chondrosarcoma: A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.
Benign neoplasm of bone and articular cartilage
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_BONE_CARTILAGE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2424 |
4. Check minimum number of eventsNone |
2424 |
5. Include endpoints |
3415 |
6. Filter based on genotype QC (FinnGen only) |
3415 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10-D36
- Name in latin
- Neoplasma benignum ossis sive cartilaginis articularis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm of bone and articular cartilage
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of bone and articular cartilage
- Benign neoplasms
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 27315 | 13494 | 13693 |
| Only index persons | 25120 | 12600 | 12520 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.38 | 0.39 | 0.38 |
| Only index persons | 0.47 | 0.46 | 0.48 |
| Median age at first event (years) | |||
| Whole population | 31.98 | 37.34 | 26.57 |
| Only index persons | 30.96 | 36.54 | 25.35 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3415 | 2042 | 1373 |
| Unadjusted period prevalence (%) | 0.66 | 0.70 | 0.61 |
| Median age at first event (years) | 40.09 | 40.27 | 39.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3060
- Matched controls
- 30599
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
10431.2
323.0
792
*
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
+∞
323.0
377
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
59.4
323.0
390
75
D16.49
ICD-10 Finland
Bones of skull and face
+∞
245.1
232
*
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
+∞
237.6
225
*
9102
FHL
Trepanation or removal of the local bone process
64.5
233.0
271
46
D16.3
ICD-10 Finland
Benign neoplasm: Short bones of lower limb
+∞
200.2
190
*
21306
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium longorum extremitatis inferioris
+∞
198.1
188
*
2137A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Long bones of lower limb
+∞
165.1
157
*
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
1548.6
150.2
145
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
16.2
119.5
198
130
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
297.6
112.8
114
*
21307
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis inferioris
+∞
93.2
89
*
D16.8
ICD-10 Finland
Benign neoplasm: Pelvic bones, sacrum and coccyx
+∞
89.0
85
*
2135A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of upper limb
+∞
86.9
83
*
21303
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium longorum extremitatis superioris et scapulae
+∞
83.7
80
*
NHR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of ankle or foot
60.1
70.0
82
14
AAP10
NOMESCO Finland
Extirpation of a skull lesion
349.9
68.8
69
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
52.6
64.3
77
15
2138A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of lower limb
+∞
61.7
59
*
D16.6
ICD-10 Finland
Benign neoplasm: Vertebral column
+∞
59.6
57
*
21304
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis superioris
+∞
58.5
56
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
34.0
55.9
73
22
D16.50
ICD-10 Finland
Benign tumor of the mandibular bone or cartilage
+∞
54.3
52
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
6.2
52.4
146
244
D16.51
ICD-10 Finland
Benign tumor of the mandibular bone with urpsrung in teeth
506.1
50.6
50
*
D16.7
ICD-10 Finland
Benign neoplasm: Ribs, sternum and clavicle
+∞
45.9
44
*
21309
ICD-8 Finland
Benign neoplasm of bone and cartilage, Unspecified
+∞
43.8
42
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
24.4
42.4
60
25
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
38.5
41.9
53
14
2130A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Bones of skull and face
+∞
37.6
36
*
D16.40
ICD-10 Finland
Orbital bone
+∞
36.5
35
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.1
35.1
114
230
21308
ICD-8 Finland
Benign neoplasm of bone and cartilage, Loco alio sive multiplici
+∞
33.4
32
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
4.9
32.5
109
228
2134A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Scapula and long bones of upper limb
+∞
32.3
31
*
9101
FHL
Bone biopsy
26.2
31.9
44
17
N02AX02
ATC
tramadol; systemic, rectal
1.6
31.7
1170
8503
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.2
31.4
351
1709
NF3AA
NOMESCO Finland
Femur X-ray examination
5.7
30.5
90
163
D16
ICD-10 Finland
Benign neoplasm of bone and articular cartilage
+∞
27.1
26
*
9104
FHL
Autogenous bone graft
38.2
27.1
34
9
M79.6
ICD-10 Finland
Pain in limb
1.6
26.1
974
7011
N03AX16
ATC
pregabalin; oral
1.7
26.0
646
4172
NDK10
NOMESCO Finland
Incision or excision of a bone of hand
22.0
25.6
37
17
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
25.4
1309
10134
N02BE01
ATC
paracetamol; systemic, rectal
1.6
25.4
2460
21942
M25.5
ICD-10 Finland
Pain in joint
1.6
25.3
829
5764
21302
ICD-8 Finland
Benign neoplasm of bone and cartilage, Costae, sterni, claviculae
+∞
25.0
24
*
M01AH05
ATC
etoricoxib; oral
1.5
24.4
1675
13745
NGK05
NOMESCO Finland
Partial or total excision of bone of lower leg
34.8
24.3
31
9
21300
ICD-8 Finland
Benign neoplasm of bone and cartilage, Mandibulae (detibus inclusis)
+∞
24.0
23
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.1
23.6
278
1378
9103
FHL
Partial or complete bone removal
17.2
21.8
34
20
NFK10
NOMESCO Finland
Fenestration or partial or total excision of bone of femur
50.4
21.1
25
5
M85.4
ICD-10 Finland
Solitary bone cyst
34.0
21.1
27
8
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.7
20.3
89
244
ZXA05
NOMESCO Finland
Left side
1.6
20.1
639
4369
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.7
20.1
490
3124
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
6.2
20.0
54
89
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
11.3
19.9
37
33
2139X
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Bone and articular cartilage, site unspecified
+∞
19.8
19
*
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
4.6
19.3
68
152
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
19.1
2671
24727
EFA10
NOMESCO Finland
Excision of lesion of jaws
34.5
18.9
24
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
18.7
1058
8191
ZZH40
NOMESCO Finland
Substitute of bone
5.7
18.6
53
94
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
18.5
1026
7911
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
17.9
718
5170
AA1AD
NOMESCO Finland
CT of head and brain
1.6
17.4
571
3923
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.1
17.3
99
331
ZXA00
NOMESCO Finland
Right side
1.5
17.3
668
4758
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
12.0
17.3
31
26
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
17.3
227
1175
21305
ICD-8 Finland
Benign neoplasm of bone and cartilage, Pelvis, sacri, coccygis
+∞
16.7
16
*
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
170.9
16.5
17
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
16.5
964
7467
N06AX21
ATC
duloxetine; oral
1.8
16.4
303
1769
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
16.4
1004
7840
S18
ICPC
Laceration/cut
1.4
16.1
1048
8269
Q78.6
ICD-10 Finland
Multiple congenital exostoses
47.7
16.0
19
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
15.9
582
4092
J01DB01
ATC
cefalexin; oral
1.4
15.8
2353
21387
M54.5
ICD-10 Finland
Low back pain
1.4
15.8
879
6738
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
2.4
15.7
134
572
WX320
NOMESCO Finland
Spinalanesthesy
1.5
15.7
565
3952
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
4.9
15.7
51
106
Q78.48
ICD-10 Finland
Enchondromatosis
+∞
15.6
15
*
2131A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Lower jaw bone
+∞
15.6
15
*
R01AD09
ATC
mometasone; nasal
1.4
15.5
1233
10060
NF1AA
NOMESCO Finland
Hip X-ray examination
2.0
15.5
203
1050
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.9
15.4
241
1332
J01DA01
ATC
[U] cefalexin; systemic
1.4
15.4
1728
14916
EDA10
NOMESCO Finland
Biopsy of mandible
13.1
15.2
26
20
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
15.1
926
7212
M03BX02
ATC
tizanidine; oral
1.4
15.0
1740
15071
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
10.9
15.0
28
26
SPAT1153
SPAT
Removal of sutures
1.4
14.9
787
5959
N03AX12
ATC
gabapentin; oral
1.6
14.9
393
2548
M01AE02
ATC
naproxen; oral, rectal
1.4
14.9
1568
13364
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.8
14.8
62
165
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
31.8
14.8
19
6
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
5.4
14.6
43
80
2136A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Pelvic bones, sacrum and coccyx
+∞
14.6
14
*
D16.41
ICD-10 Finland
Benign tumor of the maxillary bone originating in teeth
+∞
14.6
14
*
D16.5
ICD-10 Finland
Benign neoplasm: Lower jaw bone
+∞
14.6
14
*
A02BC02
ATC
pantoprazole; systemic
1.4
14.5
1703
14738
J01AA02
ATC
doxycycline; systemic
1.4
14.4
2140
19226
NG4AA
NOMESCO Finland
Lower leg X-ray examination
2.8
13.9
91
335
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
13.9
332
2092
X58
ICD-10 Finland
Exposure to other specified factors
1.6
13.9
381
2495
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.7
13.8
59
160
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
13.7
697
5224
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
13.7
1399
11809
21301
ICD-8 Finland
Benign neoplasm of bone and cartilage, Columnae vertebralis (sacro et coccyge exclusis)
+∞
13.5
13
*
R51.80
ICD-10 Finland
Headache
1.6
13.5
398
2647
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.7
13.4
296
1825
NG1AD
NOMESCO Finland
Knee CT examination
4.3
13.4
49
116
NDR30
NOMESCO Finland
Complete excision of soft tissue tumour of wrist or hand
10.5
12.7
24
23
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
70.1
12.6
14
*
J01FF01
ATC
clindamycin; systemic
1.4
12.5
687
5210
NK6DT
NOMESCO Finland
Bone biopsy with MRI guidance
+∞
12.5
12
*
M67.4
ICD-10 Finland
Ganglion
1.9
12.4
175
931
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
12.4
852
6722
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
12.4
946
7595
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
12.3
360
2393
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.7
12.2
290
1824
P01AB01
ATC
metronidazole; oral, rectal
1.3
12.2
1034
8433
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
12.1
163
853
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
2.8
12.0
77
282
M01AB05
ATC
diclofenac; systemic, rectal
1.3
12.0
1810
16036
NFK99
NOMESCO Finland
Other operation on bone of femur
21.4
12.0
17
8
UKC02
NOMESCO Finland
Cystoscopy
1.6
11.8
331
2173
WX204
NOMESCO Finland
Axillary plexus blockaced
2.5
11.8
93
383
J01FA09
ATC
clarithromycin; systemic
1.4
11.8
835
6609
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
11.8
215
1250
ZXE00
NOMESCO Finland
One hour or less
1.3
11.8
1028
8406
A02BC05
ATC
esomeprazole; systemic
1.3
11.8
1029
8418
R01AD12
ATC
fluticasone furoate; nasal
1.4
11.8
800
6290
R52.9
ICD-10 Finland
Pain, unspecified
1.8
11.6
203
1165
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
11.5
204
1177
2133A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Ribs, sternum and clavicle
+∞
11.5
11
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
11.5
11
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
11.4
249
1531
9109
FHL
Other measure in this category
15.1
11.3
18
12
SPAT1263
SPAT
Sampling
1.3
11.3
1095
9082
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
11.3
685
5278
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
11.0
616
4677
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.5
11.0
87
359
L03
ICPC
Low back symptom/complaint
1.4
10.9
595
4501
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
10.8
1313
11222
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
8.9
10.7
22
25
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.6
10.6
251
1577
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
10.6
1450
12574
L08
ICPC
Shoulder symptom/complaint
1.5
10.6
437
3127
WX110
NOMESCO Finland
Local anesthesy
1.3
10.5
1922
17313
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
10.5
578
4368
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
10.5
248
1556
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
10.5
477
3482
J01FA10
ATC
azithromycin; systemic
1.3
10.5
1623
14300
75665
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Exostosis cartilaginea multiplex
110.4
10.4
11
*
R01AD08
ATC
fluticasone; nasal
1.4
10.3
740
5845
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
10.3
1498
13080
SPAT1229
SPAT
Assessment of need for aid
1.8
10.3
164
917
M01AH01
ATC
celecoxib; oral (coxibs)
1.5
10.2
423
3028
M85.6
ICD-10 Finland
Other cyst of bone
23.4
10.2
14
6
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
10.2
219
1342
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
10.2
522
3899
M01AX17
ATC
nimesulide; oral
1.4
10.2
560
4236
R03AC02
ATC
salbutamol; inhalant
1.3
10.1
1380
11943
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.0
1975
17915
ZZH20
NOMESCO Finland
Graft of patients own bone
6.1
10.0
26
43
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
40.2
10.0
12
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
9.9
569
4329
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
9.8
1038
8666
J01FA06
ATC
roxithromycin; oral
1.3
9.8
1017
8474
A02BC01
ATC
omeprazole; systemic
1.4
9.7
633
4920
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
1.8
9.7
153
849
M02AA07
ATC
piroxicam; topical
1.3
9.7
857
6981
L15
ICPC
Knee symptom/complaint
1.4
9.5
478
3550
A02BC03
ATC
lansoprazole; oral
1.3
9.5
690
5453
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.5
525
3967
J01CA04
ATC
amoxicillin; systemic
1.3
9.4
2290
21251
S62.6
ICD-10 Finland
Fracture of other finger
2.0
9.4
117
596
NHR99
NOMESCO Finland
Other operation for tumour of ankle or foot
30.1
9.4
12
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.4
412
2982
L13
ICPC
Hip symptom/complaint
1.5
9.4
331
2295
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
9.2
142
786
UJF32
NOMESCO Finland
Coloscopy
1.4
9.1
578
4471
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
6.3
9.1
23
37
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.0
1057
8925
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
2.5
9.0
70
289
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
3.2
9.0
44
137
M12.2
ICD-10 Finland
Villonodular synovitis (pigmented)
18.6
8.9
13
7
M89.3
ICD-10 Finland
Hypertrophy of bone
18.6
8.9
13
7
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
8.9
1561
13848
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.8
8.9
137
759
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
8.8
696
5564
B01AB05
ATC
enoxaparin; parenteral
1.3
8.7
678
5407
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.6
8.7
220
1409
R93.7
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
14.1
8.7
14
10
N02AA05
ATC
oxycodone; systemic
1.5
8.7
277
1876
M01AC06
ATC
meloxicam; systemic, rectal
1.3
8.7
886
7340
H02AB06
ATC
prednisolone; systemic
1.3
8.6
1143
9785
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.6
8.6
247
1628
M85.0
ICD-10 Finland
Fibrous dysplasia (monostotic)
16.3
8.5
13
8
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.1
8.5
92
443
E0000UV
ATC
NA
1.3
8.5
996
8397
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
8.5
610
4802
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
8.4
393
2882
D16.9
ICD-10 Finland
Benign neoplasm: Bone and articular cartilage, unspecified
+∞
8.3
8
*
D16.4
ICD-10 Finland
Benign neoplasm: Bones of skull and face
+∞
8.3
8
*
XKD00
NOMESCO Finland
Uroflowmetry
1.5
8.3
293
2031
ND2CG
NOMESCO Finland
Extensive MRI of hand
8.5
8.3
17
20
R53
ICD-10 Finland
Malaise and fatigue
1.4
8.2
465
3525
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
8.2
1188
10268
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
14.5
8.2
13
9
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
7.5
8.1
18
24
M16.1
ICD-10 Finland
Other primary coxarthrosis
1.6
8.1
217
1412
NDR99
NOMESCO Finland
Other operation for tumour of wrist or hand
33.4
8.1
10
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
11.7
8.1
14
12
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
1.8
8.0
139
800
TAKUU
NOMESCO Finland
NA
3.8
8.0
32
85
NHR30
NOMESCO Finland
Complete excision of soft tissue tumour of ankle or foot
22.1
8.0
11
5
J02AC01
ATC
fluconazole; systemic
1.3
8.0
1025
8722
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
8.0
238
1589
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
7.9
473
3613
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.9
388
2865
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
7.9
243
1636
ZZH31
NOMESCO Finland
Bone allograft, small pieces
4.5
7.9
26
58
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
2.5
7.8
58
234
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
7.8
633
5067
M48.0
ICD-10 Finland
Spinal stenosis
1.5
7.8
239
1604
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.8
7.7
129
732
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.5
7.7
252
1717
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.6
7.7
219
1441
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
7.7
164
1005
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
2.8
7.7
47
171
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
7.7
754
6196
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
7.7
303
2150
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.6
1553
13916
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.6
7.5
172
1075
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.5
663
5369
G44.2
ICD-10 Finland
Tension-type headache
1.4
7.5
319
2293
ND3CG
NOMESCO Finland
Extensive MRI of fingers
10.0
7.5
14
14
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
7.5
259
1784
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
2.7
7.5
49
186
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.7
7.4
141
836
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
80.3
7.4
8
*
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
80.3
7.4
8
*
NGR99
NOMESCO Finland
Other operation for tumour of knee or lower leg
80.3
7.4
8
*
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.7
7.4
142
842
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
1.7
7.3
152
926
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.3
983
8391
D16.91
ICD-10 Finland
Benign tumor in unspecified localization in bone with urpsrung in teeth
+∞
7.3
7
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
2.2
7.3
72
337
9166
FHL
Bone graft to promote ossification
9.4
7.3
14
15
R06AE07
ATC
cetirizine; oral
1.2
7.3
1138
9884
Q78.1
ICD-10 Finland
Polyostotic fibrous dysplasia
30.1
7.1
9
*
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
20.1
7.1
10
5
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
7.0
239
1641
A02BA02
ATC
ranitidine; systemic
1.4
7.0
425
3256
L17
ICPC
Foot/toe symptom/complaint
1.3
7.0
562
4492
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
6.9
295
2120
WX002
NOMESCO Finland
Sedation and analgesia
1.4
6.9
434
3337
L16
ICPC
Ankle symptom/complaint
1.5
6.9
235
1616
R06.0
ICD-10 Finland
Dyspnoea
1.3
6.9
531
4213
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
6.9
246
1706
L12
ICPC
Hand/finger symptom/complaint
1.4
6.9
325
2385
J20
ICD-10 Finland
Acute bronchitis
1.5
6.9
214
1446
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.6
6.8
163
1028
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.1
6.8
71
341
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
3.0
6.8
36
121
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
40.1
6.8
8
*
9105
FHL
Homogeneous or heterogeneous bone graft, e.g., joint graft
40.1
6.8
8
*
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.7
978
8405
EBB10
NOMESCO Finland
Insertion of dental implant
3.0
6.7
36
122
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
6.6
186
1225
M85.8
ICD-10 Finland
Other specified disorders of bone density and structure
5.5
6.6
18
33
NCR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of elbow or forearm
12.3
6.6
11
9
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.7
6.5
124
737
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
6.5
651
5345
NE1CM
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with 3 Tesla magnet
10.0
6.5
12
12
WZA90
NOMESCO Finland
Other doctors statement
1.3
6.5
567
4576
H02AB04
ATC
methylprednisolone; systemic
1.4
6.5
329
2441
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.5
665
5479
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.9
6.5
94
514
-
ICD-10 Finland
NA
2.3
6.4
55
240
M79.1
ICD-10 Finland
Myalgia
1.4
6.4
300
2196
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.4
898
7679
R50.9
ICD-10 Finland
Fever, unspecified
1.4
6.4
312
2304
F45.8
ICD-10 Finland
Other somatoform disorders
1.6
6.4
174
1136
SPAT1312
SPAT
General health counselling
1.3
6.4
792
6679
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.2
6.4
60
274
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.8
6.4
110
635
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
3.9
6.4
24
62
N06AA09
ATC
amitriptyline; systemic
1.5
6.3
219
1514
M01AH03
ATC
valdecoxib; oral
1.6
6.3
145
910
EDB00
NOMESCO Finland
Partial excision of mandible
11.0
6.3
11
10
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
2.0
6.3
78
402
ND1CM
NOMESCO Finland
Wrist and hand extensive MRI examination with 3 Tesla magnet
9.3
6.3
12
13
EEB00
NOMESCO Finland
Partial excision of maxilla
18.0
6.3
9
5
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
18.0
6.3
9
5
D07AC01
ATC
betamethasone; topical
1.2
6.3
797
6736
WX203
NOMESCO Finland
Infraclavicular plexus blockade
2.2
6.3
59
270
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
6.2
6
*
4332
FHL
Lower jaw resection or tumor removal
+∞
6.2
6
*
2132A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Vertebral column, excluding sacrum and coccyx
+∞
6.2
6
*
4339
FHL
Other measure in this category
+∞
6.2
6
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
6.2
720
6017
1220
FHL
Arthroscopy
1.8
6.2
92
505
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
26.7
6.2
8
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
26.7
6.2
8
*
ZXD20
NOMESCO Finland
Day surgery
1.4
6.2
304
2244
WX290
NOMESCO Finland
Other blockade of nerve
1.2
6.2
1186
10475
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.6
6.1
151
964
J02AC02
ATC
itraconazole; systemic
1.3
6.1
406
3154
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
6.1
327
2453
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
6.1
345
2612
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.6
6.0
147
937
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.3
6.0
530
4280
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
6.7
6.0
14
21
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BONE_CARTILAGE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_CARTILAGE | 1.057 [0.93, 1.21] | 0.407 |
| Birth year | 0.999 [0.99, 1.01] | 0.714 |
During the follow-up period (1.1.1998 — 31.12.2019), 530 out of 7903 females with CD2_BENIGN_BONE_CARTILAGE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_CARTILAGE | 1.056 [0.93, 1.2] | 0.408 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 589 out of 7613 males with CD2_BENIGN_BONE_CARTILAGE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BONE_CARTILAGE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.093% | 0.165% |
| 5 | 0.603% | 1.185% |
| 10 | 1.661% | 2.905% |
| 15 | 3.341% | 5.841% |
| 20 | 6.078% | 9.778% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BONE_CARTILAGE – Benign neoplasm of bone and articular cartilage
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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