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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_CML_EXALLC for full statistics.

Chronic myeloid leukaemia

C3_CML

obsolete_chronic myeloid leukemia: ['Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.']

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C92.1
  • Cause of death: ICD-9 2051A
  • Cause of death: ICD-8 20515
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9863|9875
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

143

4. Check minimum number of events

None

143

5. Include endpoints

None

143

6. Filter based on genotype QC (FinnGen only)

143

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 143 59 84
Unadjusted period prevalence (%) 0.03 0.02 0.04
Median age at first event (years) 57.92 54.96 60.00

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
142
Matched controls
1420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
201.9
141
*
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
+∞
164.1
124
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
1087.4
158.5
135
24
189
Kela drug reimbursment
Imatinib
+∞
131.4
105
*
L01XE01
ATC
[U] imatinib; oral
+∞
105.8
88
*
XW000
NOMESCO Finland
Bone marrow biopsy
66.3
66.7
76
24
L01XX05
ATC
hydroxycarbamide; oral
312.8
60.1
57
*
M04AA01
ATC
allopurinol; systemic
25.6
60.1
98
113
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
+∞
51.1
46
*
316
Kela drug reimbursment
Imatinib
+∞
46.4
42
*
152
Kela drug reimbursment
Nilotinib
+∞
39.4
36
*
L01XX28
ATC
[D] imatinib; oral
+∞
33.7
31
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
79.3
32.9
36
6
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
130.8
30.0
31
*
L01XE08
ATC
[U] nilotinib; oral
+∞
28.0
26
*
150
Kela drug reimbursment
Dasatinib
+∞
28.0
26
*
L01XE06
ATC
[U] dasatinib; systemic
+∞
24.7
23
*
212
Kela drug reimbursment
Gout
39.9
23.5
29
9
L01EA03
ATC
nilotinib; oral
+∞
20.3
19
*
328
Kela drug reimbursment
Nilotinib
+∞
20.3
19
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
60.9
18.5
21
*
L01EA02
ATC
dasatinib; oral
+∞
18.1
17
*
9875/3-C42.1
ICD-O-3
Chronic myelogenous leukemia, BCR/ABL positive of bone marrow
+∞
18.1
17
*
324
Kela drug reimbursment
Dasatinib
+∞
18.1
17
*
127
Kela drug reimbursment
Transplant complication
23.3
15.7
22
11
L03AA02
ATC
filgrastim; parenteral
15.7
14.8
24
18
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
+∞
11.6
11
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
38.4
11.5
14
*
A05AA02
ATC
ursodeoxycholic acid; oral
30.7
10.9
14
5
L04AA01
ATC
[U] ciclosporin; systemic
23.7
10.9
15
7
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
+∞
10.5
10
*
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
59.0
9.8
11
*
R50.9
ICD-10 Finland
Fever, unspecified
4.4
9.7
38
109
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
39.3
9.1
11
*
L03AA04
ATC
NA
95.3
8.5
9
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
8.4
8
*
170
Kela drug reimbursment
Bosutinib
+∞
8.4
8
*
WW500
NOMESCO Finland
Blood transfusion
9.3
8.0
16
19
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
47.5
7.8
9
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
14.4
7.5
12
9
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
84.1
7.5
8
*
WW200
NOMESCO Finland
Immunization
7.1
6.9
16
25
B99
ICD-10 Finland
Other and unspecified infectious diseases
17.7
6.8
10
6
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.2
6.8
38
144
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.1
6.6
20
44
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
6.3
74
434
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
28.0
6.3
8
*
2051A
ICD-9 Finland
Myeloid leukaemia, Chronic
+∞
6.3
6
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
6.2
31
108
C03CA01
ATC
furosemide; systemic
2.6
6.1
55
278

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(21494434) Karyotype in Bone marrow
41
11
51.85
68.22
1.8
1.0
—
—
—
0
0
(40771901) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 fusion transcript/control transcript (International Scale) [# Ratio] in Blood or Tissue by Molecular genetics method
58
0
+∞
65.81
16.6
0.0
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
45
19
34.10
65.37
2.1
2.4
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
67
97
12.11
48.88
3.6
3.0
e9/l
63.2
71.3
1.09
44
74
(42870588) Differential panel, method unspecified - Blood
103
370
7.38
29.28
20.6
5.8
—
—
—
0
0
(3018418) pH of Serum or Plasma
82
332
4.45
17.62
13.3
3.9
ph
7.4
7.4
—
9
64
(3045142) Bone marrow Pathology biopsy report
21
9
27.06
15.63
1.1
1.3
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
106
557
4.49
15.02
17.0
7.1
mmol/l
1.2
1.2
0.53
95
467
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
17
20
9.51
13.54
1.2
1.4
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
31
73
5.15
12.96
1.5
1.6
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
16
20
8.88
12.13
1.1
1.4
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
48
167
3.82
12.02
4.1
2.3
%
20.9
23.9
0.88
39
144
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
18
27
7.48
11.76
1.5
1.1
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
37
111
4.15
11.35
6.9
4.5
%
2.2
0.9
0.91
16
41
(3021589) Normoblasts [#/volume] in Blood
90
508
3.08
9.66
26.7
10.4
e9/l
0.0
0.0
0.56
82
432
(3002179) Metamyelocytes/100 leukocytes in Blood
32
98
3.92
9.44
5.9
4.7
%
1.8
0.4
—
9
28
(3030905) Polymorphonuclear cells [#/volume] in Blood
13
17
8.31
9.43
5.5
3.5
e9/l
2.8
4.9
2.13
13
17
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
11
12
9.85
9.10
1.0
1.0
—
—
—
0
0
(40758558) Short blood count panel - Blood
62
296
2.93
8.86
24.0
7.5
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
13
19
7.43
8.59
5.5
3.5
%
51.3
56.9
0.57
13
19
(3048929) Epstein Barr virus Ab [Presence] in Serum
14
23
6.64
8.35
1.1
1.5
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
36
132
3.31
8.03
1.6
1.5
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
30
98
3.61
8.00
7.5
4.7
%
0.1
0.3
0.22
13
32
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
57
273
2.81
7.94
2.9
2.0
mg/l
2.4
3.1
2.12
52
236
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
12
18
7.19
7.73
1.1
1.4
—
—
—
0
0
(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection
12
18
7.19
7.73
3.4
6.3
—
5348.0
—
0
5
(3016650) Hepatitis A virus Ab [Presence] in Serum
11
15
7.86
7.66
1.1
1.0
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
33
119
3.31
7.53
1.7
1.6
—
—
—
0
0
(44790047)
11
17
6.93
6.88
1.5
1.6
—
—
—
0
0
(44790049)
11
17
6.93
6.88
1.5
1.6
—
—
—
0
0
(44806118)
11
17
6.93
6.88
1.5
1.6
—
—
—
0
0
(44790048)
11
17
6.93
6.88
1.5
1.6
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
25
80
3.58
6.83
1.4
2.7
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
52
261
2.56
6.38
15.1
5.3
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
28
101
3.20
6.34
8.1
4.6
%
0.3
0.2
0.22
15
37
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
10
16
6.64
6.04
1.0
1.1
—
—
—
0
0
(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
17
53
3.51
4.79
1.6
2.6
g/l
7.4
7.4
—
9
39
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
17
53
3.51
4.79
1.6
2.6
—
—
—
0
0
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
17
53
3.51
4.79
1.5
2.6
g/l
3.7
3.7
—
9
37
(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
16
48
3.63
4.76
1.6
2.7
g/l
3.4
3.1
—
9
38
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
13
34
4.11
4.65
1.5
1.3
—
—
—
0
0
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
16
50
3.48
4.49
1.5
2.6
g/l
8.1
10.0
—
10
43
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
11
26
4.50
4.44
1.9
1.4
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
56
336
2.10
4.25
6.9
4.6
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
12
32
4.00
4.18
3.7
3.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
68
450
1.97
3.86
2.4
1.9
pmol/l
86.1
95.6
0.74
45
236
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
67
444
1.96
3.76
5.1
3.2
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
55
345
1.97
3.59
3.8
2.3
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
57
366
1.93
3.45
5.9
2.2
u/l
186.5
235.4
0.33
57
351
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
7
10
7.29
3.40
2.0
2.9
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
7
10
7.29
3.40
1.0
1.4
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
8
14
5.98
3.39
1.9
2.6
pg
34.0
33.3
—
8
14
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
9
19
4.98
3.29
1.0
1.2
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
6
7
8.88
3.29
1.0
1.1
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
31
164
2.14
3.17
1.9
2.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
27
136
2.21
3.11
2.7
1.9
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
37
216
1.96
2.90
1.7
1.4
g/l
1.9
2.9
2.67
28
120
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
11
36
3.23
2.87
1.7
2.1
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
11
36
3.23
2.87
1.5
1.6
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
11
36
3.23
2.87
1.5
1.6
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
31
171
2.04
2.83
1.8
1.6
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
67
476
1.77
2.80
5.2
9.1
inr
1.1
1.2
0.53
18
156
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
26
135
2.13
2.78
2.8
1.9
—
—
—
0
0
(3013727) Leukocytes other/100 leukocytes in Blood
5
6
8.57
2.77
6.0
2.3
%
52.5
62.0
—
5
6
(40765096) Chromosome analysis panel by Banding
5
6
8.57
2.77
1.4
1.5
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
50
327
1.81
2.76
4.6
2.8
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
37
220
1.92
2.74
3.9
3.0
mmol/l
2.5
2.5
0.15
37
198
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
6
10
6.20
2.72
5.0
2.5
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
6
10
6.20
2.72
1.7
1.6
u/l
175.0
170.0
—
6
10
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
8
19
4.39
2.72
1.3
1.1
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
34
197
1.95
2.71
5.3
2.7
e6/l
3.1
2.5
0.13
21
106
(3012441) Differential panel - Pleural fluid
6
11
5.64
2.57
1.7
1.8
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
32
189
1.89
2.40
2.6
2.0
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
7
17
4.27
2.39
4.9
3.1
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
5
8
6.43
2.39
1.0
1.0
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
54
377
1.69
2.31
5.7
3.0
e6/l
20.0
207.9
0.56
48
289
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
5
9
5.71
2.23
1.4
1.2
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
25
139
1.97
2.23
11.4
7.8
mmol/l
-0.3
1.2
0.54
18
111
(3037756) Immunofixation for Serum or Plasma
8
24
3.47
2.21
1.0
1.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
38
244
1.76
2.18
3.6
2.3
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
13
57
2.41
2.04
18.1
9.9
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
7
21
3.45
1.99
1.1
1.5
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
7
21
3.45
1.99
1.1
1.5
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
68
519
1.59
1.98
7.6
4.1
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
6
16
3.86
1.95
1.0
1.3
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
49
348
1.62
1.91
4.9
2.8
e6/l
0.4
0.6
0.59
43
254
(3045414) Leukocytes [Presence] in Urine
10
40
2.61
1.88
2.5
1.6
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
5
12
4.27
1.84
1.0
1.2
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
7
23
3.15
1.82
2.6
1.7
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
33
214
1.70
1.81
4.0
2.5
e6/l
1.5
1.0
0.30
21
122
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
24
3.01
1.74
1.7
1.6
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
37
250
1.65
1.74
2.0
1.7
mg/l
1.5
1.3
0.23
30
199
(3017817) Protein [Mass] in Urine collected for unspecified duration
5
13
3.94
1.73
1.2
4.4
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
5
13
3.94
1.73
1.6
2.3
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
14
69
2.14
1.71
1.4
1.6
—
—
—
0
0
(3044889) 12 lead EKG panel
96
811
1.56
1.69
5.0
4.1
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
16
84
2.02
1.67
1.4
1.6
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
7
25
2.89
1.67
2.0
4.6
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
7
25
2.89
1.67
1.0
1.3
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
5
14
3.66
1.63
1.2
1.4
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
7
26
2.78
1.60
1.1
1.2
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
7
27
2.67
1.53
1.0
1.5
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
56
429
1.50
1.52
6.5
3.5
e6/l
108.8
66.5
0.36
50
308
(3002385) Erythrocyte distribution width [Ratio]
108
949
1.56
1.48
51.0
18.4
%
14.5
13.8
5.80
108
932
(3012516) Albumin [Mass/volume] in Urine
44
323
1.52
1.45
3.7
3.4
mg/l
4895.9
53.5
1.35
34
217
(3024928) Oxygen saturation in Venous blood
6
22
2.80
1.45
2.5
3.1
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
21
129
1.74
1.39
2.3
1.7
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
13
68
2.00
1.38
1.3
1.3
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
17
3.01
1.37
1.6
1.6
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
110
1200
0.64
1.36
26.0
14.0
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
13
69
1.97
1.33
10.8
5.2
mmol/l
25.1
24.6
0.11
13
69
(3021901) Oxygen saturation in Capillary blood
6
24
2.56
1.32
3.5
2.3
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
8
34
2.43
1.31
1.0
1.2
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
8
34
2.43
1.31
1.1
1.3
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
8
35
2.36
1.29
2.0
1.5
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
21
135
1.65
1.20
1.4
1.4
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
0
33
0.00
1.18
0.0
3.1
—
1.5
—
0
33
(3019060) Gas panel - Arterial blood
15
89
1.77
1.13
5.8
4.5
—
—
—
0
0
(3000991) Gas panel - Venous blood
18
113
1.68
1.12
15.7
6.6
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
5
21
2.43
1.10
1.8
2.1
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
54
433
1.40
1.10
2.3
2.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
9
47
1.98
1.04
1.3
1.2
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
5
22
2.32
1.04
2.2
1.0
—
—
—
0
0
(4035726)
16
100
1.68
1.02
1.3
1.3
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
31
0.00
0.97
0.0
3.2
—
7.8
—
0
31
(3011397) Hemoglobin [Presence] in Urine by Test strip
34
256
1.43
0.97
3.2
3.8
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
32
414
0.71
0.93
3.1
2.9
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
10
56
1.84
0.90
2.8
2.2
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
10
56
1.84
0.90
3.8
1.7
ug/l
4.1
5.6
—
10
51
(3037467) Urinalysis macro (dipstick) panel - Urine
85
757
1.30
0.79
5.3
4.4
—
—
—
0
0
(1616796) Gas panel - Central venous blood
5
23
2.21
0.77
2.2
2.2
—
—
—
0
0
(3000492) Spirometry study
14
93
1.56
0.72
2.3
1.5
—
—
—
0
0
(3013512) EKG study
29
366
0.74
0.71
2.6
3.9
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
42
345
1.31
0.70
4.3
4.2
mg/mmol
18.4
8.5
0.39
29
223
(3017044) Thyrotropin receptor Ab [Units/volume] in Serum
5
27
1.88
0.69
1.4
1.9
—
3.4
—
0
10
(3012544) pH of Venous blood
17
121
1.46
0.66
7.4
3.4
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
7
111
0.61
0.61
1.1
1.6
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
20
0.00
0.61
0.0
2.8
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
20
0.00
0.61
0.0
2.8
—
4.1
—
0
20
(3035285) Chloride [Moles/volume] in Venous blood
0
20
0.00
0.61
0.0
2.8
—
105.9
—
0
20
(3022621) pH of Urine by Test strip
11
73
1.55
0.58
2.9
2.0
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
21
161
1.36
0.56
16.3
6.6
mmol/l
105.7
104.2
0.84
21
156
(3002256) Pathology report gross observation
18
138
1.35
0.48
1.4
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
8
56
1.45
0.43
1.8
1.5
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
5
31
1.63
0.43
2.6
1.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
39
447
0.82
0.43
4.5
4.0
—
—
—
0
0
(3022313) Gas panel - Capillary blood
8
58
1.40
0.42
4.3
3.4
—
—
—
0
0
(4306422)
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
19
151
1.30
0.41
28.1
20.9
—
1.2
—
0
18
(40761535) Cells panel - Urine sediment
14
106
1.36
0.41
3.2
3.6
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
5
34
1.49
0.41
2.2
1.5
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
8
61
1.33
0.40
2.5
4.2
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
6
43
1.41
0.35
3.8
2.6
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
62
568
1.16
0.35
4.0
3.8
estimate
0.0
0.0
—
10
104
(1002224) Polysomnography panel
6
46
1.32
0.33
1.2
1.1
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
73
683
1.14
0.29
2.7
2.8
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
28
318
0.85
0.27
4.3
3.6
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
25
286
0.85
0.27
2.6
2.9
ug/l
0.7
0.7
0.04
16
181
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
10
127
0.77
0.27
4.1
3.5
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
60
560
1.12
0.24
5.1
5.3
estimate
0.0
0.0
0.00
11
108
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
7
91
0.76
0.23
1.9
1.4
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
5
39
1.29
0.23
1.0
1.3
—
—
—
0
0
(4094501)
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
106
1026
1.13
0.21
44.1
15.6
%
37.8
40.0
2.44
83
742
(3005570) Glucose [Moles/volume] in Urine
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(3038026) Centromere Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3051014) Leukocytes [#/area] in Urine sediment by Automated count
0
10
0.00
0.21
0.0
1.8
—
4.2
—
0
5
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.2
—
20.8
—
0
10
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
118
1150
1.15
0.21
36.2
14.9
mg/l
19.3
23.3
0.91
106
909
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
12
144
0.82
0.21
8.0
8.1
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
10
81
1.25
0.19
1.0
1.1
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
7
59
1.20
0.18
1.0
1.4
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
5
70
0.70
0.17
4.8
3.4
%
62.9
46.4
—
5
70
(3035350) Ketones [Presence] in Urine by Test strip
59
561
1.09
0.15
3.9
3.8
estimate
0.0
0.0
—
9
112
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
9
108
0.82
0.13
1.4
2.8
ug/l
5.2
8.7
—
9
97
(3020564) Creatinine [Moles/volume] in Serum or Plasma
119
1207
0.92
0.10
43.6
17.7
umol/l
95.0
79.9
2.36
119
1207
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
46
480
0.94
0.09
2.7
3.9
ng/l
22.6
40.4
1.38
35
351
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
11
123
0.89
0.08
1.5
1.3
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
63
1.12
0.08
1.1
1.3
—
—
—
0
0
(3022145) Colonoscopy Study observation
15
137
1.11
0.08
1.2
1.3
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
6
72
0.83
0.08
1.3
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
34
324
1.06
0.07
4.0
3.1
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
7
80
0.87
0.07
1.3
1.5
—
—
—
0
0
(4010399)
9
83
1.09
0.07
1.6
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
30
315
0.94
0.07
5.0
3.9
estimate
0.0
0.0
—
9
103
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
9
87
1.04
0.07
1.4
1.7
—
—
—
0
0
(3019225) pH of Specimen
9
101
0.88
0.06
9.1
5.1
—
—
—
0
0
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
9
103
0.87
0.06
5.2
3.1
mmol/l
1.2
1.2
—
9
86
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
16
170
0.93
0.04
1.7
1.4
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
37
380
0.96
0.03
3.6
4.2
%
24.1
20.7
0.52
16
176
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
48
489
0.97
0.02
4.6
4.8
ug/l
1.9
2.1
0.24
43
428
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
108
1084
0.98
0.00
35.4
14.2
ml/min/173m2
73.5
80.3
2.00
99
901
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
20
199
1.01
0.00
1.2
1.2
iu/ml
18.4
44.6
—
6
59
(3003694) ABO and Rh group [Type] in Blood
30
297
1.01
0.00
1.4
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
16
155
1.04
0.00
1.2
1.3
—
—
—
0
0
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004451) EKG impression Narrative
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3037556) Urate [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028433) Virus identified in Specimen by Culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.2
—
114.5
—
0
6
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
8.4
—
0.6
—
0
9
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045716) Anion gap in Serum or Plasma
0
7
0.00
0.00
0.0
1.7
—
7.9
—
0
7
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
63
0.95
0.00
3.5
2.7
%
0.9
1.3
—
6
63
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
8
86
0.93
0.00
1.3
1.8
—
—
—
0
0
(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
2.0
—
52.8
—
0
8
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020876) Protein [Mass/time] in 24 hour Urine
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(4146454)
0
9
0.00
0.00
0.0
3.2
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019420) Tryptase [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.4
—
9.1
—
0
7
(3044007) Cell count panel - Peritoneal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
6
60
1.00
0.00
3.5
2.7
%
0.5
0.8
—
6
60
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
0
5
0.00
0.00
0.0
6.2
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
7
79
0.88
0.00
3.6
3.5
g/l
106.0
132.2
—
7
79
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
28.2
—
0
5
(3028772) Osteocalcin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
(3020491) Glucose [Moles/volume] in Blood
0
5
0.00
0.00
0.0
2.4
—
6.4
—
0
5
(3005033) Fetal Nuchal fold Thickness US
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3048402) Erythrocytes [#/area] in Urine sediment by Automated count
0
5
0.00
0.00
0.0
1.4
—
0.6
—
0
5
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.6
—
9.8
—
0
9
(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum
0
5
0.00
0.00
0.0
3.0
—
12.5
—
0
5
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3011436) Histone Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
(3013005) Retinol [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.6
—
1.9
—
0
5
(3035320) C reactive protein [Mass/volume] in Body fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(3024263) Appearance of Synovial fluid
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3013637) Mi-2 Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
9
98
0.91
0.00
4.0
3.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_CML – Chronic myeloid leukaemia

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).