≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback
info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Retinoblastoma, excluding all cancers (controls excluding all cancers)

Endpoint Browser

C3_RETINOBLAST_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C69.21&, C69.81&, C69.91&
  • Cause of death: ICD-10 — C69.21&, C69.81&, C69.91&
  • Cancer registry: Topography ICD-O-3 — C69
  • Cancer registry: Morphology ICD-O-3 — 951[0-4]
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

30

4. Check minimum number of events

None

30

5. Include endpoints

None

30

6. Filter based on genotype QC (FinnGen only)

30

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

↥

List of similar endpoints to Retinoblastoma, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 30 18 12
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 2.54 2.66 2.36

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(42870588) Differential panel, method unspecified - Blood
21
84
5.96
4.89
17.2
6.3
—
—
—
0
0
(4035726)
7
5
17.58
4.83
1.9
1.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
17
70
4.30
3.72
3.4
1.5
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
7
11
7.90
3.40
4.1
30.5
%
97.4
94.5
—
7
11
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
6
8
9.00
3.21
4.7
2.5
%
160.5
198.9
—
6
8
(3044640) Blood type and Crossmatch panel - Blood
14
55
3.90
3.18
7.4
3.7
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
13
50
3.82
3.01
10.8
7.9
%
90.8
93.3
0.11
13
50
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
7
8.26
2.65
1.6
1.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
11
41
3.66
2.62
7.5
4.2
—
—
—
0
0
(3020779) Urea [Moles/volume] in Serum or Plasma
7
17
5.03
2.53
11.6
20.1
mmol/l
5.2
6.9
—
7
17
(3022948) Iron [Moles/volume] in Serum or Plasma
8
23
4.35
2.48
4.5
3.4
umol/l
14.4
13.7
—
8
23
(3020630) Protein [Mass/volume] in Serum or Plasma
5
8
7.21
2.47
24.4
1.0
g/l
62.2
63.9
—
5
8
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
8
7.21
2.47
1.4
1.1
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
8
24
4.15
2.38
1.6
1.5
—
360.0
—
0
6
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
15
72
3.17
2.38
3.6
2.9
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
5
10
5.74
2.16
1.2
1.4
—
—
—
0
0
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
5
10
5.74
2.16
5.2
12.9
g/l
3.7
3.7
—
5
10
(3002256) Pathology report gross observation
7
21
4.02
2.11
1.3
1.3
—
—
—
0
0
(3019225) pH of Specimen
6
16
4.41
2.05
7.0
3.6
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
7
22
3.82
2.02
2.9
3.5
g/l
6.9
10.0
—
7
22
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
16
87
2.80
1.95
6.8
5.8
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
7
23
3.64
1.94
1.4
1.7
u/ml
21.8
129.4
—
7
23
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
8
32
3.03
1.75
1.3
1.7
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
15
85
2.53
1.62
3.0
2.4
nmol/l
82.9
71.7
0.78
15
76
(3021589) Normoblasts [#/volume] in Blood
18
112
2.52
1.59
23.1
6.8
e9/l
0.0
0.0
0.00
13
83
(3023368) Bacteria identified in Blood by Culture
9
41
2.70
1.54
5.6
5.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
12
64
2.46
1.43
3.7
2.7
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
21
154
2.21
1.25
7.2
3.6
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
5
21
2.65
1.13
2.0
1.1
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
5
22
2.52
1.07
2.2
5.5
—
—
—
0
0
(40758558) Short blood count panel - Blood
11
66
2.05
0.95
34.8
6.4
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
6
32
2.09
0.87
30.2
5.8
kpa
5.8
5.9
—
6
32
(3012544) pH of Venous blood
6
33
2.02
0.84
29.8
6.2
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
24
200
2.00
0.81
6.7
4.2
mmol/mol
36.7
38.4
0.47
24
186
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
5
23
2.40
0.80
34.6
7.0
mmol/l
24.2
24.2
—
5
23
(3022313) Gas panel - Capillary blood
5
23
2.40
0.80
8.2
18.6
—
—
—
0
0
(3013512) EKG study
7
41
1.92
0.76
4.0
2.1
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
5
26
2.10
0.74
3.4
2.8
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
25
211
2.10
0.70
4.1
3.4
mmol/l
1.4
1.2
0.52
25
194
(3024354) Oxygen [Partial pressure] in Venous blood
5
28
1.94
0.69
33.8
4.7
kpa
4.8
4.8
—
5
28
(3015736) pH of Urine
13
91
1.76
0.68
4.8
2.3
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
8
51
1.77
0.68
1.6
1.8
—
—
—
0
0
(3000991) Gas panel - Venous blood
5
29
1.86
0.67
36.2
11.6
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
30
281
+∞
0.63
45.5
16.0
e9/l
6.8
6.7
0.04
30
271
(3000963) Hemoglobin [Mass/volume] in Blood
30
281
+∞
0.63
46.6
16.0
g/l
134.7
136.7
0.30
30
275
(3035941) MCH [Entitic mass]
30
281
+∞
0.63
45.2
15.9
pg
30.5
29.7
1.66
30
275
(3026361) Erythrocytes [#/volume] in Blood
30
281
+∞
0.63
45.4
16.0
e12/l
4.5
4.6
0.70
30
271
(3007461) Platelets [#/volume] in Blood
30
281
+∞
0.63
45.3
16.0
e9/l
260.7
266.1
0.18
30
271
(3024731) MCV [Entitic volume]
30
281
+∞
0.63
45.2
15.9
fl
90.3
88.7
0.85
30
275
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
0
19
0.00
0.63
0.0
1.0
—
4.5
—
0
11
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
19
0.00
0.63
0.0
1.3
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
20
165
1.64
0.52
6.2
3.5
u/l
33.8
35.4
0.10
20
157
(3001122) Ferritin [Mass/volume] in Serum or Plasma
15
117
1.56
0.48
5.3
3.0
ug/l
95.3
79.5
0.24
15
110
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
9
67
1.49
0.44
1.6
1.7
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
25
222
1.75
0.42
4.8
3.5
mmol/l
1.4
1.5
0.24
25
203
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
25
225
1.66
0.42
5.0
3.6
mmol/l
3.2
2.8
0.78
25
206
(3003888) Timothy IgE Ab [Units/volume] in Serum
0
16
0.00
0.42
0.0
1.0
—
9.0
—
0
10
(3008401) Mugwort IgE Ab [Units/volume] in Serum
0
16
0.00
0.42
0.0
1.0
—
5.4
—
0
11
(3025941) Bacteria identified in Stool by Culture
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
(3010726) Horse dander IgE Ab [Units/volume] in Serum
0
16
0.00
0.42
0.0
1.1
—
0.0
—
0
5
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
42
1.53
0.38
1.5
2.2
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
46
1.38
0.35
1.7
2.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
7
53
1.42
0.34
1.1
1.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
8
61
1.42
0.32
4.5
2.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
8
65
1.31
0.30
3.0
2.1
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
15
127
1.36
0.27
15.4
8.8
mmol/l
6.1
6.3
0.21
15
112
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.22
0.0
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
11
0.00
0.22
0.0
1.6
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
10
0.00
0.22
0.0
1.7
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
10
0.00
0.22
0.0
2.0
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
10
0.00
0.22
0.0
1.7
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
0
10
0.00
0.22
0.0
2.0
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
10
0.00
0.22
0.0
1.1
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
0
10
0.00
0.22
0.0
1.0
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
7
56
1.32
0.20
5.9
2.2
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
7
59
1.24
0.20
2.0
2.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
8
66
1.29
0.19
1.3
1.4
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
7
62
1.17
0.09
23.4
3.7
—
—
—
0
0
(3003338) MCHC [Mass/volume]
23
235
0.91
0.09
40.7
14.8
g/l
335.9
334.4
0.44
23
235
(3019550) Sodium [Moles/volume] in Serum or Plasma
24
229
1.24
0.09
42.4
13.8
mmol/l
139.6
139.6
0.01
24
217
(3023103) Potassium [Moles/volume] in Serum or Plasma
24
232
1.17
0.08
42.1
13.8
mmol/l
3.9
4.0
0.29
24
219
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
9
83
1.12
0.08
5.9
2.3
—
—
—
0
0
(3044889) 12 lead EKG panel
14
134
1.08
0.01
4.5
3.0
—
—
—
0
0
(3020891) Body temperature
0
8
0.00
0.00
0.0
4.4
—
—
—
0
0
(3028271) Lactate [Moles/volume] in Capillary blood
0
5
0.00
0.00
0.0
1.8
—
1.5
—
0
5
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001684) Respiratory syncytial virus Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019060) Gas panel - Arterial blood
0
6
0.00
0.00
0.0
82.0
—
—
—
0
0
(3007566) Smooth muscle Ab [Titer] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
0
5
0.00
0.00
0.0
2.8
—
9.2
—
0
5
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
0
5
0.00
0.00
0.0
2.8
—
4.8
—
0
5
(1761868) Lipid panel - Serum or Plasma
9
89
1.02
0.00
2.3
2.2
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
8
87
0.89
0.00
2.3
1.9
—
—
—
0
0
(3010421) pH of Blood
0
5
0.00
0.00
0.0
2.8
—
7.5
—
0
5
(40768443) Skin Pathology biopsy report
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4034850)
0
7
0.00
0.00
0.0
8.9
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
23
233
0.94
0.00
3.5
4.1
—
—
—
0
0
(3005082) Progesterone [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
26.0
—
0
5

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_RETINOBLAST_EXALLC – Retinoblastoma, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).