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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_NASOPHARYNX_EXALLC for full statistics.

Malignant neoplasm of nasopharynx

C3_NASOPHARYNX

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C11
  • Cause of death: ICD-9 147
  • Cause of death: ICD-8 147
  • Cancer registry: Topography ICD-O-3 C11
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

96

4. Check minimum number of events

None

96

5. Include endpoints

None

96

6. Filter based on genotype QC (FinnGen only)

89

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 89 38 51
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 62.14 57.12 65.88

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
96
Matched controls
961
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UDH02
NOMESCO Finland
Rhinopharyngoscopy
57.9
44.5
52
19
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
183.0
42.9
42
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
214.9
40.2
39
*
8070/3-C11.9
ICD-O-3
Squamous cell carcinoma, NOS, of nasopharynx, NOS
+∞
35.7
32
*
C11.9
ICD-10 Finland
Malignant neoplasm: Nasopharynx, unspecified
+∞
32.1
29
*
130
Kela drug reimbursment
Malignant tumour
19.2
31.8
54
60
A03FA01
ATC
metoclopramide; systemic, rectal
11.4
25.5
61
127
EMA30
NOMESCO Finland
Biopsy of rhinopharynx
+∞
23.9
22
*
C11.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of nasopharynx
+∞
22.8
21
*
WF002
NOMESCO Finland
Radical radiotherapy
17.5
21.0
34
29
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
8.2
20.3
63
180
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
22.5
19.9
29
18
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
62.3
17.8
20
*
C11.1
ICD-10 Finland
Malignant neoplasm: Posterior wall of nasopharynx
+∞
17.2
16
*
C11.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of nasopharynx
+∞
17.2
16
*
C11.0
ICD-10 Finland
Malignant neoplasm: Superior wall of nasopharynx
+∞
17.2
16
*
D10.6
ICD-10 Finland
Benign neoplasm: Nasopharynx
+∞
17.2
16
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
35.5
15.9
20
7
N02AA05
ATC
oxycodone; systemic
7.4
15.6
43
94
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
19.7
15.4
23
15
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
43.7
15.1
18
5
UDQ12
NOMESCO Finland
Flexible laryngoscopy
11.9
14.8
28
32
EP1AE
NOMESCO Finland
Neck ultrasound examination
17.4
14.1
22
16
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
87.6
14.0
15
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
162.0
13.8
14
*
EBA10
NOMESCO Finland
Surgical removal of tooth
9.9
13.5
28
38
A04AA01
ATC
ondansetron; systemic, rectal
11.2
13.0
25
29
H65.2
ICD-10 Finland
Chronic serous otitis media
37.9
13.0
16
5
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
148.6
12.8
13
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
6.3
11.1
32
70
A04AA02
ATC
granisetron; systemic, transdermal
8.8
10.6
23
33
8010/3-C11.9
ICD-O-3
Carcinoma, NOS, of nasopharynx, NOS
+∞
10.6
10
*
A07AA02
ATC
nystatin; oral
9.8
10.0
20
25
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
7.1
10.0
25
45
H02AB02
ATC
dexamethasone; systemic
5.8
9.8
30
70
XX3DW
NOMESCO Finland
Time consuming IT work
6.2
9.8
28
60
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
33.9
9.7
12
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
110.5
9.6
10
*
DHA10
NOMESCO Finland
Biopsy of cavity of nose
110.5
9.6
10
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
10.8
9.5
18
20
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
9.5
9
*
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
9.5
9
*
WX199
NOMESCO Finland
Other local analgesia
21.2
9.2
13
7
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.8
8.7
52
229
UDM02
NOMESCO Finland
Sinoscopy
22.5
8.7
12
6
H65.3
ICD-10 Finland
Chronic mucoid otitis media
22.5
8.7
12
6
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
9.6
8.5
17
21
9680/3-C11.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of nasopharynx, NOS
+∞
8.4
8
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
8.4
8
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
19.3
8.3
12
7
K11.71
ICD-10 Finland
Xerostomy (dry mouth)
36.8
8.3
10
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
36.8
8.3
10
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
9.9
8.2
16
19
R13
ICD-10 Finland
Dysphagia
7.7
7.9
18
28
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.7
7.9
18
28
ENA10
NOMESCO Finland
Biopsy of pharynx
86.5
7.5
8
*
8070/3-C11.2
ICD-O-3
Squamous cell carcinoma, NOS, of lateral wall of nasopharynx
+∞
7.4
7
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
13.5
7.3
12
10
J01CE02
ATC
phenoxymethylpenicillin; oral
3.6
6.9
77
506
A01AB09
ATC
miconazole; local oral
6.1
6.7
18
35
H66.0
ICD-10 Finland
Acute suppurative otitis media
8.4
6.7
14
19
WF003
NOMESCO Finland
Adjuvant radiotherapy
9.2
6.6
13
16
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
15.7
6.6
10
7
SAA03
NOMESCO Finland
Extended examination of mouth
3.2
6.5
45
209
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
74.6
6.5
7
*
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
19.6
6.4
9
5
8070/3-C11.1
ICD-O-3
Squamous cell carcinoma, NOS, of posterior wall of nasopharynx
+∞
6.3
6
*
8072/3-C11.9
ICD-O-3
Squamous cell carcinoma, large cell, nonkeratinizing, NOS, of nasopharynx, NOS
+∞
6.3
6
*
SXC05
NOMESCO Finland
Other oral or dental procedure
9.6
6.3
12
14
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
16.3
6.0
9
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_NASOPHARYNX – Malignant neoplasm of nasopharynx

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).