 Finland
Other specified arthrosis
2.1
9.0
99
480
ACC51
NOMESCO Finland
Release of median nerve
1.6
9.0
219
1386
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
12.5
8.9
15
12
M02AA07
ATC
piroxicam; topical
1.3
8.8
1071
9020
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
8.8
813
6616
P01BA02
ATC
hydroxychloroquine; oral
1.6
8.7
237
1541
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
8.7
330
2314
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
8.7
1191
10171
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
8.6
237
1545
M48.0
ICD-10 Finland
Spinal stenosis
1.5
8.6
320
2237
J02AC01
ATC
fluconazole; systemic
1.2
8.6
1220
10466
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.6
1131
9615
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
2.2
8.5
86
404
ND3CG
NOMESCO Finland
Extensive MRI of fingers
20.1
8.5
12
6
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
3.3
8.4
40
122
H04.10
ICD-10 Finland
Dry eye syndrome
1.5
8.4
263
1768
2153B
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Lower limb, including hip[ALARAAJAN BENIGNI PEHMYTKUDOSKASVAIN,LIHASKUDOSPERÄ]
+∞
8.3
8
*
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.8
8.3
142
813
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.5
8.3
316
2220
M01AX17
ATC
nimesulide; oral
1.3
8.2
700
5623
D17.9
ICD-10 Finland
Benign lipomatous neoplasm, unspecified
2.8
8.2
52
190
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.6
8.1
201
1277
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
2.5
8.1
58
230
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
8.1
607
4784
M01AH02
ATC
rofecoxib; oral
1.4
8.1
361
2612
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.4
8.1
67
287
TQW99
NOMESCO Finland
Other minor procedure on skin
1.8
8.1
140
805
GAE06
NOMESCO Finland
Excision of lesion of chest wall
11.7
8.1
14
12
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
8.0
1190
10240
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
7.8
338
2430
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
4.7
7.8
25
54
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.6
7.8
205
1324
WZC30
NOMESCO Finland
Teaching
1.4
7.8
367
2685
ND2DG
NOMESCO Finland
Very extensive MRI of hand
45.1
7.7
9
*
9472
FHL
Soft tissue biopsy (muscle, tumor) under general anesthesia or operating room
15.0
7.7
12
8
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
7.7
777
6379
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
7.7
193
1235
S80.0
ICD-10 Finland
Contusion of knee
1.6
7.7
180
1131
M65.3
ICD-10 Finland
Trigger finger
1.8
7.6
119
660
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
7.6
1538
13649
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
2.2
7.6
71
320
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
7.6
586
4636
UDC00
NOMESCO Finland
Ear microscopy
1.6
7.6
192
1226
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
2.1
7.5
83
404
SPAT1312
SPAT
General health counselling
1.3
7.5
932
7840
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.7
7.5
157
958
AA1AD
NOMESCO Finland
CT of head and brain
1.3
7.5
634
5086
N02AA05
ATC
oxycodone; systemic
1.4
7.5
361
2651
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
7.4
279
1954
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.5
7.4
217
1439
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
3.5
7.4
32
92
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
1.9
7.3
101
538
SPAT1260
SPAT
Consultation of another employee
1.3
7.3
494
3834
L17
ICPC
Foot/toe symptom/complaint
1.3
7.3
707
5770
R06AE07
ATC
cetirizine; oral
1.2
7.3
1301
11383
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.6
7.3
165
1027
2153D
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Lower limb, including hip[ALARAAJAN BENIGNI PEHMYTKUDOSKASVAIN,MUU]
+∞
7.3
7
*
2155X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Abdomen[ABDOMENIN BENIGNI PEHMYTKUDOSKASVAIN,TARK MÄÄRITTEL]
+∞
7.3
7
*
2152C
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,HERMOPERÄINEN]
+∞
7.3
7
*
C49.20
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the lower extremity including the hip without histology
10.9
7.3
13
12
ND1DG
NOMESCO Finland
Wrist and hand very extensive MRI examination with high intensity magnet
6.8
7.3
17
25
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
7.2
1991
18192
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.5
7.2
54
221
A02BA02
ATC
ranitidine; systemic
1.3
7.1
550
4351
WX290
NOMESCO Finland
Other blockade of nerve
1.2
7.1
1305
11444
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
7.1
1682
15130
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
7.1
441
3379
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
3.0
7.1
38
128
M01AX05
ATC
glucosamine; oral
1.3
7.1
539
4255
9519
FHL
Other measure in this category
12.0
7.1
12
10
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
1.7
7.1
134
793
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
7.1
605
4855
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
1.7
7.0
134
797
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
3.4
7.0
32
96
J35.0
ICD-10 Finland
Chronic tonsillitis
1.7
7.0
126
733
UKC02
NOMESCO Finland
Cystoscopy
1.4
6.9
407
3089
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.5
6.9
263
1847
WX725
NOMESCO Finland
Noninvasive ventilation
1.7
6.9
126
738
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.6
6.9
166
1051
L82
ICD-10 Finland
Seborrhoeic keratosis
1.4
6.9
406
3084
Z00.0
ICD-10 Finland
General medical examination
1.3
6.9
505
3966
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.4
6.9
317
2311
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
2.1
6.8
76
374
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.6
6.8
184
1198
M01AE02
ATC
naproxen; oral, rectal
1.2
6.8
1735
15687
R05FB02
ATC
cough suppressants and expectorants
1.2
6.8
1103
9537
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
6.8
1600
14365
GA1CG
NOMESCO Finland
Extensive MRI of chest
9.3
6.8
13
14
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
3.0
6.8
36
121
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.7
808
6761
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
1.8
6.7
115
659
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
16.7
6.7
10
6
NC1DG
NOMESCO Finland
Elbow and forearm very extensive MRI examination with high intensity magnet
16.7
6.7
10
6
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
6.7
1211
10586
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
6.7
297
2149
D17
ICD-10 Finland
Benign lipomatous neoplasm
2.6
6.7
44
168
H02.3
ICD-10 Finland
Blepharochalasis
1.6
6.6
147
912
SPAT1202
SPAT
Intra-articular injection
1.9
6.6
91
484
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
6.6
35
118
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
6.6
360
2705
R01AD08
ATC
fluticasone; nasal
1.2
6.5
816
6857
X58
ICD-10 Finland
Exposure to other specified factors
1.4
6.5
372
2814
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
6.5
450
3508
B07.9
ICD-10 Finland
Verruca simplex
1.9
6.5
90
483
ND2CM
NOMESCO Finland
Extensive MRI of hand (more than 1.5 T)
70.0
6.4
7
*
G56.2
ICD-10 Finland
Lesion of ulnar nerve
1.9
6.4
90
486
UJH02
NOMESCO Finland
Anoscopy
1.7
6.4
116
681
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
2.0
6.4
72
356
R13
ICD-10 Finland
Dysphagia
1.6
6.3
160
1028
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.6
6.3
150
946
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.4
6.3
260
1855
L16
ICPC
Ankle symptom/complaint
1.4
6.3
261
1865
1220
FHL
Arthroscopy
1.8
6.3
109
630
ACB99
NOMESCO Finland
Other operation for lesion of peripheral nerve: other or unspecified
18.0
6.3
9
5
R06.5
ICD-10 Finland
Mouth breathing
1.5
6.2
226
1574
2155A
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Abdomen[ABDOMENIN BENIGNI PEHMYTKUDOSKASVAIN,SIDEKUDOSPERÄI]
+∞
6.2
6
*
21505
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Loco multiplici
+∞
6.2
6
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
6.2
240
1691
R06.0
ICD-10 Finland
Dyspnoea
1.3
6.2
677
5596
2377A
ICD-9 Finland
Neoplasm of uncertain behaviour of endocrine glands and nervous system, Neurofibromatosis
26.7
6.2
8
*
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.7
6.2
123
741
B01AB04
ATC
dalteparin; parenteral
1.7
6.2
128
780
R06AX27
ATC
desloratadine; oral
1.2
6.2
758
6349
M01AH01
ATC
celecoxib; oral (coxibs)
1.3
6.2
493
3914
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.7
6.2
107
620
SPAT1310
SPAT
Counselling related to known health issue
1.2
6.2
913
7809
Z01.2
ICD-10 Finland
Dental examination
1.2
6.2
1194
10492
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
6.2
299
2199
R01AD09
ATC
mometasone; nasal
1.2
6.2
1324
11749
E0000UV
ATC
NA
1.2
6.2
1142
9993
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
5.3
6.1
17
32
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
6.1
1283
11355
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.5
6.1
176
1164
QBJ30
NOMESCO Finland
Correction of abdominal apron
3.4
6.1
27
80
Z54.0
ICD-10 Finland
Convalescence following surgery
2.4
6.0
48
205
9271
FHL
Hallux surgery
2.1
6.0
65
316
C05AA08
ATC
fluocortolone; rectal, topical
1.3
6.0
394
3044
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
1.5
6.0
200
1365
R03AC02
ATC
salbutamol; inhalant
1.2
6.0
1581
14278
-1
NOMESCO Finland
NA
1.2
6.0
956
8234

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CONNECTIVE_SOFT and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CONNECTIVE_SOFT 1.099 [0.98, 1.23] 0.096
Birth year 0.993 [0.99, 1.0] 0.118

During the follow-up period (1.1.1998 — 31.12.2019), 1098 out of 10832 females with CD2_BENIGN_CONNECTIVE_SOFT died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_CONNECTIVE_SOFT 1.071 [0.96, 1.19] 0.218
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 1178 out of 8587 males with CD2_BENIGN_CONNECTIVE_SOFT died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CONNECTIVE_SOFT.

N-year risk Females Males
1 0.109% 0.216%
5 0.602% 1.208%
10 1.6% 3.055%
15 3.085% 6.047%
20 5.221% 10.154%

Relationships between endpoints

Index endpoint: CD2_BENIGN_CONNECTIVE_SOFT – Other benign neoplasms of connective and other soft tissue

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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