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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_THYROID_FOLLICULAR_EXALLC for full statistics.

Follicular adenocarcinoma of thyroid gland

C3_THYROID_FOLLICULAR

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C73.92&
  • Cause of death: ICD-9 193B
  • Cancer registry: Topography ICD-O-3 C73
  • Cancer registry: Morphology ICD-O-3 833[0-2]|8335
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

204

4. Check minimum number of events

None

204

5. Include endpoints

None

204

6. Filter based on genotype QC (FinnGen only)

195

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 195 120 75
Unadjusted period prevalence (%) 0.04 0.05 0.04
Median age at first event (years) 50.33 47.16 55.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
204
Matched controls
2040
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
+∞
268.8
194
*
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
11335.3
228.0
175
*
104
Kela drug reimbursment
Thyroid insufficiency
69.1
129.0
156
91
H03AA01
ATC
levothyroxine sodium; systemic
90.0
118.9
193
332
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
142.3
104.3
105
15
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
250.3
80.7
78
5
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
275.8
74.7
72
*
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
509.5
72.5
68
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
28.9
69.2
98
63
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
126.1
59.9
62
7
BAA60
NOMESCO Finland
Total thyroidectomy
47.6
46.5
56
16
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
67.4
45.2
51
10
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
37.7
35
*
ZX114
NOMESCO Finland
Intramuscular
79.7
35.4
39
6
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
380.6
32.9
32
*
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
40.4
27.5
34
10
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
13.6
23.8
42
38
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.4
22.2
119
490
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
245.2
22.0
22
*
4CJ01
NOMESCO Finland
NA
245.2
22.0
22
*
19399
ICD-8 Finland
Malignant neoplasm of thyroid gland
+∞
20.1
19
*
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
220.5
19.9
20
*
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
196.3
17.8
18
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
17.1
14.8
23
15
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
14.9
14.6
24
18
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
36.9
13.7
17
5
1930B
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA FOLLICULARE THYREOIDEAE]
+∞
12.6
12
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
16.3
11.5
18
12
Z51.88
ICD-10 Finland
Other specified medical care
12.2
11.3
20
18
8335/3-C73.9
ICD-O-3
Follicular carcinoma, minimally invasive of thyroid gland
+∞
10.5
10
*
WW200
NOMESCO Finland
Immunization
9.9
9.8
19
21
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
+∞
9.4
9
*
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
38.5
9.1
11
*
106
Kela drug reimbursment
Hypoparathyroidism
93.8
8.5
9
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.5
8.2
86
462
WB223
NOMESCO Finland
Demanding adjuvant hormone therapy of malignancy
34.9
8.2
10
*
2506
FHL
Thyroidectomy
83.0
7.5
8
*
JN5SN
NOMESCO Finland
NA
83.0
7.5
8
*
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
31.2
7.2
9
*
WX402
NOMESCO Finland
General anaesthesia
2.8
6.7
44
180
WF049
NOMESCO Finland
Radiotherapy of metastasis
7.8
6.5
14
19
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
72.0
6.5
7
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
11.5
6.4
11
10
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
+∞
6.3
6
*
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
9.0
6.1
12
14

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_THYROID_FOLLICULAR – Follicular adenocarcinoma of thyroid gland

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).