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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_SALIVARYNAS_EXALLC for full statistics.

Malignant neoplasm of other and unspecified major salivary glands

C3_SALIVARYNAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C08
  • Cause of death: ICD-9 142
  • Cause of death: ICD-8 142
  • Cause of death: excluded ICD-9 1420
  • Cancer registry: Topography ICD-O-3 C08
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

101

4. Check minimum number of events

None

101

5. Include endpoints

None

101

6. Filter based on genotype QC (FinnGen only)

97

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 97 48 49
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 65.29 64.58 65.98

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
101
Matched controls
1008
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ELB30
NOMESCO Finland
Excision of submandibular gland
+∞
46.5
41
*
C08.09
ICD-10 Finland
Malignant tumor of the submandibular or submaxillary gland, other or unspecified histology
+∞
34.3
31
*
D11.70
ICD-10 Finland
Gland sublingual
+∞
33.1
30
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
293.7
23.7
23
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
28.6
23.6
32
16
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
32.1
23.0
30
13
C08.02
ICD-10 Finland
Cystic adenocarcinoma of the submandibular or submaxillary glands
+∞
21.6
20
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
21.6
20
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
24.5
21.2
30
17
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
7.9
20.6
69
216
8200/3-C08.0
ICD-O-3
Adenoid cystic carcinoma of submandibular gland
+∞
19.4
18
*
C08.00
ICD-10 Finland
Malignant tumor of submandibular or submaxillary gland, not histology
+∞
16.0
15
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
94.1
15.0
16
*
D37.00
ICD-10 Finland
Aryepiglottic fold marginal zone
+∞
14.9
14
*
XX3DW
NOMESCO Finland
Time consuming IT work
8.9
14.6
33
52
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
35.9
14.4
18
6
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
40.3
14.0
17
5
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
147.4
12.7
13
*
130
Kela drug reimbursment
Malignant tumour
7.6
12.1
30
53
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
73.7
11.9
13
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
12.7
10.8
19
18
C08.90
ICD-10 Finland
Malignant tumor in unspecified large salivary gland without histology
+∞
10.6
10
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
33.6
9.6
12
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
109.8
9.6
10
*
C08.0
ICD-10 Finland
Malignant neoplasm: Submandibular gland
+∞
9.5
9
*
C08.01
ICD-10 Finland
Diverse adenocarcinoma of the mandibular salivary gland
+∞
9.5
9
*
SAA03
NOMESCO Finland
Extended examination of mouth
3.7
9.2
57
259
A07AA02
ATC
nystatin; oral
8.4
8.8
19
27
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.1
8.6
24
49
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
97.8
8.5
9
*
N02AA05
ATC
oxycodone; systemic
4.6
8.5
32
92
9699/3-C08.0
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of submandibular gland
+∞
8.4
8
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
19.2
8.3
12
7
WF049
NOMESCO Finland
Radiotherapy of metastasis
14.7
8.1
13
10
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.3
7.8
57
282
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
48.9
7.8
9
*
XW000
NOMESCO Finland
Bone marrow biopsy
13.3
7.8
13
11
Z51.5
ICD-10 Finland
Palliative care
6.8
7.7
19
33
EL4AT
NOMESCO Finland
Salivary gland cytology with ultrasound guidance
+∞
7.4
7
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
7.4
7
*
8430/3-C08.0
ICD-O-3
Mucoepidermoid carcinoma of submandibular gland
+∞
7.4
7
*
8200/3-C08.9
ICD-O-3
Adenoid cystic carcinoma of major salivary gland, NOS
+∞
7.4
7
*
C08.94
ICD-10 Finland
Mucoepidermoid carcinoma of an unspecified large salivary gland
+∞
7.4
7
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
13.4
7.3
12
10
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
32.5
7.3
9
*
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
43.0
6.9
8
*
JN6AD
NOMESCO Finland
CT of torso and neck
43.0
6.9
8
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
13.5
6.8
11
9
EHB00
NOMESCO Finland
Excision of lesion of palate
+∞
6.3
6
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C08.91
ICD-10 Finland
Adenocarcinoma of mixed cell type in unspecified large salivary gland
+∞
6.3
6
*
EJB30
NOMESCO Finland
Excision of lesion of floor of mouth
+∞
6.3
6
*
C08.9
ICD-10 Finland
Malignant neoplasm: Major salivary gland, unspecified
+∞
6.3
6
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
8.9
6.0
12
15

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_SALIVARYNAS – Malignant neoplasm of other and unspecified major salivary glands

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).