Acute drug-induced interstitial lung disorder

ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J70.2#

1 out of 7 registries used, show all original rules.

249

4. Check minimum number of events

None

249

5. Include endpoints

None

249

6. Filter based on genotype QC (FinnGen only)

249

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2095 1174 893
Only index persons 1591 915 676
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.02
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 71.85 72.84 70.45
Only index persons 70.45 71.25 69.35

-FinnGen-

Key figures

All Female Male
Number of individuals 249 122 127
Unadjusted period prevalence (%) 0.05 0.04 0.06
Median age at first event (years) 67.86 64.71 70.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
233
Matched controls
2329
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
+∞
323.0
233
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
25.3
48.3
69
38
H02AB06
ATC
prednisolone; systemic
6.4
35.1
183
848
UGC12
NOMESCO Finland
Flexible bronchoscopy
8.7
27.6
64
97
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.8
27.0
123
439
TGC00
NOMESCO Finland
Bronchial lavation
15.4
22.9
38
29
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
5.3
20.2
69
171
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.7
20.1
63
141
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
7.9
19.4
46
70
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
6.9
19.3
51
91
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
17.0
19.0
30
20
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
13.5
19.0
33
28
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
18.3
153
823
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
16.9
57
137
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
5.2
15.7
52
122
C03CA01
ATC
furosemide; systemic
3.0
14.4
121
611
ZXE00
NOMESCO Finland
One hour or less
3.0
14.1
126
661
H02AB02
ATC
dexamethasone; systemic
4.7
13.7
50
129
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
6.8
12.7
32
53
R50.9
ICD-10 Finland
Fever, unspecified
3.9
12.4
56
176
JN4BD
NOMESCO Finland
Extensive body CT
3.9
12.2
55
172
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
31.9
11.8
15
5
A04AA02
ATC
granisetron; systemic, transdermal
5.2
11.8
37
81
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
6.6
11.3
29
49
A03FA01
ATC
metoclopramide; systemic, rectal
3.0
11.3
75
314
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.9
11.1
31
59
JN4AD
NOMESCO Finland
Body CT examination
4.3
10.9
42
114
L03AA13
ATC
pegfilgrastim; parenteral
7.0
10.7
26
41
C01BD01
ATC
amiodarone; systemic
8.4
10.7
23
30
D70.82
ICD-10 Finland
Drug-induced neutropenia
17.1
10.5
16
10
TPH04
NOMESCO Finland
Cathetrisation of vein
3.0
10.5
70
290
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
4.3
10.4
39
103
GD1AD
NOMESCO Finland
Thorax CT examination
7.3
10.2
24
36
XW000
NOMESCO Finland
Bone marrow biopsy
6.1
10.0
27
49
J01MA12
ATC
levofloxacin; systemic
2.9
9.9
71
309
R06.0
ICD-10 Finland
Dyspnoea
2.7
9.9
82
389
M04AA01
ATC
allopurinol; systemic
3.1
9.8
59
229
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.1
9.7
26
47
L04AD01
ATC
ciclosporin; systemic
22.8
9.5
13
6
ZX120
NOMESCO Finland
Intravenous
4.1
9.4
37
102
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
9.4
104
576
I50.9
ICD-10 Finland
Heart failure, unspecified
3.0
9.3
61
248
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
10.7
9.2
17
17
A02BC02
ATC
pantoprazole; systemic
2.5
9.1
170
1218
L04AA06
ATC
mycophenolic acid; systemic
25.2
9.0
12
5
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
25.2
9.0
12
5
N03AX16
ATC
pregabalin; oral
2.7
8.8
70
322
A07EC01
ATC
sulfasalazine; oral, rectal
3.9
8.8
36
103
L04AA13
ATC
leflunomide; oral
8.8
8.8
18
22
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
8.4
8.5
18
23
TPH07
NOMESCO Finland
Cathetrisation of artery
3.3
8.3
43
149
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.8
8.3
27
62
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
13.7
8.0
13
10
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
7.8
103
606
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.8
7.7
33
98
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
9.3
7.7
15
17
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
9.3
7.7
15
17
NHQ40
NOMESCO Finland
Amputation of toe
8.1
7.5
16
21
C07AB07
ATC
bisoprolol; oral
2.2
7.5
142
978
A02BC01
ATC
omeprazole; systemic
2.3
7.4
85
466
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
11.4
7.4
13
12
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
7.4
43
162
N02AA05
ATC
oxycodone; systemic
2.8
7.4
51
212
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.2
7.4
27
70
J70.3
ICD-10 Finland
Chronic drug-induced interstitial lung disorders
+∞
7.3
7
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
16.4
7.3
11
7
I50.0
ICD-10 Finland
Congestive heart failure
3.4
7.3
35
115
ZXD05
NOMESCO Finland
Urgent procedure
2.2
7.2
87
488
J01MA14
ATC
moxifloxacin; systemic
3.7
7.2
31
93
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
7.0
43
166
L04AA01
ATC
[U] ciclosporin; systemic
14.3
7.0
11
8
J96.0
ICD-10 Finland
Acute respiratory failure
14.3
7.0
11
8
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
8.7
6.9
14
17
P01BA02
ATC
hydroxychloroquine; oral
3.6
6.9
30
91
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
11.4
6.9
12
11
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.2
6.8
86
488
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
6.8
54
246
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
8.2
6.7
14
18
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.2
6.6
24
62
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.0
6.6
17
30
Z3231
NOMESCO Finland
Registered nurse
2.2
6.5
76
416
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.9
6.4
25
69
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
6.4
47
204
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
6.4
32
109
WW500
NOMESCO Finland
Blood transfusion
4.8
6.3
20
45
A04AA55
ATC
palonosetron, combinations; systemic
7.4
6.3
14
20
L04AX01
ATC
azathioprine; systemic
5.6
6.3
17
32
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
6.3
26
76
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
27.5
6.3
8
*
XX3DW
NOMESCO Finland
Time consuming IT work
2.9
6.2
39
153
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.7
6.2
20
46
WZC30
NOMESCO Finland
Teaching
2.7
6.1
42
175
B01AB10
ATC
tinzaparin; parenteral
3.4
6.1
28
89
H25.1
ICD-10 Finland
Senile nuclear cataract
2.1
6.0
87
518
L03AA14
ATC
lipegfilgrastim; parenteral
7.6
6.0
13
18

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
41
18
27.07
57.50
1.8
1.4
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
38
24
18.50
45.28
1.8
1.3
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
51
55
11.40
44.31
1.7
1.5
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
51
57
10.99
43.16
1.7
1.5
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
45
42
12.86
43.00
1.7
1.5
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
43
40
12.79
41.12
1.7
1.5
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
40
35
13.42
39.70
1.7
1.5
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
40
36
13.05
38.99
1.8
1.4
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
26
14
20.62
33.05
1.8
1.3
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
26
14
20.62
33.05
1.8
1.3
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
29
20
16.28
32.75
1.9
1.3
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
33
30
12.53
31.77
1.8
1.6
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
35
36
11.15
31.05
1.8
1.6
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
27
18
16.70
30.98
1.8
1.3
—
—
—
0
0
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
38
53
8.28
26.65
1.6
1.2
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
81
248
4.36
24.35
2.6
1.8
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
79
245
4.26
23.23
2.5
1.7
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
31
41
8.49
22.61
4.2
2.7
%
61.7
59.9
0.24
31
41
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
26
28
10.25
22.14
1.1
1.2
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
136
625
3.59
22.12
7.5
4.1
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
30
40
8.39
21.71
3.5
2.2
e9/l
4.4
4.8
0.35
30
40
(3042631) Mycobacterium sp identified in Specimen
26
29
9.89
21.58
2.4
3.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
95
356
3.70
21.05
2.7
1.8
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
138
658
3.46
20.82
10.2
5.0
—
—
—
0
0
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
17
12
15.13
18.66
1.7
2.1
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
61
182
4.11
18.56
4.5
4.1
%
1.0
1.0
0.01
34
62
(3022096) Basophils/100 leukocytes in Blood
160
877
3.31
18.40
11.6
5.4
%
0.6
0.6
0.26
155
813
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
70
234
3.77
18.09
5.3
3.7
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
22
25
9.56
17.93
2.9
1.6
%
88.7
89.9
0.35
22
25
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
32
58
6.18
17.46
1.7
1.5
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
55
159
4.16
17.40
4.4
4.1
%
1.0
0.4
1.39
30
40
(3021440) Promyelocytes/100 leukocytes in Blood
57
171
4.03
17.12
4.4
4.3
%
0.2
0.1
0.35
33
55
(3012501) Base excess in Blood by calculation
28
46
6.73
16.78
5.5
2.5
mmol/l
2.9
2.4
0.32
20
26
(40767503) Oxygen content in Capillary blood by calculation
28
46
6.73
16.78
3.6
2.6
%
16.8
15.4
0.60
11
26
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
37
80
5.26
16.73
2.6
2.8
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
55
164
4.02
16.64
4.3
4.3
%
0.1
0.2
0.25
30
48
(3001604) Monocytes [#/volume] in Blood
167
978
3.15
16.39
10.8
5.2
e9/l
0.6
0.6
0.91
159
845
(3006315) Basophils [#/volume] in Blood
167
984
3.12
16.09
10.9
5.2
e9/l
0.0
0.0
0.62
159
854
(3013115) Eosinophils [#/volume] in Blood
170
1013
3.14
16.03
11.1
5.4
e9/l
0.2
0.2
0.60
163
890
(3017143) Hepatitis C virus Ab [Presence] in Serum
56
174
3.86
15.94
1.8
1.4
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
168
1004
3.07
15.58
11.4
5.3
e9/l
1.6
1.9
1.63
163
893
(1616796) Gas panel - Central venous blood
26
43
6.63
15.46
4.2
3.0
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
51
152
3.96
15.37
4.1
2.9
g/l
10.1
10.3
0.10
46
138
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
58
191
3.66
15.12
1.7
1.4
—
—
—
0
0
(3018418) pH of Serum or Plasma
127
664
2.86
14.93
9.3
3.9
ph
7.4
7.4
1.43
55
132
(40761536) Microorganisms panel - Urine sediment
54
176
3.64
14.24
4.7
4.1
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
60
210
3.45
14.19
1.7
1.7
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
41
112
4.19
13.85
1.2
1.3
—
—
—
0
0
(44806118)
19
25
8.15
13.75
1.4
1.5
—
—
—
0
0
(44790047)
19
25
8.15
13.75
1.4
1.5
—
—
—
0
0
(44790049)
19
25
8.15
13.75
1.4
1.5
—
—
—
0
0
(44790048)
19
25
8.15
13.75
1.4
1.5
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
22
35
6.80
13.52
1.5
2.9
—
—
—
0
0
(3020229) Cytomegalovirus DNA [Presence] in Specimen by NAA with probe detection
17
6
30.24
13.14
1.2
1.0
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
56
197
3.38
13.06
2.5
1.9
nmol/l
363.2
379.0
0.15
56
180
(3042936) Bacteria identified in Isolate by Culture
75
315
2.98
12.95
2.4
1.8
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
14
14
10.54
12.34
2.4
1.1
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
176
1161
2.76
12.14
18.0
8.5
e9/l
4.5
4.2
0.98
170
1016
(40760892) CBC W Ordered Manual Differential panel - Blood
88
422
2.68
11.67
8.8
5.3
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
58
226
3.04
11.31
1.5
1.3
titre
125.7
546.4
2.59
14
56
(3026782) Osmolality of Urine
89
450
2.52
10.40
3.9
3.1
mosm/kgh2o
519.6
564.8
1.25
81
382
(3021589) Normoblasts [#/volume] in Blood
141
880
2.39
10.25
24.7
10.4
e9/l
0.0
0.0
0.01
127
731
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
20
39
5.49
10.01
2.1
1.7
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
102
567
2.35
9.51
4.8
3.3
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
148
966
2.31
9.40
11.2
5.3
mmol/l
1.2
1.2
0.65
142
867
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
158
1068
2.31
9.12
11.3
6.0
mmol/l
1.2
1.2
0.60
107
893
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
26
70
4.03
8.87
1.9
1.8
—
136.0
—
0
5
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
15
25
6.32
8.76
1.3
1.2
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
88
476
2.31
8.58
4.0
2.7
e6/l
7.0
4.5
0.59
81
417
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
21
49
4.59
8.58
1.3
1.1
—
—
—
0
0
(3019060) Gas panel - Arterial blood
41
153
3.01
8.50
4.7
3.6
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
138
901
2.19
8.43
19.1
9.8
inr
1.2
1.3
0.90
66
258
(3004588) Protein electrophoresis panel - Serum or Plasma
43
167
2.90
8.30
4.3
2.3
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
64
306
2.47
8.20
3.4
2.5
%
21.6
21.1
0.11
54
263
(4035726)
45
183
2.78
7.97
1.6
1.4
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
57
263
2.51
7.85
7.7
5.7
mmol/l
1.3
1.0
0.24
44
209
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
15
28
5.64
7.83
1.3
1.3
—
—
—
0
0
(3037692) Legionella sp identified in Specimen by Organism specific culture
12
8
15.67
7.79
1.3
1.3
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
78
418
2.26
7.65
3.7
1.7
mg/l
1.5
1.3
0.19
64
320
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
11
15
7.63
7.61
1.2
1.0
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
101
604
2.13
7.51
5.0
3.4
e6/l
0.3
0.5
0.77
90
462
(40760888) Immunoglobulin light chains.free panel - Serum
20
51
4.18
7.31
3.8
4.7
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
10
13
7.97
7.17
2.0
1.7
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
13
24
5.66
6.84
1.3
1.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
119
779
2.01
6.75
4.7
3.4
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
105
664
2.01
6.51
5.0
3.5
e6/l
25.5
165.6
0.83
91
522
(3026493) Urate [Moles/volume] in Serum or Plasma
86
511
2.04
6.30
3.5
2.9
umol/l
5685.2
7904.1
0.15
74
422
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
67
3.50
6.30
4.0
2.4
u/ml
0.3
0.4
0.29
16
37
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
13
26
5.22
6.29
1.2
1.7
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
100
639
1.94
5.89
3.0
2.3
u/l
55.3
56.4
0.10
94
588
(3016650) Hepatitis A virus Ab [Presence] in Serum
14
32
4.58
5.84
1.1
1.1
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
37
159
2.56
5.84
2.4
1.5
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
13
28
4.84
5.80
1.2
1.6
—
—
—
0
0
(3006184) Hemoglobin [Mass/volume] in Capillary blood
18
52
3.65
5.56
2.8
2.4
g/l
132.3
123.9
0.51
12
37
(3015377) Calcium [Moles/volume] in Serum or Plasma
106
706
1.87
5.40
3.9
3.1
mmol/l
2.3
2.4
0.17
96
611
(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma
22
76
3.08
5.18
5.5
3.8
mg/l
60.2
32.0
0.64
12
59
(3034860) Kappa light chains.free [Mass/volume] in Serum
22
76
3.08
5.18
5.5
3.8
mg/l
140.5
158.5
0.06
12
59
(3025941) Bacteria identified in Stool by Culture
27
105
2.76
5.17
1.5
1.3
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
16
45
3.73
5.13
1.8
1.4
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
16
45
3.73
5.13
1.8
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
81
503
1.90
5.06
15.6
6.5
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
11
23
4.96
5.06
2.0
1.1
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
14
36
4.06
5.06
1.1
1.5
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
11
24
4.75
4.83
1.1
1.0
—
—
—
0
0
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
8
7
11.75
4.82
3.4
8.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
101
682
1.81
4.79
4.9
3.3
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
107
736
1.80
4.77
4.6
3.3
ng/l
1499.9
1733.1
0.35
99
635
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
30
129
2.51
4.72
1.2
1.4
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
16
48
3.49
4.69
1.1
1.3
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
109
757
1.78
4.68
5.6
4.1
e6/l
98.2
93.0
0.04
96
559
(3048929) Epstein Barr virus Ab [Presence] in Serum
14
39
3.74
4.55
1.4
1.2
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
14
39
3.74
4.55
2.1
1.6
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
41
206
2.19
4.55
3.3
2.4
e9/l
71.2
67.8
0.24
34
161
(3002032) Base excess in Venous blood by calculation
41
206
2.19
4.55
5.0
4.1
mmol/l
2.3
2.0
0.20
31
157
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
16
50
3.35
4.42
1.1
1.1
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
11
26
4.38
4.40
1.1
1.0
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
15
45
3.48
4.40
1.3
1.3
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
156
1225
1.73
4.17
9.4
4.3
mmol/l
6.8
6.8
0.00
146
1153
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
25
106
2.51
4.06
12.1
7.0
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
16
53
3.16
4.04
2.6
1.5
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
11
29
3.92
3.84
1.5
1.4
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
13
39
3.46
3.81
1.1
1.1
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
43
236
1.99
3.78
9.6
6.0
%
94.0
95.1
0.63
43
231
(3012544) pH of Venous blood
40
214
2.04
3.77
4.8
4.0
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
16
56
2.98
3.70
1.6
1.4
iu/ml
0.0
0.0
—
5
14
(3007853) Bacteria identified in Skin by Aerobe culture
43
238
1.98
3.69
2.2
1.7
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
108
790
1.65
3.60
3.5
2.7
ug/l
205.1
136.0
1.20
101
715
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
186
1567
1.74
3.53
18.0
7.3
u/l
79.3
80.6
0.15
186
1466
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
11
31
3.67
3.52
1.7
1.5
pg
31.3
33.0
0.55
11
31
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
27
127
2.26
3.51
4.0
3.4
mmol/l
2.8
1.9
0.78
19
92
(3021901) Oxygen saturation in Capillary blood
14
47
3.10
3.47
2.9
2.5
—
—
—
0
0
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
7
10
7.16
3.38
1.0
1.1
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
80
550
1.67
3.35
5.6
3.8
—
—
—
0
0
(3000492) Spirometry study
29
144
2.15
3.32
1.9
1.5
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
121
926
1.60
3.27
3.0
2.5
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
28
139
2.14
3.21
4.0
3.2
kpa
5.0
5.1
0.34
28
127
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
23
105
2.31
3.20
2.4
2.6
pmol/l
4.3
4.3
0.01
18
90
(3029937) Albumin [Presence] in Urine by Test strip
82
573
1.64
3.20
5.7
4.4
estimate
0.0
0.0
0.00
48
200
(3000494) Fungus identified in Specimen by Culture
42
242
1.88
3.20
1.8
1.4
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
16
61
2.73
3.20
1.3
1.8
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
115
875
1.58
3.15
6.2
4.3
ng/l
38.7
40.3
0.06
95
683
(3007164) IgA [Mass/volume] in Serum or Plasma
57
363
1.74
3.14
2.5
1.4
g/l
3.2
2.7
0.59
42
206
(3028626) Oxygen [Partial pressure] in Capillary blood
15
57
2.74
3.02
2.8
2.4
kpa
8.2
7.8
0.45
15
51
(3009343) pH of Capillary blood
27
136
2.11
2.99
4.1
3.3
ph
7.4
7.4
—
9
20
(3013707) Erythrocyte sedimentation rate by Westergren method
172
1449
1.60
2.96
7.9
4.2
mm/h
20.2
13.7
4.49
162
1316
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
47
288
1.78
2.95
1.3
1.3
u/ml
83.5
15.1
1.21
13
110
(3037467) Urinalysis macro (dipstick) panel - Urine
163
1357
1.58
2.94
6.8
4.6
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
8
17
4.82
2.94
1.3
1.2
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
10
30
3.43
2.94
1.5
1.5
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
16
65
2.56
2.85
1.4
1.2
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
16
66
2.52
2.77
2.9
2.5
mmol/l
23.9
24.6
0.37
16
55
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
8
19
4.31
2.70
1.1
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
16
67
2.48
2.69
1.4
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
16
68
2.45
2.61
1.4
1.2
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
7
15
4.77
2.61
1.1
1.1
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
25
3.69
2.60
1.0
1.1
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
125
1004
1.49
2.50
5.5
4.2
estimate
0.0
0.0
0.00
52
197
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
101
779
1.50
2.45
5.7
4.4
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
6
12
5.09
2.41
1.0
1.0
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
8
22
3.72
2.38
1.5
1.5
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
5
8
6.35
2.38
1.2
1.3
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
123
993
1.47
2.35
6.8
5.6
estimate
0.0
0.0
0.00
50
209
(3035350) Ketones [Presence] in Urine by Test strip
122
984
1.47
2.34
5.5
4.1
estimate
0.0
0.0
0.00
54
211
(3005322) IgE [Units/volume] in Serum or Plasma
19
93
2.13
2.28
1.5
1.2
u/ml
1142.8
230.3
0.61
19
83
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
13
54
2.48
2.23
1.3
1.2
—
—
—
0
0
(3024354) Oxygen [Partial pressure] in Venous blood
30
176
1.80
2.18
3.3
3.1
kpa
4.7
4.2
0.77
30
168
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
6
14
4.36
2.16
1.2
1.0
—
—
—
0
0
(3020891) Body temperature
19
96
2.06
2.12
3.8
4.0
—
—
—
0
0
(3035320) C reactive protein [Mass/volume] in Body fluid
5
10
5.08
2.08
1.4
1.9
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
5
10
5.08
2.08
2.4
2.2
—
—
—
0
0
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
6
15
4.07
2.05
1.5
1.0
—
—
—
0
0
(3044889) 12 lead EKG panel
160
1381
1.44
2.03
6.5
4.4
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
30
180
1.76
2.03
2.1
2.3
u/l
36.6
33.6
0.13
25
147
(3003694) ABO and Rh group [Type] in Blood
63
458
1.50
1.98
1.5
1.3
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
54
380
1.54
1.98
6.4
3.7
ng/l
1012.4
140.5
0.57
49
320
(3000991) Gas panel - Venous blood
31
190
1.72
1.96
11.9
7.1
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
8
27
3.03
1.95
1.6
1.3
—
—
—
0
0
(40768441) Liver Pathology biopsy report
6
16
3.81
1.94
1.8
1.1
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
10
39
2.63
1.94
1.4
1.5
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
11
46
2.46
1.88
5.5
2.5
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
11
46
2.46
1.88
1.5
2.8
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
8
28
2.92
1.88
2.8
4.4
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
6
17
3.59
1.85
1.2
1.1
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
6
17
3.59
1.85
1.2
1.2
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
6
17
3.59
1.85
4.5
4.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
5
12
4.23
1.83
1.0
1.0
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
5
12
4.23
1.83
1.0
1.0
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
7
23
3.10
1.81
1.6
3.3
u/ml
19.8
84.9
—
7
23
(40759836) Histone Ab [Presence] in Serum by Immunoblot
5
13
3.90
1.72
1.4
1.2
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
5
13
3.90
1.72
1.4
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
5
13
3.90
1.72
1.4
1.2
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
12
55
2.24
1.70
3.8
2.3
%
89.8
87.2
0.16
12
50
(3004716) Salmonella sp identified in Stool by Organism specific culture
17
90
1.95
1.70
1.4
1.3
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
7
25
2.85
1.66
1.3
1.7
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
7
25
2.85
1.66
1.3
1.7
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
7
25
2.85
1.66
1.3
1.7
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
5
14
3.62
1.62
1.4
1.2
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
5
14
3.62
1.62
1.4
1.2
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
5
14
3.62
1.62
1.4
1.2
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
62
467
1.44
1.62
2.2
1.8
pmol/l
492.5
443.1
0.87
50
379
(3045788) Cell count panel - Pleural fluid
6
20
3.05
1.59
2.2
1.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
44
312
1.50
1.56
1.4
1.3
iu/ml
62.4
44.8
0.30
17
102
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
71
553
1.40
1.54
2.9
2.1
mg/l
3.6
3.2
0.50
65
470
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
46
620
0.68
1.53
4.3
4.7
%
22.9
21.2
0.22
24
319
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
175
1909
0.72
1.53
4.9
5.4
mmol/l
2.6
2.6
0.02
155
1731
(3000570) Elastase.pancreatic [Mass/mass] in Stool
11
51
2.21
1.53
1.1
1.4
ug/g
261.2
305.3
—
5
29
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
170
1862
0.73
1.51
4.4
4.8
mmol/l
4.5
4.5
0.10
154
1704
(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis
15
80
1.93
1.48
9.7
2.0
g/l
37.0
37.3
0.06
15
70
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
6
22
2.77
1.44
1.2
1.2
—
—
—
0
0
(40768793) Breast Pathology biopsy report
10
46
2.22
1.42
1.4
1.3
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
33
225
1.54
1.40
1.4
1.4
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
56
427
1.40
1.36
4.0
3.0
mmol/l
2.5
2.5
0.99
49
376
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
160
1433
1.33
1.32
4.7
3.9
pmol/l
15.0
15.0
0.09
138
1257
(3017817) Protein [Mass] in Urine collected for unspecified duration
5
18
2.81
1.29
1.4
3.3
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
170
1847
0.75
1.28
4.3
4.8
mmol/l
1.4
1.5
0.82
153
1672
(3008757) Leukocyte morphology finding [Identifier] in Blood
6
25
2.43
1.25
2.3
4.0
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
107
912
1.30
1.25
5.9
4.1
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
164
1787
0.76
1.23
3.9
4.2
mmol/l
1.3
1.3
0.51
144
1608
(3044927) Protein electrophoresis panel - Urine
5
19
2.66
1.22
1.4
1.1
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
20
125
1.65
1.22
2.8
1.8
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
131
1150
1.29
1.21
4.1
3.0
u/l
90.9
51.4
1.71
124
1042
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
174
1879
0.75
1.20
5.1
5.0
mmol/l
6.2
6.1
0.39
150
1696
(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
87
1.77
1.18
9.7
2.0
g/l
3.2
3.2
0.00
15
73
(4010399)
24
159
1.56
1.17
1.5
1.4
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
97
822
1.29
1.17
2.9
2.3
nmol/l
80.1
78.7
0.20
88
715
(3019309) Folate [Moles/volume] in Red Blood Cells
57
450
1.35
1.13
1.9
1.8
nmol/l
1146.7
1170.5
0.08
43
346
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
89
1.73
1.10
9.7
1.9
g/l
10.1
10.6
0.20
15
79
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
13
74
1.80
1.09
3.1
1.9
ug/l
101.8
369.4
2.03
13
68
(3009542) Hematocrit [Volume Fraction] of Blood
176
1621
1.29
1.05
32.4
17.2
%
37.6
39.4
1.32
100
1044
(21494890) Protein electrophoresis panel - 24 hour Urine
5
23
2.20
0.98
2.6
2.9
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
29
0.00
0.98
0.0
1.6
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
29
0.00
0.98
0.0
1.6
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
29
0.00
0.98
0.0
1.6
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
168
1806
0.79
0.98
6.8
6.5
mmol/mol
41.8
40.9
0.57
151
1663
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
30
0.00
0.98
0.0
1.5
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
30
0.00
0.98
0.0
1.5
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
7
36
1.97
0.98
1.7
2.7
%
57.4
60.4
—
7
36
(40768797) Stomach Pathology biopsy report
37
279
1.38
0.98
1.2
1.2
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
32
0.00
0.95
0.0
1.4
—
—
—
0
0
(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
94
1.63
0.93
9.7
1.9
g/l
6.9
7.5
0.98
15
73
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
94
1.63
0.93
9.7
1.9
—
—
—
0
0
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
94
1.63
0.93
9.7
1.9
g/l
3.7
3.8
0.09
15
72
(3013512) EKG study
78
660
1.26
0.92
4.4
4.3
—
—
—
0
0
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
6
28
2.17
0.92
1.3
1.1
—
—
—
0
0
(3019225) pH of Specimen
13
202
0.62
0.87
3.6
3.8
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
19
271
0.68
0.86
17.3
8.4
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
45
358
1.31
0.85
4.3
3.0
e6/l
0.5
1.2
1.71
33
209
(36660697) Celiac disease serology panel - Serum
18
121
1.53
0.85
1.2
1.2
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
8
45
1.80
0.85
2.0
1.5
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
30
224
1.39
0.85
4.6
2.5
umol/l
6.8
8.7
0.54
23
196
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
11
65
1.72
0.84
1.6
1.3
g/l
0.2
0.2
0.03
11
65
(4094501)
8
48
1.69
0.79
1.1
1.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
201
1907
1.28
0.79
38.8
16.2
mg/l
24.5
25.4
0.17
192
1539
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
27
0.00
0.78
0.0
1.6
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
9
53
1.72
0.76
1.0
1.1
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
42
337
1.30
0.76
4.6
3.3
e6/l
1.3
2.2
0.81
30
190
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
36
450
0.77
0.74
3.3
3.2
ug/l
1.0
0.8
0.43
24
313
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
9
55
1.66
0.74
1.7
1.8
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
106
0.56
0.74
1.8
1.8
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
5
25
2.02
0.73
1.0
1.2
—
—
—
0
0
(4281824)
5
25
2.02
0.73
1.0
1.1
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
11
69
1.62
0.69
6.9
3.0
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
5
27
1.87
0.69
1.2
1.1
—
—
—
0
0
(3002256) Pathology report gross observation
31
242
1.32
0.68
1.6
1.3
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
68
782
0.82
0.68
5.4
5.4
ug/l
2.5
2.9
0.26
55
687
(21494755) Public health laboratory ask at order entry panel
5
91
0.54
0.68
1.2
1.5
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
88
785
1.19
0.61
2.3
2.3
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
23
0.00
0.58
0.0
2.6
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
73
643
1.19
0.58
3.2
2.4
—
—
—
0
0
(1002224) Polysomnography panel
8
54
1.50
0.58
1.1
1.1
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
6
37
1.64
0.56
1.2
1.2
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
6
40
1.51
0.52
4.7
2.4
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
30
244
1.26
0.51
2.6
4.2
ug/l
12.1
59.0
0.81
22
209
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
9
65
1.40
0.51
1.6
1.2
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
37
436
0.82
0.48
6.6
4.6
kg/l
1.0
1.0
—
5
62
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
91
0.65
0.43
1.3
2.1
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
66
592
1.16
0.42
3.7
3.3
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
(40768443) Skin Pathology biopsy report
13
97
1.36
0.40
1.2
1.3
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
21
169
1.26
0.40
1.7
1.5
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
15
115
1.32
0.40
2.7
2.8
%
1.0
1.0
0.27
15
115
(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay
0
19
0.00
0.39
0.0
1.0
—
38.6
—
0
10
(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid
0
19
0.00
0.39
0.0
1.0
—
283.7
—
0
10
(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid
0
19
0.00
0.39
0.0
1.0
—
466.0
—
0
11
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
175
1816
0.88
0.39
35.7
15.6
ml/min/173m2
72.4
74.4
0.58
164
1483
(3049717) Cytology report of Urine Cyto stain
14
107
1.33
0.38
1.8
3.0
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
45
396
1.17
0.37
1.2
1.2
u/ml
0.6
1.4
—
8
108
(3036489) Thrombin time
9
70
1.30
0.37
4.2
2.2
s
24.2
21.9
—
9
63
(3019550) Sodium [Moles/volume] in Serum or Plasma
196
2017
0.87
0.37
38.6
18.9
mmol/l
138.9
139.7
2.82
189
1955
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
19
157
1.23
0.30
2.0
1.7
%
1.6
1.6
0.05
12
129
(3023103) Potassium [Moles/volume] in Serum or Plasma
197
2019
0.88
0.30
39.7
19.0
mmol/l
4.0
4.0
0.41
190
1958
(3045414) Leukocytes [Presence] in Urine
10
76
1.33
0.28
3.3
2.0
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
48
526
0.89
0.26
1.6
1.6
mmol/l
1.5
1.3
1.05
35
431
(3020564) Creatinine [Moles/volume] in Serum or Plasma
198
2023
0.90
0.25
42.3
19.3
umol/l
91.0
81.8
1.42
198
2023
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
6
83
0.72
0.24
1.3
2.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
5
38
1.32
0.23
2.6
1.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
180
1754
1.09
0.23
5.6
4.7
mu/l
2.1
2.0
0.13
158
1550
(3016921) Smith extractable nuclear Ab [Units/volume] in Serum
5
40
1.26
0.22
1.2
1.3
—
1.8
—
0
6
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3017315) Amylase [Enzymatic activity/volume] in Urine
0
10
0.00
0.21
0.0
1.0
—
305.3
—
0
10
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
10
0.00
0.21
0.0
16.4
—
—
—
0
0
(3006653) Thiamine [Moles/volume] in Blood
0
12
0.00
0.21
0.0
1.1
—
133.2
—
0
12
(3001019) Free T4 and TSH panel - Serum or Plasma
5
43
1.17
0.21
2.0
1.3
—
—
—
0
0
(3032773) Endomysium IgG Ab [Titer] in Serum
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
73
690
1.08
0.19
4.1
4.0
mg/mmol
9.1
10.9
0.26
45
438
(3000330) Specific gravity of Urine by Test strip
13
110
1.19
0.17
5.3
4.7
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
8
71
1.13
0.16
5.1
5.4
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
9
79
1.14
0.15
1.0
1.0
—
—
—
0
0
(40761535) Cells panel - Urine sediment
21
189
1.12
0.14
5.1
3.6
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
20
220
0.90
0.12
1.5
1.4
—
—
—
0
0
(3022145) Colonoscopy Study observation
22
240
0.91
0.12
1.6
1.2
—
—
—
0
0
(3022313) Gas panel - Capillary blood
11
96
1.15
0.10
5.4
3.2
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
10
87
1.16
0.09
2.3
1.9
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
90
877
1.04
0.08
2.1
2.0
pmol/l
90.1
93.4
0.37
47
442
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
64
1.10
0.08
1.3
1.0
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
10
112
0.89
0.07
1.2
1.2
—
27.8
—
0
7
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
81
0.86
0.07
1.9
1.8
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
9
103
0.87
0.06
1.7
1.2
—
—
—
0
0
(3022621) pH of Urine by Test strip
14
130
1.08
0.04
6.0
2.9
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
67
657
1.03
0.04
2.9
3.2
mg/l
51.1
158.5
0.58
47
430
(3011397) Hemoglobin [Presence] in Urine by Test strip
45
461
0.97
0.03
4.8
4.0
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
67
661
1.02
0.02
2.9
3.1
mmol/l
5.8
7.3
3.30
51
542
(40761511) CBC panel - Blood by Automated count
198
1972
1.02
0.01
33.6
15.2
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
17
172
0.99
0.00
11.9
2.9
ml/min/173m2
57.6
58.6
—
9
69
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
121
0.99
0.00
2.8
2.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
49
488
1.01
0.00
3.1
2.2
—
—
—
0
0
(3020951) Lymphocytes/100 leukocytes in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027300) Silver Birch IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
1363.4
—
0
5
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
10.0
—
588.0
—
0
5
(3019779) Phenytoin [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
4.6
—
45.4
—
0
5
(3034426) Prothrombin time (PT)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3022689) Creatine [Moles/volume] in Urine
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum
0
7
0.00
0.00
0.0
1.0
—
10.5
—
0
7
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
30.6
—
0
7
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(44813793)
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011544) Albumin [Mass/volume] in Pleural fluid
0
6
0.00
0.00
0.0
1.0
—
19.8
—
0
6
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
15.4
—
992.8
—
0
5
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
6
0.00
0.00
0.0
1.0
—
9.6
—
0
6
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
5.8
—
227.4
—
0
8
(3034988) Calcium [Moles/volume] in Capillary blood
0
5
0.00
0.00
0.0
2.4
—
1.2
—
0
5
(3019832) Treponema pallidum Ab [Presence] in Serum
7
72
0.97
0.00
1.4
1.8
—
—
—
0
0
(3000285) Sodium [Moles/volume] in Blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
8
85
0.94
0.00
1.3
1.3
—
—
—
0
0
(3018851) Theophylline [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
41.7
—
0
6
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.3
—
86.5
—
0
6

Mortality – FinRegistry

Association

Association between endpoint ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD and mortality.

Females

Parameter HR [95% CI] p-value
ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD 2.16 [1.79, 2.61] < 0.001
Birth year 0.993 [0.98, 1.0] 0.097

During the follow-up period (1.1.1998 — 31.12.2019), 543 out of 1003 females with ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD died.

Males

Parameter HR [95% CI] p-value
ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD 3.019 [2.39, 3.81] < 0.001
Birth year 0.992 [0.98, 1.0] 0.103

During the follow-up period (1.1.1998 — 31.12.2019), 468 out of 739 males with ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD died.

Mortality risk

Mortality risk for people of age

years, who have ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD.

N-year risk Females Males
1 0.208% 0.651%
5 1.326% 4.207%
10 3.024% 10.044%
15 5.758% 18.972%
20 10.277% 30.484%

Relationships between endpoints

Index endpoint: ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD – Acute drug-induced interstitial lung disorder

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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