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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_PAROTIDGLAND_EXALLC for full statistics.

Malignant neoplasm of parotid gland

C3_PAROTIDGLAND

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C07
  • Cause of death: ICD-9 1420
  • Cause of death: ICD-8 1420
  • Cancer registry: Topography ICD-O-3 C07
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

249

4. Check minimum number of events

None

249

5. Include endpoints

None

249

6. Filter based on genotype QC (FinnGen only)

239

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 239 116 123
Unadjusted period prevalence (%) 0.05 0.05 0.06
Median age at first event (years) 62.06 59.60 64.37

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
249
Matched controls
2490
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C07.70
ICD-10 Finland
Malignant tumor of the superficial part of the parotid gland
+∞
169.9
143
*
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
248.9
163.6
154
16
ELB50
NOMESCO Finland
Total parotidectomy
1545.0
106.5
96
*
ELB40
NOMESCO Finland
Partial parotidectomy
271.8
103.1
99
6
EP1AE
NOMESCO Finland
Neck ultrasound examination
18.5
49.7
80
62
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
140.3
44.4
46
*
8550/3-C07.9
ICD-O-3
Acinar cell carcinoma of parotid gland
+∞
43.0
40
*
C07.71
ICD-10 Finland
Malignant tumor in the deep part of the parotid gland
+∞
40.8
38
*
D37.00
ICD-10 Finland
Aryepiglottic fold marginal zone
158.0
39.0
40
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
17.7
36.2
58
42
8430/3-C07.9
ICD-O-3
Mucoepidermoid carcinoma of parotid gland
+∞
29.8
28
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
17.8
29.7
47
32
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
44.9
28.9
35
9
C08.89
ICD-10 Finland
Malignant overall tumor the large salivary glands anna or unspecified histology
+∞
25.4
24
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.3
23.3
113
402
8070/3-C07.9
ICD-O-3
Squamous cell carcinoma, NOS, of parotid gland
+∞
22.2
21
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
27.1
21.4
29
12
8500/3-C07.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of parotid gland
+∞
21.1
20
*
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
120.1
20.9
22
*
G51.0
ICD-10 Finland
Bell palsy
21.1
20.5
30
16
C07
ICD-10 Finland
Malignant neoplasm of parotid gland
+∞
20.1
19
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
44.1
19.9
24
6
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
57.0
18.3
21
*
ELB00
NOMESCO Finland
Excision or exploration of lesion of salivary gland
193.2
17.8
18
*
8200/3-C07.9
ICD-O-3
Adenoid cystic carcinoma of parotid gland
+∞
16.9
16
*
C08.99
ICD-10 Finland
Malignant tumor of unspecified large salivary gland, other or unspecified histology
+∞
16.9
16
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.2
16.3
116
529
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
90.9
15.8
17
*
9699/3-C07.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of parotid gland
+∞
14.7
14
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
32.2
14.1
18
6
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
36.3
13.7
17
5
130
Kela drug reimbursment
Malignant tumour
4.6
13.6
50
129
A03FA01
ATC
metoclopramide; systemic, rectal
3.2
13.0
83
338
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
6.1
12.7
35
65
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
28.3
12.2
16
6
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
12.6
12.1
21
18
8140/3-C07.9
ICD-O-3
Adenocarcinoma, NOS, of parotid gland
+∞
11.5
11
*
8562/3-C07.9
ICD-O-3
Epithelial-myoepithelial carcinoma of parotid gland
+∞
11.5
11
*
SAA03
NOMESCO Finland
Extended examination of mouth
2.7
11.5
108
554
EL4AT
NOMESCO Finland
Salivary gland cytology with ultrasound guidance
45.5
11.0
13
*
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
9.2
10.8
22
26
AAH50
NOMESCO Finland
Cranial nerve anastomosis
+∞
10.5
10
*
C08.94
ICD-10 Finland
Mucoepidermoid carcinoma of an unspecified large salivary gland
+∞
10.5
10
*
XX3DW
NOMESCO Finland
Time consuming IT work
3.6
10.4
49
157
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
6.1
10.3
28
51
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.2
10.1
31
66
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
17.6
10.0
15
9
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
7.1
9.7
23
35
EBA15
NOMESCO Finland
Extraction of large number of teeth
6.7
9.7
24
39
9691/3-C07.9
ICD-O-3
Follicular lymphoma, grade 2 of parotid gland
+∞
9.4
9
*
9591/3-C07.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of parotid gland
+∞
9.4
9
*
8010/3-C07.9
ICD-O-3
Carcinoma, NOS, of parotid gland
+∞
9.4
9
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
9.4
9
*
9680/3-C07.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of parotid gland
+∞
9.4
9
*
DEB00
NOMESCO Finland
Cortical mastoidectomy
+∞
9.4
9
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
8.3
9.3
20
26
UDC00
NOMESCO Finland
Ear microscopy
4.4
9.3
34
87
WF002
NOMESCO Finland
Radical radiotherapy
4.9
9.0
29
65
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
9.0
53
198
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.5
8.9
43
141
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
51.9
8.7
10
*
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
12.2
8.7
15
13
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
10.6
8.7
16
16
ED1AA
NOMESCO Finland
Mandipular X-ray examination
28.6
8.6
11
*
H02.2
ICD-10 Finland
Lagophthalmos
28.6
8.6
11
*
4405
FHL
Partial removal of the parotid gland
93.1
8.5
9
*
8941/3-C07.9
ICD-O-3
Carcinoma ex pleomorphic adenoma of parotid gland
+∞
8.4
8
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
+∞
8.4
8
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.4
8.3
42
142
WX110
NOMESCO Finland
Local anesthesy
2.3
8.3
173
1252
S04
ICPC
Lump/swelling localized
3.6
8.3
37
114
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
8.2
112
669
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
17.9
8.2
12
7
EL3AE
NOMESCO Finland
Salivary gland ultrasound examination
17.9
8.2
12
7
R4190
NOMESCO Finland
Nutritional therapy
5.8
8.1
22
41
ZX090
NOMESCO Finland
Other technic of radiotherapy
6.5
8.0
20
33
ZXE40
NOMESCO Finland
More than seven and less than nine hours
8.9
7.9
16
19
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
11.3
7.9
14
13
WX402
NOMESCO Finland
General anaesthesia
2.8
7.9
54
222
C82.1
ICD-10 Finland
Follicular lymphoma grade II
46.5
7.8
9
*
8502/3-C07.9
ICD-O-3
Secretory carcinoma of parotid gland
+∞
7.3
7
*
SCA04
NOMESCO Finland
Guidance on care of mouth and oral mucosa
+∞
7.3
7
*
8147/3-C07.9
ICD-O-3
Basal cell adenocarcinoma of parotid gland
+∞
7.3
7
*
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
16.4
7.3
11
7
K05.30
ICD-10 Finland
Periodontitis complex
3.0
7.2
42
157
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
31.0
7.2
9
*
EBA10
NOMESCO Finland
Surgical removal of tooth
3.3
7.1
36
122
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
6.9
105
645
A07AA02
ATC
nystatin; oral
3.5
6.8
31
97
K11.2
ICD-10 Finland
Sialoadenitis
7.5
6.8
15
21
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.4
6.7
23
56
XW000
NOMESCO Finland
Bone marrow biopsy
4.5
6.6
22
52
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
10.4
6.6
12
12
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
71.6
6.5
7
*
ELB60
NOMESCO Finland
Radical parotidectomy sacrificing the facial nerve
71.6
6.5
7
*
4404
FHL
Complete removal of the parotid gland
71.6
6.5
7
*
UJC01
NOMESCO Finland
Scopy of lower throat
14.8
6.4
10
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
6.4
118
777
EMB10
NOMESCO Finland
Tonsillectomy
5.3
6.3
18
36
S18
ICPC
Laceration/cut
2.0
6.3
111
715
C08.90
ICD-10 Finland
Malignant tumor in unspecified large salivary gland without histology
+∞
6.3
6
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
10.4
6.1
11
11
WF049
NOMESCO Finland
Radiotherapy of metastasis
4.5
6.1
20
47

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_PAROTIDGLAND – Malignant neoplasm of parotid gland

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).