Allergic bronchopulmonary aspergillosis (ABPA)

ABPA

aspergillosis: Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma , a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess , is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B44.1
  • Cause of death: ICD-10 B44.1

2 out of 7 registries used, show all original rules.

130

4. Check minimum number of events

None

130

5. Include endpoints

None

130

6. Filter based on genotype QC (FinnGen only)

130

Control definitions (FinnGen only)

Control exclude
ASTHMA_COMORB

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
B44
Name in latin
Aspergillosis pulmonalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 699 250 439
Only index persons 549 205 344
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 65.91 66.25 65.77
Only index persons 65.36 65.64 65.20

-FinnGen-

Key figures

All Female Male
Number of individuals 130 48 82
Unadjusted period prevalence (%) 0.03 0.02 0.04
Median age at first event (years) 63.64 58.06 66.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
115
Matched controls
1149
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
+∞
150.4
109
*
J02AC03
ATC
voriconazole; systemic
+∞
57.1
50
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
32.2
55.7
88
105
UGC12
NOMESCO Finland
Flexible bronchoscopy
39.4
48.6
63
34
H02AB06
ATC
prednisolone; systemic
25.6
42.7
103
288
GD1AA
NOMESCO Finland
Thorax X-ray examination
19.2
41.3
95
227
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
23.5
38.6
59
49
TGC00
NOMESCO Finland
Bronchial lavation
100.5
37.9
40
6
J01MA14
ATC
moxifloxacin; systemic
23.9
37.8
57
45
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
39.3
36.5
46
19
R03BB04
ATC
tiotropium bromide; inhalant
23.4
36.4
55
43
J01MA12
ATC
levofloxacin; systemic
16.0
35.2
66
89
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
31.0
34.1
46
24
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
31.2
33.5
45
23
J45.9
ICD-10 Finland
Asthma, unspecified
16.6
32.3
57
64
J47
ICD-10 Finland
Bronchiectasis
145.9
31.5
32
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
57.1
31.2
36
9
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
39.7
30.4
38
14
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
19.7
30.3
48
40
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
11.9
28.5
61
99
R03AK06
ATC
salmeterol and fluticasone; inhalant
14.9
28.1
51
58
J45.0
ICD-10 Finland
Predominantly allergic asthma
20.4
25.5
39
28
R03BA05
ATC
fluticasone; inhalant
11.4
25.1
53
80
H25.1
ICD-10 Finland
Senile nuclear cataract
39.8
24.2
30
10
J45.1
ICD-10 Finland
Nonallergic asthma
18.9
23.6
37
28
R04.2
ICD-10 Finland
Haemoptysis
28.4
22.2
30
14
R03AC12
ATC
salmeterol; inhalant
29.3
21.7
29
13
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
+∞
21.5
20
*
R03AC02
ATC
salbutamol; inhalant
7.3
21.2
85
322
GD1AD
NOMESCO Finland
Thorax CT examination
25.3
20.8
29
15
B44.9
ICD-10 Finland
Aspergillosis, unspecified
+∞
20.4
19
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
23.7
20.4
29
16
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.2
20.0
61
156
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
6.7
19.7
84
331
R03DC03
ATC
montelukast; oral
9.5
19.5
44
70
R03DA04
ATC
theophylline; systemic, rectal
17.2
19.4
31
24
B44.8
ICD-10 Finland
Other forms of aspergillosis
+∞
19.3
18
*
R03AK08
ATC
formoterol and beclometasone; inhalant
23.5
18.3
26
14
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
19.0
18.3
28
19
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
26.1
18.2
25
12
H02AB04
ATC
methylprednisolone; systemic
9.2
18.1
41
65
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
210.8
18.0
18
*
R03BA01
ATC
beclometasone; inhalant
9.0
17.5
40
64
J01FA06
ATC
roxithromycin; oral
5.8
17.4
68
228
A02BC02
ATC
pantoprazole; systemic
6.2
17.1
90
420
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
12.2
17.1
32
35
XF400
NOMESCO Finland
ECG with 12 standard connections
9.6
17.0
37
54
R50.9
ICD-10 Finland
Fever, unspecified
9.6
16.2
35
50
I25.1
ICD-10 Finland
Atherosclerotic heart disease
98.7
16.0
17
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.6
15.6
46
105
M05BA04
ATC
alendronic acid; oral
17.4
15.4
24
17
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
14.2
15.2
26
23
R06.0
ICD-10 Finland
Dyspnoea
6.3
15.1
46
109
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
20.5
15.0
22
13
I48
ICD-10 Finland
Atrial fibrillation and flutter
42.1
14.9
18
5
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
9.9
14.9
31
41
215
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
14.9
14
*
103
Kela drug reimbursment
Diabetes, insulin-treated
170.5
14.8
15
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
17.6
14.8
23
16
XG410
NOMESCO Finland
Flow-volume spirometry
23.8
14.4
20
10
A49.9
ICD-10 Finland
Bacterial infection, unspecified
9.5
14.1
30
41
ZXD05
NOMESCO Finland
Urgent procedure
5.6
14.1
48
129
J01FF01
ATC
clindamycin; systemic
5.5
14.1
50
141
R03AC13
ATC
formoterol; inhalant
19.4
14.1
21
13
JN4BD
NOMESCO Finland
Extensive body CT
7.6
14.1
35
62
R81
ICPC
Pneumonia
30.1
13.8
18
7
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
7.0
13.5
36
70
J45.8
ICD-10 Finland
Mixed asthma
32.8
13.4
17
6
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
26.3
13.4
18
8
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
11.1
13.1
25
28
J45
ICD-10 Finland
Asthma
9.8
12.7
26
33
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
10.3
12.6
25
30
J46
ICD-10 Finland
Status asthmaticus
42.6
12.5
15
*
R03BA02
ATC
budesonide; inhalant
6.2
12.5
37
82
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.9
12.5
33
63
J01FA09
ATC
clarithromycin; systemic
4.8
12.4
50
158
TPH04
NOMESCO Finland
Cathetrisation of vein
5.7
12.2
39
95
C03CA01
ATC
furosemide; systemic
5.7
12.2
39
95
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
52.5
12.2
14
*
AA1AD
NOMESCO Finland
CT of head and brain
5.9
12.1
37
85
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
4.8
12.0
48
150
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
132.5
11.6
12
*
J01AA02
ATC
doxycycline; systemic
5.5
11.2
101
650
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
7.2
11.2
28
49
GDC00
NOMESCO Finland
Lobectomy of lung
48.3
11.2
13
*
Z2446
NOMESCO Finland
Social worker
20.3
11.1
16
9
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
20.3
11.1
16
9
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.5
11.0
30
59
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
24.3
11.0
15
7
R03BA08
ATC
ciclesonide; inhalant
8.6
11.0
24
34
H02AB07
ATC
prednisone; oral
6.6
10.8
29
56
J01FA10
ATC
azithromycin; systemic
3.8
10.7
75
378
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
120.3
10.6
11
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
36.2
10.6
13
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
10.6
10
*
N03AX16
ATC
pregabalin; oral
5.0
10.5
37
99
WX408
NOMESCO Finland
General anesthesy, balanced
4.2
10.5
48
167
WX892
NOMESCO Finland
Monitored bed care
11.7
10.5
19
19
ZX120
NOMESCO Finland
Intravenous
7.9
10.4
24
37
49300
ICD-8 Finland
Asthma, bronchiale
18.9
10.2
15
9
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
44.1
10.2
12
*
127
Kela drug reimbursment
Transplant complication
44.1
10.2
12
*
C07AB07
ATC
bisoprolol; oral
4.0
10.0
49
178
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.6
9.6
29
65
A10AE04
ATC
insulin glargine; parenteral
108.4
9.6
10
*
A02BC01
ATC
omeprazole; systemic
4.2
9.6
42
139
B01AA03
ATC
warfarin; systemic
7.3
9.5
23
38
J02AC04
ATC
posaconazole; systemic
+∞
9.5
9
*
J17.2*B44.1
ICD-10 Finland
Pneumonia in other aspergillosis
+∞
9.5
9
*
WX002
NOMESCO Finland
Sedation and analgesia
4.8
9.4
34
93
Z2221
NOMESCO Finland
Medical doctor
4.1
9.3
42
142
J01.0
ICD-10 Finland
Acute maxillary sinusitis
4.6
9.2
35
100
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
40.1
9.2
11
*
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
40.1
9.2
11
*
Z01.8
ICD-10 Finland
Other specified special examinations
4.5
9.1
35
101
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.3
8.9
36
109
XW000
NOMESCO Finland
Bone marrow biopsy
13.0
8.9
15
13
ZXE00
NOMESCO Finland
One hour or less
3.6
8.8
51
209
N02BE01
ATC
paracetamol; systemic, rectal
4.6
8.8
101
700
R03AK07
ATC
formoterol and budesonide; inhalant
4.6
8.7
32
88
J01CA04
ATC
amoxicillin; systemic
4.0
8.7
96
639
A02BC05
ATC
esomeprazole; systemic
3.4
8.6
55
242
R03BB01
ATC
ipratropium bromide; inhalant
12.1
8.6
15
14
H26.4
ICD-10 Finland
After-cataract
96.7
8.5
9
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
96.7
8.5
9
*
207
Kela drug reimbursment
Chronic arrhythmias
96.7
8.5
9
*
ZXA05
NOMESCO Finland
Left side
4.1
8.5
36
114
WX302
NOMESCO Finland
Thoracal epidural anesthesy
9.3
8.4
17
21
Z3231
NOMESCO Finland
Registered nurse
4.0
8.4
38
127
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
8.4
8
*
J01FA15
ATC
telithromycin; oral
5.8
8.4
24
50
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
13.1
8.3
14
12
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
18.9
8.3
12
7
H25.8
ICD-10 Finland
Other senile cataract
36.1
8.2
10
*
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
36.1
8.2
10
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
8.0
8.1
18
26
J02AC01
ATC
fluconazole; systemic
3.4
8.1
49
207
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
10.6
8.1
15
16
A07AA02
ATC
nystatin; oral
7.7
8.0
18
27
UDH02
NOMESCO Finland
Rhinopharyngoscopy
9.1
7.9
16
20
J01MA02
ATC
ciprofloxacin; systemic
3.2
7.9
55
256
A02BC03
ATC
lansoprazole; oral
3.7
7.9
40
145
ZXE40
NOMESCO Finland
More than seven and less than nine hours
48.2
7.8
9
*
L04AA06
ATC
mycophenolic acid; systemic
48.2
7.8
9
*
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
13.1
7.8
13
11
WW200
NOMESCO Finland
Immunization
20.0
7.8
11
6
N02AA05
ATC
oxycodone; systemic
4.4
7.8
29
81
TPH07
NOMESCO Finland
Cathetrisation of artery
6.0
7.7
21
41
R49.01
ICD-10 Finland
Functional dysphonia
27.0
7.7
10
*
JN4CD
NOMESCO Finland
Very extensive body CT
7.8
7.6
17
25
R01AD09
ATC
mometasone; nasal
3.1
7.6
57
277
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
14.7
7.6
12
9
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
14.7
7.6
12
9
ZXE30
NOMESCO Finland
More than five and less than seven hours
10.4
7.5
14
15
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
85.2
7.5
8
*
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
85.2
7.5
8
*
I50.9
ICD-10 Finland
Heart failure, unspecified
12.0
7.5
13
12
A28
ICPC
Limited function/disability NOS
5.7
7.4
21
43
R4110
NOMESCO Finland
Physiotherapy
3.5
7.4
40
153
XG474
NOMESCO Finland
Exhalation nntrogen oxide
17.1
7.4
11
7
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
17.1
7.4
11
7
J85.2
ICD-10 Finland
Abscess of lung without pneumonia
+∞
7.4
7
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
+∞
7.4
7
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
21.7
7.3
10
5
P01BA02
ATC
hydroxychloroquine; oral
13.2
7.3
12
10
A41.9
ICD-10 Finland
Sepsis, unspecified
32.2
7.3
9
*
R03AC03
ATC
terbutaline; inhalant
4.9
7.3
24
59
B01AB05
ATC
enoxaparin; parenteral
3.4
7.2
41
162
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
6.5
7.1
18
32
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.4
7.1
38
144
TDM10
NOMESCO Finland
Puncture of maxillary antrum
9.2
7.1
14
17
J01DB01
ATC
cefalexin; oral
3.3
7.0
93
642
B01AC04
ATC
clopidogrel; oral
10.3
7.0
13
14
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
12.0
7.0
12
11
H02AB09
ATC
hydrocortisone; systemic
18.0
6.9
10
6
A10BA02
ATC
metformin; oral
18.0
6.9
10
6
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
18.0
6.9
10
6
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
24.1
6.8
9
*
L04AD01
ATC
ciclosporin; systemic
24.1
6.8
9
*
R03DC01
ATC
zafirlukast; oral
24.1
6.8
9
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
13.3
6.7
11
9
R03AK11
ATC
formoterol and fluticasone; inhalant
13.3
6.7
11
9
C01DA14
ATC
isosorbide mononitrate; oral
11.0
6.7
12
12
ZXA10
NOMESCO Finland
Bilateral
4.4
6.6
24
65
Z96.1
ICD-10 Finland
Presence of intraocular lens
9.0
6.5
13
16
A01AB04
ATC
amphotericin B; local oral
9.0
6.5
13
16
WX872
NOMESCO Finland
Intensive care
15.4
6.5
10
7
A08
ICPC
Swelling
15.4
6.5
10
7
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
73.6
6.5
7
*
Z3226
NOMESCO Finland
Physiotherapist
3.8
6.5
28
89
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
12.0
6.4
11
10
SPAT1255
SPAT
Intravenous administration of medicine
7.8
6.4
14
20
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
28.3
6.3
8
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
6.3
6
*
J96.0
ICD-10 Finland
Acute respiratory failure
+∞
6.3
6
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
+∞
6.3
6
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
+∞
6.3
6
*
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
+∞
6.3
6
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
+∞
6.3
6
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
6.2
6.3
16
29
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.2
6.3
16
29
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
7.4
6.2
14
21
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
7.4
6.2
14
21
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
13.5
6.2
10
8
R01AD01
ATC
beclometasone; nasal
4.0
6.2
25
75

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
64
26
47.52
96.76
7.1
3.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
75
80
20.80
70.73
4.6
1.2
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
49
35
21.86
56.79
4.6
2.1
g/l
9.4
10.5
0.70
44
28
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
38
18
29.42
52.58
2.5
1.0
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
52
7
121.94
50.55
6.6
4.6
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
69
102
13.29
50.22
3.9
1.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
57
68
14.15
48.19
3.0
1.3
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
93
213
12.83
46.97
17.5
3.9
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
56
70
13.30
45.62
3.1
1.3
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
31
13
31.00
44.52
3.3
1.5
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
30
12
32.20
43.76
3.3
1.5
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
110
350
14.93
39.80
17.3
3.6
e9/l
0.7
0.6
5.00
105
293
(3023368) Bacteria identified in Blood by Culture
78
174
9.71
38.94
11.3
3.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
59
97
10.31
38.35
3.2
2.0
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
44
56
11.37
34.64
5.6
9.3
mmol/l
2.2
0.7
1.21
36
48
(3019060) Gas panel - Arterial blood
32
27
15.40
32.91
4.7
3.0
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
32
5
83.90
29.50
7.6
2.8
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
30
28
13.63
28.87
2.5
1.9
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
22
15
17.45
25.10
1.4
1.1
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
27
5
67.41
24.13
2.1
1.2
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
52
123
6.38
22.77
2.4
1.6
mg/l
3.4
2.9
0.62
45
105
(3032080) INR in Blood by Coagulation assay
77
263
5.73
22.17
11.3
4.0
inr
1.3
1.1
0.64
21
62
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
90
351
6.08
22.13
13.1
5.6
mmol/l
1.2
1.2
3.29
84
295
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
26
9
35.61
20.58
1.9
1.4
—
—
—
0
0
(3018418) pH of Serum or Plasma
66
209
5.38
20.48
7.0
3.3
ph
7.4
7.4
—
10
34
(3007853) Bacteria identified in Skin by Aerobe culture
38
73
6.94
20.36
2.9
1.3
—
—
—
0
0
(40758558) Short blood count panel - Blood
63
196
5.30
19.87
21.3
6.0
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
17
11
17.63
19.71
1.8
1.2
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
17
11
17.63
19.71
1.8
1.2
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
70
245
5.02
18.92
2.5
1.8
nmol/l
78.4
79.5
0.11
64
211
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
22
6
43.63
18.28
2.0
1.2
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
22
7
37.37
17.70
1.5
1.6
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
23
9
30.67
17.62
3.5
1.3
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
46
120
5.38
17.60
3.7
2.0
ng/l
410.9
213.5
0.31
40
79
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
18
16
12.90
17.48
1.8
1.4
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
21
24
10.24
17.27
1.6
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
18
17
12.13
16.81
3.2
2.4
u/ml
0.2
0.3
—
9
7
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
21
7
35.35
16.71
1.5
1.6
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
22
9
29.02
16.65
6.4
2.2
—
—
—
0
0
(3012544) pH of Venous blood
26
41
7.68
16.53
4.1
2.9
—
—
—
0
0
(4010399)
30
59
6.31
15.45
2.0
1.4
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
15
12
14.00
15.41
1.7
2.5
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
22
31
8.34
15.34
2.0
1.9
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
81
358
4.35
15.24
22.8
5.8
e9/l
0.0
0.0
0.18
69
290
(3007164) IgA [Mass/volume] in Serum or Plasma
41
109
5.03
15.13
2.0
1.3
g/l
2.6
2.5
0.18
32
64
(46235355) HIV 1 and 2 tests - Meaningful Use set
38
96
5.18
14.88
1.9
1.6
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
21
29
8.44
14.87
8.1
15.2
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
58
208
4.23
14.47
7.9
3.3
u/l
28.1
34.6
1.08
58
202
(3002179) Metamyelocytes/100 leukocytes in Blood
25
45
6.64
13.98
7.9
3.0
%
0.1
0.2
—
7
11
(3017181) Myelocytes/100 leukocytes in Blood
26
49
6.38
13.90
9.3
3.4
%
0.4
0.6
—
10
14
(36304419) Bacteria [Presence] in Urine
54
193
4.08
13.38
4.3
2.5
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
58
222
3.91
12.96
4.5
2.6
e6/l
108.8
107.8
0.00
48
167
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
65
274
3.74
12.49
4.5
2.4
—
—
—
0
0
(3006184) Hemoglobin [Mass/volume] in Capillary blood
15
17
9.84
12.25
1.7
1.2
g/l
113.4
144.4
—
8
10
(3030467) Casts [#/volume] in Urine by Automated count
54
205
3.80
12.08
4.5
2.5
e6/l
0.8
0.5
0.21
45
146
(44790048)
16
7
25.79
11.89
2.9
1.6
—
—
—
0
0
(44806118)
16
7
25.79
11.89
2.9
1.6
—
—
—
0
0
(44790047)
16
7
25.79
11.89
2.9
1.6
—
—
—
0
0
(44790049)
16
7
25.79
11.89
2.9
1.6
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
18
9.29
11.73
2.3
2.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
23
46
5.86
11.49
4.7
11.3
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
15
6
27.98
11.43
3.1
1.2
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
14
16
9.69
11.33
3.2
1.3
%
88.2
89.5
0.06
14
16
(3021440) Promyelocytes/100 leukocytes in Blood
23
48
5.61
10.96
10.0
3.4
%
0.0
0.0
—
9
13
(3018095) Leukocytes [#/volume] in Urine
60
257
3.48
10.96
5.2
2.9
e6/l
16.0
50.7
1.30
50
180
(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
15
7
23.98
10.96
4.1
1.6
—
—
—
0
0
(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection
15
7
23.98
10.96
4.1
1.6
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
30
80
4.58
10.77
1.5
1.1
titre
190.0
335.4
—
8
13
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
63
282
3.39
10.66
2.3
1.5
pmol/l
97.1
102.0
0.38
43
147
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
21
43
5.63
10.19
2.9
1.4
—
—
—
0
0
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
12
13
10.07
10.03
3.3
1.3
%
232.7
178.4
1.16
12
13
(3026782) Osmolality of Urine
39
133
3.76
10.00
3.0
2.2
mosm/kgh2o
522.5
602.3
1.70
33
107
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
16
27
6.62
9.37
7.2
12.5
mmol/l
25.8
25.0
0.23
16
27
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
12
15
8.71
9.01
6.2
3.3
ug/l
425.7
424.3
0.00
12
15
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
35
120
3.62
8.81
4.3
2.5
e6/l
0.2
1.4
0.81
25
66
(3025159) Blasts/100 leukocytes in Blood
20
45
5.07
8.71
10.7
3.5
%
0.0
0.0
—
9
12
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
12
6
21.83
8.64
3.9
1.3
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
12
6
21.83
8.64
3.9
1.3
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
12
6
21.83
8.64
3.9
1.3
—
—
—
0
0
(3000492) Spirometry study
28
85
3.92
8.37
2.2
1.3
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
55
256
2.99
8.30
4.2
1.9
ng/l
36.1
21.3
0.50
47
168
(3037467) Urinalysis macro (dipstick) panel - Urine
91
558
3.10
8.23
6.2
3.1
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
11
14
8.49
8.11
1.3
1.5
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
11
14
8.49
8.11
1.6
1.2
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
11
14
8.49
8.11
1.1
2.1
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
32
112
3.46
7.74
1.6
1.4
nmol/l
1030.3
1081.4
0.12
25
81
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
34
127
3.27
7.39
4.4
2.3
e6/l
0.6
0.9
0.28
24
70
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
0
+∞
7.35
1.9
0.0
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
10
13
8.25
7.22
1.2
2.8
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
51
244
2.79
7.14
7.9
2.2
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
18
44
4.59
7.08
3.8
2.0
e9/l
74.7
63.4
0.59
13
35
(40760892) CBC W Ordered Manual Differential panel - Blood
35
141
3.03
6.65
12.3
3.0
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
11
18
6.58
6.54
9.5
3.9
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
10
7
15.33
6.51
2.6
1.7
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
69
398
2.56
6.49
7.7
3.5
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
9
5
19.16
6.36
1.3
1.2
—
—
—
0
0
(3044889) 12 lead EKG panel
93
623
2.73
6.34
5.7
2.7
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
43
199
2.73
6.31
5.8
2.1
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
6
0
+∞
6.29
1.8
0.0
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
6
0
+∞
6.29
1.8
0.0
—
—
—
0
0
(3024471) HLA-A [Type]
6
0
+∞
6.29
1.2
0.0
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
29
108
3.17
6.27
1.7
1.5
pmol/l
473.8
102247605.6
0.49
24
89
(3026493) Urate [Moles/volume] in Serum or Plasma
40
180
2.77
6.18
6.5
2.0
umol/l
342.4
16802.3
2.05
33
161
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
10
9
11.91
5.90
1.5
1.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
41
194
2.63
5.69
3.4
2.3
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
9
7
13.68
5.67
2.1
1.0
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
25
5.19
5.62
2.7
2.7
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
17
48
3.92
5.54
2.2
1.6
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
76
482
2.39
5.52
3.4
2.3
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
8
5
16.90
5.48
1.3
1.2
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
9
8
11.97
5.38
7.1
3.1
kpa
7.4
9.1
—
9
8
(3008757) Leukocyte morphology finding [Identifier] in Blood
9
8
11.97
5.38
11.1
2.9
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
9
8
11.97
5.38
1.3
1.3
—
—
—
0
0
(36659890) Mycobacterial identification panel - Specimen by Molecular genetics method
5
0
+∞
5.24
1.2
0.0
—
—
—
0
0
(3024932) HLA-DR beta [Type]
5
0
+∞
5.24
1.4
0.0
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
8
6
14.08
5.15
2.5
2.3
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
8
7
12.07
4.85
3.0
1.0
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
8
7
12.07
4.85
4.3
1.4
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
13
33
4.27
4.84
1.3
1.5
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
35
169
2.47
4.57
3.9
2.1
mg/mmol
17.7
12.2
0.20
25
96
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
12
30
4.31
4.55
6.4
1.9
—
—
—
0
0
(4035726)
22
85
2.91
4.41
1.4
1.2
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
12
31
4.16
4.36
4.4
13.7
%
0.7
0.7
0.19
12
31
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
12
31
4.16
4.36
4.4
13.8
%
1.3
1.2
0.34
12
31
(3014007) Fractional oxyhemoglobin in Arterial blood
12
31
4.16
4.36
4.4
13.8
%
94.0
95.5
0.85
12
31
(3042111) Morphology [Interpretation] in Bone marrow Narrative
8
9
9.38
4.34
2.3
1.9
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
7
6
12.23
4.32
2.1
2.3
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
7
6
12.23
4.32
2.1
2.3
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
7
6
12.23
4.32
2.1
2.3
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
7
6
12.23
4.32
2.1
2.3
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
7
6
12.23
4.32
2.1
2.3
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
7
6
12.23
4.32
2.1
2.2
—
—
—
0
0
(3015736) pH of Urine
49
286
2.14
4.05
3.5
2.4
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
32
157
2.38
4.00
3.3
1.8
mg/l
1785.9
604.7
0.29
21
83
(3003327) Ova and parasites identified in Stool by Light microscopy
9
15
6.36
3.89
2.4
1.5
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
6
5
12.48
3.80
1.3
1.0
u/ml
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
10
26
4.08
3.59
3.7
1.8
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
97
754
2.13
3.47
62.7
10.9
%
14.7
13.5
7.86
97
733
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
79
571
1.98
3.47
3.3
2.9
pmol/l
14.9
15.0
0.05
68
513
(40768804) Tissue Pathology biopsy report
55
352
1.98
3.44
2.3
2.1
—
—
—
0
0
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
7
10
7.32
3.41
1.3
1.3
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
59
391
1.93
3.31
4.0
2.4
estimate
0.0
0.0
0.00
14
67
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
18
73
2.70
3.30
2.1
1.5
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
59
393
1.92
3.24
5.8
3.2
estimate
0.0
0.0
0.00
14
64
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
19
81
2.58
3.16
6.4
2.1
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
59
396
1.90
3.15
4.1
2.4
estimate
0.0
0.0
0.00
14
67
(3048689) Calprotectin [Mass/mass] in Stool
14
51
2.96
3.10
1.3
1.2
ug/g
190.8
90.9
—
8
35
(3029634) Reagin Ab [Titer] in Serum by VDRL
6
8
7.79
3.09
2.0
2.5
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
6
8
7.79
3.09
2.0
2.6
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
7
12
6.09
3.06
2.3
1.7
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
5
5
10.32
3.00
1.4
1.8
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
25
128
2.18
2.79
1.2
1.1
u/ml
1.3
0.6
—
9
39
(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
5
6
8.60
2.77
1.4
1.3
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
5
6
8.60
2.77
1.4
1.0
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
7
14
5.22
2.76
2.4
1.5
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
18
80
2.45
2.75
1.8
1.1
—
—
—
0
0
(3022313) Gas panel - Capillary blood
10
32
3.30
2.71
16.8
3.3
—
—
—
0
0
(4306422)
5
7
7.37
2.57
1.2
1.3
—
—
—
0
0
(3019225) pH of Specimen
18
83
2.36
2.55
9.6
3.9
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
102
847
1.95
2.52
55.6
9.8
%
38.0
40.6
3.19
72
625
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
7
17
4.29
2.39
3.1
2.9
%
1.5
1.0
—
7
17
(3024889) Methemoglobin/Hemoglobin.total in Venous blood
7
17
4.29
2.39
3.1
2.9
%
0.8
0.6
—
7
17
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
5
8
6.44
2.39
1.4
1.3
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
5
8
6.44
2.39
1.2
1.0
—
—
—
0
0
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
5
8
6.44
2.39
1.0
1.0
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
5
8
6.44
2.39
1.2
1.1
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
5
8
6.44
2.39
13.8
4.8
—
—
—
0
0
(3020891) Body temperature
6
13
4.78
2.30
2.5
2.2
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
6
13
4.78
2.30
10.8
1.6
%
59.3
46.2
—
6
13
(3024928) Oxygen saturation in Venous blood
6
13
4.78
2.30
2.3
4.2
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
5
9
5.72
2.23
2.2
1.2
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
114
1000
2.14
2.17
52.5
9.8
mmol/l
138.9
140.0
4.18
114
960
(3023103) Potassium [Moles/volume] in Serum or Plasma
114
1004
2.10
2.08
54.2
9.9
mmol/l
4.0
4.0
1.09
114
963
(40761511) CBC panel - Blood by Automated count
113
993
2.06
2.06
41.6
8.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
29
175
1.85
2.05
3.3
2.6
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
9
34
2.77
1.90
1.3
1.3
—
—
—
0
0
(3013512) EKG study
35
230
1.71
1.86
6.5
2.7
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
33
214
1.73
1.84
4.2
2.0
—
—
—
0
0
(3004490) Bicarbonate [Moles/volume] standard in Capillary blood
8
30
2.77
1.75
16.9
4.0
mmol/l
26.4
24.7
—
8
30
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
12
55
2.30
1.73
4.3
3.1
mmol/l
1.3
1.2
0.41
12
43
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
114
1021
1.95
1.72
30.7
7.1
u/l
24.3
24.5
0.09
114
964
(3020564) Creatinine [Moles/volume] in Serum or Plasma
114
1025
1.91
1.64
56.3
10.8
umol/l
80.5
79.2
0.18
114
1025
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
19
110
1.85
1.53
1.2
1.2
u/ml
1.1
9.3
—
6
41
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
20
118
1.82
1.52
1.3
1.2
iu/ml
26.4
39.9
—
5
37
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
103
909
1.64
1.47
40.7
8.5
ml/min/173m2
79.3
78.4
0.18
97
713
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
91
783
1.54
1.43
4.2
3.2
mu/l
1.7
2.0
1.50
81
693
(36660697) Celiac disease serology panel - Serum
9
44
2.12
1.29
1.1
1.2
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
12
63
2.00
1.27
5.7
2.5
ml/min/173m2
35.8
70.3
—
5
22
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
18
109
1.76
1.27
1.2
1.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
41
306
1.50
1.26
4.3
2.5
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
12
64
1.96
1.22
3.8
2.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
8
39
2.12
1.17
2.5
1.7
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
35
0.00
1.17
0.0
1.6
—
—
—
0
0
(3022145) Colonoscopy Study observation
14
84
1.75
1.02
1.1
1.3
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
29
216
1.44
0.89
4.2
2.6
estimate
0.0
0.0
0.00
13
66
(3019150) Specific gravity of Urine by Refractometry
22
157
1.48
0.84
4.3
2.8
kg/l
1.0
1.0
—
6
22
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
40
1.79
0.72
1.0
1.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
27
341
0.74
0.68
3.3
2.3
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
87
940
0.77
0.64
4.3
3.6
mmol/l
1.5
1.5
0.15
80
853
(3049717) Cytology report of Urine Cyto stain
6
35
1.75
0.58
2.8
2.8
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
6
35
1.75
0.58
2.3
1.5
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
5
89
0.54
0.58
2.0
1.6
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
6
37
1.65
0.56
5.3
2.0
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
114
1087
1.40
0.55
72.4
12.9
e9/l
279.6
240.0
3.52
114
1039
(3035941) MCH [Entitic mass]
114
1088
1.39
0.54
71.5
12.9
pg
29.8
30.5
3.05
114
1057
(3024731) MCV [Entitic volume]
114
1088
1.39
0.54
71.6
12.9
fl
91.4
91.1
0.17
114
1057
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
15
109
1.43
0.54
4.7
4.9
ug/l
3.1
54.4
0.71
15
90
(3000963) Hemoglobin [Mass/volume] in Blood
114
1090
1.37
0.51
72.0
12.9
g/l
124.0
138.9
15.22
114
1057
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
89
945
0.82
0.45
4.2
3.6
mmol/l
4.6
4.9
1.53
82
854
(40768443) Skin Pathology biopsy report
5
31
1.64
0.43
1.0
1.3
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
2.6
—
2.9
—
0
15
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
(40761535) Cells panel - Urine sediment
9
66
1.39
0.39
3.8
2.5
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
91
959
0.83
0.39
4.6
4.0
mmol/l
2.6
3.0
2.26
84
870
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
55
498
1.18
0.37
5.1
5.0
ug/l
1.7
4.3
0.79
46
440
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
6
46
1.32
0.33
1.7
2.1
—
—
—
0
0
(3002256) Pathology report gross observation
16
132
1.24
0.27
1.3
1.3
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
9
74
1.23
0.26
2.1
1.6
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
29
259
1.15
0.23
1.4
1.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
5
41
1.23
0.22
1.6
1.8
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
6.6
—
23.4
—
0
14
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
39
420
0.90
0.18
3.8
4.4
%
22.1
21.5
0.09
17
232
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
5
67
0.74
0.17
1.2
1.4
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
29
317
0.89
0.17
3.8
3.0
ug/l
0.7
0.8
0.20
21
226
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
11
93
1.20
0.15
1.5
1.4
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
87
845
1.09
0.14
5.4
3.5
mmol/mol
40.8
36.9
3.59
80
775
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
87
893
0.92
0.12
4.0
3.3
mmol/l
1.4
1.2
1.16
81
811
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
10
101
0.99
0.00
9.9
4.4
—
—
—
0
0
(3022621) pH of Urine by Test strip
5
50
1.00
0.00
4.8
1.8
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
4.2
—
47.0
—
0
6
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
(4024509)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint ABPA and mortality.

Females

Parameter HR [95% CI] p-value
ABPA 3.293 [2.26, 4.8] < 0.001
Birth year 0.998 [0.99, 1.01] 0.603

During the follow-up period (1.1.1998 — 31.12.2019), 68 out of 184 females with ABPA died.

Males

Parameter HR [95% CI] p-value
ABPA 4.575 [3.14, 6.67] < 0.001
Birth year 0.989 [0.98, 1.0] 0.071

During the follow-up period (1.1.1998 — 31.12.2019), 146 out of 299 males with ABPA died.

Mortality risk

Mortality risk for people of age

years, who have ABPA.

N-year risk Females Males
1 0.361% 0.785%
5 2.115% 5.488%
10 5.29% 13.321%
15 10.035% 24.056%
20 16.778% 38.985%

Relationships between endpoints

Index endpoint: ABPA – Allergic bronchopulmonary aspergillosis (ABPA)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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